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Journal of the Medical Sciences (Berkala Ilmu Kedokteran)
Core Subject : Science,
Journal of the Medical Sciences (JMedSci) or Berkala Ilmu Kedokteran (BIK) is an international, open-access, and double-blind peer-reviewed journal, published by Faculty of Medicine, Public Health and Nursing, Universitas Gadjah Mada Yogyakarta Indonesia. JMedSci aiming to communicate high-quality articles in the areas of biomedical science from basic to clinical sciences.The journal welcomes papers from original articles, case reports, reviews, and book reviews. All papers published in JMedSci are freely available as downloadable pdf files. The journal began its publication on March 1973 and published quarterly (January, April, July, and October). JMedSci is abstracted and indexed in DOAJ, Crossref, Google Scholar, Sinta, Indonesia One Search. JMedSci is accredited by Directorate of General Higher Education, the Ministry of Research, Technology, and Higher Education, Indonesia
Articles 2,170 Documents
The Role of the medical profession and its support system in the promotion of peace and the prevention of nuclear war Soedibjo Sardadi Soedibjo Sardadi
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 18, No 04 (1986)
Publisher : Journal of the Medical Sciences (Berkala Ilmu Kedokteran)

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Abstract

In this article the author describes the present development of the war machine, and its actual and potential impact on medicine. The effects of nuclear explosion are briefly discussed and the possible roles of the medical profession is brought forth in facing the current global political situation. The ethical and moral foundation of medicine is emphasized in carrying out the professional social responsibility to preserve the comprehensive health of mankind. Key Words: prevention of nuclear war - peace studies - medical polemology - medical effects of nuclear explosion - war medicine
Letak Chalazion Budihardjo Budihardjo
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 12, No 02 (1980)
Publisher : Journal of the Medical Sciences (Berkala Ilmu Kedokteran)

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Abstract

Chalazion cases attending the Eye Clinic of the Gadjah Mada University had been collected during 1978. It was found that the incidence of chalazion was 1,78%. Chalazion at the upper palpebra are more frequent than at the lower.Key Words: chalazion - blepharitis - palpebra - Meibomian glands - excochleation
Factor Vill level given by continuous infusion compared to by bolus in children with hemophilia A undergoing circumcision (case series) Ridwan Sugiarto T Ridwan Sugiarto
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 37, No 04 (2005)
Publisher : Journal of the Medical Sciences (Berkala Ilmu Kedokteran)

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Abstract

Background: hemophilia is the most common hereditary bleeding disorder in children, and can create challenges in the treatment of complicated bleeding episode. Circumcision and other surgical procedures in persons with hemophilia require anticipatory management plan to prevent and treat bleeding prior to, during and following surgery. Prolonged bleeding can be managed by supplement therapy with Factor VIII, administered intravenously by either bolus (BI) or continuous infusion (CI) to achieve hemostatic plasma Factor VIII levels.Objectives: the aim of this study was to compare plasma activity level of factor VIII in relation to the method of intravenous administration.Methods: commencing 4 days post circumcision, five sequential measurements of plasma Factor VIII levels were done at 6 hourly intervals in 4 boys with hemophilia A who received intravenous Factor Vill, either by 81 or Cl.Result: four patients given continuous infusion showed lower level of Factor VIII compared to bolus therapy. Conclusion: bolus therapy has more increased level of Factor VIII compared to continuous infusion. Bleeding was not found in both therapies (Cl or BI). Key words: AHF - continuous infusion - bolus - plasma level
Risk factors related to malaria incidence at Santu’un village, Tabalong District, South Kalimantan Province Junus Widjaja Supargiyono Tri Baskoro Tunggul Satoto
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 43, No 02 (2011)
Publisher : Journal of the Medical Sciences (Berkala Ilmu Kedokteran)

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Abstract

Santu’un Village is one of malaria endemic areas in Muara Uya Sub district, Tabalong District, South KalimantanProvince, Indonesia. Annual Parasite Incidences (APIs) from 2007 to 2009 were 11.4, 82.9, and 25.8‰ respectively.The majority of Muara Uya population are rubber tappers, gold miners and loggers in the forest. Moreover, most ofthe Muara Uya population do not use mosquito nets when sleeping at night. These occupations and communityhabits may contribute in high malaria incidence in Muara Uya. However, study concerning risk factor of malaria hasnot been performed yet. The study was conducted in order to evaluate risk factors that might correlate with malariaincidence in Santu’un village, Muara Uya subdistrict. Two hundred and ninety one subjects were enrolled in thisstudy. Those consisted of 70 people whom microscopically malaria positive and 221 people whom malaria negative.Household visits were conducted to each subject to perform interviews. Data collection of malaria risk factors wasobtained using questionaire. The results indicated that three main occupations, loggers, gold miners and rubbertapper, were significantly represent risk factors of malaria incidence. The community habits that also significantlycorrelated with malaria incidence were the not using of mosquito repellents and not using bed nets. Two clusteringcases were also observed during the year of 2010. The coordinate of the first cluster was 1.863500 S and 115.606700E with diameter of 0.65 km and the coordinate of the second cluster was 1.838667 S and 115.607200 E withdiameter of 0.67 km. In conclusion, in Santu’un village, the risk factor that correlated with the malaria incidencewere loggers, gold miners, rubber tappers. In addition the not using of mosquito repellents and not using bed netswere also risk factors of malaria incidence.Key words: malaria -risk factors-annual parasite incidence-Muara Uya-South Kalimantan
Dengue Hemorrhagic Fever in adolescents and young adults in the Department of Internal Medicine, Gadjah Mada Ahmad H. Asdie Ahmad H. Asdie
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 5, No 02 (1973)
Publisher : Journal of the Medical Sciences (Berkala Ilmu Kedokteran)

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Abstract

A short history of Dengue, the etiology of Dengue Hemorrhagic Fever and the vectors are reviewed. A classification and nomenclature for diseases suspected to be of dengue or chikungunya virus etiology, as suggested by WHO is given.Six cases and two additional cases of Dengue Hemorrhagic Fever in adolescents and young adults are reported.The bone marrow findings in our cases compared with those found in the literature.The pathogenesis of Dengue Hemmorrhagic Fever is reviewed in short.
The association of single nucleotide polymorphism (SNP) rs2922126 within ghrelin and growth hormone secretagogue receptor 1a (GHSR1a) gene with insulin resistance in obese female adolescents in Yogyakarta Special Region Cut Gina Inggriyani Rina Susilowati Madarina Julia
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 44, No 02 (2012)
Publisher : Journal of the Medical Sciences (Berkala Ilmu Kedokteran)

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Abstract

Previous study reported that among 79 obese female adolescents in Yogyakarta Special Region, 44 (55.7%) of them have insulin resistance. However, no significant differences on dietary habits and physical activity between the obese female who have insulin resistance and thosewho are insulin sensitive were observed. Therefore, it was thought that genetic factors are involved in the occurrence of insulin resistance. Ghrelin and growth hormone secretagogue receptor (GHSR) genes have been associated with the insulin signaling pathway with implicationsin insulin resistance. The study aimed to analyze the association between SNP (single nucleotid polymorphism) rs2922126 in GHSR1a gene with insulin resistance in obese female adolescents in Yogyakarta Special Region. Seventy eight obese female adolescents who were selected in theprevious study were involved in this study. Secondary data including name of subjects, age, body height, body weight, BMI (body mass index), fasting glucose level, fasting insulin level, waist circumference and HOMA-IR index were obtained from previous study. Polymerase Chai Reaction (PCR) and Restriction Fragment Length Polymorphism (RFLP) methods were used to the genotype analysis of SNP rs2922126. Chi-square test was used to calculate odds ratio on genotype and allele of SNP rs2922126 GHSR1a gene in insulin resistance and insulin sensitive groups. The results showed that A/A genotype individuals in SNP rs2922126 had higher risk to develop insulin resistance, compared to A/T and T/T genotypes individuals (OR: 2.03; 95%CI: 0.54-7.57). However, it was not significantly different (p>0.05). Individuals with A/A genotype and A allele carriers at SNP rs2922126 tended to have a higher value of BMI, fasting glucose level, fasting insulin level, HOMA-IR, and waist circumference compared to other carriers, althoughit was not significant (p>0.05). It can be concluded that SNP rs2922126 in GHSR1a gene is not associated with insulin resistance in obese female adolescents in Yogyakarta Special Region.Keywords: GHSR1a gene - SNP rs2922126 - insulin resistance - female - obese
Immunological diagnosis of nasopharyngeal carcinoma (NPC) by immunoperoxidase assay (IPA) method using and- VCA-EBV IgA Indrayani Purba Indrayani Purba
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 29, No 02 (1997)
Publisher : Journal of the Medical Sciences (Berkala Ilmu Kedokteran)

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Abstract

Nasopharyngeal Carcinomas (NPC) are the most frequent malignancy cases found at Ear, Nose and Throat (ENT) Department. Patients are commonly admitted in a severe condition. The success of therapy depends on the early detection of the disease. The most frequently NPC is WHO III type. WHO II and III types have close relationship to EBV. One of the methods to detect an early stage of the disease is by sero-immunology examination for anti VCA-EBV-IgA (VCA-IgA) using IPA method. The results of this VCA-IgA examination in this study were compared to the clinical examinations of NPC and biopsies to observe an analytical performance in terms of reproducibility, diagnostic performance and comparison test (significance and correlation tests). The VCA-IgA examination has been performed at the Department of Clinical Pathology, Dr. Sardjito General Hospital on 30 patients with clinical examination of NPC confirmed by biopsy, 30 normal subjects, 10 suspected KP patients, and 10 patients with positive ASTO. The results of this examination indicated that the reproducibility of VCA-IgA examination by IPA method is very good (Kappa = 81%). For diagnostic performance, a high sensitivity result is obtained (96%). There is no significant difference between the result of VCA-IgA examination with IPA method and NPC with clinical examination & biopsy (p > 0,05). It can be concluded that IgA anti VCA-EBV examination IPA method is useful in the early NPC diagnosis.Key Word : nasopharyngeal carsinoma - IgA anti VCA-EBV - immunoperoxidaseassay - analytic & diagnostic performance - reproducibility
Body Composition in Javanese Adult: Some Anthropometric Dimensions Related to Body Fat Janatin Hastuti
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 41, No 02 (2009)
Publisher : Journal of the Medical Sciences (Berkala Ilmu Kedokteran)

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Abstract

Background: Body composition is an integral component of entirely health and physical fitness. Measurement of fat component in assessing body composition is necessary on account of its relation to several health risks. Some anthropometric measurements such as waist to hip ratio (WHR), waist and hip circumferences, skinfold thickness, and sagittal abdominal diameter are demonstrated to be valuable for evaluating body composition, and further for identifying some health risk factors. Objectives: This study is addressed to know body composition and some anthropometric measurements related to percent body fat in Javanese adults living in Yogyakarta province. Methods: As many as 201 (98 males and 103 females) Javanese adults living in Yogyakarta province, aged 18 to 65 years were entrolled in this study. Measurements of body weight, height, waist, abdominal, and hip circumferences, sagittal abdominal diameter, and total skinfold thickness of triceps, biceps, subscapular, suprailiac were performed on the subjects. Body composition was assessed based on those measurements included percent body fat, body density, and skeletal muscle mass. Body mass index and waist-to-hip ratio were determined and categorized. The data then were analysed using independent Hest, Pearson correlation of product moment, linear regression, and chi-square test. Results: The result indicated that in a general sense, Javanese adults in Yogyakarta province had thin to medium body constitution and risk factor categorized of low to medium risk for males and medium to high risk for females. Javanese adult males were considerably heavier, taller, had greater means of body density, WHR, and muscle mass. By contrast, Javanese adult females were significantly higher in BMI, percentage of BF, and hip circumference. Statistically, there is no significant difference in total skinfold, abdominal circumference, and SAD, however, females indicated to a certain greater than the males. In the same manner, males had larger waist circumference. Conclusions: All of anthropometric dimensions including skinfold thickness, body density, waist circumference, abdominal circumference, WHR, sagittal abdominal diameter, and muscle mass are strongly correlated with body composition assessed with BMI and % BF. However, associations with BMI are fairly better than those of with percentage of BF. Among those measurements WHR showed the weakest correlation. There was also a different tendency in the power of correlation between anthropometric dimension with BMI and percentage of BF in males and females. Yet, all the measurements were supposed to be performed to incorporate evaluation on human body composition. Key words: body composition - Javanese adults - anthropometric measurements - percentage of body fat.
Anemia pada Wanita Hamil R. Soeprono R. Soeprono
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 20, No 04 (1988)
Publisher : Journal of the Medical Sciences (Berkala Ilmu Kedokteran)

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Abstract

Among complications affecting the pregnant woman, anemia is more frequently encountered than is usually realized, consequently becoming not infrequently overlooked in diagnosis, prognosis and therapy.Preexistent conditions as low socio-economic status, under or malnutrition, multiparity with short intervals, chronic occult bleeding or evident hemorrhages associated with previous deliveries or menstruation, are, with inadequate antenatal care, the most pertinent factors to deal with in terms of prevention and treatment. Since 95% of pregnancy anemias are iron deficiency anemias because of basically avoidable conditions, this specific iron deficiency problem deserves the most serious attention. Although of no marked consequence when of mild gradation, in moderate and severe cases all anemias of pregnancy — irrespective of etiology — tend to exert deleterious effects on the reproductive process, directly or indirectly.Key Words: anemia in pregnancy iron deficiency nutrition - pregnancy spacing -hematologic index
Beberapa hal tentang anatomi coitus pada manusia Adi Sukadana Adi Sukadana
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 9, No 04 (1977)
Publisher : Journal of the Medical Sciences (Berkala Ilmu Kedokteran)

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Abstract

keywords: pemahaman seks, anatomi fungsional, biologis

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