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Journal of the Medical Sciences (Berkala Ilmu Kedokteran)
Core Subject : Science,
Journal of the Medical Sciences (JMedSci) or Berkala Ilmu Kedokteran (BIK) is an international, open-access, and double-blind peer-reviewed journal, published by Faculty of Medicine, Public Health and Nursing, Universitas Gadjah Mada Yogyakarta Indonesia. JMedSci aiming to communicate high-quality articles in the areas of biomedical science from basic to clinical sciences.The journal welcomes papers from original articles, case reports, reviews, and book reviews. All papers published in JMedSci are freely available as downloadable pdf files. The journal began its publication on March 1973 and published quarterly (January, April, July, and October). JMedSci is abstracted and indexed in DOAJ, Crossref, Google Scholar, Sinta, Indonesia One Search. JMedSci is accredited by Directorate of General Higher Education, the Ministry of Research, Technology, and Higher Education, Indonesia
Articles 2,170 Documents
Thymoma Laporan Kasus Dengan Tinjauan Pustaka Roekmini Soedibjo, Roekmini Soedibjo
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 17, No 02 (1985)
Publisher : Universitas Gadjah Mada

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Abstract

Three cases of thymoma were reported. Each was located in the anterior part of the media - stinum. The symptoms were dyspnea, cough, and increased blood pressure which possibly is caused by the pressure on the mediastinal organs by the tumor. In all cases either the macroscopic-or the microscopic examinations were benign. Histologically the tumor showed areas of epithelium cells and lymphocytes separated by connective tissues septum which were seen also in the gross picture. No invasive tumor was found in the surrounding tissues or organs. There was no myasthenia gravis found in all the three cases. Key Words: mediastinal pressures symptom - thymoma - tumor - thymus - lymphoma
Protective immure responses against fatal malarial infection in mice with blood stage malaria vaccin. Supargiyono, Supargiyono
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 26, No 03 (1994)
Publisher : Journal of the Medical Sciences (Berkala Ilmu Kedokteran)

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Abstract

Studies were carried out to establish suitable infection and immunization method to facilitate investigation on the protective host immune responses against acute malarial infection. Combinations of experimental model using two species of rodent malaria parasites Plasmodium vinckei vinckei and Plasmodium vinckei petteri, two immunization methods were tested, to determine which model are suitable for studying any aspect of host immune responses during protective malarial immunization.The results indicated that the infection of P. v. vinckei and P. v. petteri in LACA or in BALB/c mice generally produce acute and lethal infections. Infection of P.v.vinckei in these experimental models seems more severe than P. v. petteri, and neither intravenous nor intraperitoneal immunization gave significant protection against homologous infection. However, immunization using 108 blood stage parasite P. v. petteri could protect LACA mice from the lethality of homologous challenge, and it seems that cell mediated mechanisms play an important role in host responses against infection. Therefore, P. v. petteri infection in LACA mice and immunization using 10 blood stage parasites given intravenously or intraperitoneally represent a suitable model to study some aspects of host immune response mechanism during malarial immunization.Key Words : Plasmodium vinckei vinckei - Plasmodium vinckei petteri - immune response - cellular immunity - homologous parasites
Bom Atom di Atas Hiroshima) Suatu Pengalaman Nyata Arifin Bey, Arifin Bey
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 21, No 03 (1989)
Publisher : Journal of the Medical Sciences (Berkala Ilmu Kedokteran)

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Abstract

The author was one of the students from occupied territories in South East Asia studying in Hiroshima when the city was atomic bombed in 1945. Tokyo was carpet-bombed in 1944-45 and foreign students were spread to other relatively safe cities. Before August 1945 Hiroshima was never bombed, but air raid alarms sounded every morning. On August 6 after the alarm was cleared the author saw a "lightning" flashed through a classroom window, and the school building, 2 km from the hypocenter, suddenly crashed, After being unconscious for a while, he noticed that the sunny morning has turned into darkness.Outside, people were running in fear and aimlessly. Some showed bleeding and others had their clothes torn or burnt. The skin of quite a few people was torn off and hanging loosely like gloves. Everything in sight was flattened to the earth and some carts were on fire. The river was full with rafts and evacuating people. Many immersed themselves in the water to alleviate the extreme heat and repetitively asked for water to drink. Most people had no clothes any more and their skin ap• Reared red.Numerous people were walking among the dying and dead bodies looking for their relatives and friends. Identification was difficult due to the damaged face and decaying bodies. It took days to dispose the dead bodies by trucks. Ten days after the bombing, the students were brought to Tokyo, and here blood tests disclosed that some suffered from leucopenia. A Malayan student died in Kyoto during the trip to Tokyo.Key Words: atomic bomb-- Hiroshima -- medical effects of nuclear war -- thermal radiation -- shock wave
Epidemiology of cervical-root caries on teeth: High prevalence in the coca leaf chewing in the Andean people. Etty Indriati, Etty Indriati
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 36, No 1 (2004)
Publisher : Journal of the Medical Sciences (Berkala Ilmu Kedokteran)

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Abstract

Background: Cervical-root caries on teeth often called rampant caries or circular caries often suffered by children who consumed bottled sweet milk. In adult, cervical-root caries occurs in unique cases such as cancer patients who undertake chemotherapy, and narcotic addicts.Objective: The research was aimed to study the dental and oral health of Andean people who have traditionally been chewing coca-leaves as a part of their cultural and integral lives.Materials and Method: The subject of study was 210 Aymara people from highland Chile and Bolivia, Andes. They were given questionnaire whether they chew coca leaves or not. Without knowing whether one chewed coca leaves or not, each individual was examined for: the carious teeth, the caries location, the periodontal stage, the oral pH, the molar radices, the molar loss, and the total number of teeth preserved.Result: The result showed that people who chewed coca-leaves every day suffered cervical-root caries on their molar teeth, only radices of molars preserved, or even lost their molar teeth. They also suffered tongue desquamation and periodontal damage at the buccal area of molar teeth. In contrast, those who did not chew coca-leaves were relatively free from these dental disadvantages. Statistical analysis showed significantly high correlation between duration and intensity of chewing coca leaves with dental disadvantages (R=0,62 for molar loss; R=0,63 for bad periodontal status; and R =0,54 for cervical-root caries).Conclusion: It is concluded that habitual chewing of coca leaves damaged the periodontal region of the molar area, caused the root of the molar teeth to expose and led to cervical-root caries, then, only roots of molar preserved, and last, the lost of molar teeth. The high prevalence of cervical-root caries in coca-leaves chewers is in accord with other conditions such as cancer patients who undertake chemotherapy, and narcotic addicts. The alkaloid in the coca leaves are associated with the drying out the mouth leading to less self-cleansing and damaging the cervical-root area. Understanding the cultural tradition in a society is important if we were to understand the disease processes.Key words: coca leaves - Andes - epidemiology - cervical-root caries - molar
Applikasi System ABO, MN dan RH Dalam Sengketa Kebapaan T. Jacob, T. Jacob
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 8, No 01 (1976)
Publisher : Journal of the Medical Sciences (Berkala Ilmu Kedokteran)

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Abstract

kata kunci : golongan darah ABO - sengketa kebapaan
Pengobatan Bronchopneumoni pada Anak Dengan Kemicetine succinate S. Soegijarsi, S. Soegijarsi
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 5, No 02 (1973)
Publisher : Universitas Gadjah Mada

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Abstract

Keywords: bronchopneumoni, Staphylococcus, micro organisme
The involvement of mesolimbic dopaminergic system in ovulation in rat (Rattus norvegicus) Soedjono Aswin, Soedjono Aswin
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 25, No 01 (1993)
Publisher : Universitas Gadjah Mada

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Abstract

Mesolimbic dopaminergic system involvement in the ovulatory process was studied in the immature superovulation rats (Rartus norvegicus). Nucleus ventralis tegmenti (NVT, area A-10) was neurochemically lesioned by stereotaxically placed injection of I Vg 6-hydroxydopamine (6-OHDA) into the brain. Ovarian weight, frequency and rate of ovulation, the number of corpora lutea found in the ovaries, and histologic features of the ovaries were observed.The results of the present experimental study indicate that neurochemical lesion of NVT with 6-OHDA produced a significant (p<0.01) decrease in the ovarian weight, as well as the ovulation rate and the number of corpora lutea found in the ovaries, compared to the shank-operated control and normal control groups. The frequency of ovulation, however, was not affected; it means that all groups of immature rats underwent ovulation. It is interesting to note that the ovulation rate of the lesioned group was suppressed (but not prevented) by about 60% as shown by the decrease in the number of corpora lutea found in the ovaries and in the number of ova per ovulation. Histologic features of the ovaries of the lesioned group performed an inhibition of follicular development as evidenced by the characteristic :features of the induction of polycystic degeneration, beside the decrease in the number of corpora lutea found in the ovaries.It is concluded that mesolimbic dopaminergic system specifically plays a significant role in the regulation of ovulatory process in the immature superovulation rats. Based on the present data it is hypothesized, that lesioning mesolimbic dopaminergic system chemically with 6-OHDA resulted in significant decrease in luteinizing hormone releasing hormone (LHRH) released from hypothalamus, which in turn ensued the decrease in the tonic release of luteinizing hormone (LH), which is known responsible for the development of the ovarian follicles; but it seems that there is a slight suppression in the pulsatile release of LH, which is responsible for the initiation of ovulation.Key Words: nucleus ventralis tegmenti - mesolimbic dopaminergic systenm - 6-hydronydopanine -    ovulation - Rattus riorvegicus
Gangguan Kosmetik Karena Kelainan Pigmentasi Kulit Hardyanto, Hardyanto
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 13, No 04 (1981)
Publisher : Journal of the Medical Sciences (Berkala Ilmu Kedokteran)

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Abstract

Patients with pigmentary changes on their skin seek advise primarily for cosmetic reasons, although these are usually asymptomatic and without systemic consequencei. The most common types of pigmentary disturbances are freckles, melasma, lentikines, melanoderma, vitiligo and leukoderma.This article discusses normal melanogenesis, and clinical features, pathogenesis and treatment of pigmentary abnormalities of the skin,Patients suffering from pigmentary abnormalities attending the clinic of the Department of Dermatology and Venereology, Gadjah Mada University Hospital, are presented, From 1978 to 1979, 450 patients were noted. 26% males and 74% females, with the following breakdown: 18.2% melasma, 20.2% freckles, 12.4% melanoderma, 6.4% lentigo, 84.7% vitiligo and 8.1% leultoderma . -Key Words: pigmentary abnormalities - hyperpigmentation and hypopigmentation - epidermal melanin unit - hydrocluinon - psoralen
Application of non-specific esterase enzyme microassays to detect potential insecticide resistance of Aedes aegypti adults in Yogyakarta, Indonesia Sugeng Juwono Mardihusodo, Sugeng Juwono Mardihusodo
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 28, No 04 (1996)
Publisher : Journal of the Medical Sciences (Berkala Ilmu Kedokteran)

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Abstract

By bioassay Aedes aegypti larvae collected from Yogyakarta were found to be susceptible to temephos and malathion and by using microplate enzymatic assay Ae. aegypti larvae collected from the same sites were potentially resistant to the organophosphate insecticides due to elevated esterase activity in hydrolyzing a-naphthyl acetate substrate used in the enzymatic reaction from the same sites might be potentially resistant to OP insecticides due to the same mechanism. The homogenates of the mosquito adult stages from the fields were microassayed using a-naphthyl acetate substrate compared to that colonized in the laboratory. From a series of studies the results were concluded that Ae. aegypti adults in Yogyakarta were susceptible and potentially resistant to insecticides due to elevated a-naphthyl acetate esterase activity.Key words: Aedes aegypti - organophosphate insecticides - insecticide resistance - non-spesific esterase -biochemical test.
Hubungan Sistem Lymphe Dan Vena Pada Bagian Superficial Jantung Djaka Prakosa, Djaka Prakosa
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 6, No 02 (1974)
Publisher : Journal of the Medical Sciences (Berkala Ilmu Kedokteran)

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Abstract

18 cow hearts have been studied to demonstrate the existence of communications between lymph vessels and veins on the superficial surface of the heart. The findings showed that in 9 cases such communications could be demonstrated, being 1 or 2 in number on each heart. Most of them were located on the sternocostal surface, especially near the apex.The diameters of the lymph vessels near the communications were found to be 80 to 480 microns.These anastomosis were assumed to play a role in certain conditions such as in lymphatic or venous stasis.

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