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Journal of the Medical Sciences (Berkala Ilmu Kedokteran)
Published by Universitas Gadjah Mada
ISSN : 01261312     EISSN : 23563931     DOI : http://dx.doi.org/10.19106/JMedSci005303202101
Core Subject : Science,
Immunology & microbiology Neuroscience
Journal of the Medical Sciences (JMedSci) or Berkala Ilmu Kedokteran (BIK) is an international, open-access, and double-blind peer-reviewed journal, published by Faculty of Medicine, Public Health and Nursing, Universitas Gadjah Mada Yogyakarta Indonesia. JMedSci aiming to communicate high-quality articles in the areas of biomedical science from basic to clinical sciences.The journal welcomes papers from original articles, case reports, reviews, and book reviews. All papers published in JMedSci are freely available as downloadable pdf files. The journal began its publication on March 1973 and published quarterly (January, April, July, and October). JMedSci is abstracted and indexed in DOAJ, Crossref, Google Scholar, Sinta, Indonesia One Search. JMedSci is accredited by Directorate of General Higher Education, the Ministry of Research, Technology, and Higher Education, Indonesia
Arjuna Subject : Kedokteran - Kedokteran (Lain-Lain)
Articles 2,170 Documents
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Beberapa pokok persoalan tentang hubungan antara. Ras dan penyakit di Indonesia T. Jacob T. Jacob
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 10, No 02 (1978)
Publisher : Journal of the Medical Sciences (Berkala Ilmu Kedokteran)

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Abstract

Keyword : Hubungan ras dan penyakit
Differentiation and identification of Aedes albopictus Skuse from several population in Indonesia based on genetic polymorphisms Budi Mulyaningsih Budi Mulyaningsih
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 36, No 1 (2004)
Publisher : Journal of the Medical Sciences (Berkala Ilmu Kedokteran)

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Abstract

Background: Aedes albopictus play important role in the spread dengue virus, it is spread widely in Indonesia. Geographical condition of Indonesia which shows varying climatology, biogeography and environmental factors seem to be very possible to cause the difference in the genetic structure of Ae. albopictus.Objective: The aim of this study is to determine the genetic polymorphism of each Ae. albopictus population.Methods: Genomic DNA was extracted from individual mosquitoes from 4 geographic populations of Ae, albopictus and amplified in PCR reactions using single primers of arbitrary nucleotide sequence.Result: The DNA polymorphism level of Ae. albopictus population originated from Yogyakarta is 80.77%, followed by population originated from Padang is 57.14%, Banjar is 40.74% and Timika is 37.50%. Conclusion: The genetic structure of the Ae. albopictus populations shows obvious differences, and they shows that they are from different group and separated with the various difference percentage.Key words: genetic polymorphism - population - Ae. albopictus - dengue virus - RAPD-PCR.
Fever in children: palpation, the understanding of mother and further • action Purwoko Purwoko
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 35, No 2 (2003)
Publisher : Journal of the Medical Sciences (Berkala Ilmu Kedokteran)

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Abstract

Background: Fever is the most common event lead the mother to bring her children to seek for health service. Assessment of fever by palpation is commonly done to recognize fever in children. Objective: The aim of this study was to examine the sensitivity of palpation and understanding of fever in children by mothers.Methods: This study was descriptive analytic design, done to mothers visited outpatient clinic Department of Child Health Dr. Sardjito Hospital from Januari until April 2001. Sample for study determined by systematic random sampling. Data were obtained by interview with the mothers using questionnaires and temperature measurements to children using thermometer. Data were analysed using Chi-square (c2), and logistic regression.Results: Most of (91%) all mothers (511) assessed fever in children by palpation and 23,1% used thermometer. Palpation by mothers had showed that 84.6% of mothers palpated fever rightly and 77.2% of mothers palpated non fever rightly. Most of (95.7%) mothers felt worried when their children got fever, with the reasons afraid of seizure (26.2%), or when they suffered from severe illness (64.0%). Mothers who understood about the definition of fever (> 37.50C) were more worried (OR: 3.80 (95% CI: 1.36-10.61%1} than they didn't. The first practice to manage fever in the family was giving antipyretic (72.0%). Antipyretics administration was based on consideration of antipyretic benefit (OR: 2.31 (95% CI: 1.51-3.54%)), and the availability of antipyretic in household (OR: 2.14 (95% CI: 1.423.23%1}, but wasn't on mother's worrying (OR: .394 (95% CI: .12-1.35)).Conclusions: Palpation assess fever by mothers.The higher the understanding of mothers on fever the sooner they seek for help. Mothers understanding on the benefit of antipyretics and the availability of antipyretics at home make the mothers giving antipyretics sooner.Key words: fever-accuracy of fever-mother's knowledge-mother's attitude-antypyretics administration
Dosen Abad XX1 Anonim Anonim
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 24, No 02 (1992)
Publisher : Journal of the Medical Sciences (Berkala Ilmu Kedokteran)

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Abstract

Kata Kunci: Pendidikan Tinggi - Dosen
Positive effect of magnetism on cerebral malaria (A hypothesis) Sugeng Juwono Mardihusodo Sugeng Juwono Mardihusodo
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 28, No 03 (1996)
Publisher : Journal of the Medical Sciences (Berkala Ilmu Kedokteran)

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Abstract

Cerebral malaria (CM) is one of serious complications of falciparum malaria that may cause high mortality rate in a malaria endemic area where Plasmodium falciparum is predominant. Based on a lot of histopathological findings, pathogenesis of CM is thought to be mainly caused by the blockade of cerebral vessels by parasitized red blood cells (PRBC), that could be aggravated by secondary factors such as depositions of immune complexes in brain capillaries, reduced humoral or cell-mediated immune responses, action of endotoxin, and the action of tumor necrosis factor (TNF). Biological effects of magnetism have been extensively and intensively studied in the past five decades including their applications to the treatment of common diseases. Among other conclusions reached by scientists after innumerable experimentations in the field of biomagnetism are (1) living systems are very sensitive to magnetic fields and magnetic effect reaches every cells in the body on account of the highly pervasive character of magnetism; (2) as the entire body is infused with electrical energy and magnetic fields exist in every part of it, magnets, if properly applied exercise a positive effect on the electrical response behaviour pattern; (3) effects on the blood picture and on erythrocyte sedimentation rate result, from exposure of the organism to a constant magnetic field which initiate biochemical changes; (4) a magnetic field can exert direct influence on the diencephalon and the forebrain. Studies on the effect of magnetism on blood revealed the activation of the iron content in the blood and a weak current was discerned to have been generated, the process of ionisation was hastened which freed the blood from danger of clotting and stimulated easier and more spontaneous flow of blood through the blood vessels and capillaries. It is hypothesized, therefore, that magnetism exerts a positive effect on CM.Key Words : magnetotherapy - biomagnetism - biomagnetics - malaria - biomagnetology
Hantavirus infection in clinically suspected dengue fever patients Praseno Hera Nirwati
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 40, No 03 (2008)
Publisher : Journal of the Medical Sciences (Berkala Ilmu Kedokteran)

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Abstract

Background: Hantavirus has been found in many parts of the world, including newly isolated virus in Indonesia. Although infection with the virus can result in specific signs and symptoms known as hemorrhagic fever with renal syndrome (HFRS), clinical presentation of the disease may be similar to those of dengue or other viruses infection. Diagnosis of both dengue and hantavirus infection should be established by laboratory test for the detection of specific antibodies.Objective: The aim of this study was to determine the presence of hantavirus infection in patients suspected to have dengue fever.Methods: Sera were prepared from venous blood of patients. Specific IgG and IgM anti hantavirus in sera from clinically suspected dengue fever patients were examined by an indirect immunoflourescence antibody technique.Results: Eight percent of sera samples were positive for both specific IgG and IgM anti hantavirus, whereas 1 2 percent of samples were positive for IgG only.Conclusion: It is concluded that the recent infection with hantavirus have been found in 8 percent of clinically suspected dengue fever patients, whereas 12 percent of the patients were infected with the virus some time in the past.Key words: hantavirus - immunofluorescence antibody technique - dengue fever - specific IgG and IgM anti hantavirus
Tegralogy of Fallot: Pro-and post-surgical case study A. Samik Wahab A. Samik Wahab
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 21, No 04 (1989)
Publisher : Journal of the Medical Sciences (Berkala Ilmu Kedokteran)

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Abstract

Defects in the ventricular septum with obstruction to right ventricular outflow encompass a wide anatomic, physiologic and clinical spectrum. Large ventricular septal defects occur with pulmonic stenosis that varies from mild to severe to complete (pulmonary atresia). Small ventricular septal defects occur with mild to severe pulmonic stenosis. The most familiar and prevalent combination is tetralogy of Fallot with the incidence of approximately 0.4 to 0.6 per 1000 live births.The following illustrates four cases of Fallot's tetralogy with a wide anatomic, physiologic and clinical variations. The first case is a small ventricular septa' defect along with severe pulmonic stenosis, the fourth case, however, comprises a large VSD and pulmonary atresia, while in the others the anatomic variations are in between.Hypoxic spells are important aspects of the history in Fallot's tetralogy. Spells are an alarming episode that should be treated as an emergency. Knee-chest position, squatting or sitting with legs drawn underneath can afford to relief dyspnea.The best treatment, however, is surgical treatment, indicated in all patients with Fallot's tetralogy. The result of this surgical treatment up to now is very satisfactory.Key Wards: tetralogy of Fallot - pulmonic stenosis - ventricular septal defect - pulmonary atresia - bicuspid a pulmonalis
DEVELOPING COURSES IN THE BEHAVIOURAL AND SOCIAL SCIENCES FOR MEDICAL STUDENTS: NEW PROSPECTS FOR AN OLD PROBLEM Peter J.Blizard Peter J.Blizard
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 8, No 04 (1976)
Publisher : Journal of the Medical Sciences (Berkala Ilmu Kedokteran)

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This paper described methods which can be used to construct "behavioural objectives" at the level of a Department of Social and Behavioural Sciences within a Faculty of Medicine, and also in the choice of Specific curricular content. An attempt is then made to(i) Identify the basic skills that studies in the social and behavioural science might seek to develop in medical students ;(ii) Develop a set of Departmental Objectives which arise out of these basic skills, so that courses in these areas are as realistic and as practical as possible ;(iii) Extend this approach and show how it might be used as a method for developing a specific and measurable curriculum in the social and behavioural sciences ;. (iv), Identify some basic practical problems arising from a decision, by a Faculty of Medicine, to incorporate aspects of the social and behavioural sciences into the curriculum.For illustrative purposes each of the above tasks has been applied to the Indonesian context. It may thus be expected to have direct practical application to nther, similar developing countries ; but, of course, the approach to curriculum design will have more widespread application.
Profile of patients diagnosed as sepsis (ICD X: A41.9) in the Internal Medicine Ward Sardjito Hospital in 2002 Yanri Wijayanti Subroto Yanri Wijayanti Subroto
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 35, No 4 (2003)
Publisher : Journal of the Medical Sciences (Berkala Ilmu Kedokteran)

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Abstract

Background: Sardjito Hospital as the top referral hospital for the Yogyakarta Special Province and the southern part of Central Java has a mortality rate of 56.83% of patients diagnosed as sepsis (ICD X A41.9). The overall hospital sepsis case in the year 2002 was 275, with 50.54% (139) of which was treated in the Internal Medicine ward. Out of the 139 cases, 44.60% was man and 55.40% was woman. Method: This study was focused on the identification of demographic and clinical factors of patients diagnosed as sepsis (ICD X A41.9) in Internal. Medicine ward Sardjito Hospital in 2002. Demographic data include sex, age, system of hospital admission (referral or self admition. Clinical data include the concomitant disease(s), causes of death, and type of cultured microorganism(s). The identification of these factors may be beneficial for designing an early warning system for fatal cases of patients with sepsisResults: Only 120 (86.33%) out of 139 medical records were eligible for further analysis. Seventy-one (59.17%) patients died in the hospital, whereas 49 (40.83%) were discharged from the hospital, but mostly were forced leave (only 6 patients were discharged in a good condition). The median ± SD age was 53.5 ± 15.99 years old with the youngest age was 17 and the oldest was 98. More than 50% of patients were above 50 years old. As many as 72 (60%) patients were admitted to the hospital referred by other hospitals (a few numbers were referred by private physicians), and only 48 (40%) patients were self-admitted. The average length of hospitalization was 6.96 ± 5.43 days, with the range of 1-25 days. The cause of death of these patients were mostly septic shock (61.97%), followed by respiratory failure (19.72%), intracranial process (14%), cardiac arrest (2.8%) and MOFS (1.4%). The underlying/concomitant diseases are:. gastrohepatology (mostly hepatic cirrhosis and hepatocellular carcinoma); hematology (acute leukemia, multiple myeloma), pulmonology (TB, COPD, pneumonia), oncology (Ca mammae, Ca cervix); endocrinology (DM type 2 with ulcus diabeticum), nephrology (chronic renal failure), cardiology (congestive heart failure), obsgyn (septic puerpuralis) and trop-med (urinary tract infection, malaria), etc.Conclusion: We report here research on medical record of patients diagnosed as sepsis (ICD X: A41.9) in Internal Medicine ward Dr. Sardjito Hospital in 2002. There were 139 cases with only 120 were eligible for analysis. Mortality reached 59.17% of cases with median of age 53.5 years and average length of hospitalization of 6.96 days. The most common cause of death was septic shock and gastrohepatology as the most common comorbid disease.Key words: sepsis-demographic-clinical presentation-cause of death
Diagnostic value of pyroninophilic lymphocyte in dengue haemorrhage fever in children Setya Wandita Setya Wandita
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 31, No 04 (1999)
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Abstract

Background: Dengue hemorrhagic fever (DHF) is still a problem in Indonesia. Early diagnosis is important in the management. The cytoplasm of activated lymphocytes in dengue infection contains ribonucleic acid (RNA). RNA can be specifically shown by pyronin staining.Objective: To know the diagnostic value of lymphocyte pyroninophilic in DHF in children.Methods: Subjects were patients hospitalized in the Pediatric Department of Faculty of Medicine/Pediatric Ward Sardjito General Hospital, from September 1995 to December 1996, with 2-7 days of fever, positive tourniquet test, and 0-14 years of age. Clinical diagnosis of DHF was based on WHO 1986 criteria. Hemagglutination inhibition (HI) test and/or antibody antidengue were used to confirm the diagnosis of DHF. Peripheral blood smear was stained with pyronin stain according to Sutaryo modification. Lymphocyte percentage was counted per 100 leukocyte under light microscope.Results: Means of pyroninophilic lymphocyte numbers were increased from day-3 to day-5 of fever and then decreased. There were significant difference between the means in non-dengue infection and in dengue infection from day-3 to day-7 of fever, between dengue fever (DF) and DHF from day-3 to day-6 of fever, and between non shock (DHF-I and DHF-II) and shock cases (DHF-III and DHF-IV) from day-3 to day-9 of fever. The number of pyroninophilic lymphocytes correlated with the degree of DHF. Using cut-off point of 4 at day-5 of fever, the sensitivity was 86,2%, specificity was 84,3%, positiv predictive value was 92,6%, and negative predictive value was 65,1%.Conclusion: Pyroninophilic lymphocyte has a high diagnostic value in DHF in children.Key words: Dengue hemorrhage fever - ribonucleic acid - pyroninophilic lymphocyte - diagnosis

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