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Journal of the Medical Sciences (Berkala Ilmu Kedokteran)
Published by Universitas Gadjah Mada
ISSN : 01261312     EISSN : 23563931     DOI : http://dx.doi.org/10.19106/JMedSci005303202101
Core Subject : Science,
Immunology & microbiology Neuroscience
Journal of the Medical Sciences (JMedSci) or Berkala Ilmu Kedokteran (BIK) is an international, open-access, and double-blind peer-reviewed journal, published by Faculty of Medicine, Public Health and Nursing, Universitas Gadjah Mada Yogyakarta Indonesia. JMedSci aiming to communicate high-quality articles in the areas of biomedical science from basic to clinical sciences.The journal welcomes papers from original articles, case reports, reviews, and book reviews. All papers published in JMedSci are freely available as downloadable pdf files. The journal began its publication on March 1973 and published quarterly (January, April, July, and October). JMedSci is abstracted and indexed in DOAJ, Crossref, Google Scholar, Sinta, Indonesia One Search. JMedSci is accredited by Directorate of General Higher Education, the Ministry of Research, Technology, and Higher Education, Indonesia
Arjuna Subject : Kedokteran - Kedokteran (Lain-Lain)
Articles 2,170 Documents
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The examination of corneal curve in refractive anomaly A. Soemarsono A. Soemarsono
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 16, No 01 (1984)
Publisher : Journal of the Medical Sciences (Berkala Ilmu Kedokteran)

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Abstract

The corneal curvature is an important medium refractum because it gives the strongest refraction.The measurement of corneal curve has a direct connection with refraction. The measurements of the emmetropic, myopic, hypermetropic and astigmatic cornea have been presented. The mean of the emmetropic cornea! curve was 42.796 D, that of the myopic was 44.275 D. Statistically, there was significant difference between those of emmetropic and myopic cornea.The mean curve of hypermetropic eyes was 42.843 D. However, statistically there was no difference between the emmetropic and hypermetropic corneal curve.In astigmatism there were always differences between the vertical and horizontal curves. Key Words: corneal curve - emmetropy - myopy - hypermetropy - astigmatism
Beberapa Segi Klinik Mengenai Bell's Palsy di Bagian Neurologi Rumah Sakit Universitas Gadjah Mada Boedi Sarojo Boedi Sarojo
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 8, No 01 (1976)
Publisher : Journal of the Medical Sciences (Berkala Ilmu Kedokteran)

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Abstract

Selama periode Januari 1975 sampai dengan Desember 1975 kami kumpulkan 39 penderita dengan paralise facialis perifir dari seluruh penderita baru 747 orang yang datang berobat ke Rumah Sakit Pugeran Bagian Neurologi Eakultas Kedokteran Universitas Gadjah Made. Mereka terdiri dari 27 pria (69,2%) dan 12 wanita (30,8%). Umur penderita berkisar antara 1 tahun sampai 60 tahun, dengan rata-rata terbanyak sekitar umur 20 — 40 tahun (58;9%).Dari 39 kasus paralise facialis perifir yang terkiimpul atau terseleksi terdapat 25 Bell's palsy atau 64,1 %: Penyebab lain seperti hypertensi 5 orang ( = 12,8%), meningitis pada anak-anak sebanyak 3 orang (7,7%), otitis media 2 orang (5,1%), trauma 2 orang (5,1%), mastoiditis 1 orang (2,5%) dan tumor cerebri 1 orang (2,5%).Sisi wajah muka yang terkena paling banyak adalah sebelah kanan, yaitu sebesar 61,5%. Tempat lesi yang paling banyak terletak di daerah distal foramen stylomastoideum, yaitu sebesar 69,2%.Penderita Bell's palsy yang diobati akan sembuh pada minggu ke 2 — 4. Penderita paralyse facialis perifir lain antara lain 3 orang untuk observasi hypertensi (kiriman dari Bagian Penyakit Dalam), 1 dengan postmeningitis (kiriman dari Bag. Kanak-kanak) dan 1 dengan tumor cerebri (kiriman dari Bagian Mata, dengan visus jelek tanpa bisa dikon-lcsi) tidak dapat kami ikuti mengingat mereka tidak kembali setelah minggu ke 4 tanpa alasan.Semua penderita kimi beri terapi antibiotika, prednison, nicotinamide, vitamin neurotropik, dan beberapa ada yang kami beri salyci:ar. Bagi yang ada faktor etiologisnya kami beri terapi kausal, kecuali untuk tumor cerebri kami tambahkan terapi simptomatis.Lokal pada wajah muka kami beri penyinaran dengan inframerah, massage ringan - stimulasi dengan arus faradis/galvnis, ini diberikan dap 2 hari sekali. Di rumah penderita melakukannya sendiri dengan mengompres air hangat dan massage ringan selama 5 — 10 menit 3 kali sehari, sedang untuk matanya diberi tetesan acid boric 3% dan memakai kacamata teduh apabila ingin keluar rumah.Dari sejumlah 39 penderita ternyata 25 orang (64,1 %) mengalami penyembuhan dalam 4 minggu pertama dan 32 orang (82,05%) mengalami sembuh sempurna. Kami tidak menjumpai kontraktur sebagai satu-satunya gejaia sisa (sequela) penyakit ini.Ditemukan 2 pria yang menderita Bell's palsy untuk kedria kalinya, pada sisi yang bertentangan dengan yang terdahulu.
Serologic test vs antigenemia assay as diagnostic marker for cytomegalovirus infection in children. Agnes Yunie Agnes Yunie
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 34, No 04 (2002)
Publisher : Journal of the Medical Sciences (Berkala Ilmu Kedokteran)

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Abstract

Objective: To determine the level IgG and IgM anti-CMV in children clinically suspected to be infected by Cytomegalovirus (CMV) and to determine the diagnostic value of IgG dan IgM anti-CMV as diagnostic tools for active CMV infection with antigenemia assay as the gold standard.Material and methods: Diagnostic test, observational cross sectional study. All children suspected to have CMV infection who were hospitalized or who visited neurology outpatient clinic in Sardjito Hospital in March 1" - September 11" 2002 were enrolled in this study. Serologic test for IgG and IgM anti-CM- and antigenemia assay were conducted to confirm the diagnosis of active CMV infection.Results: Nine of 82 specimens (12%) were confirmed to have active CMV. The cut off point of IgG was 265.75 AU/ml, with the sensitivity, specificity, positive predictive value (PPV) and negative predictive value (NPV) of 67% (95% CI: 31-91%), 70% (95% CI: 58-80%), 21% (95% CI: 9-42%), 94% (95% CI: 84-99%), respectively, and likelihood ratio (LR) 4.5. The cut off point of IgM was 0.445, with the sensitivity, specificity, PPV and NPV of 56% (95% CI: 23-85%), 67% (95% CI: 55-77%), 17% (95% CI: 7-37%) and 93% (95% CI: 81-98%), respectively and LR 1.7. There was no significant relation between the level of IgG or IgM above cut off point and antigenemia (p=0.06 and p =0.27). Level of IgG combined with IgM had a significant relation with antigenemia (p 0.04), with the sensitivity 75% (95% CI: 22-99%), specificity 81% (95% CI: 66-91%), PPV 27% (95% CI: 7-61%), NPV 97% (95% CI: 84100%) respectively. LR was 5.3. Most of the children (40 patients) had psychomotor disorder (60%). There was significant relation between trombocytopenia and antigenemia (p =0.04).Conclusions: An increased level of IgM combined with IgG above cut off point is a significant diagnostic tool for active CMV infection. Psychomotor disorder is the clinically sign mostly found in active CMV infection. Thrombocytopenia can be used to detect active CMV infection.Key words: active CMV infection - antigenemia - IgM & IgG anti-CMV - IgM anti-CMV - diagnostic test
Secondary transmissions of filariasis caused by nonperiodic form of Brugia malayi among indigenous Dayak people in East Kalimantan FA.Sudjadi FA Sudjadi
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 31, No 02 (1999)
Publisher : Journal of the Medical Sciences (Berkala Ilmu Kedokteran)

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Abstract

Background: Nonperiodic or aperiodic form of Brugia malayi Lichtenstein was discovered and reported recently from East Kalimantan as a new subspecies by Sudjadi, in addition to the nocturnally periodic and subperiodic form, previously known as health problem in many rural areas in Indonesia. The Brugia type was found in high endemicity among Dayak indigenous people who were growing paddy rice by shifting cultivation method in the forest areas in Krayan village, Long Ikis district, Pasir regency.Objectives: To detect secondary transmissions, which so far known unusually happenned on filarial elephantiasis, in the highly endemic of Krayan village, when previous infections have already ceased by entering the chronic stage.Method: Krayan villagers suffering from elephantiasis during previous clinical examinations were recruited in the study. Blood samples (in an amount of 60 mm3) were taken from finger prick to examine the presence of microfilariae.Results: Amount of 17 elephantiasis cases of local inhabitants were examined. Most of them, ie 11 people or 64.7%, were found positif with microfilaremia, with the highest densities of 151 microfilariae per 60 mm3 blood. These unusual cases of secondary transmissions were not only closely related to the high endemicity of filariasis in that Krayan area, but the effective transmissions originated from wild animals in the forest as source of infections as well.Conclusion: The secondary transmissions of filariasis found among indigenous Dayak people in Krayan clearly supports the nonperiodic or aperiodic form of B. malayi filarial worm to be zoonotic or sylvanic.Key words: nonperiodic form of Brugia malayi - elephantiasis - microfilaremia - secondary transmissions -sylvanic filariasis
The right to die: Its biomedical aspects Teuku Jacob Teuku Jacob
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 22, No 02 (1990)
Publisher : Journal of the Medical Sciences (Berkala Ilmu Kedokteran)

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Abstract

This article discussed the existence or non-existence of the right to die. Death has various facets, namely the biomedical, social, historical, moral and religious. Man has the right to live or not to be killed, but not the reciprocal right to die or to kill, although in borderline cases this is debatable. The right to die is executed by way of suicide and voluntary euthanasia.Suicide is committed due to hopelessness, shame or guilt feeling, terminal illness, loyalty to a dead person, and for political reasons. It can be performed by an individual, a pair (suicide pact), a family, a group or en masse. The medical profession should prevent all suicidal attempts and help the surviving victim, since it is its duty to prolong life and ameliorate suffering.Euthanasia is either positive or negative (not infrequently, and inaccurately, termed active or passive), voluntary or involuntary, direct or indirect, and by not implementing extraordinary or ordinary procedures in life saving. Reasons are put forward why euthanasia is condoned or condemned. The moral difference between the two forms of euthanasia are questioned by some serious ethicists. Conditions for negative euthanasia are presented if it is performed selectively, for which the demand is unfortunately real.Key Words: right to die-euthanasia-suicide-patient rights - bioethics
The ethics of scientific research T. Jacob T. Jacob
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 13, No 04 (1981)
Publisher : Journal of the Medical Sciences (Berkala Ilmu Kedokteran)

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Abstract

Considering the importance of scientific ethics in research, especially if it involves human experimentation, the author discUsses various ethical points in conducting research from the preparation of research until the publication of its results. Emphases are placed upon responsibility CO the source of information, colleagues, research material, both human and animal, and humanity at large; scientific objectivity; and intellectual honesty.The need for research ethics cannot be overemphasized since deviation from the ethical principles are currently occurring even in the scientifically most advanced countries, due to, among others, the ''publish or perish" principle, pressure from funding agencies and research institutions, professional rivalries between individuals or institutions, and fights for priorities of discoveries and inventions.In the less developed countries the deviations are more elementary, but with the increasing quantity of research, complex problems are making their debut.Key Words: scientific ethics - human experimentation - informed consent - research review board - scientific objectivity
Nutritional status, growth, dietary intake in asthmatic children: a study to Junior High Schools in Yogyakarta municipality. Elisa Elisa
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 34, No 02 (2002)
Publisher : Journal of the Medical Sciences (Berkala Ilmu Kedokteran)

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Abstract

Objective: To know the relationship between asthma and nutritional status, growth, and dietary intake. Design: Prospective cohort study of children aged 12-18 years.Setting: Twenty eight Junior High Schools in Yogyakarta municipality.Subjects: There were 802 children who ever had symptoms of asthma and children who never had asthma as control. Questionnaire was used to establish the diagnosis of asthma. Subjects were grouped as: 1) ever had symptom of asthma but not in the last 6 months; 2) ever had 1 symptom of asthma in the last 6 months; 3) ever had 2 symptoms of asthma in the last 6 months; 4) ever had 3 symptoms of asthma in the last 6 months; and 5) never had asthma.Main outcome measures: Z-score for weight for age and height for age, body mass index (BMI), and dietary intake.Results: This study revealed there was no statistical difference between asthmatic group and control group in nutritional status based on weight for age in the first measurement (p=0.292), the second (p=0.258), and the third (p=0.122); based on height for age, in the first measurement (p=0.356), the second (p=0.541), the third (p=0.384). Likewise, based on body mass index, in the first measurement (p=0.335), the second (p=0.305), the third (p=0.166). Concerning growth there was no statistical difference between asthmatic group and control group based on weight for age from the first to the second measurement (p=0.215), second to third Ip=0.866), first to third (p =0.188); based on height for age from the first to the second measurement Ip=0.774), second to third (3=0.627), first to third (p=0.738. Likewise, based on body mass index from the first to the second measurement (p=0.556), second to third (p=0.913), first to third (p=0.784). Daily intake of nutrition revealed there was no statistical difference between asthmatic group and control group concerning calorie (p=0.075), protein (p=0.345), fat (p=0.989), carbohydrate (p=0.731), calsium (p=0.936), iron (p=0.566), vitamin A (p=0.457), vitamin B (p=0.932, and vitamin C (p=0.837).Conclusion: Asthma did not affect nutritional status, growth, and dietary intake. There was no significant difference on growth among study groups.Key words: asthma - nutritional status - growth - dietary intake
Pengobatan Asthma Bronchiale Dan Pemakaian Corticosteroid Samekto Wibowo Samekto Wibowo
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 6, No 03 (1974)
Publisher : Journal of the Medical Sciences (Berkala Ilmu Kedokteran)

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Abstract

Survai mengenai tempat perkembang-biakan nyamuk Aedes aegypti di Daerah Istimewa Yogyakarta telah dilakukan oleh Bagian Parasitologi Fakultas Kedokteran dan Fakultas Biologi Universitas Gadjah Mada pada tgl. 27 Maret sampai dengan 30 April 1973.Dari hasil survai ternyata bahwa nyamuk Aedes aegypti lebih banyak bersarang di kota daripada di pedesaan. Hampir 100% dari desa atau kampung di mana terdapat penderita suspect D. H. F. terbukti positip Aedes aegypti. Nyamuk ini kebanyakan berkembang biak dalam tempayan (di dalam rumah lebih banyak daripada di luar rumah) dan hanya sedikit di pot-pot bunga ataupun di lobang-/obang pohon; jadi tidak seperti sifat aselinya.Dengan laporan di atas ini diharapkan agar penanggulangan penyakit D. H. F., khususnya pemberantasan vektor Aedes aegypti dapat berhasil dengan memuaskan.
Liver Function Test in Chronic Hemodialyzed Patients with Anti Hepatitis C Virus Antibody Mochammad Sja'bani Mochammad Sja'bani
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 26, No 02 (1994)
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Abstract

Untuk mengetahui fungsi hepar pada penderita gagal ginjal terminal dengan antibodi terhadap virus hepatitis C (anti HCV) positif yang menjalani hemodialisis, suatu penelitian potohOlintang telah dilakukan di Unit Hemodialisis. Rurnah Sakit Umum Pusat Dr: Sardjito, Yogyakarta.Selama penelitian ditemukan 58 penderita (42 laki-laki. 16 perempuan) dengan 32 (55%).anti HCV positif. Tidak ditemukan perbedaan yang bermakna antara kelompok dengan anti HCV positif dan kelompok dengan anti HCV negatif dalam kadar aspartate amino transferase (AST) (46,22 ± 20,85 UI/1 vs 40,15 ± 20,37 U1/1, p > 0,05), kadar alanine amino transferase (ALT) (45,44 ± 26,26 IU/1 vs 37,04 ± 23,03 U1/1, p > 0,05), kadar alkaline phosphatase (ALP) (156, 31 ± 141,141U/1 vs 144,57 ± 82,15.1y/l, p > 0,05),. dan jumlah hemodialisis (8 sampai dengan 733 kali). Kadar AST yang rneningkat di afas 1,5 kali nilai normal cenderung ditemukan lebih besar tapi secara statistik tidak signifikan pada kelompok dengan anti HCV positif dibanding dengan kelompok dengan anti HCV negatif (56.0% vs 30,7%, p > 0,05) yang mungkin akibat jumlah sampel yang kecil. Frekuensi transfusi ditemukan lebih tinggi secara bermakna pada kelompok dengan anti HCV positif dibanding kelompok dengan anti HCV negatif (3,53 ± 3,47 vs 2,23 ± 1,47 kali, p < 0,05).Key Words : hepatitis C virus-anti HCV antibodies -end stage renal disease-blood transfusion- hemodialysis
Neovascular glaucoma following central retinal vein occlusion - a case report Budihardjo Budihardjo
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 30, No 01 (1998)
Publisher : Journal of the Medical Sciences (Berkala Ilmu Kedokteran)

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Abstract

Glaucoma is an Important cause of blindness, in particular neovascular glaucoma which is a complex condition and always becomes challenging for the clinician in the past, present and the future. A 54-year-old man suffering from blindness of neovascular glaucoma following central retinal vein occlusion in the right eye with no response to Pan Retinal Photocoagulation (PRP) and open angle glaucoma in the left eye has been reported. Systemic conditions as a predisposing factor were not found, so the local ocular background i.e open angle glaucoma was suspected to be the cause of central retinal vein occlusion. In this case the management must be focused on the left eye to avoid further complication. The right eye was on end stage and no response to PRP and the visual acuity Is no light perception (NLP). Enucleation should be considered as the high intraocular pressure (IOP) and ocular pain persisted.Key words: neovascular glaucoma - central retinal vein occlusion - open angle glaucoma - Pan retinal photocoagulation

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