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Journal of the Medical Sciences (Berkala Ilmu Kedokteran)
Published by Universitas Gadjah Mada
ISSN : 01261312     EISSN : 23563931     DOI : http://dx.doi.org/10.19106/JMedSci005303202101
Core Subject : Science,
Immunology & microbiology Neuroscience
Journal of the Medical Sciences (JMedSci) or Berkala Ilmu Kedokteran (BIK) is an international, open-access, and double-blind peer-reviewed journal, published by Faculty of Medicine, Public Health and Nursing, Universitas Gadjah Mada Yogyakarta Indonesia. JMedSci aiming to communicate high-quality articles in the areas of biomedical science from basic to clinical sciences.The journal welcomes papers from original articles, case reports, reviews, and book reviews. All papers published in JMedSci are freely available as downloadable pdf files. The journal began its publication on March 1973 and published quarterly (January, April, July, and October). JMedSci is abstracted and indexed in DOAJ, Crossref, Google Scholar, Sinta, Indonesia One Search. JMedSci is accredited by Directorate of General Higher Education, the Ministry of Research, Technology, and Higher Education, Indonesia
Arjuna Subject : Kedokteran - Kedokteran (Lain-Lain)
Articles 2,170 Documents
 124   125   126   127   128 
Kedokteran Sebagai Ilmu Pandangan Kedokteran Sekarang Teerhadap dirinya T. Jacob T. Jacob
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 13, No 01 (1981)
Publisher : Journal of the Medical Sciences (Berkala Ilmu Kedokteran)

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Abstract

The author defines medicine as efforts to understand, maintain and manage health condition of human beings, as individuals as well as members of a society, in a biosocial matrix. Thus, three sets of disciplines are involved, i. e. the basic medical sciences, the clinical medical sciences and the social medical sciences.Besides, four aspects of medicine should be taken into consideration, namely medicine as science, technology, art and craft. Also, attention should be paid to the fact that diseases and medical interventions could occur at any level of the I :ing system, each having its own charac• teristics, and with emergents appearing in cross:level surveys.The unavoidable subspecialization in modern medicine should be balanced by transdisciplinary communication and interdisciplinary efforts, and by holistic approach to health problems utilizing the biosociomedical concept of health. Four tracts of study are suggested in medical education, i. e. population medicine, surgical sciences, medical sciences, and basic medical sciences.In conjunction with these steps early compartmentalization in the senior high school curriculum should be avoided.Key Word:: medical education - scientific medicine - living systems - concepts of disease - medical specialization
Survai Aedes Aegypti L. (Diptera: Culicidae) Di Yogyakarta. Tempat Perkembangbiakan Sugeng Juwono Sugeng Juwono
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 6, No 03 (1974)
Publisher : Journal of the Medical Sciences (Berkala Ilmu Kedokteran)

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Abstract

Keyword :Aedes Aegypti L, Tempat Perkembangbiakan
α-Lipoic acid inhibit the decrease of collagen deposition in ultravioled B-irradiated cultured normal human skin fibroblasts cell culture Arum Krismi Satiti Retno Pudjiati Yohanes Widodo Wirohadidjojo
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 43, No 02 (2011)
Publisher : Journal of the Medical Sciences (Berkala Ilmu Kedokteran)

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Abstract

Repeated ultraviolet B (UVB) irradiation on human skin has been considered to be responsible in premature agingprocess because UVB has been proved to inhibit collagen deposition and accelerates collagen degradation. Clinicalstudies showed that topical usage of 5% α-lipoic acid (ALA) improved the clinical appearance of photoaged skin.However, the effect of ALA on collagen deposition and degradation in UVB-irradiated normal human skin fibroblastsculture has not been reported. The aim of the study was to investigate the effect of ALA on collagen deposition anddegradation in UVB-irradiated cultured normal human skin fibroblasts. Culture of normal human skin fibroblasts weretreated with 0, 125, 250, 500 μM ALA diluted in complete Dulbecco’s Modified Eagle’s Medium (DMEM) andirradiated with 300 mJ/cm2 UVB. The mean collagen deposition and degradation’s level were measured by Siriusred assay and read with spectrophotometer at λ 550 nm. Mean difference of collagen deposition as expressed byoptical density (OD) between normal human skin fibroblasts cell after UVB irradiation and without UVB irradiationwas analyzed by Wilcoxon signed-ranks test and Friedman test, while mean difference collagen degradation wasanalyzed by one way analysis of variance (ANOVA) and paired t test with 95% confidence level (p<0.05). Theresults showed that ALA 125 μM inhibited the decrease of collagen deposition significantly (p<0.05), though higherconcentrations did not. However, ALA did not inhibit collagen degradation increment (p>0.05). In conclusion, ALAinhibited the decrease of collagen deposition, but did not inhibit collagen degradation in UVB-irradiated normalhuman skin fibroblasts culture.Key words: α-lipoic acid - collagen - human skin - fibroblasts – UVB - irradiation
FlOariasis caused by nonpedodic form of Brugia malayi among Bugis and Banjar settlers in East Kalimantan FA Sudjadi FA Sudjadi
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 30, No 01 (1998)
Publisher : Journal of the Medical Sciences (Berkala Ilmu Kedokteran)

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Abstract

Nonperiodic form of B. malayi was recently discovered as a new infraspecific variant (new subspecies) of filarial parasite found among Dayak Indigenous people living scattered in deep forest of East Kalimantan. In this research, clinical or blood (including membrane filter concentration method) examinations were carried out on Bugis or Banjar tribais in kampongs or more open areas in East Kalimantan. The malayan filariasis infections were detected among them, but not in high prevalence nor microfilarial density, such as found in two villages in Mahakam delta or another one In Bontang area, Kutai regency. The clinical manifestations, however, were not severe nor specific.Key words: Brugia malayi - nonperiodic form - Bugis and Banjar settler - natural selection pressure - parasite dispersal.
Eyelid reconstruction after extirpation of lid tumor Mu&#039;tasimbillah Ghozi Mu&#039;tasimbillah Ghozi
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 18, No 02 (1986)
Publisher : Journal of the Medical Sciences (Berkala Ilmu Kedokteran)

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Abstract

Extirpation of eyelid benign tumor, while the vision is still good, must be followed by lid reconstruction to protect the eyeball. The means of such reconstruction to make the lid function are optimal. A case of lid reconstruction after lid benign tumor extirpation with the remain of skin and the orbicular oculi muscle has been reported. The reconstruction was carried out by replacing the lost tarsoconjunctival tissue with the opposite tarsoconjuncdval tissue. The blepharoraphy was maintained until the cicatrical tissue formation was completed. Key Words: lid tumor extirpation - reconstruction of superior levator palpebral muscle - replacement of tarsoconjunctival tissue - blepharoraphy - ophthalmic surgery
Perubahan-Perubahan Segmental pada Pertumbuhan Anak Perempuan Umur 7-10 Tahun di Yogyakarta Adi Soekarto Adi Soekarto
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 12, No 01 (1980)
Publisher : Journal of the Medical Sciences (Berkala Ilmu Kedokteran)

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Abstract

The growth in stature actually consists of segmental growth, because it could be divided into various segments, i. e.: head and neck, trunk, and upper and lower leg. All segments grow independently under their own velocity; the stature is the same as the sum of the length of all segments. The body width also grows at about equal'speed as the trunk.Four samples of girls, between seven to ten years of age, are taken from the collected data in the Department of Physical Anthropology, Gadjah Mada University Faculty of Medicine. The increment of body length is mainly caused by leg length between seven to eight and nine co ten years of age, and by the trunk length between eight to nine years of age.Key Words: segmental growth - stature - Indonesian children - trunk length - leg length
Potential risk of adverse event in patients undergo elective urologic surgery Ratih Wulansari Ratih Wulansari
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 37, No 03 (2005)
Publisher : Journal of the Medical Sciences (Berkala Ilmu Kedokteran)

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Abstract

Background: Almost all medical treatment may pose risk. The risk of adverse event in patients undergoing surgery is higher than those who undergo non surgical intervention. The incidence of adverse event varies from 3.7% in the US to 16.7% in Australia. Basically, most of the adverse events are preventable. It is therefore recommended to implement clinical risk management in health care services. Objective: To identify risk of adverse event among patients undergo elective urologic surgeryMethod: A cross sectional study was carried out to collect prospective data on patients underwent elective urologic surgery at Tabanan General Hospital between August-September 2005. Data on the risk of adverse event were identified since patients were admitted to Hospital, underwent pre-op preparation and surgical procedure. Follow up was carried out until 30 days after surgical procedureResult: Seven major potential risks were identified, i.e.(1) pre-operative stay> 3 days (28.85%);(2) patients' risks for surgery (44.23%); (3) prophylactic antibiotic were given > 2 hours before surgery (88.46%); (4) ASA > (82.69%); (5) preoperative hair removal > 2 hours before surgery (86.53%); (6) use of intravenous line more than 24 hours (26.92%); and (7) use of urine cathether > 6 days (25%). It is found that pre-operative stay > 3 days was significantly related to the occurrence of adverse event.Conclusion: Pre-operative stay > 3 days contributed significantly in the occurrence of adverse event among patients underwent elective urologic surgery. However, other risk factors were not significantly related to adverse event due to small sample size.Key words: elective urologic surgery - risk - clinical risk management - clinical governance 
Cytotoxic selectivity of MJC0.3 and MJC0.5, acidic ribosome-inactivating proteins isolated from Mirabilis jalapa L. leaves against various cancer cell-lines Sismindari Mae Sri Hartati, Adhyatmika Retno S. Sudibyo
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 42, No 01 (2010)
Publisher : Journal of the Medical Sciences (Berkala Ilmu Kedokteran)

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Abstract

Mirabilis jalapa L. contains basic (MJ30) and acidic (MJC) Ribosome-inactivating proteins (RIPs). Further purificationof MJC has been found two RIPs, MJC0.3 and MJC0.5. This study is aimed to prove the cytotoxic selectivity ofMJC0.3and MJC0.5against many cancer cell-lines and normal cell line. The two RIPs, MJC0.3and MJC0.5were testedtheir cytotoxic effect on 8 human cancer cell lines and normal cell using MTT assay compared with MJC protein.The highest cytotoxic activities of MJC0.3and MJC0.5were against EVSA-T followed by T47D, HeLa,WiDR, SiHa,Raji, NS1, andMCF7, with the IC50 of 59.3, 102.4, 162.9, 190.5, 249.5, and 304.5 μg/mL, respectively for MJC0.3and 32.8, 75.5, 86.0, 108.3, 346.7, and 220.06 μg/mL, respectively for MJC0.5. Based on these IC50 values,MJC0.3 and MJC0.5 were specific to EVSA-T and T47D, whereas they were not selective against Raji and SiHa(SI<10.0). It can be concluded that he acidic RIPs isolated from M. jalapa L. leaves was potential to be developedas anticancer agents for breast cancer.Key words: acidic RIPs – M. jalapa L.- cytotoxic selectivity - cancer cell lines.
Relation between participating in playgroup with child development Elsa Maimon Djauhar Ismail Mei Neni Sitaresmi
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 44, No 02 (2012)
Publisher : Journal of the Medical Sciences (Berkala Ilmu Kedokteran)

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Abstract

Playgroup is one of early education programs to promote child development. A cohort study found that early education program resulted in better social performance. However this study did not evaluate the influence of this program on child development. The aim of this study was to evaluate whether participating in playgroup relates to child development achievement. This was a cross sectional study conducted on children in Yogyakarta Special Region. The subjects were children in the first month of kindergarten. The child development was tested using Denver II. Other data were collected by questioners and filled by their parents. Chi-square test was used to analyze the factorsthat influenced the child development. One hundred and seventy two children participated in the study. It was found that the development achievement of children participating in playgroup were 3.2 times better than those not participating in playgroup (p=0.002; OR: 3.248; 95% CI: 1.558-6.774), whereas gender, education of parents, number of slibings, and birth weight were not associated with the child development achievement. In conclusion, joining the playgroup relates to the child achievement development.Keywords: playgroup - child development - Denver II test - kindergarten - education
Hoffa fractures (corona/ fractures) of the femoral condyle. A case report Armis Armis
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 29, No 02 (1997)
Publisher : Journal of the Medical Sciences (Berkala Ilmu Kedokteran)

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Abstract

Hoffa Fracture is a fracture at femoral condyle caused by direct injury of the knee at flexion position; there fore the articular surface is broken. Distal fragment of fracture can be displaced or undisplaced. The Hoffa fracture is divided into three types according to prognostic implication. Type I, the intra articular fracture line reaches the supracondyle of the femur and some of the soft tissues still attached to the distal fragment. Type II, intra articular fracture without any attachment of the soft tissue to the distal fragment. and type III where the fracture line slight anteriorly and proximally to the condyle of the femur with some attachment of the soft tissues and ligaments to the distal fragment. A case of young motor cyclist who involved in collision against a bridge is reviewed. He has type I Hoffa fracture Which is equal to grade III B Gustilo classification system. The conservative procedure of open wound management and skeletal traction was adequate. The problem was that, the radiographic interpretation was difficult if the anterior part of the femoral condyle was intact, undisplaced or slightly displaced. Therefore CT-Scan and tomography were indicated. In type I and type III Hoffa fracture, some soft tissue structures remain attached to the distal condyle fragment and that there will be some blood supply to this fragment. However, in type II fracture the soft tissue may completely be unattached especially type II C and it could predispose to avascular necrosis or nonunion.Key Words : Fracture - intraarticular - femoral condyle - avascular necrosis - non-union

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