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Journal of the Medical Sciences (Berkala Ilmu Kedokteran)
Core Subject : Science,
Journal of the Medical Sciences (JMedSci) or Berkala Ilmu Kedokteran (BIK) is an international, open-access, and double-blind peer-reviewed journal, published by Faculty of Medicine, Public Health and Nursing, Universitas Gadjah Mada Yogyakarta Indonesia. JMedSci aiming to communicate high-quality articles in the areas of biomedical science from basic to clinical sciences.The journal welcomes papers from original articles, case reports, reviews, and book reviews. All papers published in JMedSci are freely available as downloadable pdf files. The journal began its publication on March 1973 and published quarterly (January, April, July, and October). JMedSci is abstracted and indexed in DOAJ, Crossref, Google Scholar, Sinta, Indonesia One Search. JMedSci is accredited by Directorate of General Higher Education, the Ministry of Research, Technology, and Higher Education, Indonesia
Articles 2,170 Documents
Leptospirosis Triwibowo, Triwibowo
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 8, No 04 (1976)
Publisher : Journal of the Medical Sciences (Berkala Ilmu Kedokteran)

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Abstract

Leptospirosis adalah penyakit vector-borne dan water-borne yang mernpunyai prevalensi tinggi terutama di daerah pertanian dan perkebunan di mana para pekerja banyak berhubungan dengan air dan lumpur. Gejala klinis sangat bervariasi mulai dari yang asimtomatik sampai penderita dengan gejala-gejala yang berat.Dilaporkan 2 buah kasus leptospirosis dari Rumah. Sakit Umum Tegalyoso, Klaten, seorang dengan gejala-gejala ringan, seorang lagi meninggal dunia sebelum mendapat pengobatan yang adekuat. Dibicarakan pula perjalanan klinik dan cara pemeriksaannya.
Percobaan Fiksasi Lateks (Rheuma Quick TM Test) Untuk Menunjukkan Adanya Faktor Rheumatoid Dalam Serum Penderita-Penderita Rheumatoid Arthritis Harjono Soeharto, Harjono Soeharto
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 6, No 01 (1974)
Publisher : Journal of the Medical Sciences (Berkala Ilmu Kedokteran)

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Abstract

kata kunci : penyakit reumatik
Lipid profile in non-insulin dependent diabetes mellitus with microalbuminuria I Gde Raka Widiana, I Gde Raka Widiana
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 26, No 01 (1994)
Publisher : Journal of the Medical Sciences (Berkala Ilmu Kedokteran)

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Abstract

To detennine whether non-insulin dependent diabetes mellitus (NIDDM) patients with microalbuminuria have significant abnormality in lipid profile which could result in increasing the cardiovascular risk, a cross sectional study had been conducted by matching in-patient and out-patient of the Department of Medicine, Dr. Sardjito General Hospital, Yogyakarta between October 1990 to May 1992.NIDDM patients with urinary albumin excretion rates (UAER) of 30 to 300 mg per 24 hours (microalbuminuria, incipient nephropathy) were matched for age and sex with NIDDM patients with UAER below 30 mg per 24 hours (control group). Venous blood samples were taken to determine blood sugar, total cholesterol, high density lipoprotein (HDL) cholesterol, low density lipoprotein (LDL) cholesterol and triglyceride levels. Sex. age. duration of diabetes, relative body weight, retinopathy and neuropathy were also determined.Four groups of 34 NIDDM with microalbuminuria (17 males and 17 females) were found, and 34 controls (17 males and 17 females) were studied. There were no significant difference in age, duration of diabetes, relative body weight and neuropathy. However, retinopathy was significantly higher in diabetic patient with microalbuminuria. No significant difference was found in LDL-cholesterol (122,58 ± 59,09 mg/di vs. 113,55 ± 42,25 mg/di, p = 0,24) and triglyceride (173.91 ± 89.06 mg/dl vs. 164.69 ± 69.69 mg/di, p = 0.31), fasting blood sugar (202.55 ± 87.01 mg/dl vs. 23061 ± 111.93 mg/dl, p = 0.13) and 2 hours after meal (253.91 + 89.46 mg/di vs. 284.38 + 114.40 mg/di, p = 0.11) in both groups. However HDL-cholesterol levels (35.94 ± 13.65 mg/dl vs. 4.3 ± 12.32 mg/di, p = 0.01) was significantly lower and the ratio of total cholesteroVHDL-cholesterol (6.31 ± 3.08 vs. 4.1 ± 1.13, p = 0.00017) was significantly higher in NIDDM patients with microalbuminuria compared to the control group...Key Words: diabetes mellitus - lipid profile - cholesterol - HDL cholesterol - cardiovascular risk factors
Karakteristik Anthropometrik Penduduk Pulau Palue Josef Glinka, Josef Glinka
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 16, No 02 (1984)
Publisher : Journal of the Medical Sciences (Berkala Ilmu Kedokteran)

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Abstract

The island of Palue belongs to the Lesser Sunda Archipelago on 121° 43 East and 8° 20 South, some 15 km north of Central Flores. The anthropometrical material given here was collected in 1966/67 by the author, At that time the island was a biological isolate. The number of individuals is 526 men and 296 women.Key Words: Indonesia - Lesser Sunda Islands - Palue - anthropometry - biological isolate
Melanogenesis in freckles patients analysis in facultative color of Melayu ethnic with skin phototype IV & V Catharina Sagita, Catharina Sagita
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 36, No 3 (2004)
Publisher : Universitas Gadjah Mada

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Abstract

Background: Patients with lack of DNA repair capacity syndrome prone to have skin cancers and usually have freckles on their skin. Freckles is considered as a risk factor for skin cancer. Repair of sun induced DNA damage was proved to stimulate melanogenesis. The difference of melanogenesis capacity between freckles and non freckles peoples has never been studied.Objective: To determine the difference of melanogenesis capacity between freckles and non freckles patients by measuring the difference of facultative-constitutive skin color in Melayu peoples with skin ptohotype IV-V.Method: A case control study was performed to determine the difference of melanogenesis capacity between 31 freckles subjects and 32 non freckles subjects.Result: There was no significant difference (p> 0.05) in melanogenesis capacity between freckles and non freckles subjects.Conclusion: There is no difference of melanogenesis respon between freckles and non freckles patient.Key words: freckles, melanogenesis, skin color, IV-V phototype skin
Farmakologi Klinik Suatu Introduksi Samekto Wibowo, Samekto Wibowo
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 7, No 02 (1975)
Publisher : Journal of the Medical Sciences (Berkala Ilmu Kedokteran)

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Abstract

Perkembangan keadaan memerlukan bidang pengetahuan Baru yakni: farmakologi klinik. Hal yang perlu diperhatikan ialah fungsi, organisasi dan keperluan-keperluannya. Hanya saja, sebelum putusan ke arah pembinaan farmakologi klinik haruslah didapat persesuaian dalam hal kebutuhannya, baik bagi rumah sakit maupun bagi fakultas kedokteran.Fungsi harus dijelaskan dulu, fungsi akademik dalam fakultas kedokteran dan fungsi service dalam rumah sakit. Adanya laboratorium farmakologi klinik dan service klinik akan banyak menghemat tenaga dan alat yang akan diperlukan oleh sebuah rumah sakit. Daripada tiap departemen rumah sakit membuat laboratorium sendiri-sendiri, akan lebih baik ada laboratorium sentral farmakologi klinik. Dan harus diingat, bahwa nanti mencakup pula status administratif, perencanaan staf tehnicus dan professionil, ruang kantor dan laboratorium serta fasilitas rumah sakit termasuk out-patient dan tentu saja dana (Wardell, 1974).Melihat kondisi kebutuhan yang sama, nampaknya Indonesia sudah harus mulai berfikir ke arah itu. Jalan awal yang paling sederhana ialah memberikan pelajaran farmakologi klinik pada mahasiswa. Dari sini perkembangan lebih lanjut farmakologi klinik akan dibina.
Insulin receptor and insulin resistance in type -2 diabetes Ahmad H. Asdie, Ahmad H. Asdie
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 24, No 02 (1992)
Publisher : Universitas Gadjah Mada

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Abstract

Resistance to the glucoregulatory effects of insulin is well-documented in type -2, non-insulindependent diabetes. Two separate factors may contribute in the pathogenesis, namely the obesity-related and the non-obesity-related.Obesity-related insulin resistance is associated with hyperinsulinemia, reduced numbers of insulin receptors on target cells. The mechanism by which the insulin receptor number is decreaSed is not clearly understood. This phenomenon is called "down regulation". If the defect in glucose transport can not be overcome at any insulin concentration, insulin unresponsiveness is present. This is caused by unidentified abnormalities distal to the receptor, "postreceptor defect".In non-obesity-related, a-cell dysfunction, secretion of abnormal insulin, failure to convert proinsulin to insulin, or hormonal antagonist to insulin, is thought to be responsible for the resistance.Key Words: type -2 diabetes mellitus - insulin receptor - insulin resistance - insulin antagonist - obesity-related and non-obesity-related factors
Peranan Puskesmas dalam Menghadapi Keratitis Ulcerosa A. Soemarsono, A. Soemarsono
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 13, No 01 (1981)
Publisher : Journal of the Medical Sciences (Berkala Ilmu Kedokteran)

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Abstract

Keratitis ulcerosa is a common disease in Yogyakarta and surrounding: This disease will cause blindness without good and right management. Usually it is encountered in rural areas caused by mud or pin, some materials in the field, for example wood or leaf and other corpora aliena.When complication occurs, perforation happens, resulting in total blindness.The treatment is easy when administered immediately. Sometimes there are difficult cases of keratitis ulcerosa which are resistent to treatment and need referral to the eye hospital after simple treatment is found to be unsuccessful in one week. From data presented the simple treatment is successful enough.Key Words: keratitis ulcerosa - health center - blindness - hypopyon - Aureomonas hydrophila
Beberapa ukuran antropometri pada atlet sepakbola dan bulutangkis di Yogyakarta Neni Trilusiana Rahmawati, Neni Trilusiana Rahmawati
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 28, No 02 (1996)
Publisher : Universitas Gadjah Mada

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Abstract

A study on some anthropometry measurements of soccer and badminton athletes in Yogyakarta had been done. The objective of the study was to investigate the differences of anthropometry measurements for different types of sport on soccer and badminton athletes in Yogyakarta.The subjects of the study consisted of 20 soccer players and 20 badminton players, with the age of 17 - 25 years. The t-test was used to know the differences of anthropometry measurements between soccer and badminton players.The results indicated that the average height, body weight, sitting height, biiliocristal breadth, upper arm and thigh girth of soccer players were significantly greater than those of badminton players. The biacromial breadth, calf girth, arm and total leg length between the two sport groups were not significantly different. There were somatotype differences between soccer and badminton players, and the major difference in the distribution of the two samples was that the soccer players were less endomorphic and ectomorphic than the badminton players.Further studies may explain those results with more consideration on different types of exercise performed by more samples.Key words: sport anthropology - soccer & badminton athletes - anthropometry somatotype bodymeasurements
Genetic syndromes associated with ocular anomalies Hartono, Hartono
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 19, No 02 (1987)
Publisher : Universitas Gadjah Mada

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Abstract

A syndrome is defined as the concurrence or running together of constant patterns of abnormal signs or symptoms. Syndromes can be either genetic or non-genetic in origins. Genetic diseases consist of genic diseases, chromosomic diseases and embryopathies. Genetic syndromes also consist of genic disease syndromes, chromosomic disease syndromes and embryopathic syndromes. Syndromes of genic diseases are caused by pleiotropic mutation of the genes which give rise to multiple (pleiotropic) effects. Syndromes of chromosomic diseases are caused by chromosomal derangement either by the abnormalities of their structure or their number. There are many genetic syndromes associated with ocular anomalies. Geeraets has collected 436 ocular syndromes either genetic and non-genetic in origins, and 49 of 135 recognizable human malformations collected by Smith are also associated with ocular defects. Some important chromosomic syndromes such as tkisomy 21, Patau, Edward, and cri-du-chat syndromes are also associated with ocular anomalies. Key Words: genetic diseases - pleiotropic effects - ocular anomalies - chromosomic syndromes - embryopathies

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