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Journal of the Medical Sciences (Berkala Ilmu Kedokteran)
Published by Universitas Gadjah Mada
ISSN : 01261312     EISSN : 23563931     DOI : http://dx.doi.org/10.19106/JMedSci005303202101
Core Subject : Science,
Immunology & microbiology Neuroscience
Journal of the Medical Sciences (JMedSci) or Berkala Ilmu Kedokteran (BIK) is an international, open-access, and double-blind peer-reviewed journal, published by Faculty of Medicine, Public Health and Nursing, Universitas Gadjah Mada Yogyakarta Indonesia. JMedSci aiming to communicate high-quality articles in the areas of biomedical science from basic to clinical sciences.The journal welcomes papers from original articles, case reports, reviews, and book reviews. All papers published in JMedSci are freely available as downloadable pdf files. The journal began its publication on March 1973 and published quarterly (January, April, July, and October). JMedSci is abstracted and indexed in DOAJ, Crossref, Google Scholar, Sinta, Indonesia One Search. JMedSci is accredited by Directorate of General Higher Education, the Ministry of Research, Technology, and Higher Education, Indonesia
Arjuna Subject : Kedokteran - Kedokteran (Lain-Lain)
Articles 2,170 Documents
 100   101   102   103   104 
Some physiological aspects of gastric ulcer Harjani Harjani
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 13, No 04 (1981)
Publisher : Journal of the Medical Sciences (Berkala Ilmu Kedokteran)

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Abstract

The key of the development of gastric ulcer is that the unionised substances or the lipid soluble substances which can cross the lipoprotein part or the cell membrane cause a rapid back diffusion of H-ions from the lumina I part of the stomach to the mucosa] layer, and a rapid Na-ions secretion. It causes cell damage and histamin release. Histamin causes mucosal edema and increases gastric acid secretion. Strong and repeated insults of histamin release may develop mucosal erosions and then ulcers.It is suggested that the development of gastric ulcer is promoted among others by acid hypersecretion, mucous hypersecrerion, delayed mucosal cell turn-over, SIgA deficiency, rnucosal exposure to mucosa] damaging substances, and prolonged and repeated mucosa] ischemia.The pain of gastric ulcer is probably due mainly to the action of acid or other irritants on a sensitive region of the mucous membrane.Key Words : gastric mucosal barrier - I-12 receptor - cephalic phase of gastric secretion - emotional stress - cigarette smoker
Ketela Pohon dan Toksisitasnya Siti Dawiesah Ismadi Siti Dawiesah Ismadi
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 7, No 02 (1975)
Publisher : Journal of the Medical Sciences (Berkala Ilmu Kedokteran)

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Abstract

key words: ketela pohon
Wary tuberculosis and cholestatic type hepatitis. A case report Edi Hartoyo Edi Hartoyo
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 34, No 02 (2002)
Publisher : Journal of the Medical Sciences (Berkala Ilmu Kedokteran)

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Abstract

Tuberculosis is still a major health problem in Indonesia. The organ commonly affected is lung (pulmonary tuberculosis) but other organs (extrapulmonary tuberculosis) may also be involved. Working diagnosis of tuberculosis in childhood is usually established by tuberculin test, chest x-ray and clinical manifestations, but it is often difficult to establish diagnosis of childhood tuberculosis as the chest x-ray and clinical manifestations are not always specific and we have difficulty in finding tuberculosis such as scoring method, bactec, serologic examination and biomolecular technic. However all of those examinations require further study for practical clinical use in the future. We report 12 year old child suffering from miliary tuberculosis and cholestatic type hepatitis. The recommended treatment for miliary tuberculosis is INH 10 mg/kgbw/day, Rifampicin 15 mg/kgbw/day, Ethambutol 15 mg/kgbw/day, Pyrazinamid 20 mg/ kgbw/day (for 2 months). Thereafter, the therapy was continued according to the conventional protocol. For the cholestatic type hepatitis we gave ursodeoxycolic (urdafalk) 8 mg/kgbw/day and cursil 2 x 1. The patient's condition improved after evaluation of 3 week therapy.Key words: miliary tuberculosis - diagnostic problem - cholestatic hepatitis - management
Prognosis Epilepsi Harsono Harsono
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 30, No 03 (1998)
Publisher : Journal of the Medical Sciences (Berkala Ilmu Kedokteran)

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Abstract

Prognosis is defined as the chance of recovery from a certain condition. Strictly, in epilepsy this means the chance of terminal remission once a patient has established a pattern of recurrent epileptic seizures. Questions concerning duration of treatment and long-term prognosis in childhood epilepsy are often raised by parents whose children are starting therapy with antiepileptic drugs. Many studies have focused on those issues and have examined the risk factors for poor prognosis as well as the risk of recurrence of seizures. The wide variation found in the risk of recurrence among those who have had a first seizure seems to be explained by differences In study design or differences in the characteristics of the study groups. In addition, the study of the prognosis of epilepsy has been confounded because of the fact that epilepsy is an expression of so many different underlying etiologies and syndromes.Prognosis of epilepsy should be informed clearly to the patients and/or parents. The clear information will improve the patient compliance in taking medication for a long time.Key Words : prognosis of epilepsy - remission - antiepileptic drugs - risk factors - recurrent epileptic seizures
Genetic syndromes associated with ocular anomalies Hartono Hartono
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 19, No 02 (1987)
Publisher : Journal of the Medical Sciences (Berkala Ilmu Kedokteran)

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Abstract

A syndrome is defined as the concurrence or running together of constant patterns of abnormal signs or symptoms. Syndromes can be either genetic or non-genetic in origins. Genetic diseases consist of genic diseases, chromosomic diseases and embryopathies. Genetic syndromes also consist of genic disease syndromes, chromosomic disease syndromes and embryopathic syndromes. Syndromes of genic diseases are caused by pleiotropic mutation of the genes which give rise to multiple (pleiotropic) effects. Syndromes of chromosomic diseases are caused by chromosomal derangement either by the abnormalities of their structure or their number. There are many genetic syndromes associated with ocular anomalies. Geeraets has collected 436 ocular syndromes either genetic and non-genetic in origins, and 49 of 135 recognizable human malformations collected by Smith are also associated with ocular defects. Some important chromosomic syndromes such as tkisomy 21, Patau, Edward, and cri-du-chat syndromes are also associated with ocular anomalies. Key Words: genetic diseases - pleiotropic effects - ocular anomalies - chromosomic syndromes - embryopathies
Teknologi Pada Pendidikan Kedokteran Di Indonesia M. Ismadi M. Ismadi
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 12, No 04 (1980)
Publisher : Journal of the Medical Sciences (Berkala Ilmu Kedokteran)

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Abstract

Keyword : Teknologi Pendidikan Kedokteran
Comparative study of the endocrine functions in Norplant vs Depoprovera acceptors Mochamad Anwar Mochamad Anwar
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 26, No 02 (1994)
Publisher : Journal of the Medical Sciences (Berkala Ilmu Kedokteran)

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Abstract

The steroidal contraceptive agents are highly predictable in preventing pregnancy, however, all currently used synthetic progestogens have certain potential side effects. These side effects may be due to either the direct actions of the synthetic steroids or the indirect actions through the women's own endocrine system.The objective of the study is to evaluate potential alterations of the endocrine functions in women using Norplant compared to injectable contraceptive method.The study was conducted in a cohort study by recruiting 25 women in each group receiving either Norplant or Depoprovera contraceptive method voluntarily. Six months after entering the study 10 ml of blood was taken from the cubits] vein and follicle stimulating hormone (FSH) , luteini zing hormone (LH), prolactine (PRL), progesterone (P), oestradiol (E2), total testosterone (r), free testosterone (FT) and sex hormone binding globulin (SHBG) were measured using radioimmunoassay.The mean of SHBG level in Norplant (29.44 ± 9.85 nmol/l) is statistically, lower (p421.001) compared to Depoprovera acceptors (50.64 ± 21.29 nmol/l), however, they were still in the normal range. The means of total testosterone and free testosterone level were higher in Norplant group, however, they were not statistically different (p = 0,391 and 0.182 respectively). No androgenicity symptoms were clinically found in both groups. Either Norplant or Depoprovera lowering the secretion of progestogen and oestrogen, indicated that the alterations of endocrine function occured more frequently in the level of target organ (ovary) rather than in the level of hypophysis or hypothalamus. These findings were also confirmed by the mean levels of FSH, LH and prolactine which were also in the normal range.It is concluded, that there were no potential alterations of the endocrine functions in women using either Norplant or Deprovera especially in androgenicity. The influence of both progestogen contraceptive methods were greater on the level of target organ.Key words : contraception-Norplant-Depoprovera -radioimmuno assay-blood
Targeted phototherapy for skin diseases Sa’adatul Huriyah Arief Budiyanto
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 44, No 01 (2012)
Publisher : Journal of the Medical Sciences (Berkala Ilmu Kedokteran)

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Abstract

Phototherapy is a therapeutic strategy in dermatology for treating several skin diseases.Conventional phototherapy has some disadvantages, hence a targeted phototherapy that emitsselective laser or ultraviolet (UV) light and targets specific area of affacted skin has been developed.Targeted phototherapy is considered to be more aggressive and has higher efficacy. Severaltargeted phototherapy devices emit one or several types of light. The use of targeted phototherapyhas been studied in vitiligo, psoriasis, eczema, keloid, hypopigmented scar or striae alba, andoral lichen planus.
Erythroleukemia J.S. Mick J.S. Mick
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 5, No 04 (1973)
Publisher : Journal of the Medical Sciences (Berkala Ilmu Kedokteran)

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Abstract

keywords: acuta erythremic myelosis, morbus Di Guglielmo, leukimia
The new concepts in basic oncology research Soeripto Soeripto
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 25, No 03 (1993)
Publisher : Journal of the Medical Sciences (Berkala Ilmu Kedokteran)

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Abstract

Research on epidemiology, pathology, clinical course, and treatment of cancer is available. The epidemiological and clinical research on cancer must be brought into a comprehensive scheme. Basic research on oncology is suggested to be based on cancer epidemiology, and applicable for clinical practice. This article discusses the new concept of basic oncology research using breast cancer as a model.It is concluded that the new concepts in basic oncology research have to be based on the community need. It will be better if the research is multidisciplinary and multiinstitutional approach. Using this approach the expectation is that and the result could solve the problem either in the community or in the hospital.Key Words: oncology-cancer epidemiology-breast cancer oncogen-immunohistoclinical signs -prognostic index

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