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Journal of the Medical Sciences (Berkala Ilmu Kedokteran)
Published by Universitas Gadjah Mada
ISSN : 01261312     EISSN : 23563931     DOI : http://dx.doi.org/10.19106/JMedSci005303202101
Core Subject : Science,
Immunology & microbiology Neuroscience
Journal of the Medical Sciences (JMedSci) or Berkala Ilmu Kedokteran (BIK) is an international, open-access, and double-blind peer-reviewed journal, published by Faculty of Medicine, Public Health and Nursing, Universitas Gadjah Mada Yogyakarta Indonesia. JMedSci aiming to communicate high-quality articles in the areas of biomedical science from basic to clinical sciences.The journal welcomes papers from original articles, case reports, reviews, and book reviews. All papers published in JMedSci are freely available as downloadable pdf files. The journal began its publication on March 1973 and published quarterly (January, April, July, and October). JMedSci is abstracted and indexed in DOAJ, Crossref, Google Scholar, Sinta, Indonesia One Search. JMedSci is accredited by Directorate of General Higher Education, the Ministry of Research, Technology, and Higher Education, Indonesia
Arjuna Subject : Kedokteran - Kedokteran (Lain-Lain)
Articles 2,170 Documents
 70   71   72   73   74 
Physical aspects of a nuclear explosion Budi Santosa, Budi Santosa
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 22, No 03 (1990)
Publisher : Journal of the Medical Sciences (Berkala Ilmu Kedokteran)

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Abstract

This article describes the principles of nuclear power, the nature of the atomic bomb and its impact on the environment, including the climate and the resulting nuclear winter.The author also points out the effects of nuclear radiation to the living organisms, both immediate and delayed. In conclusion he emphasizes the importance of immediate cessation of nuclear tests, in the atmosphere, on the surface, submarine as well as underground, because otherwise kis bound to increase radioactivityin the environ men t which endangers future generations, even in countries which are not involved in nuclear testing.Key Words: nuclear explosion-nuclear physics- nuclear winter -radioactive fall-out-medical effects of nuclear war
Orotidylate decarboxylase from human brain A. Salam M. Sofro, A. Salam M. Sofro
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 10, No 03 (1978)
Publisher : Journal of the Medical Sciences (Berkala Ilmu Kedokteran)

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Abstract

Orotidylate decarboxylase dari otak manusia telah dimurnikan 8,5 kali dan diselidiki beberapa sifat-sifatnya. Diperoleh dua harga K m yaitu 3,3 uM dan 1,6 uM yang nampaknya berkaitan dengan bentuk oligomerik enzima tersebut. Enzima tersebut dihambat oleh 6-AzaUMP>XMP>UMP>GMP sedang derivat-derivat nukleotida yang lain hanya menunjukkan pengaruh hambatan yang lemah
The effect of Zingiber officinales active compounds against microfilariae Brugia malayi in Fells catus, L. Budi Mulyaningsih, Budi Mulyaningsih
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 27, No 02 (1995)
Publisher : Universitas Gadjah Mada

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Abstract

Zingiber officinale, Rosa is a well known plant which can be used for the treatment of various diseases, and has been reported as an effective medicinal plant against Dirofilaria immitis in animal. The volatile oil and the pungent of Zingiber officinale, Rosa have been effectively used against larvae stage 3 (L3) B. malayi in vitro study.This study was designed to investigate the effect of the volatile oil and the pungent of Zingiber officinale, Rosc. against microfilariae B. malayi in Fells catus, L..Antifilarial activity of the pungent compound (isolate 1) and the volatile oil were assayed in vivo.The results showed that the volatile oil had the most quantity (rendement 0,5 %) and its activity against microfilariae B. malayi was higher than that of isolate 1, but lower than that of the dietylacarbamasine drug.Key words: microfilariae - volatile oil - the pungent of medicinal plant - B. malayi - Felis caws L
Gnathostoma spinigerum and Human Gnathostomiasis Marsetyawan Soesatyo, Marsetyawan Soesatyo
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 17, No 01 (1985)
Publisher : Journal of the Medical Sciences (Berkala Ilmu Kedokteran)

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Abstract

G. spinigerum adalah sejenis Nematoda yang hidup sebagai parasit pada Carnivore seperti kucing, anjing, harimau dsb. Infeksi pada manusia banyak terjadi di kalangan masyarakat penggemar makan ikan air tawar mentah atau setengah matang, yang mengandung larva infektif G. spinigerumtingkat rig-a. Manusia merupakan incidental host, sehingga tidak memungkinkan perkembangan larva cacing menjadi bentuk dewasa, tetapi larva ini di dalam tubuh manusia dapat bermigrasi ke seluruh organ dan menimbulkan gejala-gejala penyakit yang berbeda-beda, tergantung pada organ apa yang terserang. lnfeksi G. spinigerum pada sistem saraf pusat umumnya bersifat fatal, dengan gejala khas myeloensefalitis eosinofilik. Sam ini belum ada obat yang bersifat efektif terhadap cacing Mi. Usaha menanggulangi penyakit ini hanyalah mencegah penyebaran dari second intermediate host ke manusia. Key Words: Cnathostoma spinigerum - fresh-water fish - CNS-gnathostomiasis -myeloencephalitis - Nematoda
Is organum subfornicale of Rattus norvegicus a neuroendocrine gland ? A morphological study using histochemistry and immunohistochemistry methods. Daryanto, Daryanto
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 26, No 02 (1994)
Publisher : Universitas Gadjah Mada

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Abstract

The objective of this study is to provide evidence on whether the subfomical organ is a neuroendocrine gland, by which the neurosecretion process to be carried out in this organ. This investigation involved the use of light microscopy by using an immunohistochemistry as well as histochemistry methods and transmission electron microscopy. Eighty adult male and female albino rats of the Lembaga Makanan Rakyat strain (Jakarta) weighing between 150-250 g, and 9 rats of Wistar strain, weighing between 200-300 g, were studied.According to morphology and by using immunohistochemistry and histochemistry methods, the results revealed that the subfomical organ was not a neuroendocrine gland that secreted a neurohormone or neurosecretory substances through a neurosecretion process.Key Words: subfomical organ-neurosecretion process - transmission electron microscopy - inununohistochemistry technics - histochemistry technics.
Prealbumin level at biochemical marker of nutritional assessment in premature infants Achmad Surjono, Achmad Surjono
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 21, No 04 (1989)
Publisher : Journal of the Medical Sciences (Berkala Ilmu Kedokteran)

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Abstract

Controversies in adequate nutrition for premature infants still exist. No single anthropometric or biochemical measures currently available are reliable for premature nutritional assessment.The aim of this study is to determine the usefulness of serial prealbumin serum levels in identifying adequacy of nutritional intake in premature infants during their neonatal period. A group of 18 infants ranging in birthweight between 1030-2050 g, nursed in the Dr. Sardjito Hospital until one month of age were included for study. Breast and formula milk were given in increasing amount and depending upon acceptance 120 Cal/kg of body weight/day should be achieved. Peripheral capillary blood samples were obtained for prealbumin examinations (by radial-immunodiffusion method) on the first day and at weekly interval afterwards. The infants were weighed daily and serum albumin was examined on 14 and 28 days of age.It turns out that the mean serum prealbumin in the first day of life was 7.9 ± L8 mg% and a significant increment levels on weekly measurements were obtained. It is shown that no correlation was found.between the prealbumin and albumin levels. Body weights correlated poorly with serial prealbumin values.It seems that prealbumin, with a short half-life of 1.9 days can be used as a sensitive nutritional assessment in premature infants. Modifying of adequate protein and caloric provision could be applied early to prevent malnutrition in the neonatal period of premature infants.Key Words: prealbumin - serum albumin - premature infants - nutritional assessment - caloric requirement
Glycosilation reaction models and the role of Madagascar periwinkle (Catharanthus roseus CU G. Don) S leaves infusion as protein damage inhibitor Rizky Taufan Firdaus, Rizky Taufan Firdaus
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 36, No 1 (2004)
Publisher : Universitas Gadjah Mada

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Abstract

Background : Glycosilation is a reaction between protein and glucose in high concentration. The basic of this reaction is the continuous increase of glucose concentration, followed by a hooking between glucose with the amin primary structure of the protein. Beside form the AGEs, glycosilation reaction forms free radicals as the side product. The free radical reaction with the protein forms a crosslinking of the protein and then change the structure of the protein.Objectives : This research was carried out to know glycosilation reaction model and the role of madagascar periwinkle ICatharanthus roseus ELI G. Don) s leaves infusion as protein damage inhibitor. Method : This research is an experimental and explorative research. This research was carried out in two steps, the making of infusion and the test for protein damage inhibition by using the infusion of madagascar periwinkle s leaves and glyclazide.Result : The activity of madagascar periwinkles leaves infusion to inhibit the protein damage is 21,29% while the activity of glyclazide is 96,77%.Conclusion : The infusion of madagascar periwinkle (Caiharanihus roseus EL.] G. Don)s leaves can inhibit the protein damage because of the glycosilation reaction but lower than the glyclazides.Key words : Madagascar periwinkle - glycosilation - free radical - protein damage
Organisasi Apparat Pendidikan Di Universitas T. Jacob, T. Jacob
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 7, No 04 (1975)
Publisher : Journal of the Medical Sciences (Berkala Ilmu Kedokteran)

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Abstract

key words: organisasi pendidikan di universitas
Urographic examination using non-ionic contrast media Arif Faisal, Arif Faisal
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 24, No 04 (1992)
Publisher : Universitas Gadjah Mada

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Abstract

Non-ionic (Iopamiro) and ionic (Urografin 76%) contrast media were used for intravenous urographic examination. Three patients (6%) showed symptoms of side effect in ionic group; two of them without allergy history, but only one patient had an experience of allergy to shrimp, penicillin and dust. The symptoms of reaction were chills, dizziness and febris.There was no reaction in non-ionic group patients. The density of contrast media was superior in using Iopamiro.Key Words : intravenous urography - Iopamiro - Urografin 76% - allergy - radiology
Vitamin B12 dan Anemia Megaloblastik Harjani, Harjani
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 13, No 03 (1981)
Publisher : Journal of the Medical Sciences (Berkala Ilmu Kedokteran)

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Abstract

Vitamin B12 is an essential factor for DNA synthesis, and it is also needed in the reaction for the production of lipoprotein in myelin sheaths of the nerve system.It is known that vitamin B12 deficiency causes.among others disturbances in the nucleus formation and leads to megaloblastic anemias, with or without disturbances of the peripheral nerve system. Disturbances in the nucleus formation affect cells of tissues which have a relatively rapid turnover such as hemopoiedc precursors in the bone marrow and the mucosal epithelium of the gastrointestinal tract.As the importance of the role of the vitamin in the formation and the development of cells and as the deficiency of the vitamin may initiate a vicious circle which aggravates more and more the deficiency and the defect of the gastrointestinal mucosa, it is very important to cut the circle with, for example, a high dose of parentera I vitamin B12 with sufficient quantity and quality of food.Key Words: gastric intrinsic factor - methylcobalamin - hydroxocobalamin megaloblastic - anemia - vitamin B12

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