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e-Journal Pustaka Kesehatan
Published by Universitas Jember
ISSN : 2355178X     EISSN : 27213218     DOI : -
Core Subject : Health, Science,
Health Professions Library & Information Science
e-Journal “Pustaka Kesehatan” merupakan jurnal elektronik ilmiah berISSN (ISSN: 2355-178X) yang menerbitkan artikel hasil penelitian di bidang kesehatan secara umum meliputi: Kedokteran, Kedokteran Gigi, Kesehatan Masyarakat, Farmasi, dan Ilmu Keperawatan. Artikel yang dikirim belum pernah dipublikasikan atau tidak dalam proses penerbitan dalam jurnal ilmiah lain. e-Journal “Pustaka Kesehatan” diterbitkan tiga kali dalam setahun, yaitu bulan Januari, Mei, dan September.
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Articles 30 Documents
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Search results for , issue "Vol 2 No 1 (2014)" : 30 Documents clear
Pengaruh Student Team Achievement Division (STAD) terhadap Pengetahuan dan Sikap Mencegah Merokok Siswa Madrasah Aliyah Pondok Pesantren Nurul Qarnain Sukowono Jember (The Effect of Student Team Achievement Division (STAD) towards Knowledge and Attitude i Feri Ekaprasetia; Dodi Wijaya; Erti Ikhtiarini Dewi
Pustaka Kesehatan Vol 2 No 1 (2014)
Publisher : UPT Percetakan dan Penerbitan Universitas Jember

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Abstract

Teenagers’ knowledge and attitude in preventing smoking becomes the factor of teenager to smoke. One of the ways to improve teenagers’ knowledge and attitude is doing education about health which is delivered using Student Team Achievement Division (STAD) method. Kind of experiment used is quasy experimental with non equivalent control group plan.Sampling method using multistage random sampling with the total respondent is 48 which consist of 24 control group and 24 intervention group. The result of analyzing data using Wilcoxon test is P value knowledge = 0,013 and P value attitude = 0,005 whereas the comparison between control group and intervention group using Mann Whitney test is P value knowledge and attitude is 0,000 and observing the degree of guiltiness (α = 0,05) so P value < 0,05. The analysis result is knowledge variable 22 respondents (91,7%) have high knowledge, 2 respondents (8,3%) average knowledge and none of the respondents which have low knowledge after being done intervention. In attitude variable, 12 respondents (50%) have good attitude, 12 respondents (50%) have average attitude and none of the respondents which have bad attitude after being done intervention. The conclusion is there are meaningful effects of STAD to the knowledge and attitude of preventing smoking to the teenagers of MA Nurul Qarnain and knowledge and attitude have diferented betwen experiment group and control group. Keywords : STAD, knowledge, attitude, smoking, teenagers
Perbedaan Kualitas Hidup Lansia yang Tinggal di Komunitas dengan di Pelayanan Sosial Lanjut Usia (The Different of Quality of Life Among the Elderly who Living at Community and Social Services) Amalia Yuliati; Ni'mal Baroya; Mury Ririanty
Pustaka Kesehatan Vol 2 No 1 (2014)
Publisher : UPT Percetakan dan Penerbitan Universitas Jember

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Abstract

Quality of life is a very board concept that was affected by individual physical condition, psychological, level of independence, and individual's relationship with the environment. This research aimed to determine differences in the quality of life of the elderly who living at community and Social Services, according to the physical, psychological, social, and environmental domain. This research was analytically studies using cross sectional design. The number of sample was 210 respondent. Mann Whitney and Kruskal Wallis test (alpha 0,05) was applied to analyze the data. There were not significant difference between quality of life of the elderly living at community and at Social Services in Jember (p=1.000). Based on domain quality of life, the were significant difference between physical, psychological, social, and environmental domain of the elderly living at community and Social Services in Jember.   Keywords: elderly people, quality of life, community, Social Services  
Daya Antibakteri Ekstrak Kulit Apel Manalagi (Malus sylvestris Mill.) Terhadap Pertumbuhan Streptococcus mutans (Antibacterial Activity of Manalagi Apple Peel (Malus sylvestris Mill.) Extract on The Growth of Streptococcus mutans) Jannata Hafidata Rabbani; Gunadi Achmad; Ermawati Tantin
Pustaka Kesehatan Vol 2 No 1 (2014)
Publisher : UPT Percetakan dan Penerbitan Universitas Jember

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Abstract

Apple is a popular fruit which is consumed by many people in Indonesia. Manalagi apple's peel contains polyphenols that have antibacterial effects. Streptococcus mutans is the normal flora that can cause oral disease. One of alternative medications to prevent the disease by using natural products as antibacterial. This research is aimed to determine the antibacterial activity manalagi apple's peel extract on the growth of S. mutans and minimum concentration to inhibit growth. The method of this research is well diffusion method with 8 samples for each treatment. Samples consisted of five treatment groups which is manalagi apple's peel extract with concentration of 100%, 50%, 25%, positive control group (chlorhexidine 0.2%), and negative control group (aquadest sterile). Data were analyzed using the Kruskal-Wallis and Mann-Whitney test. The results of this research showed that manalagi apple's peel extract at all concentrations have antibacterial activity against the growth of S.mutans. Minimum inhibition concentration of manalagi apple's peel extract is 25%. The conclusion of this research proves that manalagi apple's peel extract has antibacterial activity against S.mutans growth.   Keywords: Antibacterial activity, manalagi apple's peels, Streptococcus mutans, well difussion method.
Pengaruh Komposisi Hidroksi Propil Metil Selulosa K-15 dan Etil Selulosa N-22 terhadap Prosentase Kelembapan Air dan Pelepasan Meloksikam dari Sediaan Plester (The Influence of Hidroxy Propyl Methyl Cellulose K-15 and Ethyl Cellulose N-22 Ratio on Procent Monica Iwud Rully Pramesthie; Lidya Ameliana; Budipratiwi Wisudyaningsih
Pustaka Kesehatan Vol 2 No 1 (2014)
Publisher : UPT Percetakan dan Penerbitan Universitas Jember

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Abstract

The present research has been undertaken with the aim to develop a transdermal patch of meloxicam with ratio of hydroxy propyl methyl cellulose (HPMC) K-15 and ethylcellulose (EC)N-22 as a matrix were 1:9 (Formula 1), 2:8 (Formula 2), 3:7 (Formula 3).The physicochemical parameters like organoleptic and % moisture content were evaluated. Released test using dissolution apparatus were carried out in 500 mL of phosphate buffer saline pH 7.4 ± 0.05 at temperature 37 ± 0.5°C with speed of swirl 50 rpm. Results were analyzed by statistic programmed of SPSS using one way analysis of variance with degree of believed 95% (α = 0,05).The results of evaluation of patch dosage, transdermal patches were found yellow, odorless and dry. Result of moisture content F(1) 1.168 ± 0.009 %; F(2) 1.841 ± 0.019 % and F(3) 2.584 ± 0.025 %. Result of in vitro drug release F(1) 364.865 ± 0.701 µg/cm2.menit1/2; F(2) 397.212 ± 0.441 µg/cm2.menit1/2 and F(3) 439.277 ± 0.559 µg/cm2.menit1/2. It can be concluded that the combination ofHPMC K-15 and EC N-22 at ratio 7:3 was the best choice for manufacturing transdermal patch based on physicochemical and the release profile.   Keywords: transdermal patch, meloxicam, hydroxypropylmethyl celulosa, ethylcellulosa
Uji Aktivitas Anti Hiperurisemia Ekstrak n-Heksana, Etil Asetat, dan Etanol 70% Biji Jinten Hitam (Nigella sativa) terhadap Mencit Hiperurisemia (Anti Hyperuricemic activity of n-Hexane, Ethyl acetate, and Ethanol 70% of Black Cumin Seed (Nigella sativa) Umar Dian Prambudi Kusuma; Siti Muslichah; Evi Umayah Ulfa
Pustaka Kesehatan Vol 2 No 1 (2014)
Publisher : UPT Percetakan dan Penerbitan Universitas Jember

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Abstract

The aim of this study was to determine the in vivo anti-hyperuricemic effect of black cumin extract. Black cumin was extracted with n-hexane, ethyl acetate, and ethanol 70% continously. Fifteen mice were divided into five groups K-, K+, P1, P2, and P3. Group K- as negative control (chicken liver juice 0,2 % b/v) and group K+ as positive control (allopurinol 10 mg/kg b.w.). Group P1, P2, and P3 received n-hexane, ethyl acetate, and ethanol 70% black cumin extract. The extracts were given to mice in 200 mg/kg b.w dose for 4 days. The blood samples were taken an hour after potassium oxonate injection (300 mg/kg b.w) to inhibit uricase enzym. The data was collected and analyzed using one way ANOVA and LSD test. The result showed that activity of ethyl acetate extract of black cumin has no significant difference of possitive control. Based on phytochemistry screening it has terpenoid, saponin, and alkaoid. Terpenoid has anti-hyperuricemic effect but its mechanism still unknown.   Keywords: hyperuricemic, Nigella sativa, terpenoid.
Faktor yang Berhubungan dengan Pemanfaatan Pelayanan Antenatal oleh Ibu Hamil di Wilayah Kerja Puskesmas Tempurejo Kabupaten Jember Tahun 2013 (Correlated Factors of Antenatal Services Utilization by Pregnant Women at Community Health Center of Tempurejo, Ulul Lailatul Mardiyah; Yennike Tri Herawati; Eri Witcahyo
Pustaka Kesehatan Vol 2 No 1 (2014)
Publisher : UPT Percetakan dan Penerbitan Universitas Jember

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Abstract

Antenatal care is a governmental program as part of efforts to reduce maternal mortality. Indicators of success for prenatal care is K4 scope. Tempurejo Health Center has the lowest coverage of K4 in Jember in 2012 with its percentage is 61.38%, less than the target (94%). The purpose of this study was to analyze correlated factors of antenatal services utilization by pregnant women at Community Health Center of Tempurejo which includes knowledge, attitudes, beliefs, availability of health care, service of 10T, affordability, worker’s service, and family support. This study is a cross sectional analytic design. Samples are 87 pregnant women who stay in the working area Tempurejo Health Center with the age of pregnancy of the 2nd and 3rd trimester. Collecting data using questionnaires and analyzed using correlation Somers'D with Confidence Interval 95%. The results showed correlation between knowledge, attitudes, service of 10T, affordability, worker’s service and family support officer with antenatal services utilization. However, there was no correlation between beliefs and availability of health care with antenatal services utilization. Keywords: pregnant women, antenatal care, utilization
Efek Ekstrak Teh Hijau (Camellia sinensis) terhadap Memori Kerja Spasial Tikus Wistar (Rattus novergicus) Remaja yang Diinduksi Etanol Prasetia Aji Ramadhan; Muhamad Ihwan Narwanto; K Dian Sofiana
Pustaka Kesehatan Vol 2 No 1 (2014)
Publisher : UPT Percetakan dan Penerbitan Universitas Jember

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Abstract

Ethanol is a well-known agent causing organ damage including hippocampus. Hippocampus damage will reduce spatial memory. This study aimed to determine the effects of green tea extract on spatial memory function in adolescent rats following ethanol administration. One of cathecin derivates in green tea is EGCG which is believed to prevent hippocampal damage due to ethanol. The research was conducted on 25 rats, divided into 5 groups with 2 control groups and 3 experimental groups. A control group 1 (K1) was given 20 % ethanol with a dose of 2g/kgBW, while a control group 2 (K2) was only given with distilled water. All experimental groups (P1,P2 and P3) were given ethanol 2gr/kgBW and green tea extract with a dose of 108mg/200gBW, 216mg/200gBW, and 432mg/200gBW, respectively for P1, P2, and P3. Administration of ethanol and green tea extracts were performed for 14 days. The rats' spatial memory were tested by observation using the Radial Arm Maze ( RAM ) for 10 days. The number of the right arm in K1 was fewer than K2, P1, P2 and P3, but in K2 the right arm similar with P2 and higher than P1 and P2. In conclusion, the green tea extract influence the spatial memory of ethanol-induced adolescent rat. Keywords: Ethanol, green tea extract, Radial Arm Maze, spatial memory
Hubungan Tingkat Kognitif Perawat tentang Caring dengan Aplikasi Praktek Caring di Ruang Rawat Inap RSU dr. H. Koesnadi Bondowoso (The Correlation between Nurses Cognitive Level on Caring with Caring Practice Application in the Inpatient Unit RSU dr. H. K Bagus Setyo Prabowo; Anisah Ardiana; Dodi Wijaya
Pustaka Kesehatan Vol 2 No 1 (2014)
Publisher : UPT Percetakan dan Penerbitan Universitas Jember

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Caring is one form of behavior exhibited by a nurse in performing nursing care services. Purpose of this study was to analyze correlation between nurses cognitive level on caring with caring practice application in the inpatient unit RSU dr. H. Koesnadi Bondowoso. Population in this study were 71 nurses RSU dr. H. Koesnadi Bondowoso with 41 nurses as sample. Nurse characteristics data analysis used univariate analysis, whereas for nurses cognitive levels and nurses caring practices application used the chi-square test with α significance level of 5%. Descriptive data analysis of nurses caring cognitive level showed that 26 nurses (56.5%) had good cognitive and 20 nurses (43.5%) had less cognitive. Applications caring practices showed 23 nurses (50.0%) behaved caring and 23 nurses (50.0%) behaved less caring. Results showed that p value = 0.037 with α significance level of 0.05, and thus Ho was rejected, which means there  was a correlation between nurses cognitive level on caring with caring practice application in the inpatient RSU. dr. H. Koesnadi Bondowoso. Odds ratio 4.4 which means the nurse who had good cognitive level on caring would 4,4 times behaved caring compared with nurses who had sufficient cognitive level of caring.   Keywords: cognitive level nurse, caring, caring practice application
Studi Aktivitas Antioksidan Senyawa 1-(p-klorobenzoiloksimetil)-5-fluorourasil dengan Metode Molecular Docking dan Metode DPPH (Antioxidant Activity of 1-(p-chlorobenzoyloxymethyl)-5-Fluorouracyl Using Molecular Docking and DPPH Method) Brahmansyah Diar Rosiarto; Ayik Rosita Puspaningtyas; Diana Holidah
Pustaka Kesehatan Vol 2 No 1 (2014)
Publisher : UPT Percetakan dan Penerbitan Universitas Jember

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Cellular damage caused by reactive oxygen species (ROS) free radical and antioxidant activity has an important role as free radical scavenging in body. This study was carried out to evaluate in vitro antioxidant and ligand afinity toward human ROS receptor (PDB code: 3ZBF). In DPPH method, 1-(p-chlorobenzoyloxymethyl)-5-fluorouracil dissolved in etil acetat, while 5-fluorouracil and ascorbic acid as standard dissolved in methanol. The free radical scavenging activity was measured spectrometrically with maximum wavelength at 512 nm. DPPH method show that ascorbic acid have strong antioxidant activity (IC50 = 19.092 ppm), while 1-(p-chlorobenzoyloxymethyl)-5-fluorouracil (IC50 = -2,500,245 ppm) and 5-fluorouracil (IC50 = -4,998 ppm) have not antioxidant activity. Molecular docking (in silico) toward human ROS receptor was indicate 1-(p-chlorobenzoyloxymethyl)-5-fluorouracil (Ki = -6.2 ± 0.04 kkal/mol) has best activity than ascorbic acid (Ki = -4.8 ± 0.19 kkal/mol) and 5-fluorouracil (Ki = -4.6 ± kkal/mol).   Keywords: 1-(p-chlorobenzoyloksimethyl)-5-fluorouracil, 5-Fluorouracyl, antioxidants, DPPH, molecular docking
(Kadar LDL dan HDL Dalam Darah Model Tikus Periodontitis (Blood Level of LDL and HDL in Periodontitis Rat Model ) Nugraha Agung Marda; Suci Wulan Agustin; Susilawati Ayu Dewa
Pustaka Kesehatan Vol 2 No 1 (2014)
Publisher : UPT Percetakan dan Penerbitan Universitas Jember

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Backgroud. Increased levels of low density lipoprotein (LDL) and decreased levels of high density lipoprotein (HDL) in the blood is a risk factor for atherosclerosis leading to Coronary Heart Disease (CHD). Risk factor of atherosclerosis are multifactorial such as consuming high lipid diet, excessive eating, sedentary, and inflammatory response. According to the recent study indicated that inflammatory response could affect LDL and HDL blood levels that related to the risk of atherosclerosis lesion formation. Therefore, we suspected that periodontitis could affect LDL and HDL. Purpose. The purpose of this study was to show the effect of periodontitis in LDL and HDL. Methods. This experimental study used the post test only control group design. The object were 8 male wistar rats (Rattus norvegicus) with inclusion criterias were male rats, ±200 gr body weight, 3-4 months age, having a healthy condition, good appetite, and normal behavior. The rats were devided into two groups, i. e. control group and treatment group (periodontitis group) with 4 rats in each group. Periodontitis rat model was created by fitting cervical left low molar tooth with wire ligature and injected with 0,02 ml P. gingivalis ATCC 33277 (dosage 5µg/0,05 ml) in bucal sulcus, three times a week for 4 weeks (28 days), all of the rats were fed with standard diet. On day 29th all groups of rats were sacrificed and intracardial blood were taken 3 cc for examination of LDL and HDL blood levels by electrospectrophotometric method. Data were analyzed by T-test. Result. Result showed that periodontitis rat model had a significantly higher LDL levels compared to control group (P <0,05) and HDL levels were lower than controls, but the difference was not significant (P >0,05). Conclusion and suggestion. Based on this study periodontitis increase LDL blood levels. Further research related with duration of periodontitis are needed because periodontitis is usually a chronic disease and have a long lasting effect . In addition, the role of the severity of periodontitis are required to learn.   Keywords: HDL, LDL, Periodontitis.

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