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Journal of the Medical Sciences (Berkala Ilmu Kedokteran)
Core Subject : Science,
Journal of the Medical Sciences (JMedSci) or Berkala Ilmu Kedokteran (BIK) is an international, open-access, and double-blind peer-reviewed journal, published by Faculty of Medicine, Public Health and Nursing, Universitas Gadjah Mada Yogyakarta Indonesia. JMedSci aiming to communicate high-quality articles in the areas of biomedical science from basic to clinical sciences.The journal welcomes papers from original articles, case reports, reviews, and book reviews. All papers published in JMedSci are freely available as downloadable pdf files. The journal began its publication on March 1973 and published quarterly (January, April, July, and October). JMedSci is abstracted and indexed in DOAJ, Crossref, Google Scholar, Sinta, Indonesia One Search. JMedSci is accredited by Directorate of General Higher Education, the Ministry of Research, Technology, and Higher Education, Indonesia
Articles 2,170 Documents
Prophylactic uterotonic agent to avoid postpartum bleeding on normal vaginal delivery Ibnu Pranoto Ibnu Pranoto
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 33, No 04 (2001)
Publisher : Journal of the Medical Sciences (Berkala Ilmu Kedokteran)

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Abstract

Objective: To compare the volume of blood loss after normal vaginal delivery that have been given prophylactic uterotonic agents, 2.5 IU oxytocin, 5 IU oxytocin, 2.5 IU oxytocin plus 0.2 mg ergometrin, and 5 IU oxytocin plus 0.2 mg ergometrin.Methods: A Randomized control trial study was performed, 22 normal vaginal deliveries were given 2.5 IU oxytocin. 5 IU oxytocin was for 26 normal deliveries, 2.5 IU oxytocin plus 0.2 mg ergometrin for 29 deliveries and 5 lU oxytocin plus 0.2 mg ergometrin for 27 deliveries. The agents were administered intramuscularly or intravenously at a time of crowning. One way-anova test was used in this study. Intrapartum mothers with the normal vaginal delivery in Obstetrics and Gyneclogy Department of Sardjito General Hospital, Yogyakarta and Soeradji General Hospital, Klaten, between April 1't and July 28th 1988. Results: There is no significant difference between the second stage blood loss in the deliveries given 2.5 IU and 5 IU oxytocin with or without ergometrin. On the other hand, administration of 2.5 IU oxytocin has been statistically significant to reduce the mean blood loss on the third stage of labor compared to the other regiments. Prophylactic 2.5 IU and 5 IU oxytocin with or without ergometrin did not show any significant difference on the fourth stage of labor. The mean of blood loss after normal vaginal delivery was statisticaly significantly reduced by giving 2.5 IU oxytocin as the prophylactic agent compared to the other treatments in this study.Conclusion: The administering of 2.5 IU oxytocin was more significant in preventing postpartum bleeding in the third stage of labor and the postpartum bleeding. Ergometrin addition to oxytocin was not proved to decrease the blood loss in any stage of labor and portpartum bleeding as well.Keywords : Prophylactic uterotonic agents - oxytocin - ergometrin - normal vaginal delivery - postpartum bleeding.
Preliminary study on congenital anomaly in DR. Sardjito General Hospital Yogyakarta M. Mansyur Romi
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 39, No 04 (2007)
Publisher : Journal of the Medical Sciences (Berkala Ilmu Kedokteran)

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Abstract

Background: Congenital anomalies and genetic diseases tend to increase and dominate hospital admittance,especially in the pediatric wards in developed countries. The spectrum of diseases in regions with lowinfant mortality rate is likely to go with such tendency It is necessary to study congenital anomalies andgenetic diseases at Dr. Sardjito General Hospital, locating in a region with much lower infant mortalityrate than that of the national average.Objective: To know the occurrence of congenital anomalies and its pattern among DR. Sardjito GeneralHospital in-patients.Method: An desricptive study was done on secondary data taken from data-base of the Hospital in 1998 –2002 period. All of admittances in that period diagnosed as primary or secondary diagnosis, with Q00 –Q99 congenital malformations, deformations, and chromosomal abnormalities according to InternationalClassisifaction of Diseases (ICD), were included. The pattern of anomaly at the Hospital was compared tothat of different population and period.Results: There were 1968 1070 males and 898 females) admittances with congenital anomalies at Dr.Sardjito General Hospital in 1998 – 2002. The proportion compared to the whole admittance was 2.06%.The most prevalent was Q35 – Q37 cleft lip and cleft palate (21.14%), followed by Q38 – Q45 othercongenital malformations of the digestive system (18.45%), Q20 – Q28 malformations of the circulatorysystem (15.65%), Q50 – Q56 malformations of genital organs (12,55%), Q00 – Q07 malformations ofthe nervous system (11.89%), Q65-Q79: malformations nd deformations of musculoskeletal system(6.40%), Q80-Q89: other congenital malformations (4.06%), Q10-Q18: malformations of eye, ear, faceand neck (3,91%), Q60-Q64: malformations of the urinary system (2.54%), Q90-Q99: Chromosomalanomalies (2,44%), and Q30-Q34: malformations of the respiratory system (0.97%).Conclusion: Congenital anomalies at Dr. Sardjito General Hospital were dominated by cleft lip and palate,and other congenital malformations of the digestive system. The pattern was similar to that of otherregions of Indonesia, and differed from Indian and European populationsKey words: congenital anomalies – genetic diseases – malformations – Dr. Sardjito General Hospital
Intracranial ependymoma and its appearance on CT Scan. Arif Faisal Arif Faisal
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 27, No 04 (1995)
Publisher : Journal of the Medical Sciences (Berkala Ilmu Kedokteran)

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Abstract

Intracranial ependymoma is an uncommon central nervous system neoplasms which happens in all age groups but has higher incidence occurring in the posterior fossa in infants and children. The location of the tumor is in the ventricle system, especially the fourth ventricle. Depending on its position to tentorium, the tumors can be divided into supratentorial and infratentorial. Hydrocephalus and calcifications usually occur in both types of tumors. Ependymomas have unspecific and varied appearance in density on computed tomography examination, but most of them are isodense. The supratentorial ependymoma tends to be hypodense, cystic-like lesion and enhanced (homogenous and nonhomogenous) after contrast, injection. The Infratentorial ependymoma are mostly hypodense and similar enhancement to supratentorial tumor. Treatments consist of surgical resection and radiotherapy, but the overall results are not very effective.Keywords : ependymoma - infratentorial tumor - supratentorial tumor - contrast enhancement
Comparasion of Sport Urine Protein Creatinine From Three Different Time Urine Samples in Children With Primary Nephrotic Jusuf Hartanto Mohammad Juffrie Pungky Ardani
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 39, No 03 (2007)
Publisher : Journal of the Medical Sciences (Berkala Ilmu Kedokteran)

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Abstract

Background: First voiding of morning urine protein/creatinine ratio on a single voided urine sample correlates well with 24 hour urine collection and can be used to detect and monitor proteinuria in children. Objective: Aim of this study was to determine whether the random urine samples can be used as reliable indicator for spot urine protein/creatinine ratio.Methods: 40 primary nephrotic syndrome children aged 1-16 years admitted to the Department of Pediatric, Dr Sardjito hospital were included in this study. Urine samples from three different times were collected: first voiding of morning urine, noon voiding and night voiding. The three samples were analyzed for protein level, creatinine level and protein/creatinine ratio of spot urine. The protein/creatinine ratio was compared and correlation was calculated according to the three different time collections.Results: There was no significant difference of noon and night protein/creatinine ratio compared with first voiding of morning urine protein creatinine ratio (p> 0.05). The correlation of protein/creatinine ratio between the three samples was significantly high (r=0.95, 0.96 and 0.98, p < 0.01).Conclusions: For quantifying proteinuria, there is convincing evidence that the random urine samples can be used to predict the level of protein excretion as measured in a 24-hour sample.Keywords: Proteinuria, protein, creatinine ratio, primary nephrotic syndrome
Current status of filariasis chemotherapy Sugeng Juwono Mardihusodo Sugeng Juwono Mardihusodo
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 15, No 03 (1983)
Publisher : Journal of the Medical Sciences (Berkala Ilmu Kedokteran)

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Abstract

Success of filariasis control still depends greatly on chemotherapy. piethylcarbamazine is so far considered as the most suitable and effective drug of filariasis in man. Its untoward reactions experienced by the treated individuals, long course of administration and incapability of removing all Wuchereria bancroftimicrofilariae in blood, however, initiate the search for more ideal antifilarials.A number of chemical compounds has been tested and shown to be active as filaricides in. experimental animals, and needs further intensive and careful clinical evaluation in man prior to its administration on a wider scale.Various methods of filaricide testing, using different filarial parasites and laboratory animals, and hindering factors arising in case of the production of a new antifflarial drug are discussed.Key Words: filariasis chemotherapy - diethylcarbamazine filaricides - filaricide testing - an tifilarial drug
Organisasi Apparat Pendidikan Di Universitas T. Jacob T. Jacob
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 7, No 04 (1975)
Publisher : Journal of the Medical Sciences (Berkala Ilmu Kedokteran)

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Abstract

key words: organisasi pendidikan di universitas
The diagnostic accuracy of clinical and blood examination for sepsis in potentially infected neonates Ari Mulyani Ari Mulyani
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 34, No 03 (2002)
Publisher : Journal of the Medical Sciences (Berkala Ilmu Kedokteran)

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Abstract

Background: Neonatal sepsis remains a diagnostic challenge due to its nonspesific symptoms. Blood culture examination which is considered to be the gold standard, sometimes it is still a problem because takes time to get the result, expensive and not every health facility is able to perform.Objective: To evaluate the diagnostic accuracy of clinical symptoms, hematologic findings and C-Reactive Protein (CRP) in neonatal sepsis.Methods: Samples were taken from potentially infected neonates admitted to the Maternal-Perinatal Unit of Dr. Sardjito Hospital, Yogyakarta, between December 1st, 2000 to March 31st, 2001 using at least one of the criteria: prematurity (15,000/pL), premature rupture of the membrane (>24 hours), thick and cloudy amniotic fluid. Clinical symptoms, total white blood cell count, total neutrophil count, platelet count, CRP, and blood culture as gold standard were examined.Results: Among 99 neonates who were enrolled in this study, the sensitivity, specificity, positive predictive value and negative predictive value of clinical symptoms were 79.3%, 75.7%, 57.5%, and 89.9%, respectively; leukopenia/leukocytosis were 27.6%, 85.7%, 44.4%, and 74.1%, neutropenia/neutrophilia were 41.4%, 71.4%, 37.5%, and 74.6%, thrombocytopenia were 79.3%, 51.8%, 40.4%, and 85.7%, positive CRP were 58.6%, 78.6%, 53.1%, and 82.1%. Parallel test (clinical manifestation, thrombocytopenia, and CRP) increasing sensitivity up to 89.7%. Specificity, positive predictive value, negative predictive value, and likelihood ratio were 44.3%, 40%, 91.2%, and 1.6, respectively. Serial test (CRP, clinical manifestation, and thrombocytopenia) increasing the spesificity up to 88.6%. Sensitivity, positive predictive value and negative predictive value were 58.6%, 68%, and 83.8%, respectively, likelihood ratio was 5,1.Conclusion: Clinical sepsis, thrombocytopenia and CRP were sufficiently accurate as diagnostic test for sepsis in potentially infected neonate. Using parallel test increased the sensitivity, where negative finding reveals no sepsis. Serial test increased specificity. There was high probability of having sepsis, if the result was positive.Key words : Neonatal sepsis - clinical symptoms - hematologic findings - C-reactive protein
Full term premature rupture of the membrane (PROM): Active management (AM) vs conservative management (CM) Sulchan Sofoewan Sulchan Sofoewan
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 31, No 02 (1999)
Publisher : Journal of the Medical Sciences (Berkala Ilmu Kedokteran)

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Background: The management of premature rupture of the membrane (PROM) is one of the most controversial areas in obstetrics. In the case of full term PROM, the obstetrician is often faced with either immediate induction of labor with higher incidence of caesarean section or awaiting spontaneous labor with higher incidence of chorioamnionitis.Objective: To compare pregnancy outcomes between active management (AM) and conservative management (CM) in full term PROM.Methods: The study was carried out in randomized controlled trial at the Department of Obstetrics and Gynecology, Faculty of Medicine, Gadjah Mada University/Sardjito Hospital Yogyakarta. Sixty full term PROM cases admitted to the hospital between July-December 1994 were randomly allocated into AM (n=30) and CM (n=30).Results: Caesarean section rate due to the failure of induction among AM group was significantly higher than those in CM group (p= 0.03). Maternal and perinatal infection were not statistically significant (p>0.50). The total number of newborn babies with asphyxia was higher in AM group but no statistical significant difference was found (p> 0.50).Conclusion: The conservative management of full term PROM was better compared to active management, especially when the outcome is caesarean section rate due to the failure of induction:Key words: PROM - active management - conservative management.
The electroencephalography of chronically headache patients in Sardjito General Hospital, Yogyakarta Sri Sutarni Sri Sutarni
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 22, No 01 (1990)
Publisher : Journal of the Medical Sciences (Berkala Ilmu Kedokteran)

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Abstract

One hundred seventy four cases of 9 - 63 year old patients with chronical headache were reported. One hundred and twelve cases (64.37%) were examined by electroencephalography from April 1, 1986 to March 31, 1987, The EEG of 51 (29.31%) patients were normal, 44 (25.29%) with irritation pattern and 17 (9.77%) with hypofunction.It is suggested that the irritation pattern in chronical headache needed more attention in order to know the etiology and the location of intracranial lesion.Key Words: chronical headache - electroencephalography - irritation pattern - intracranial lesion - slow wave focus
Bahasa Indonesia Kedokteran Anonim Anonim
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 26, No 03 (1994)
Publisher : Journal of the Medical Sciences (Berkala Ilmu Kedokteran)

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Kata Kunci: Bahasa Indonesia - Kedokteran

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