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International Journal of Integrated Health Sciences
Published by Universitas Padjadjaran
ISSN : 23021381     EISSN : 23384506     DOI : 10.15850/ijihs
Core Subject : Health,
Health Professions
International Journal of Integrated Health Sciences (IJIHS) is a peer-review journal which publishes original articles, medical research, clinical research and case report. This journal is supported by Faculty of Medicine Universitas Padjadjaran and was launched on September 22nd 2012 and firstly published on July 2013. The first and second publications in 2013 and 2014 were published annually. In 2015 IJIHS published twice in a year, March and September.
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Search results for , issue "Vol 12, No 1 (2024)" : 10 Documents clear
Interpretation of Platelet Histograms and Its Correlation with Peripheral Smear in Data Showing Thrombocytopenia Shinde, Aparna; Modi, Alisha; Patil, Amruta
International Journal of Integrated Health Sciences Vol 12, No 1 (2024)
Publisher : Faculty of Medicine Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15850/ijihs.v12.n1.3773

Abstract

Objective: To analyze the significance of platelet histograms and peripheral smears in understanding thrombocytopenia and compare them for the incidence of pseudothrombocytopenia.Methods: This prospective study was conducted in the Department of Pathology at a tertiary care medical institute. The study included 200 cases of thrombocytopenia. Platelet parameters (PCT, PDW, MPV) were obtained using an autoanalyzer, and peripheral smears were examined manually. Thrombocytopenia cases were classified into hyper-destructive, hypo-productive, and abnormal pooling categories based on etiology and platelet histogram patterns. The incidence of pseudothrombocytopenia was also compared. A P value of less than 0.05 was considered statistically significant. Results: The gender distribution showed a male preponderance (56% male, 44% female). The mean age of the patients was 26.8 years. The study found hyper-destructive thrombocytopenia to be the most common type, with viral fever, sepsis, and malaria being the common etiologies for this type of thrombocytopenia. Histogram analysis revealed distinct patterns for different types of thrombocytopenia. The study also noted a higher incidence of pseudothrombocytopenia in automated analysis compared to manual methods, with a statistically significant difference.Conclusion: Platelet histograms combined with peripheral smear analysis provide crucial information about the etiology and nature of thrombocytopenia. This integrated approach enhances diagnostic accuracy and aid in effective patient management.
Subclinical Left Ventricular Dysfunction Prevention in Breast Cancer Patients after FAC Chemotherapy: A Carvedilol Trial Astuti, Astri; Sumantra, I Gede; Aafiyah, Adila; Abdurahman, R. Maman; Sihite, Teddy Arnold; Akbar, Mohammad Rizki; Hasan, Melawati; Martanto, Erwan
International Journal of Integrated Health Sciences Vol 12, No 1 (2024)
Publisher : Faculty of Medicine Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15850/ijihs.v12.n1.3570

Abstract

Objective:  To assess the cardioprotective effects of Carvedilol in preventing subclinical left ventricular dysfunction (SLVD) in breast cancer patients after completing FAC chemotherapy.Methods: This prospective study employed a quasi-experimental clinical trial conducted from September 2018 to May 2019. Breast cancer patients receiving FAC chemotherapy were divided into two groups: intervention (IG) and control (CG). The IG received Carvedilol 6.25 mg b.i.d., which was increased every three weeks until reaching a tolerated dose. The study evaluated changes in left ventricular global longitudinal strain (GLS) and the incidence of SLVD (GLS reduction ≥15% and GLS >-18%) 24 weeks after initiating the FAC regimen.Result: Of the 81 women enrolled in the study, 31 were in the IG. No significant changes in GLS were observed during or after completing FAC chemotherapy in the IG, whereas the CG showed contradictory results. At the end of the follow-up period, the delta GLS reduction was lower in the IG (0.7; 95% CI -0.60, 3.60) compared to the CG (3.00; 95% CI -2.16, 4.19), with a p-value of 0.035. Similarly, the percentage reduction in GLS was 3.6% in the IG and 14.29% in the CG, resulting in a p-value of 0.05. The incidence rate of SLVD (GLS reduction ≥15% and GLS > -18%) was lower in the IG (41.9% and 25.8%) than in the CG (58% and 48%).Conclusion: Carvedilol may have a cardioprotective effect in preventing the incidence of SLVD, as evaluated by GLS reduction and changes, in women with breast cancer after completing a full cycle of the FAC regimen.
Study of Clinical and Demographic Profile of Scrub Typhus Patients Admitted to a Tertiary Care Hospital in Central India Dahiphle, A. V.; Achliya, Amit; Chhajed, Neel; Rode, Vikram; Bhise, Kasturi
International Journal of Integrated Health Sciences Vol 12, No 1 (2024)
Publisher : Faculty of Medicine Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15850/ijihs.v12.n1.3788

Abstract

Objectives: To study epidemiological characteristics, clinical features, laboratory findings, and clinical outcomes in cases of scrub typhus. Additionally, the study aims to identify the predictors of disease severity.Methods: This cross-sectional study was conducted in the Department of General Medicine at Dr PDM Medical College in Amaravati, India. The study duration was 6 months, from July 2023 to December 2023. All clinically confirmed patients with scrub typhus were evaluated through history, clinical examination, and appropriate laboratory investigations. The clinical and laboratory profiles, hospital course, and outcomes were analyzed. Organ dysfunction upon admission was assessed using the sequential organ failure assessment (SOFA) score.Results: A total of 200 cases were included in the study. The majority of the cases were in the age range of 31-40 years, and most of them were males. The highest number of scrub typhus cases occurred in September. The most common presenting symptoms were fever (81%), followed by nausea (37.5%), generalized weakness (34%), abdominal pain, eschar (21.5%), breathlessness, and cough (21% each), headache (19%), vomiting (15%), and altered sensorium (4.5%). The majority of patients (72.5%) did not experience any complications, while 55 patients (27.5%) developed multi-organ dysfunction syndrome (MODS) as a complication. The mortality rate was 1%.Conclusion: Scrub typhus is a significant cause of acute febrile illness in the Vidarbha region of Maharashtra. It can present with various clinical manifestations, with or without an eschar. Early diagnosis and appropriate treatment of these cases can lead to minimal complications.
Modified Surgical Treatment for Achilles Tendon Rupture Secondary to Insertional Achilles Tendinopathy Using Midline Dorsal Approach Naik, Nagesh; Rahate, Vaijanath; Ghorpade, Kapil R.; Patil, Jaydeep; Patil, Shantanu
International Journal of Integrated Health Sciences Vol 12, No 1 (2024)
Publisher : Faculty of Medicine Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15850/ijihs.v12.n1.3698

Abstract

Objective: To assess the pain relief and functional outcomes of patients who undergo surgical management of Achilles tendon rupture secondary to insertional Achilles tendinopathy and associated conditions using a midline dorsal approach.Methods: This prospective observational study included 30 patients diagnosed with Achilles tendon rupture secondary to insertional Achilles tendinopathy. This study recorded risk factors, predisposing factors, and co-morbidities for all cases. Pain relief and functional improvement were assessed by comparing Visual Analogue Scale (VAS) scores and American Orthopedic Foot and Ankle Score (AOFAS) at the time of presentation and at the final follow-up. This study conducted statistical analysis using SPSS 21.0 software, with a significance level of p<0.05.Results: Of the participants, 17 (56.67%) were male and 13 (43.13%) were female, resulting in a male-to-female ratio of 1:0.76. The mean age of male and female patients was comparable (p=0.7515). The majority of patients (60%) were overweight, while 9 (30%) were obese, and 3 (10%) had a normal body mass index. This study observed a significant reduction in pain and functional improvement in the studied cases, as evidenced by a statistically significant reduction in VAS scores and improvements in AOFAS. Eight (26.66%) patients experienced minor complications that could be managed conservatively, but no major complications were observed.Conclusion: Modified surgical treatment of Achilles tendon rupture secondary to insertional Achilles tendinopathy using a midline dorsal approach leads to significant improvements in pain and functional outcomes, with an acceptable complication rate.
Characteristics of the Mothers on Stunting Toddlers 12-36 Months West Bandung Regency, Indonesia Elba, Fardila; Che Hassan, Hafizah; Umar, Nur Syazana
International Journal of Integrated Health Sciences Vol 12, No 1 (2024)
Publisher : Faculty of Medicine Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15850/ijihs.v12.n1.3578

Abstract

Objective: To determine the characteristics of respondents with stunted toddlers aged 12-36 months in the Batujajar and Cihampelas districts of West Bandung District.Methods: A case-control study with a pretest-posttest design was conducted from May to August 2022 in West Bandung Regency, Indonesia. The study included 124 mothers with stunted toddlers, who were divided into two groups - control and treatment - with 62 toddlers each, using simple random sampling.Result: The majority of children under the age of five in this study were female. In the case group, the majority of mothers were in the 20-29 age range (40.3%), while in the control group, the majority were in the 30-39 age range (38.7%). Most mothers in both the control and case groups had a high school education (41.8%). The majority of participating mothers were housewives (85.5%). Childcare was primarily provided by mothers, and most of the resource persons were also mothers.Conclusion: Based on the characteristics observed in this study, the majority of children under the age of five were female in both the case and treatment groups. Most mothers in both groups had a high school education, and the majority of participating mothers were housewives. Childcare was primarily handled by mothers, and most of the resource persons were also mothers.
Case Series on Imaging Features of Trilateral and Quadrilateral Retinoblastoma: What Radiologists Need to Know Fiona, Fiona; Yuli Anandasari, Pande Putu; Margiani, Ni Nyoman
International Journal of Integrated Health Sciences Vol 12, No 1 (2024)
Publisher : Faculty of Medicine Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15850/ijihs.v12.n1.3359

Abstract

Objective: To identify the differences between trilateral and quadrilateral retinoblastoma based on radiologic imaging.Case: We found three cases of retinoblastoma at Sanglah General Hospital. The retinoblastoma patients we found were boys under the age of 5. The first patient presented with swelling, pain, and impaired vision in the right eye. The second and third patients presented with eye protrusion and leukocoria. Computed tomography (CT) imaging revealed a calcified mass in the intraorbital region that extended to the cerebral hemispheres. It may be accompanied by hair-on-end periosteal reaction. In the first patient, the mass extended to the pineal gland. In the second and third patients, the mass extended to the suprasellar and pineal regions.  Trilateral retinoblastoma consists of a primordial midline neuroectodermal tumor that originates in the pineal or suprasellar region. It is an uncommon combination of unilateral or bilateral retinoblastomas. Quadrilateral retinoblastoma, on the other hand, presents with bilateral retinoblastoma and tumors in both the suprasellar and pineal regions. The histopathology of trilateral and quadrilateral retinoblastoma shows a different pattern from retinoblastoma.Conclusion: Retinoblastoma poses one of the most challenging problems due to its distinct patterns of growth, extension, and recurrence. Intracranial metastasis of trilateral and quadrilateral retinoblastoma exhibits a different pattern. The prognosis and diagnosis of retinoblastoma are significantly influenced by clinical examination, radiologic imaging, and histopathology.
Serum Magnesium Levels in Patients Admitted with Septic Shock and Its Correlation with Outcome Premita, Mayengbam; Ajaykumar, Rajkumar; Kireeti, P.; Singh, Seram
International Journal of Integrated Health Sciences Vol 12, No 1 (2024)
Publisher : Faculty of Medicine Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15850/ijihs.v12.n1.3699

Abstract

Objective: To evaluate the initial serum magnesium levels of critically ill septic shock patients upon admission to the intensive care unit (ICU) and correlate these levels with the patients' requirements and outcomes, including ventilator support, length of stay in the ICU, occurrence of cardiac arrhythmias, and mortality rates.Methods: This was an observational study involving 60 patients who were admitted to the medical Intensive Care Unit (ICU) for septic shock. Serum magnesium levels were measured upon admission to the ICU. A comparison was made between patients with normal and abnormal magnesium levels at the time of admission to evaluate the need for vasopressor support, the average duration of assisted ventilation and dialysis, the incidence of arrhythmia, the average length of ICU stay, and mortality rates.Results: Out of the 60 cases studied, there were 42 males (70.00%) and 18 females (30.00%), resulting in a M:F ratio of 1:0.42. The mean age of both male and female patients was found to be comparable. The need for assisted ventilation and renal replacement therapy was found to be comparable in patients with normal and abnormal serum magnesium levels. The number of days for which assisted ventilation was required, the incidence of arrhythmia, the mean duration of ICU and hospital stay, and mortality were significantly higher in patients with abnormal magnesium levels at the time of ICU admission (P<0.05).Conclusion: Abnormal serum magnesium levels are associated with increased morbidity and mortality in critically ill septic shock patients admitted to the ICU.
Risk Factors for Treatment Drop Out Among Pulmonary Tuberculosis Patients at the UPT Public Health Center in Medan Sunggal Zuhair, Raisa Daffa; Ismah, Zata
International Journal of Integrated Health Sciences Vol 12, No 1 (2024)
Publisher : Faculty of Medicine Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15850/ijihs.v12.n1.3544

Abstract

AbstractObjective: To determine the factors contributing to treatment dropout in tuberculosis (TB) patients.Methods: This study utilized a case-control design with a sample size of 81 participants. Univariate, bivariate, and multivariate analyses were conducted, and an accidental sampling technique was employed. The study was conducted at the Public Health Center/Puskesmas Medan Sunggal, in the Medan Sunggal District, City of Medan, and North Sumatra Province. The research took place from February to April 2023.Results: The research analysis revealed a significant relationship between knowledge and family support (p<0.05). However, there was no significant relationship found between drug side effects and treatment dropout (p>0.05). This lack of significance may be attributed to the consistent occurrence of side effects throughout the different stages of treatment.Conclusion: In conclusion, this research demonstrates a significant correlation between patients’ knowledge, family support, and treatment dropout (p<0.05). Conversely, no significant correlation was found between drug side effects and treatment dropout (p>0.05).Keywords: Drug side effect, pulmonary TB, TB treatment drop out
Detection of Leptospira sp. Bacteria and Factors Related to the Incidence of Leptospirosis in Semarang City Diyana, Sutra; Sutiningsih, Dwi; Adi, Mateus Sakundarno; Hitipeuw, Derico
International Journal of Integrated Health Sciences Vol 12, No 1 (2024)
Publisher : Faculty of Medicine Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15850/ijihs.v12.n1.3767

Abstract

Objective: The Case Fatality Rate (CFR) of Leptospirosis in Semarang City has shown a tendency to increase from 2019 to 2022. In 2022, there were 30 cases reported, with 8 deaths (CFR 27%). The purpose of this study was to detect Leptospira sp. bacteria in rats and analyze the risk factors for leptospirosis in Semarang City.Methods: This study employed an observational approach with a Case-Control Study design. The research was conducted in Semarang City from November to December 2023. Non-random sampling techniques were used, specifically the total sampling method, resulting in a sample size of 45 case groups and 45 control groups. Bivariate analysis was performed using the Chi-square test, with a significance level set at <0.05.Results: Based on the Chi-Square test results, the following variables were found to be associated with the incidence of leptospirosis in Semarang City: the presence of rats (p<0.0001), the presence of Leptospira sp. bacteria (p<0.0001), house conditions (p=0.260), sewer condition (p<0.0001), presence of pets (p=0.001), condition of landfills (p=0.001), presence of vegetation (p=0.005), temperature (p=0.299), humidity (p=0.495), lighting (p=0.023), history of wounds (p=0.001), and knowledge level (p=0.025).Conclusion: The risk factors for leptospirosis in Semarang City include the presence of rats, the presence of Leptospira sp. bacteria, sewer conditions, the presence of pets, conditions of landfills, the presence of vegetation, lighting, history of injury, and level of knowledge.
Analysis of the Relationship between Age and Immunization Completeness with Measles Incidence in the City of Medan in 2022 Harahap, Sunnii Irtiyah; Ismah, Zata; Hotmaida, Doris
International Journal of Integrated Health Sciences Vol 12, No 1 (2024)
Publisher : Faculty of Medicine Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15850/ijihs.v12.n1.3552

Abstract

Objective: To analyze the relationship between age and immunization completeness and the occurrence of measles in Medan City in 2022.Methods: This study is quantitative research with a case-control study design. The respondents in this study are the entire population of Medan City. The sample size for this research is 96 respondents, with 48 in the case group and 48 in the control group, all recorded in the measles case report at the Health Department of Medan City in 2022. The study was conducted from January to July 2023.Results: Forty respondents in this study belonged to the toddler group, and most of whom had an incomplete immunization history. Based on chi-square analysis, a significant relationship was found between age and the occurrence of measles (p-value < 0.05), as well as between immunization completeness and the occurrence of measles (p-value < 0.05) with an odds ratio (OR) of 11.0. This means that respondents who are not immunized are 11 times more likely to experience measles compared to those who are immunized. Respondents with incomplete immunization are also 11 times more likely to experience measles compared to those with complete immunization.Conclusion: There is a significant relationship between age and immunization completeness and the occurrence of measles. Respondents with an incomplete immunization history are at 11 times higher risk of experiencing measles compared to those with a complete immunization history. For future research, it is recommended to increase the number of study respondents and further explore and expand on risk factors such as the history of contact with measles cases in the city of Medan.

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