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Journal of the Medical Sciences (Berkala Ilmu Kedokteran)
Published by Universitas Gadjah Mada
ISSN : 01261312     EISSN : 23563931     DOI : http://dx.doi.org/10.19106/JMedSci005303202101
Core Subject : Science,
Immunology & microbiology Neuroscience
Journal of the Medical Sciences (JMedSci) or Berkala Ilmu Kedokteran (BIK) is an international, open-access, and double-blind peer-reviewed journal, published by Faculty of Medicine, Public Health and Nursing, Universitas Gadjah Mada Yogyakarta Indonesia. JMedSci aiming to communicate high-quality articles in the areas of biomedical science from basic to clinical sciences.The journal welcomes papers from original articles, case reports, reviews, and book reviews. All papers published in JMedSci are freely available as downloadable pdf files. The journal began its publication on March 1973 and published quarterly (January, April, July, and October). JMedSci is abstracted and indexed in DOAJ, Crossref, Google Scholar, Sinta, Indonesia One Search. JMedSci is accredited by Directorate of General Higher Education, the Ministry of Research, Technology, and Higher Education, Indonesia
Arjuna Subject : Kedokteran - Kedokteran (Lain-Lain)
Articles 2,170 Documents
 68   69   70   71   72 
Seurge- Weber Disease: A case report Sri Sutarni, Sri Sutarni
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 15, No 03 (1983)
Publisher : Universitas Gadjah Mada

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Abstract

Sturge-Weber Disease is one of the congenital malforMations, in which we find naevus facialis, general or focal convulsion, mental retardation, and contralateral hemiparesis; sometimes also choroid angiomata, buphthalmus and glaucoma.Skull rbntgenology, a E. G. and cerebral angiography make the diagnosis clear.We reported on a boy, 5 years old, with Sturge-Weber Disease who came to the Hospital with convulsion.Key Words: Sturge-Weber Disease - congenital malfOrmation - naevus facialis - convulsion - mental retardation
Role of Vitamin C on the viabilitys of the keratinocyte and HeLa cell with irradiation of UVB ray. Iryani Andamari, Iryani Andamari
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 36, No 4 (2004)
Publisher : Universitas Gadjah Mada

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Abstract

Background:Ultraviolet B (UVB) exposure is one of the external factors which can cause reduction of cell viabillity through photochemistry reaction and can be managed using antioxydant. Failures of DNA repair and apoptosis have some important roles in photocarcinogenesis.Objective: This research is aimed to know the effect of vitamin C on the viability of UVB irradiated keratinocytes and HeLa cells.Method: This research employed a simple experimental method. Two groups of cells used in this research were: Group I normal foreskin keratinocytes passage III, and Group II HeLa cells. Each group was divided into 25 sub-groups consisting of 2x104 cells each, treated with vitamin C at 0, 6, 12, 40, 200 µg/ml concentrations, and UVB irradiated (Phillips UVB TL4OW/12RS) at 0, 200, 400, 800, 1600 mJ/cm2 intensities. Each treatment was done in quintet. Viable cells were determined based on formazan blue reaction using ELISA-reader 550 nm 24 hours after treatment. The results were analyzed by independent t-test, one-way ANOVA, and multivariate analysis using three-way analysis of variance,Result: Vitamin C at 6, 12, 40, and 200 ug/m1 concentrations significantly increased normal keratinocyte and HeLa cells viability which were not irradiated by UVB, statistically significant, compared to normal keratinocyte and HeLa cells which were not treated with vitamin C. HeLa cells, which were irradiated by UVB at 200, 400, and 800, 1600 mJ/cm2 intensities and treated with vitamin C at 6, 12, 40 and 200 ug/ ml concentrations, statistically significant in decreasing cell viability.Conclusion: Vitamin C at 200 µg/ml concentration, which was given to normal keratinocytes irradiated by UVB at 200, 400, 800, and 1600 mj/cm2 intensities used in this research showed its protection effect, thus enhancing the viability of the cell. Vitamin C 6, 12, 40 ug/ml, which were irradiated with UVB at 200, 400, 800, and 1600 mJ/cm2 intensities, did not show protection effect. HeLa cells were less resistant than normal keratinocytes to UVB irradiation at 200, 400, 800, and 1600 mj/cm2 intensities.Key words: vitamin-C, HeLa cell, keratinocyte, cell viability, UVB
Kapsula akteri dan Fungsinya Koesnijo, Koesnijo
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 6, No 04 (1974)
Publisher : Journal of the Medical Sciences (Berkala Ilmu Kedokteran)

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Abstract

- Kapsula adalah alat pelindung bakteri terhadap pengaruh luar yang merugikan dirinya, dan berakibat bersifat virulen.- Bakteri dalam kapsula bersifat aktif dan dapat berkembang biak, sedangkan dengan spora bakteri bersifat pasif saja.- Bakteri yang semula dianggap apathogen, kemungkinan penyebabnya dapat dicari pada adanya kapsula.- Kapsula juga dapat menimbulkan pembagian dalam type-type dari suatu jenis bakteri.
Insertion of Norplant ith and withoul prophylactic antibiotics: A randomized C011 ironed siudy Risanto Siswosudarmo, Risanto Siswosudarmo
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 24, No 01 (1992)
Publisher : Universitas Gadjah Mada

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Abstract

A randomized controlled study on the insertion of Norplant without prophylactic antibiotics had been carried out. The aim of the study was to compare the risk of complication happening shortly after insertion. A total of 500 acceptors completed their follow-up, 244 belonged to the antibiotic group (tetracycline), while 256 belonged to the control group. They come from suburban areas stuTounding the city of Yogyakarta.Insertion was carried out outside the hospital during the Safari Mass Campaign, with hospital standard asepsis. Follow-up was carried out one week after insertion to detect the presence of such complication or side effects as pain, inflammation, abscess and sense of itching. Data were processed with version 2.0 SPSS program using Nikon PC Computer. t-test, chi-square test and relative risk were statistical analysis used in the study.Results showed that both groups were comparable in. terms of age, body weight, parity, duration of insertion and level of education. The overall incidence of complication in the non-an tibiotic group was 19,9% compared to 24.2% in the antibiotic group (RRO.82, 95% CL 0.57– L19) . More detailed complications such as pain, inflammation, abscess and sense of itching show neither clinical nor statistical significant differences. The risk of complication in all, cases was influenced neither by duration of insertion nor by acceptors level of education.The study concluded that the insertion of Norplant without prophylactic antibiotics was as safe as with antibiotics.Key Words: Norplant - contraceptive mass campaign - antibiotics - obstetrics - contraceptive complication
Perubahan-Perubahan Dalam Pendidikan Kedokteran : Renungan, Ramalan dan Saran T. Jacob, T. Jacob
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 12, No 04 (1980)
Publisher : Journal of the Medical Sciences (Berkala Ilmu Kedokteran)

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Abstract

Kata kunci: Pendidikan Kedokteran
Pengujian kadar iodium total dalam urin dengan metode destruksi basah dan destruksi kering Iswani S, Iswani S
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 28, No 01 (1996)
Publisher : Universitas Gadjah Mada

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Abstract

Total iodine contents in the urine samples were directly tested with and without destruction using Ion Selective Electrode (ISE) method. The dry destruction was carried out with volume variation of 0.5 M NaOH solution and wet destruction was done with 4 ml of concentrated H2504 and 1 ml of concentrated HNO3 mixture, followed by volume variation of 1% p-aminophenol solution and temperature to reduce 103- form to form. The Chloride ion contents were also determined using technique. It was found that the optimum of NaOH amount, the optimum of 1% p-aminophenol and temperature (wet digestion) was 2 ml, 12 ml, and 60°C respectively. The chloride ion contents in 6 urine samples were in the range of 2373-4495 ppm and didnt interfere on r determination. The total r contents in the six samples without destruction,using wet and dry destructions were in the range of 280-392 ppb, 291-505 ppb and 306-516 ppb respectively. The t-test showed that the total Iodine content in urine samples with and without destructions was significantly different.Key words: Iodine - urine - ISE method - wet and dry destruction - chloride
The Role of the medical profession and its support system in the promotion of peace and the prevention of nuclear war Soedibjo Sardadi, Soedibjo Sardadi
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 18, No 04 (1986)
Publisher : Journal of the Medical Sciences (Berkala Ilmu Kedokteran)

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Abstract

In this article the author describes the present development of the war machine, and its actual and potential impact on medicine. The effects of nuclear explosion are briefly discussed and the possible roles of the medical profession is brought forth in facing the current global political situation. The ethical and moral foundation of medicine is emphasized in carrying out the professional social responsibility to preserve the comprehensive health of mankind. Key Words: prevention of nuclear war - peace studies - medical polemology - medical effects of nuclear explosion - war medicine
Vibrio parahaemolyticus di Yogyakarta Trihendrokesowo, Trihendrokesowo
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 10, No 02 (1978)
Publisher : Journal of the Medical Sciences (Berkala Ilmu Kedokteran)

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Abstract

Keyword : Vibrio parahaemolyticus
The Effect of budesonide on lymphoid and non-lymphoid cell profiles, and la-antigen expression in rats with experimental colitis Marsetyawan HNE Soesatyo, Marsetyawan HNE Soesatyo
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 27, No 01 (1995)
Publisher : Universitas Gadjah Mada

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Abstract

Kortikosteroid merupakan obat yang efektif terhadap peradangan, seperti penyakit peradangan usus kronis. Penelitian ini bertujuan untuk mengetahui pengaruh pamberian kortikosteroid lokal, yakni budesonide colitis experimental pada tikus, khususnya pengaruhnya terhadap populasi sel limfoid dan nonlimfoid, serta ekspresi antigen-la (molekul major histocompatibility complex (MHC) kias II). Di camping itu diteliti pula peran molekul-molekul adhesi, seperti intercellular adhesion molecules (iCAM-1) dan lymphocytes function associated antigen (LFA-1) setelah pemberian obat tersebut.Model colitis dibuat dengan pemberian secara intracolon zat hapten: 2,4,6-trinitrobenzene sulphonlc acid (TNBS) dalam etanol, berdasarkan metode standar. Obat budesonide diberikan deism deals tunggal dan ganda sebanyak 0,25 ml larutan 104 M secara lokal ke dalam colon dengan menggunakan kateter. Populasi sal limfoid dan nonlimfoid di sepanjang mukosa dan submukosa, termasuk plak Payer (PP) dan jaringan limfoid di daerah proksimal colon diperiksa dengan teknik imunositokimiawi. Ekspresi MHC Ida* ii dan molekul adhesi diteliti menggunakan panel antibodi monoklonal (AbMo).Dosis ganda budesonide (3x) *angst efektif untuk mengobati colitis akut; ini dapat diamati dad gejala-gejala klinis yang menghilang. Pemeriksaan histologik menunjukkan penurunan nyata jumlah subpopulasi makrofag, seperti sel EDI% ED2* dan ED3+. Intensitas ekspresi la dan ekspresi ICAM-1, LFA-1 mengurang, sdang lainnyaedangkan migrasi sal neutrofil dan sel radang lainnya menghilang.Key words : inflammatory bowel disease -- TNBS colitis -- budesonide-lymphoid and non-lymphoid cell populations -- MHC class II expression -- adhesion molecules.
Potential risk of adverse event in patients undergo elective urologic surgery Ratih Wulansari, Ratih Wulansari
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 37, No 03 (2005)
Publisher : Universitas Gadjah Mada

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Abstract

Background: Almost all medical treatment may pose risk. The risk of adverse event in patients undergoing surgery is higher than those who undergo non surgical intervention. The incidence of adverse event varies from 3.7% in the US to 16.7% in Australia. Basically, most of the adverse events are preventable. It is therefore recommended to implement clinical risk management in health care services. Objective: To identify risk of adverse event among patients undergo elective urologic surgeryMethod: A cross sectional study was carried out to collect prospective data on patients underwent elective urologic surgery at Tabanan General Hospital between August-September 2005. Data on the risk of adverse event were identified since patients were admitted to Hospital, underwent pre-op preparation and surgical procedure. Follow up was carried out until 30 days after surgical procedureResult: Seven major potential risks were identified, i.e.(1) pre-operative stay> 3 days (28.85%);(2) patients risks for surgery (44.23%); (3) prophylactic antibiotic were given > 2 hours before surgery (88.46%); (4) ASA > (82.69%); (5) preoperative hair removal > 2 hours before surgery (86.53%); (6) use of intravenous line more than 24 hours (26.92%); and (7) use of urine cathether > 6 days (25%). It is found that pre-operative stay > 3 days was significantly related to the occurrence of adverse event.Conclusion: Pre-operative stay > 3 days contributed significantly in the occurrence of adverse event among patients underwent elective urologic surgery. However, other risk factors were not significantly related to adverse event due to small sample size.Key words: elective urologic surgery - risk - clinical risk management - clinical governance 

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