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Journal of the Medical Sciences (Berkala Ilmu Kedokteran)
Published by Universitas Gadjah Mada
ISSN : 01261312     EISSN : 23563931     DOI : http://dx.doi.org/10.19106/JMedSci005303202101
Core Subject : Science,
Immunology & microbiology Neuroscience
Journal of the Medical Sciences (JMedSci) or Berkala Ilmu Kedokteran (BIK) is an international, open-access, and double-blind peer-reviewed journal, published by Faculty of Medicine, Public Health and Nursing, Universitas Gadjah Mada Yogyakarta Indonesia. JMedSci aiming to communicate high-quality articles in the areas of biomedical science from basic to clinical sciences.The journal welcomes papers from original articles, case reports, reviews, and book reviews. All papers published in JMedSci are freely available as downloadable pdf files. The journal began its publication on March 1973 and published quarterly (January, April, July, and October). JMedSci is abstracted and indexed in DOAJ, Crossref, Google Scholar, Sinta, Indonesia One Search. JMedSci is accredited by Directorate of General Higher Education, the Ministry of Research, Technology, and Higher Education, Indonesia
Arjuna Subject : Kedokteran - Kedokteran (Lain-Lain)
Articles 2,170 Documents
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Polytherapy in the management of epilepsy Samekto Wibowo Samekto Wibowo
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 29, No 04 (1997)
Publisher : Journal of the Medical Sciences (Berkala Ilmu Kedokteran)

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Abstract

Antiepileptic drugs take a dominant role in the management of epilepsy. Although monotherapy has been recommended, polytherapy sometimes is very difficult to be avoided. This study wanted to remind: what factors should be considered in epilepsy polytherapy. Drug-drug interactions and the risk of side effects might occures. Optimal polytherapy was often achieved with drugs that had different mechanism of action, relatively few side effects, high therapeutic indexes, and limited or no drug interactions. To choose the drug groups, the following factors should also be considered, namely: efficacy, safety, suitability and cost of treatment. In short, polytherapy should be rational.Key words: epilepsy - monotherapy - polytherapy - rational use of drugs - drugs infraction
The risk factor of urinarytract infection in patient with leukemia Melati Dini Hari, Soetaryo, Pungky Ardani Kusuma
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 41, No 04 (2009)
Publisher : Journal of the Medical Sciences (Berkala Ilmu Kedokteran)

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Abstract

Background: Urinary tract infection (UTI) is one of most common infectious diseases in patients wuth leukemia. Some researchers showed that the prevalence of UTI was the third highest after pneumonia and gastrointestinal tract infection among children with leukemia. UTI may be affected by many factors, i.e. host, microorganism, and environment. E. coli, Klebsiella, dan Proteus are the most common bacterial etiology of UTI in leukemia. Objective: The aim of this research was to know the risk 'factor of UTI in children with leukemia. Method: This research used case-control design. Subjects of this study were children (0-15 years old) with leukemia who came to Department of Pediatrics, Dr. Sardjito Hospital since January st, 2000 until October 3", 2008. There were 38 patients in case group and 109 patients in the control group. Data collected from medical records were age, gender, nutritional status, type of leukemia, treatment phase of leukemia, and absolute neutrophil count. Risk factors analyzed were age, gender, nutritional status, and neutropenia. UTI was diagnosed by bacterial culture and bacterial count. Result: Univariate analysis showed that female gender was the risk factor of UTI (OR 2.35; CI 1.10- 5.00), meanwhile age less than 5 years old (OR 0.48; CI 0.22-1.06L poor-fair nutritional status (OR 1.20; CI 0.52-2.78), and neutropenia (OR 0.73; CI 0.35-1.55) were not risk factors of UTI. Multivariate analysis showed that female gender was the risk factor of UTI (OR 2.36; CI 1.08-5.14). Conclusion: Female gender was a risk factor of UTI in children with leukemia Keywords: leukemia - children - gender - urinary tract infection - risk factors
Sidik jari penduduk Patakbanteng, Dieng, Wonosobo Adi Soekarto Adi Soekarto
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 5, No 01 (1973)
Publisher : Journal of the Medical Sciences (Berkala Ilmu Kedokteran)

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Abstract

keywords: antropologi, sidik jari, cristae cutaneae
Breast milk, weight loss and hyperbilirubinemia in fitllterm newborn infants in the first week of life Achmad Surjono Achmad Surjono
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 25, No 01 (1993)
Publisher : Journal of the Medical Sciences (Berkala Ilmu Kedokteran)

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Abstract

The objectives were to find out the proportion of hiperhilinthinemia in term of breast-fed newborn infants, the figure of their weight loss and any significant difference in weight loss between hyperbilirubinemic group as compared with control.The subjects consist of a total of 210 singleton full-term newborn babies delivered in Dr. Sardjito Hospital from January 1 to June 30, 1992, with 5 minute Apgar score more than six and on permission of the mothers.The serum total bilirubin (TB) and unbound bilirubin (UB) were measured on day 3 and 5. TB concentration was measured spectrophotometrically and UB level was determined by peroxidase oxidation method using UB-analyzer, an automated micromethod. Body weight and first week conditions of the infants were recorded daily. Mean (± SD) TB and UB values in the third day were 10.30 ± 3.42 mg% and 0.24 ± 0.16 p.g%, respectively. The proportion of hyperbilirubinemia was 11.9%, in whom 44% received phototherapy (UB level 0.5 pg%). The mean weight loss (%) was 3.95 ± 1.84: No statistically significant difference on weight loss was found between hyperbilinthinemic and control group (p > 0.05).Hyperbilirubinemia in breast-fed term newborn infants can be considered a minor problem. Considering the benefit of mother milk, in particular for exclusive breast feeding, temporary cessation of breast feeding is not needed. On the contrary, more frequent suckling is advised with a close observation of UB levels.Key Words : breast feeding fulltenn infants hyperbilirubinemia unbound bilirubin weight loss
Accuracy of standard test of renal function status IKA-1984 Lydia Kosnadi Lydia Kosnadi
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 29, No 01 (1997)
Publisher : Journal of the Medical Sciences (Berkala Ilmu Kedokteran)

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Abstract

Measurements of standard inulin clearance and endogeous creatinine clearances were performed simultaneously in 112 children aged 2-14 years suffering from renal diseases. To diagnose the status of these renal functions, normal or decreased, a standard renal function test, namely IKA-1984, was used. The aim of this study was to investigate the accuracy of IKA-1984 compared with the other four standard renal function tests (i.e. Schwartz-1976, Feld-1990, Barratt-1975 and Chantler-1976). The data analysis used was clinical agreement in the interpretation of diagnostic tests. The results revealed very high kappa indexes (>0,80), providing IKA-1984 was accurate.Key words : inulin and creatinine clearances - renal function tests - accuracy - clinical disagreement - kappa index
The influence of stigma and depression on quality of life of leprosy patients Jenny MC Siagian, Carla R Marchira Agnes S. Siswati
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 41, No 01 (2009)
Publisher : Journal of the Medical Sciences (Berkala Ilmu Kedokteran)

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Abstract

Background: Stigma attached to leprosy-affected individuals is one of the strongest stigma of diseases. Depression is often occurred to many lepers. Stigma and depression are two factors which affect the quality of life of the lepers. Objective: To determine whether stigma and depression affect the quality of life of leprosy patients in Dermatovenereology outpatient clinic at RSUP Dr Sardjito Hospital. Methods: It was a quantitative and cross-sectional research. The quantitative analysis was conducted with chi-square and multiple regression methods. Result: There was no significant correlation between stigma and quality of life of leprosy patients. The factors which significantly correlated with quality of life were gender, income, and depression score (p < 0.051. Depression score significantly affected the quality of life (B 1.876; P < 0.05; CI 1.166-36.5661. Conclusion: Depression affected the quality of life more than deformity and demographic factors among leprosy patients in Dermatovenereology outpatient clinic at RSUP Dr Sardjito Yogyakarta. Key words: stigma - depression - lepro
Identitication offastigioblabar pathways by horseradish peroxidase method Abdulcholiq Chuseri Abdulcholiq Chuseri
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 20, No 01 (1988)
Publisher : Journal of the Medical Sciences (Berkala Ilmu Kedokteran)

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Abstract

In this experiment the fastigial projection to the paramedian reticular nucleus was investigated by means of retrograd axonal transport of horseradish peroxidase (HRP) in the rabbit cerebellum. Following HRP injection in various regions of the paramedian reticular nucleus of the medulla oblongata, labelled cells were found in the fastigial nucleus on both sides with a greater preponderance on the contralaterai side. Most of the labelled cells were distributed in the rostra] and medial regions of the fastigial nucleus, after HRP injection in the area of the paramedian reticular nucleus, proved that the fastigial neurons project their axons to the paramedian reticular nucleus.Key Words: fastigiobulbar pathways - horseradish peroxidase - fastigial nucleus - paramedian reticular nucleus - medulla oblongata
Phimosis post-circumcisi: Laporan Kasus Armies Armies
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 9, No 03 (1977)
Publisher : Journal of the Medical Sciences (Berkala Ilmu Kedokteran)

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Abstract

keywords: preputium, kuman anerob, vibrio, spirochetes
Melanogenesis in freckles patients analysis in facultative color of Melayu ethnic with skin phototype IV & V Catharina Sagita Catharina Sagita
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 36, No 3 (2004)
Publisher : Journal of the Medical Sciences (Berkala Ilmu Kedokteran)

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Abstract

Background: Patients with lack of DNA repair capacity syndrome prone to have skin cancers and usually have freckles on their skin. Freckles is considered as a risk factor for skin cancer. Repair of sun induced DNA damage was proved to stimulate melanogenesis. The difference of melanogenesis capacity between freckles and non freckles peoples has never been studied.Objective: To determine the difference of melanogenesis capacity between freckles and non freckles patients by measuring the difference of facultative-constitutive skin color in Melayu peoples with skin ptohotype IV-V.Method: A case control study was performed to determine the difference of melanogenesis capacity between 31 freckles subjects and 32 non freckles subjects.Result: There was no significant difference (p> 0.05) in melanogenesis capacity between freckles and non freckles subjects.Conclusion: There is no difference of melanogenesis respon between freckles and non freckles patient.Key words: freckles, melanogenesis, skin color, IV-V phototype skin
The correlation between the absolute eosinophil count and the degree of asthma attack in children Sumadiono Sumadiono
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 33, No 03 (2001)
Publisher : Journal of the Medical Sciences (Berkala Ilmu Kedokteran)

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Abstract

Background: The presence of eosinophil in the blood count during an asthmatic attack has been the focus of study. More airway collapse occured in the eosinophil-positive patients, even the eosinophil-positive patients had a much higher incidence of respiratory failure and mechanical ventilation use than the eosinophil-negative group.Objectives: The purpose of this study was to know the correlation between the eosinophil count and the degree of the asthma attack in children.Methods: The subjects of the study were medical records of the asthmatic children who were hospitalized in Sardjito Hospital from 1995 to 2000. The asthma criteria was according to the international consensus. The asthma attack degree evaluation was according to GINA classification. Exclusion criterias: the patients with parasitic infection and no asthmatic respiratory disturbances patients.Results: There were 169 asthmatic patients hospitalized in Sardjito Hospital from 1995 to 2000. The incidence of the hospitalized asthmatic patients was tend to increase from year to year. The percentage of the asthmatic patients with mild and severe degree attack tend to increase. The mean of the absolute eosinophil count in some degree attack group were 143.4 in mild 221.9 and in severe degree attack group were 350.7.Conclusion: There was no significant difference of the absolute eosinophil count between some, mild and severe degree attack of the asthma patients.Keywords: asthma - children - eosinophil - degree of attack

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