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Journal of the Medical Sciences (Berkala Ilmu Kedokteran)
Published by Universitas Gadjah Mada
ISSN : 01261312     EISSN : 23563931     DOI : http://dx.doi.org/10.19106/JMedSci005303202101
Core Subject : Science,
Immunology & microbiology Neuroscience
Journal of the Medical Sciences (JMedSci) or Berkala Ilmu Kedokteran (BIK) is an international, open-access, and double-blind peer-reviewed journal, published by Faculty of Medicine, Public Health and Nursing, Universitas Gadjah Mada Yogyakarta Indonesia. JMedSci aiming to communicate high-quality articles in the areas of biomedical science from basic to clinical sciences.The journal welcomes papers from original articles, case reports, reviews, and book reviews. All papers published in JMedSci are freely available as downloadable pdf files. The journal began its publication on March 1973 and published quarterly (January, April, July, and October). JMedSci is abstracted and indexed in DOAJ, Crossref, Google Scholar, Sinta, Indonesia One Search. JMedSci is accredited by Directorate of General Higher Education, the Ministry of Research, Technology, and Higher Education, Indonesia
Arjuna Subject : Kedokteran - Kedokteran (Lain-Lain)
Articles 2,170 Documents
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Disseminated intravascular coagulation Suhardi DA Suhardi DA
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 23, No 04 (1991)
Publisher : Journal of the Medical Sciences (Berkala Ilmu Kedokteran)

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Abstract

Bleeding may result from abnormalities' of platelet, blood vessel walls, or coagulation. Acquired deficiency of coagulation factors is usually the result of impaired production or increased extravascular loss. Inappropriate intravascular utilization of coagulation factors, which is usually prevented by continuous rapid blood flow, circulating inhibitors of procoagulants, and removal of activated clotting factors, may result as defibrinogenation syndrome, disseminated intravascular coagulation, or consumption coag-ulopathy. Factors responsible for the diseminared intravascular coagulation include release of thromboplastic material into the circulation, endothelial damage, endotoxemia, antigen-antibody reactions, hypertension, hypoxia, acidosis, and re uculoendothelial blockage.This paper describes the clinical manifestations, pathogenesis and management of the disseminated intravascular coagulation which might be not so rare in the clinics.Key Words: disseminated in travascularcoagulation -hemon-hage.-defibrinogenation syndrome - coagulopathy -procoagulant inhibitor
Pengujian kadar iodium total dalam urin dengan metode destruksi basah dan destruksi kering Iswani S Iswani S
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 28, No 01 (1996)
Publisher : Journal of the Medical Sciences (Berkala Ilmu Kedokteran)

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Abstract

Total iodine contents in the urine samples were directly tested with and without destruction using Ion Selective Electrode (ISE) method. The dry destruction was carried out with volume variation of 0.5 M NaOH solution and wet destruction was done with 4 ml of concentrated H2504 and 1 ml of concentrated HNO3 mixture, followed by volume variation of 1% p-aminophenol solution and temperature to reduce 103- form to form. The Chloride ion contents were also determined using technique. It was found that the optimum of NaOH amount, the optimum of 1% p-aminophenol and temperature (wet digestion) was 2 ml, 12 ml, and 60°C respectively. The chloride ion contents in 6 urine samples were in the range of 2373-4495 ppm and didn't interfere on r determination. The total r contents in the six samples without destruction,using wet and dry destructions were in the range of 280-392 ppb, 291-505 ppb and 306-516 ppb respectively. The t-test showed that the total Iodine content in urine samples with and without destructions was significantly different.Key words: Iodine - urine - ISE method - wet and dry destruction - chloride
Effect of vitamin C and vitamin E supplementation on lipid peroxide of lactating woman Prasetyastuti Endang Sri Sunarsih
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 40, No 01 (2008)
Publisher : Journal of the Medical Sciences (Berkala Ilmu Kedokteran)

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Abstract

Background: Vitamin C and vitamin E are antioxidants that trapp free radical that is continuously formed in aerobic organism as an effect of aerobic respiration in mitochondria and substrate oxidation. The quantity and quality of breast feeding (ASH are influenced by nutritional status and health of the mother. The ASI vitamin C level is very much related to everyday intake and plasma vitamin C of the mother.Objective: To know the effect of vitamin C and vitamin E supplementation on peroxide lipid (MDA) of lactating women.Methods: This was pretest and post test experimental design. The subjects were twenty three lactating women who live in Pakem District, Sleman 19-38 year olds they received 75 mg vitamin C and 2 mg vitamin E every two days for a period of one month. Blood sample was taken from cubit vein before and after supplementation. Determination of vitamin E level used spectrofluorometer, whereas vitamin C and MDA level were determined by spectrophotometer. The data was analyzed with Pearson correlation test Results: the correlation of vitamin C vs MDA; vitamin E vs MDA and vitamin C together with vitamin E vs MDA were r - 0.528; r square 0.276 and p = 0.05; r -0.671, r square 0.451, p = 0.009 and r 0.690; r square 0.476 and p= 0.028, respectivelyConclusion: the effect of vitamin E to MDA was stronger than vitamin CKeyword.: vitamin C - vitamin E - peroxide lipid - free radical - lactating mother
Hysterosalpingography in infertility Bagaswoto Poedjomartono Bagaswoto Poedjomartono
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 16, No 01 (1984)
Publisher : Journal of the Medical Sciences (Berkala Ilmu Kedokteran)

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Abstract

Hysterosalpingography is performed by injecting contrast media into the uterus to visualize the uterine cavity and Fallopian tubes. Water-soluble contrast media are used in these examinations. Hysterosalpingographic examination is very important for the diagnosis of infertility and some gynecologic abnormalities.Between January-December 1981 hysterosalpingography had been performed in 79 cases of primary infertility, 28 cases of secondary infertility and 3 cases with abortion history. The hysterosalpingogram demonstrated that 23.64% of all cases were bilateral non-patent and 21.8% unilateral non-patent. Hydrosalpinx was found in 22 cases, 17 cases with bilateral or unilateral non-patent tubes and 5 cases with patent ones. Ten cases showed paratubal filling assosiated with patent and non-patent tubes.Key Words: hysterosalpingography - hydrosalpinx - infertility - contrast media - Fallopian
Prevalensi Penyakit Penyebab Kebutaan di Bagian Mata Rumah Sakit Universitas Gadjah Mada 1975 Gunawan Gunawan
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 8, No 01 (1976)
Publisher : Journal of the Medical Sciences (Berkala Ilmu Kedokteran)

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Abstract

Kebutaan di Bagian Penyakit Mata Rumah Sakit Universitas Gadjah Mada tahun 1975 ditemukan sebanyak 1476 orang, merupakan 12.39% dari seluruh pcnderita haru. Visus 3/60 atau kurang dipergunakan sebagai standar buta. Kebutaan pada laki-laki lebih banyak daripada wanita, baik itu kebutaan pada satu mata maupun kebutaan pada kedua mata. Kebutaan pada golongan umur 41-50 tahun ditemukan paling banyak, kemudian golongan umur 51-60 dan 11-20 tahun. Kebutaan terbanyak memiliki visus 1/60 (23.44%).Adapun kebutaan terbanyak di Bagian Penyakit Mata disebabkan oleh cataracta, keratitis, myopia dan glaucoma (di Inggris: cataracta, glaucoma, myopia clan kelainan kongenital).
Absolute and relative lymphocyte counts in dengue infection Bambang Ardianto Bambang Ardianto
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 34, No 04 (2002)
Publisher : Journal of the Medical Sciences (Berkala Ilmu Kedokteran)

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Abstract

Background: Dengue infection is one of Indonesia's health problems. Lymphocytes are thought to be involved in dengue pathogenesis.Objectives: To determine whether there were any differences on absolute and relative lymphocyte counts between dengue and non-dengue febrile patients and among dengue fever (DF), dengue hemorrhagic fever without shock (DHF, dengue shock syndrome (DSS), and non-dengue (ND) patients.Methods: A cross-sectional study was conducted on dengue and non-dengue patients hospitalized at "Empat Lima" Hospital, Yogyakarta, during the period of November 23, 2001-January 22, 2002. The diagnosis of dengue infection was confirmed by HI test. Absolute and relative lymphocyte counts were obtained from serial peripheral blood films stained with Giemsa's staining.Results: Thirty-eight DF, 10 DHF, 16 DSS, and 86 ND patients were involved in this study. Absolute and relative counts of each degree were compared each other from the third day until the eighth day after the onset of fever. Absolute lymphocyte counts of dengue patients were higher than those of non-dengue patients on day 5 (p=0.047) and 6 (p =0.022). Absolute lymphocyte counts of DHF patients were higher than those of DF, DSS, and ND patients on day 5 (DF vs. DHF, p =0.003; DHF vs. DSS, p=0.001; ND vs. DHF, p(0.001).Absolute lymphocyte counts of DHF patiens were higher than those of ND patiens on day 6(p=0.018).Relative lymphocyte counts of Df patiens were higher than those of DSSpatiens on day 6(p=0.023), while relative lymphocyte counts of ND patiens were higher than those of DSS patiens on day 7 (p=0.026).Conclution:there were significant differences in absolute lymphocyte counts between dengue and nondengue patiens, DF and DSS patiens, and ND and DSS patiens.Key words:lymphocyte count, dengue infection, dengue shock syndrome, non-dengue infection
Calcitriol infra venous therapy in routinely hemodialyzed patients with secondary hyperparatyroidism Mochammad Sja'bani Mochammad Sja'bani
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 31, No 02 (1999)
Publisher : Journal of the Medical Sciences (Berkala Ilmu Kedokteran)

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Abstract

Background: Secondary hyperparathyroidism is common in patients with chronic renal failure. Secondary hyperparathyroidism with vitamin D deficiency may increase renal osteodystrophy.Objective: To determine the blood intact parathormone (iPTH) level in routinely hemodialyzed patients with secondary hyperparathyroidism undertaking calcitriol intravenous therapy once in two weeks. Methods: a double blind randomized clinical trial had been done in 32 chronic renal failure patients from 41 secondary hyperparathyroidism who underwent regular hemodialysis in Dr. Sardjito Hospital Yogyakarta. All patients received intravenous calcitriol 11.1.g or placebo twice a week after dialysis for 2 weeks. The proportion of the decrease of iPTH level at least 30%; calcium, and phosphate levels in calcitriol (16 patients) and in placebo (16 patients) group were measured.Results: The decrease of iPTH at least 30% in calcitriol group were 12 patients (75%) and in placebo group 6 patients (37.5%) (p> 0.05). In calcitriol group there were 4 patients (25%) with hypercalcemia and 6 patients (37.5%) with hyperphosphatemia, whereas in placebo group 5 patients (31.3%) with hypercalcemia and 5 patients (31.3%) with hyperphosphatemia (p>0.05).Conclusion: Calcitriol intravenous therapy for 2 weeks might decrease iPTH at least 30%.Key words: secondary hyperparathyroidism - chronic renal failure - osteodystrophy - intact parathormone -calcitriol
Obat pilihan: ada, mujarrab dan murah Anonim Anonim
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 22, No 01 (1990)
Publisher : Journal of the Medical Sciences (Berkala Ilmu Kedokteran)

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Abstract

Kata Kunci: Obat murah
The Effect of budesonide on lymphoid and non-lymphoid cell profiles, and la-antigen expression in rats with experimental colitis Marsetyawan HNE Soesatyo Marsetyawan HNE Soesatyo
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 27, No 01 (1995)
Publisher : Journal of the Medical Sciences (Berkala Ilmu Kedokteran)

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Abstract

Kortikosteroid merupakan obat yang efektif terhadap peradangan, seperti penyakit peradangan usus kronis. Penelitian ini bertujuan untuk mengetahui pengaruh pamberian kortikosteroid lokal, yakni budesonide colitis experimental pada tikus, khususnya pengaruhnya terhadap populasi sel limfoid dan nonlimfoid, serta ekspresi antigen-la (molekul major histocompatibility complex (MHC) kias II). Di camping itu diteliti pula peran molekul-molekul adhesi, seperti intercellular adhesion molecules (iCAM-1) dan lymphocytes function associated antigen (LFA-1) setelah pemberian obat tersebut.Model colitis dibuat dengan pemberian secara intracolon zat hapten: 2,4,6-trinitrobenzene sulphonlc acid (TNBS) dalam etanol, berdasarkan metode standar. Obat budesonide diberikan deism deals tunggal dan ganda sebanyak 0,25 ml larutan 104 M secara lokal ke dalam colon dengan menggunakan kateter. Populasi sal limfoid dan nonlimfoid di sepanjang mukosa dan submukosa, termasuk plak Payer (PP) dan jaringan limfoid di daerah proksimal colon diperiksa dengan teknik imunositokimiawi. Ekspresi MHC Ida* ii dan molekul adhesi diteliti menggunakan panel antibodi monoklonal (AbMo).Dosis ganda budesonide (3x) *angst efektif untuk mengobati colitis akut; ini dapat diamati dad gejala-gejala klinis yang menghilang. Pemeriksaan histologik menunjukkan penurunan nyata jumlah subpopulasi makrofag, seperti sel EDI% ED2* dan ED3+. Intensitas ekspresi la dan ekspresi ICAM-1, LFA-1 mengurang, sdang lainnyaedangkan migrasi sal neutrofil dan sel radang lainnya menghilang.Key words : inflammatory bowel disease -- TNBS colitis -- budesonide-lymphoid and non-lymphoid cell populations -- MHC class II expression -- adhesion molecules.
Candida albicans biofilm: formation and antifungal agents resistance Tri Wibawa
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 44, No 02 (2012)
Publisher : Journal of the Medical Sciences (Berkala Ilmu Kedokteran)

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Abstract

Candida sp are the most common fungal pathogens causing fatal health care associated infections.Among the genus of Candida, Candida albicans is the most frequent species isolated frompatients. The notorious C. albicans infection is the ability of this dimorphic fungus to formbiofilm. Biofilm has been pointed as a dynamic phenotypic switching in bacteria and fungi,which may result in higher morbidity and mortality in human beings. This review addresses thebasic explanation of biofilm formation which is characterized by the antifungal agents resistance.The factors that influence C. albicans biofim formation and antifungal agents resistance arediscussed.Key words: Candida sp – antifungal – resistance – biofilm - pathogenecity

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