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Journal of the Medical Sciences (Berkala Ilmu Kedokteran)
Published by Universitas Gadjah Mada
ISSN : 01261312     EISSN : 23563931     DOI : http://dx.doi.org/10.19106/JMedSci005303202101
Core Subject : Science,
Immunology & microbiology Neuroscience
Journal of the Medical Sciences (JMedSci) or Berkala Ilmu Kedokteran (BIK) is an international, open-access, and double-blind peer-reviewed journal, published by Faculty of Medicine, Public Health and Nursing, Universitas Gadjah Mada Yogyakarta Indonesia. JMedSci aiming to communicate high-quality articles in the areas of biomedical science from basic to clinical sciences.The journal welcomes papers from original articles, case reports, reviews, and book reviews. All papers published in JMedSci are freely available as downloadable pdf files. The journal began its publication on March 1973 and published quarterly (January, April, July, and October). JMedSci is abstracted and indexed in DOAJ, Crossref, Google Scholar, Sinta, Indonesia One Search. JMedSci is accredited by Directorate of General Higher Education, the Ministry of Research, Technology, and Higher Education, Indonesia
Arjuna Subject : Kedokteran - Kedokteran (Lain-Lain)
Articles 2,170 Documents
 148   149   150   151   152 
The effect of extract andropogon zizanioides urban roots as a repelent to Aedes Aegypti mosquito Mahardika Agus Wijayanti Mahardika Agus Wijayanti
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 29, No 03 (1997)
Publisher : Journal of the Medical Sciences (Berkala Ilmu Kedokteran)

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Abstract

Dengue haemorrhagic fever (DHF) is one of the viral infections transmitted by mosquitoes that still remains a health problem in Indonesia. Attempts to overcome this disease through experimental studies, in order to get rapid and right diagnosis, specific treatment and vaccine development have not been satisfactory. The main vector of DHF are Aedes aegypti and Aedes albopictus mosquito. Self protection againts mosquito bites could be done by using repelent. Lorosetu (Andropogon zizanioides urban) is a plant belonging to one family of fragrant grass, usually used as a soap fragrance or supplementary medication. Its root is commonly used to chase insect In the wardrobe. The aim of this study was to Investigate the effect of A. zizanioides Urban extract as a repelent to A. aegypti mosquito in the laboratory. In this study, time series observation using various concentration of extract A. zizanioides Urban as a repelent to A. aegypti was done. The result analized by Spit-plot and T-test showed that 25% extract of A. zizanioides Urban roots has the effect as a repelent within one hour, while the 50% and 100% concentration have the effect within two hours.Key words: Dengue Haemorrhagic Fever - Aedes aegypti - root extract - Andropogon zizanioides Urban root - repellent
The role vitamin-C on phagocytosis of macrophage on C. albicans. Melok Tin Melok Tin
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 37, No 02 (2005)
Publisher : Journal of the Medical Sciences (Berkala Ilmu Kedokteran)

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Abstract

Background: Several studies reported that vitamin-C can enhance immune response, including phagocytosis response on bacteria and virus. However at present there are only a few studies about the role of vitamin-C in phagocytosis response on fungi.Objectives: To determine the role of vitamin-C on macrophage phagocytosis on C. albicans.Methods: Ten ml blood was taken from healthy subject. Buffy coat containing monocytes was separated from the red-blood cells. After plating the mononuclear cells on the coverslip glass, the cells other than monocytes were washed out by tripsinization. The monocytes were treated with several doses of vitaminC i.e. 200 mg/mL, 100 mg/mL, 50 mg/mL, and 0 mg/mL as placebo. And then Candida suspension was added to the cells, stained PAS and HE counterstain. The result of macrophage phagocytosis activity was interpreted by counting intracellular Candida spores and was analyzed using one way ANOVA.Result: There is a high significant difference in the. number of intracellular candida spores, between vitamin-C 200 mg/mL compared to placebo (p<0.000); and there wasn't significant difference between 100mg/mL (p=0.064) and 50 mg/mL (p=0.709) compared to placebo.Conclusion: The dose of 200 mg/mL vitamin-C could increased macrophage phagocytosis activity on C.a/bicans significantly (p<0.01) compared to other doses. Key word: phagocytosis - macrophage - vitamin-C - C. a/bicans
Pro-inflammatory cytokine level and neutrophil count in acute ischemic stroke Suroto Suroto
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 34, No 02 (2002)
Publisher : Journal of the Medical Sciences (Berkala Ilmu Kedokteran)

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Abstract

Background: Pro-inflammatory cytokines are cytokines which are often found to be increased in an inflammatory process. In acute ischemic stroke there is an inflammatory response which affects the progress of the stroke.Objectives: The aim of this study was to understand the correlation between pro-inflammatory cytokines and neutrophil count in the peripheral blood of acute ischemic stroke patients.Methods: Peripheral blood was taken from 30 acute ischemic stroke patients age 50-70 years old on the third day of stroke attack. Leukocytes and differential count were examined, also level of TNF alpha, IL-1 and IL-8. Confirmation of ischemic stroke was determined by the head CT scan without contrast media on the fourth day of stroke attack. Thirty subjects without stroke were taken as control, with matching in age, gender and ethnic group.Results: The result showed a significant difference in neutrophil count between stroke group and control group (F 0.001). There was also significant difference among the 3 pro-inflammatory cytokines in 2 groups (F for TNF alpha: 0.007, IL-1: 0.055 and IL-8: 0.002). In bivariate correlation test, there was a significant correlation between IL-8 level and neutrophil count in the blood (p 0.0000).Conclusion: It is concluded that pro-inflammatory cytokines especially IL-8 has a role in recruiting neutrophil as an important component in the inflammatory response in acute ischemic stroke.Keywords: ischemic stroke - pro-inflammatory cytokines - IL-8 - neutrophil - correlation
Penile granuloma caused by liquid silicone injection Ishandono Dachlan Ishandono Dachlan
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 39, No 01 (2007)
Publisher : Journal of the Medical Sciences (Berkala Ilmu Kedokteran)

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Abstract

Various alloplastic injectable implants have been developed for soft tissue augmentation withoutsurgery. Silicone is a polymer from a family of chemically related organo-silicone compounds that mayexist in any state from a fluid to a solid. Injectable liquid silicone has been used for various cosmetictreatments, mainly for soft tissue augmentation, for example lip, cheek, breast, buttock, and penile. Liquidsilicone has been implicated in variety of adverse inflammatory reactions, sometimes resulting in tissuedestruction.We describe an adverse granulomatous reaction after the injection of liquid silicone for penile augmentation.Penile granuloma can occur as an adverse effect of penile enlargement with the injection of high viscositysolution, like silicone (siliconoma), paraffin (paraffinoma), vaseline or mineral oil. Penile granuloma is arare case which needs an accurate management.We found 30-years old man that occurs 5 weeks after non medical injection of liquid silicone. Surgicalmanagement was done with an excision of the granuloma and round incision on the upper penile, exceptthe urethral part. There were no complications following the treatment. Histopathology examination showedthe appearance of silicone-like foreign body granuloma and fibrosis of the preputium. It is concluded that Injection liquid silicone for penile augmentation could cause adverse granulomatous. Surgical management can be done with an excision of the granuloma.Keywords: liquid silicone, penile granuloma, surgical excision.
Antifilarial Activity of Diethylcarbamazine in Brugia Pahangi Aedes Togoi Model Infection Sugeng Juwono Mardihusodo Sugeng Juwono Mardihusodo
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 25, No 01 (1993)
Publisher : Journal of the Medical Sciences (Berkala Ilmu Kedokteran)

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Abstract

Sejak tahun 1947 dietilkarbamasin (DEC) diketahui khasiatnya sebagai antifilarial. Penelitian lanjutannya :ebih banyak mengarah kepada khasiatnya sebagai mikrofilarisida dan makrofilarisida pada Venebrata. Kejelasan aktivitas DEC terhadap stadia perkembangan cacing filaria dalam nyamuk Vektomya sangat sedikit diketahui, yang sebenamya juga penting untuk mengungkap makna obat itu dalam pengendalian penularan filariasis. Penelitian ini bedujuan untuk mengungkap lebih rind tentang daya DEC sebagai filarisida pada nyamuk Acdcs togoi yang diinfeksi dengan Brttgia pahangi.Penelitian dilaksanakan dengan memberikan pakan secara langsung kepada Ae. togoi yang dikolonisasi dengan larutan DEC dalam air sukrose 10% dengan konsentrasi 200, 100, 50 dan 0 mg%. Angka modalitas (AM), angka infeksi (Al), angka infektif (Alm), jurnlah larva per nyamuk terinfeksi (JUN), jumlah larva infektif per nyamuk terinfeksi (JL1PN), perlyebaran larva B. pahangi dalam tubuh nyamuk, dan ukuran (panjang badan) larvae, setelah nyamuk Ae. togoi dikolonisasi selama 12 hari setelah pemberian pakan darah infeks dan kucing yang terinfeksi B. pahangi, di tetapkan.Pedambahan AM nyamuk Ae. togoi yang tanpa maupun dengan infeksi B. pahangi tidak bermakna, dan tidak bergantung kepada konsentrasi DEC, menunjukkan bahwa DEC tidak bersifat insektisidal. Perbedaan di antara AM nyamuk tanpa dan dengan infeksi filarial diduga karena daya merusak filaria parasit selama perkembangan dan migrasi dalam tubuh nyamuk.Al dan Aln nyata menurun pada had ke 12. Larva H (U) B. palzangi masih ditemukan dalam tubuh Ae. togoi yang diberi pakan larutan DEC selama 12 hari; hal ini mengesankan bahwa DEC menghambat perkembangan sebagian larvae B. pahangi. Selama 12 hari persentase larvae B. pahattgi di bagian kepala nyamuk Ae. togoi nyata lebih rendah daripada yang pada nyamuk pembanding; hal ini menunjukkan hahwa DEC juga menghambat migrasi sebagian larvae filaria. Disimpulkan hahwa DEC nyata berIchasiat parsial sebagai anti filarial pada infeksi model B. pahangi - Ae. togoi.Key Words: diethylkarbamazine B. pahangi Ae. togoi insecticidal effect inhibitory effect
Filariasis klinis yang disebabkan oleh Brugia malayi nonperiodik pada penduduk asli Dayak di Kalimantan Timur Fransiskus Asisi Sudjadi Fransiskus Asisi Sudjadi
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 28, No 04 (1996)
Publisher : Journal of the Medical Sciences (Berkala Ilmu Kedokteran)

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Abstract

Keyword : Brugia malayi -- nonperiodic form -- filarial attack -- elephantiasis -- lymphatic filariasis
Diabetes mellitus type 1 in congenital rubella syndrome: a case report Carina Lisa Madarina Julia E.S. Herini
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 40, No 04 (2008)
Publisher : Journal of the Medical Sciences (Berkala Ilmu Kedokteran)

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Abstract

Corina Lisa, Madarina Julia, E.S. Herini . Diabetes Mellitus Type 7 in Congenital Rubella SyndromeDiabetes mellitus type 1 has been reported as a very rare delayed manifestation of congenital rubella syndrome. We reported a confirmed case of congenital rubella syndrome that developed diabetes mellitus at the age of seven years. The girl had been complaining of diabetes symptoms since six months before admission, but had been misdiagnosed. The patient finally came with symptoms of diabetic ketoacidosis, a life threatening complication of diabetes mellitus. Diabetes mellitus type 1 as a delayed manifestation of congenital rubella syndrome has to be kept in mind to prevent missing the diagnosis.Key words: rubella infection - congenital rubella syndrome - diabetes mellitus type 1ABSTRAKCorina Lisa, Madarina Julia, E.S. Herini - Diabetes Mellitus Tipe 7 pada Sindroma Rubella KongenitalDiabetes melitus adalah salah satu manifestasi lambat sindrom rubella kongenital yang jarang, tetapi perlu diwaspadai. Kami melaporkan satu kasus sindrom rubela kongenital yang mengalami diabetes melitus tipe 1 pad a usia 7 tahun. Meskipun gejala diabetes telah dikeluhkan sejak enam bulan sebelum masuk rumah sakit, penyakit diabetes tetap tidak terdiagnosis. Penderita akhirnya datang dengan gejala dan tanda ketosidosis diabetikum, suatu komplikasi diabetes mellitus yang mengancam jiwa. Manifestasi lambat sindrom rubella yang berupa diabetes mellitus tipe I harus diwaspadai untuk mencegah tidak terdiagnosanya penyakit tersebut.
Blokade Jantung Total pada Anak A. Samik Wahab A. Samik Wahab
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 21, No 01 (1989)
Publisher : Journal of the Medical Sciences (Berkala Ilmu Kedokteran)

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Abstract

The diagnosis of complete heart block is based on electrocardiogram. There would be few or even no cases missed if electrocardiograms were made of all slow heart rate infants and children. The history, physical signs, and X•ray would lead to the recognition of congenital and acquired complete heart block as an isolated, uncomplicated, anomaly. Incomplete history in healthy asymptomatic older children may cause difficulty in differentiating congenital or acquired origin.The conduction defect is usually discovered accidentally in healthy, asymptomatic children. Adams-Stokes syncopes rarely happen, even in the young. An obstetrician may detect a slow fetal heart rate, in which fetal electrocardiography and echocardiography have diagnostic value. A history of maternal lupus (SLE) or collagen disease or connective tissue disease (CTD) is another-major important diagnostic. The arterial pulse is very slow, the pulse amplitude wide and rhythm regular, The jugular venous pulse is intermittent cannon waves due to independent A waves which are asynchronous with and more rapid than the carotid pulse.The diagnosis is confirmed by electrocardiogram, the P waves and QRS complexes have no constant relation. The QRS duration is normal if the heart beat is initiated high in the His bundle and prolonged if the pacemaker is located below it.The treatment is directed especially to Adams-Stokes syncope. Digitalisation and other anticongestive measures may be indicated if cardiac failure occurs. In patients with recurrent Adams•Stokes attacks, resting ventricular rate of 40 beats per minute or less probably should be paced.The prognosis for congenital and acquired heart block is usually favourable.Key Words: heart block -- a-v block -- congenital heart disease -- acquired heart disease --rheumatic heart disease
Malabsorpsi zat besi dalam anemia defisiensi besi D. M. Mackay D. M. Mackay
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 9, No 02 (1977)
Publisher : Journal of the Medical Sciences (Berkala Ilmu Kedokteran)

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Abstract

keywords: anemia, sprue, tropical enteropathy, absorpsi zat besi,
Reference value of quantitative. examination of urine sediment using Shih-Yung (S-Y) system Riadi Wirawan Riadi Wirawan
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 36, No 3 (2004)
Publisher : Journal of the Medical Sciences (Berkala Ilmu Kedokteran)

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Abstract

Background: Conventional urine sediment examination was reported semiquantitatively, Shih-Yung system was quantitative and standaridizeci method.Objective: To evaluate urine sediment examination using Shih-Yung systems and to determine the reference value.Material and methods: Normal and pathologic urine from patients who have renal and urinary tract disorders, control material for urine microscopic examination Kova-TrolTm I and also urine from 120 healthy men and 120 healthy women.Results: Within run precision using normal urine, pathologic urine, and Kova-TrolTm I yielded a different coefficient of variation (CV) for small and large amount urine sediment component. Laboratory agreement between two observer using Kappa test were >80% for each urine sediment component. Reference values of urine sediment component were as follows: red cells 0-2/4, white cells 0-4/4, hyalin cast 0/ pL, epithelial cell for men 0-1/4 and epithelial cell for women 0-9/4.Conclusion: a relative big CV for small amount urine sediment component and vice versa. Reference values of urine sediment component were as follows: red cells 0-2/4, white cells 0-4/4, hyalin cast 0/epithelial cell for men 0-1/4 and epithelial cell for women 0-9/4. Shih-Yung system yielded a good laboratory agreement between two observers using Kappa test.Key words: urinalysis - urine sediment - quantitative examination - S-Y system - normal value

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