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e-Journal Pustaka Kesehatan
Published by Universitas Jember
ISSN : 2355178X     EISSN : 27213218     DOI : -
Core Subject : Health, Science,
e-Journal “Pustaka Kesehatan” merupakan jurnal elektronik ilmiah berISSN (ISSN: 2355-178X) yang menerbitkan artikel hasil penelitian di bidang kesehatan secara umum meliputi: Kedokteran, Kedokteran Gigi, Kesehatan Masyarakat, Farmasi, dan Ilmu Keperawatan. Artikel yang dikirim belum pernah dipublikasikan atau tidak dalam proses penerbitan dalam jurnal ilmiah lain. e-Journal “Pustaka Kesehatan” diterbitkan tiga kali dalam setahun, yaitu bulan Januari, Mei, dan September.
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Articles 30 Documents
Search results for , issue "Vol 2 No 1 (2014)" : 30 Documents clear
Potensi Ekstrak Kulit Buah Manggis (Garcinia mangostana L.) Buatan Pabrik Terhadap Peningkatan Aktivitas Mikrobisidal Sel Neutrofil yang Dipapar Streptococcus mutans (The Potency of Manufactured Mangosteen Peel Extract (Garcinia mangostana L.) Towards In Hamidah Azzahra; Peni Pujiastuti; Purwanto Purwanto
Pustaka Kesehatan Vol 2 No 1 (2014)
Publisher : UPT Percetakan dan Penerbitan Universitas Jember

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Abstract

Abstrac Neutrophils are the first non-specific immune cells that successfully overcome the presence of antigens, starting with attachment and then terminate the antigen by phagocyte process. Mangosteen peel extract (Garcinia mangostana L.) possesses a compound that contains pharmacological activity. The purposes of this study were to determine the benefits of manufactured mangosteen peel extract toward increased neutrophil microbicidal activity and the most effective concentration in increasing neutrophil microbicidal activity exposed to S. mutans. Microbicidal activity of neutrophil cells was tested by firstly taking blood isolate neutrophils from peripheral veins of healthy people, secondly incubated with mangosteen peel extract, thirdly exposed to S. mutans, fourthly subcultured on a BHI-A medium, then incubated for 24 hours, and finally calculated the number of colonies by using colony counter. Results of the data were analyzed by using Kolmogorov-Smirnov, Levene, Kruskal-Wallis and Mann-Whitney. The results showed each treatment group had significant difference with value of 0,001 (p<0,05). The treatment group incubated with the mangosteen peel extract had less number of colonies compared to the group which was not given mangosteen peel extract. In conclusion, the mangosteen peel extract could increase neutrophils microbicidal activity that was exposed to S. mutans.. Keywords: mangosteen (Garcinia mangostana L.), microbicidal, neutrophil                                    
Validasi dan Penetapan Kadar Rhodamin B pada Lipstik yang Beredar di Sekitar Universitas Jember dengan Metode KLT-Densitometri (Validation TLC-densitometry method for determination of Rhodamine B in Lipstick at Jember University Area) Risa Wahyu Ananda; Nia Kristiningrum; Yuni Retnaningtyas
Pustaka Kesehatan Vol 2 No 1 (2014)
Publisher : UPT Percetakan dan Penerbitan Universitas Jember

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Rhodamine B is one of the synthetic dyes that forbidden in cosmetics. The study was conducted to validate TLC-densitometry method for determination Rhodamin B in lipstick at Jember University area. Samples was taken by purposive sampling method. The analyte were dissolved with ethanol 70% and cromatographed on silica Gel GF 254 TLC plate using etil asetat : metanol : amoniak in the ratio (15:3:3) (v/v/v). Then, validation and determination sample can be done using TLC-densitometry with maximum wavelength 554 nm. Method was found linear over the concentration range of 6 – 32 ng with correlation coefficient of 0,9965. Spesificity showed calculation of purity and identity more than 0.99. The limits of detection and quantitation limits obtained 0.558 and 1.86 ng/spot. The precision test which includes precision repeatability and intermediate precision, amounting to RSD 6.57% and test accuracy , resulting % recovery and RSD value of 97.74 % ± 2.54% . Based on these results lipstick sample purposively sampled none containing rhodamine B and safe consumer use. Keywords: TLC - densitometry , lipstick , rhodamine B , the validation method of analysis
Respon Limfosit T Sitotoksik Pada Gingivitis Setelah Pemberian Kurkumin (Citotoxic T Lymphocytes Response in Gingivitis After Curcumin Given) Nitawati Meilisa Ni Putu; Dwi Merry Christmarini Robin; Mei Syafriadi
Pustaka Kesehatan Vol 2 No 1 (2014)
Publisher : UPT Percetakan dan Penerbitan Universitas Jember

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Gingivitis is a form of periodontal disease most common in the community. Gingivitis is caused by bacteria in subgingival plaque, one of them is Porphyromonas gingivalis. Curcumin is a phenolic yellow pigment obtained from the powdered rhizome of Curcuma sp. which has anti-inflammatory effects. Curcumin can reduce the number and responses of cytotoxic T lymphocyte by signing on IL-1, IL-2, IL-12, and TNF. Variables observed in this study is the number and response of cytotoxic T lymphocyte in male Wistar rats gingiva. 16 male Wistar rats were divided into two groups: control and treatment groups. To cause gingivitis rats were injected with bacteria P. gingivalis 3x108 CFU concentrations as much as 0.02 ml of the gingival sulcus maxillary left for 2 days. The control group was given PBS and treatment group was given curcumin dose of 0.03 mg / g BW in intragastric starting from day 2 after induction of P. gingivalis. Rats sacrificed on day 3 (72 hours after the induction of P. gingivalis) and day 5, followed by extraction, fixation, tissue processing to be preparations with HE staining and IHC. Observation of the results carried out using a light microscope. Results showed that there was no cytotoxic T lymphocytes in the control and treatment groups, but in HE staining found existence of lymphocytes guess is that memory T lymphocytes (CD45). The conclusion of this study is in IHC staining method there is no difference in the number of cytotoxic T lymphocytes in the control group and the treatment, but in HE staining found existence of lymphocytes guess is that memory T lymphocytes, and the clinical features are redness and swelling until day 3 which the gingival more redness in the control group compared to the treatment group and healing has occurred on day 4 to day 5 in the control and treatment groups. Keywords: Citotoxic T lymphocytes, Curcumin, Gingivitis, Immunohistochemica
Perspektif Pasien dengan Perlindungan Sosial Kesehatan tentang Peran Advokasi Perawat di Ruang Rawat Inap Kelas III Rumah Sakit Paru Jember (Nurse's Advocation Role in Patients With Social Health Insurance in Class III Inpatient Wards Paru Hospital Jember Suyanti Suyanti; Nurfika Asmaningrum; Anisah Ardiana
Pustaka Kesehatan Vol 2 No 1 (2014)
Publisher : UPT Percetakan dan Penerbitan Universitas Jember

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Various reports about service quality to social health insurance (Jamkesmas) participants pointed out that the given service to social health insurance was not compatible with the program’s purpose. As health professionals whom always keep patients company, nurses are required to be able to give primary care to all patients. Advocacy is one of nurse’s roles, in carrying out this role, nurses are helping patients making decision instead of making the decision for patients. This study is a qualitative study with phenomenological approach. Samples are acquired by purposive sampling method with the result 4 samples out of population. Data was obtained by interview using an interview guide as well as field notes. This data was analyzed with Colaizzi method. Results of study give rise to ten research themes which conclude a description of the particular goals. Those themes are the role of nurses in the inpatient admission procedure, provide information about the procedures of action, provide a suitable environment to the condition of the patient, assisting other health professionals, accompany the patient to undergo a medical examination, the type of actions taken, the role of nurses as patient managers, the nurse's role in planning after discharge, and JAMKESMAS service system. The nurses as care giver in Paru Hospital Jember should consider to the advocation role in all their actions. Keywords : patients’ perception, nurse advocation role
Dampak Program Bina Keluarga Balita (BKB) Terhadap Tumbuh Kembang Anak Balita 6-24 Bulan (The Impact Of Bina Keluarga Balita (BKB) Program To The Growth Development Of Toddler 6-24 Months) Andri Wahyuni; Sulistiyani Sulistiyani; Leersia Yusi Ratnawati
Pustaka Kesehatan Vol 2 No 1 (2014)
Publisher : UPT Percetakan dan Penerbitan Universitas Jember

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The growth development is two difference phenomenons, but it is related and difficult to separated, that is growth and development. Bina Keluarga Balita (BKB) Program is one of the Keluarga Berencana (KB) program which purpose is to increase the knowledge and skills of parents and other family members to build the growth development of toddler by their ages. The aim of this study is to analyze the impact of Bina Keluarga Balita (BKB) program to the growth development toddler 6-24 months in the working area of Sumbersari subdistrict of Jember. The research type was observational analytic with cohort approaches. The samples about 130 toddlers (65 toddlers who family is participate and not participate on BKB) taken by Proportional Random Sampling. Based on Chi-Square results of statistical tests, it’s known that the difference of parenting nutrition, love pattern, teach pattern, and growth development between toddler 6-24 months who family is participate and not participate on BKB with the Sig or p = 0.0001 (p<α).   Keywords: Bina Keluarga Balita Program, Growth Development Of Toddler, 6-24 Months
Terapi Nutritif Modifikasi Modisco Menggunakan Ekstrak Nanas Meningkatkan Hemoglobin pada Tikus Wistar KEP Berat Alfi Kamalia; Erma Sulistyaningsih; Sugiyanta Sugiyanta
Pustaka Kesehatan Vol 2 No 1 (2014)
Publisher : UPT Percetakan dan Penerbitan Universitas Jember

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The data from the Health Research Association of Indonesian Ministry of Health in 2010 showed approximately 35.6% infants having PEM. The diet therapy for severe PEM is modisco. However, due to protein deficiency such as a protease enzyme resulting in nutrients malabsorption, modisco has not been able to compensate the lack of protein in PEM. It requires an active substance to increase protein absorption by adding a proteolytic enzyme. One of the source of proteolytic enzyme is pineapple. The study aimed to prove that addition of pineapple extract on modisco can increase levels of albumin and hemoglobin in severe PEM rats. This was a true experimental study with pre-post test control group design. The sample were 25 male Wistar rats aged 2 months. The data analysis using the Pairwise T test, one way ANOVA followed by LSD showed a significantly difference between pre and post test for both albumin and haemoglobin. The pineapple extract at a dose of 9 and 11 mg/day increased albumin level. And the dose of 7, 9 and 11 mg/day pineapple extract increase haemoglobin level. In conclusion, a modisco modification using pineapple extract for nutritive therapy increased both albumin and hemoglobin levels on severe MEP rats.   Keywords: Severe PEM, Modisco, Pineapple extract
Kualitas Hidup Wanita Menopause (Quality of Life Among Menopausal Women) Dessy Irwienna Putri; Dwi Martiana Wati; Yunus Ariyanto
Pustaka Kesehatan Vol 2 No 1 (2014)
Publisher : UPT Percetakan dan Penerbitan Universitas Jember

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AbstractMenopause is a condition when woman’s menstrual period ends because ovaries stopproducing estrogen and progesteron. The deficiency of these hormones cause women havemenopausal symptoms that can decrease their quality of life. This study aimed to analyzethe quality of life among menopausal women. This was a cross sectional study. The sampleconsisted of 128 menopausal women and their age ranged 45-59 years old. Chi-square,Anova, and Independent Sample t Test were used to analyze the data. The result showedbetter quality of life was experienced by women who had high education, did exerciseregularly, didn’t have chronic disease, and had mild menopausal symptoms. According toquality of life domain, physical domain was better in women who had married, did exerciseregularly and had mild menopausal symptoms. Psychological domain was better in womenwho had high education, did exercise regularly and didn’t have chronic disease.Environmental domain was better in women who had high education, did exercise regularly,and had mild menopausal symptoms. Whereas, social domain was better in married women.Based on this study, menopausal women are adviced to do exercise regularly so their qualityof life can be improved.Keywords: menopausal women, quality of life
Uji Aktivitas Antiplatelet Ekstrak Etanol Kubis Merah (Brassica oleracea var. capitata L.) Antiplatelets activity of red cabbage ethanolic extract (Brassica oleracea var. capitata L.) Rizki Rica Rachim Fadilah Putri; Evi Umayah Ulfa; Rini Riyanti
Pustaka Kesehatan Vol 2 No 1 (2014)
Publisher : UPT Percetakan dan Penerbitan Universitas Jember

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Antiplatelet aggregation effect of red cabbage ethanolic extract (Brassica oleracea var. capitata L.) was measured by bleeding time on Balb-C mice. The test substances given orally during the period of 8 days. Bleeding time was measured on first day and 9th day. Red cabbage ethanolic extract were divided into 3 doses: wich are 9.69 mg/kg body weight; 19,38 mg/kg body weight, and 38,76 mg/kg body weight. After getting the percentage of bleeding time increase, data were analyzed by analysis of variance test (Anova), followed by individual comparison within the groups by LSD test. The test substances above respectively increased bleeding time 58 ± 16%; 70,7 ± 8,9 %, and 113 ± 12%. As the conclusion, red cabbage ethanolic extract doses 38,76 mg/kg body weight could increase bleeding time as well as positive controle 129 ± 8,2%. Keywords: antiplatelets, Brassica oleracea red cabbage, bleeding time.
Pengaruh Ekstrak Daun Pepaya Terhadap Jumlah Sel Limfosit Pada Gingiva Tikus Wistar Jantan Yang Mengalami Periodontitis (The effect of papaya leaves extract to the number of lymphocytes cells to the male-wistar rat's gingiva that undergo periodontitis) Utama Bramanto Satrya Dimas; Yuliana Mahdiyah Da’at Arina; Muhammad Nurul Amin
Pustaka Kesehatan Vol 2 No 1 (2014)
Publisher : UPT Percetakan dan Penerbitan Universitas Jember

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Background. Porphyromonas gingivalis (P. gingivalis) is plaque bacteria caused periodontitis with proteolitic characterised that makes some damages to the periodontal tissues. Lymphocytes are chronic inflamed cells which have specific characteristic when periodontitis was occured. Papaya is known as herbal plants, which contains substances which have antimicroba and antiinflamation activities in its leaves. The purpose of this research is to determinate the effect of papaya leaves extract to the number of limfocyte cells to the male-wistar rats gingival that was periodontitis. Twenty male-wistar rats that were divided to the five groups with different treatments. The first group is control of other group, the second group is treatment group that was induced with P. gingivalis and assembled with a ligature, while the remaining of groups were added with the extract of papaya leaves sondation by certain concentration 25% for the third group, 50% for the fourth group, and 75% for the last group after getting some treatments as the second group. The result of the research showed that the highest lymphocytes cells was found to group that was induced by P. gingivalis and assembled with a ligature. In the contrary, the lowest lymphocytes cells was found to the fifth group that was treated with the extract of papaya leaves 75%. It concluded that papaya leaves extract decreased the number of lymphocytes in periodontitis male-wistar rats gingival. The most effectively of papaya leaves extract that was used is 75%. Advanced research about the compound of the extract of papaya leaves which most influential and the mechanism to the decrease of the number of lymphocytes cells are needed. Keywords: Papaya Leaves Extract, Periodontitis, P. gingivalis
Efek Antiangiogenik Ekstrak Etanol Buah Mahkota Dewa (Phaleria macrocarpa (Scheff.) Boerl.) pada Membran Korio Alantois (CAM) Embrio Ayam Roat Yeti Mustafida; Al Munawir; Rosita Dewi
Pustaka Kesehatan Vol 2 No 1 (2014)
Publisher : UPT Percetakan dan Penerbitan Universitas Jember

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Angiogenesis is the growth of new blood vessels that are used to supply nutrients and oxygen including cancer cells. Phaleria macrocarpa contains tannin, saponin, alkaloid, and flavonoid, known as an antiangiogenesis. This study determined the antiangiogenic effects of ethanolic extract of Phaleria macrocarpa on chorio allantoic membrane of chicken embryos. The antiangiogenesis trials used chorio allantoic membrane of 9 days chicken embryos. There were 5 groups, negative control group [K(-)] and 4 treatment groups (P), each group containing 4 eggs. K(-) group using aquadest and tween 80%; P groups with ethanolic extract of Phaleria macrocarpa at a concentration 10 ug/µL, 40 ug/µL, 80 ug/µL, 160 ug/µL for P1, P2, P3, dan P4 respectively. The number of new blood vessels on chorio allantoic membrane were K(-): (42.5 ± 14.57), P1: (28.25 ± 3.59), P2: (28.5 ± 1.73), P3: (15 ± 4.32), and P4: (6.5 ± 1.73). In conclusion, the ethanolic extract of phaleria macrocarpa has an antiangiogenic effect on chorio allantoic membran by decreasing the number of new blood vessels.Keywords: angiogenesis, Phaleria macrocarpa, ethanolic extract, chorio allantoic membrane

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