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Journal of the Medical Sciences (Berkala Ilmu Kedokteran)
Published by Universitas Gadjah Mada
ISSN : 01261312     EISSN : 23563931     DOI : http://dx.doi.org/10.19106/JMedSci005303202101
Core Subject : Science,
Immunology & microbiology Neuroscience
Journal of the Medical Sciences (JMedSci) or Berkala Ilmu Kedokteran (BIK) is an international, open-access, and double-blind peer-reviewed journal, published by Faculty of Medicine, Public Health and Nursing, Universitas Gadjah Mada Yogyakarta Indonesia. JMedSci aiming to communicate high-quality articles in the areas of biomedical science from basic to clinical sciences.The journal welcomes papers from original articles, case reports, reviews, and book reviews. All papers published in JMedSci are freely available as downloadable pdf files. The journal began its publication on March 1973 and published quarterly (January, April, July, and October). JMedSci is abstracted and indexed in DOAJ, Crossref, Google Scholar, Sinta, Indonesia One Search. JMedSci is accredited by Directorate of General Higher Education, the Ministry of Research, Technology, and Higher Education, Indonesia
Arjuna Subject : Kedokteran - Kedokteran (Lain-Lain)
Articles 2,170 Documents
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The relationship between vitamin A and ferritin towards malondialdehyde level among Javanese male smokers Ajeng Viska Icanervilia; . Sunarti; Ahmad Hamim Sadewa
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 44, No 01 (2012)
Publisher : Journal of the Medical Sciences (Berkala Ilmu Kedokteran)

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Abstract

Cigarette smokes produce a large number of oxidants and promote secretion of ferritin byalveolar macrophages which are potential to encourage the lipid peroxidation. Malondialdehyde(MDA) is used as a parameter of lipid peroxidation. The study was aimed to evaluate therelationship between blood level of vitamin A and ferritin and MDA among Javanese malesmokers. Sixty men who lived in Purworejo District, Central Java, Indonesia comprising 30smokers as case group and 30 nonsmokers as control group were involved in this study. Bloodsample was obtained from cubiti vein and then centrifuged to obtain plasma or serum. Blood levelsof vitamin A, ferritin and MDA were measured by HPLC, ELISA and spectrophotometric methods,respectively. The result showed that the blood vitamin A, ferritin, and MDA levels in smokers were25.09±9.51μg/dL, 35.50±24.17ng/dL, 1.15±0.42μg/L, respectively, whereas in non smokers, theywere 26.11±9.19 μg/dL, 38.60±15.25 ng/dL, 1.06±0.50 μg/L, respectively. Therewas no significantdifference of the blood vitamin A, ferritin, and MDA levels between smokers and the non smokers(p>0.05). The linear regression analysis indicated that there was negative relationship betweenblood vitamin A and MDA levels although it was not significant (p=0.052), while blood ferritin andMDA levels had a significantly positive relationship (p=0.010). In conclusion, the low level of bloodvitamin A among cigarette smokers does not lead to high blood MDA level, while high level of bloodferritin among smokers leads to high blood MDA level. 
Hari Perhitungan Lahir Dan Hari Lahir Zain Alkaff Zain Alkaff
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 6, No 01 (1974)
Publisher : Journal of the Medical Sciences (Berkala Ilmu Kedokteran)

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Abstract

Ditinjau 1485 kasus persalinan dengan berat lahir anak 2500 g atau lebih, mengenai hubungan antara Hari Lahir (HL) dengan Hari Perhitungan Lahir (HPL) yang diperhitungkan dengan rumus Naegele dari Hari Pertama Menstruasi Terakhir (HPM). .Kasus-kasus dibagi dalam kelompok-kelompok dengan cyclus Menstruasi dan paritas tertentu dan dicari hubungan antara kedua hal tersebUt dengan lamanya kehamilan.
Cytologic examination of the thoracocenthesis fluid for the diagnosis of a malignant mesothelioma and adenocarcinoma. A comparative diagnosis. Ahmad Ghozali Ahmad Ghozali
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 25, No 03 (1993)
Publisher : Journal of the Medical Sciences (Berkala Ilmu Kedokteran)

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Abstract

Reccurent pleural effusions are frequently the first manifestation of a diffuse malignant pleural mesothelioma. Pleural effusion of the malignant mesothelioma is frequently indistinguishable from the pleural effusion due to adenocarcinoma. The prognosis of this tumor is poor, but immediate and accurate therapy will render prolonged remission. For these reasons, microscopic examination of thoracocenthesis fluid is necessary, because it may provide an immediate diagnosis.Unfortunately, the reliability of cytologic diagnosis is still disputable. Based on microscopic examination, there is no single pathognomonic feature. The cytologic diagnosis of a malignant pleural examination is based on the constellation of findings. The history of the course of the disease, optimal sample preparation, and special stains are important requirements to provide definitive diagnosis.Key Words: mesothelioma adenocarcinoma thoracocenthesis fluid air-dried May Grunwald - Giemsa monoclonal antibody B72.3
Histoplasmosis prevalence among medical students of the faculty of Medicine Islamic University of North Sumatera and the association between pet animal and histoplasmin test. Azhar Tanjung Azhar Tanjung
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 29, No 03 (1997)
Publisher : Journal of the Medical Sciences (Berkala Ilmu Kedokteran)

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Abstract

A cross sectional study was conducted at the Faculty of Medicine, Islamic University of North Sumatera (FK MU) Medan with the population of 169 medical students. It was found that the prevalence of histoplasmosis was 13.61% and there was no correlation between the gender with the histoplasmin test reactivity. The most precipitating factor of the prevalence for the positive histoplasmin test was pet animal. The other precipitating factors were found such as in bat, cave adventure and contact with wood environment. There was significant association between pet animal and the reactivity of histoplasmin test. In conclusion, the prevalence of histoplasmosis with moderate category is found in the young adult population group. The pet animal has significant possibility as the precipitating factors and its role is needed for further attention.Key words : histoplasmosis - histoplasmin test - prevalence - young adult - pet animal.
The effect of operating room design and behavior of operating room staff on surgical site infection (881) incidence Yulianto Widodo;, Iwan Dwiprahasto
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 41, No 04 (2009)
Publisher : Journal of the Medical Sciences (Berkala Ilmu Kedokteran)

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Abstract

Introduction: In surgery, medical error is often related to surgical site infection (551).Santa Maria Hospital, Pemalang, is a private hospital which gives priority to quality and applies the patient safety principle. During 2006, there were 7 cases of 551 in 785 surgical cases in Santa Maria Hospital, Pemalang, but this number was considered as the tip of an iceberg. The high microorganism rate, operating room design which was not agreeable with the standard by Kepmenkes No 1204/MENKES/SK/X/2004, and the behavior of operating room staff were the risk factors of 55!. ObJective:To find out the effect of the change in operating room design and behavior of operating room staff on 551 incidence in Santa Maria, Pemalang, and to find out the risk factors of 55!. Method: It was a quasi-experimental study with pre- and post-test without control group design. Population were all operating room staff, while subject of this study was operating room design. Dependent variable was 551incidence, while independent variables were behavior of operating staff and operating room design. Data were analyzed with independent t-test, chi-square test, and multivariate logistic regression. Re.ult: The change in operating room design and operating room staff behavior has significantly decreased the incidence of 551 (OR = 3.646; 95%CI = 1.24 < OR< 10.77). Conclu.lon: Intervention on operating room design and staff behavior has decreased the incidence of 55!. Risk factors of 551were operating room design, operating room staff behavior, and duration of surgery.
Oxidative and nitrosative stres in some risk factor of stroke Hasyim Fachir Hasyim Fachir
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 37, No 02 (2005)
Publisher : Journal of the Medical Sciences (Berkala Ilmu Kedokteran)

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Abstract

Stroke is a disease caused by cerebral blood flow disturbance. Disturbance of cerebral blood flow could induce oxidative and nitrosative stres. Beside that, stroke is a also neurodegenerative disease that based on several risk factors. Some risk factors of stroke have causative link with oxidative and nitrosative stres. These risk factors include aging, hypertension, smoking, atherosclerosis and diabetes mellitus. Key words: stroke - risk factor -reactive oxygen species - reactive nitrogen species
The relationship of asthma with physical fitness of Junior High School students in Yogyakarta. Isri Muninggar Isri Muninggar
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 34, No 02 (2002)
Publisher : Journal of the Medical Sciences (Berkala Ilmu Kedokteran)

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Abstract

Background: The understanding on asthma and the patient's daily quality of life remain an issue which still need to be elucidated. Information about the relationship between asthma and physical fitness is an important factor that has to be considered in the management of asthma patients.Objective: To examine the relationship between asthma and the physical activity and physical fitness, with regards to the factors influencing them, in junior high students in Yogyakarta.Research design: crosss sectional.Materials and Methods: The samples were part of a main research project on the prevalence of asthma in the population of junior high school students in Yogyakarta. The incidence of asthma was determined using a previously validated modified questionnaire from ISAAC, ATS 78 and Robertson. Cases were students diagnosed as asthma, and the controls were students without asthma. Cases and controls were matched for age, sex, and school year. The basic characteristics of the students and parents, daily circle activities, history of smoking, school grade and physical exercise, the time needed to run a 100 meters distance were obtained using a quesionnaire. Lung function tests were done before and after 10 minutes static bicycle exercise. Data are analyzed using student T-test and X2 test.Results: There were 219 students who fulfilled the inclusion criteria, consisted of 102 males (46.57%) and 117 females (53.43%). The case group (asthma) comprised 119 students while 100 students were the control group. There is no statistically significant difference between the average age of subjects in the case group (14.70 years) with the control group (14.62 years) (p=0.416). There were no statistically significant differences between the cases and controls concerning the school grade and physical exercise (p=0.243), the time needed to run 100 meters distance (p=0.959), daily activities, physical activities: athletic (p=0.511), game playing sport (p =0.342), bicycling (p =0.212), swimming (p=0.586), the ability to joint to physical activities/physical exercise. We also could not find statistically significant differences in the lung function test before: VC p=0.271, FVC p =0.694, FEV1 p=0.995, FEV1/FEC p=0.579, PEF 25% p=0.144, PEF 25-75% p=0.179, MVV p=0.340 and Ex. Time p=0.100, and after exercise using static bicycle for 10 minutes VC p=0.347, FVC p=0.805, FEV1 p=0.767, FEV1/FEC p=0.401, PEF 25% p=0.152, PEF 25-75% p=0.210, MVV p =0.310.Conclusion: There is no statistically significant difference in daily physical activities and school physical exercise activity between students in the asthmatic group and control group.Key words: Asthma physical fitness - physical activity - incidence of smoking - nutritional status - growth and development - lung function test
Incidence hepatitis infectiosa di bagian ilmu kesehatan anak rumah sakit Universitas Gadjah Mada Tonny Sadjimin Tonny Sadjimin
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 5, No 01 (1973)
Publisher : Journal of the Medical Sciences (Berkala Ilmu Kedokteran)

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Abstract

Keywords: penyakit menular, hepatitis, hepatotropic, filterable
The involvement of mesolimbic dopaminergic system in ovulation in rat (Rattus norvegicus) Soedjono Aswin Soedjono Aswin
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 25, No 01 (1993)
Publisher : Journal of the Medical Sciences (Berkala Ilmu Kedokteran)

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Abstract

Mesolimbic dopaminergic system involvement in the ovulatory process was studied in the immature su'perovulation rats (Rartus norvegicus). Nucleus ventralis tegmenti (NVT, area A-10) was neurochemically lesioned by stereotaxically placed injection of I Vg 6-hydroxydopamine (6-OHDA) into the brain. Ovarian weight, frequency and rate of ovulation, the number of corpora lutea found in the ovaries, and histologic features of the ovaries were observed.The results of the present experimental study indicate that neurochemical lesion of NVT with 6-OHDA produced a significant (p<0.01) decrease in the ovarian weight, as well as the ovulation rate and the number of corpora lutea found in the ovaries, compared to the shank-operated control and normal control groups. The frequency of ovulation, however, was not affected; it means that all groups of immature rats underwent ovulation. It is interesting to note that the ovulation rate of the lesioned group was suppressed (but not prevented) by about 60% as shown by the decrease in the number of corpora lutea found in the ovaries and in the number of ova per ovulation. Histologic features of the ovaries of the lesioned group performed an inhibition of follicular development as evidenced by the characteristic :features of the induction of polycystic degeneration, beside the decrease in the number of corpora lutea found in the ovaries.It is concluded that mesolimbic dopaminergic system specifically plays a significant role in the regulation of ovulatory process in the immature superovulation rats. Based on the present data it is hypothesized, that lesioning mesolimbic dopaminergic system chemically with 6-OHDA resulted in significant decrease in luteinizing hormone releasing hormone (LHRH) released from hypothalamus, which in turn ensued the decrease in the tonic release of luteinizing hormone (LH), which is known responsible for the development of the ovarian follicles; but it seems that there is a slight suppression in the pulsatile release of LH, which is responsible for the initiation of ovulation.Key Words: nucleus ventralis tegmenti - mesolimbic dopaminergic systenm - 6-hydronydopanine -    ovulation - Rattus riorvegicus
Comparison between vitamin E plasma level in diabetic retinopathy and normal person Tri Wahyu Widayanti Tri Wahyu Widayanti
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 29, No 01 (1997)
Publisher : Journal of the Medical Sciences (Berkala Ilmu Kedokteran)

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Abstract

Diabetic retinopathy is one of the late complications of diabetes mellitus. Recent data have suggested that free radicals possibly play a role in its pathophysiology. Oxidative stress is very high in hyperglycemic condition leading to increased lipid peroxidation of the phospholipid cell membrane. Vitamin E is a chain breaking membrane antioxidant which can prevent lipid peroxidation in the cell membrane. The study was aimed at determining vitamin E plasma level in diabetic retinopathy compared to healthy subjects. In this study vitamin E plasma level in 30 diabetic retinopathy patients and 30 healthy subjects were measured by using (HPLC) technique. The result showed that the mean of vitamin E plasma level in healthy subjects and patients with diabetic retinopathy are 5.09 ± 3.51 and 4.32 ± 2.75 µg/ml respectively (Student t-test, p > 0.05) Total lipid level has a significant influence in increasing the vitamin E plasma level with coefficient correlation r=0.9746 and p<0.01. Further studies are needed to clasify factors that influence vitamin E plasma levels.Keywords: vitamin E - diabetic retinopathy - oxidative stress - lipid peroxidation

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