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Media Farmasi : Jurnal Ilmu Farmasi (Journal Of Pharmaceutical Science)
Published by Universitas Ahmad Dahlan
ISSN : 14127946     EISSN : 25035223     DOI : 10.12928
Core Subject : Health, Science,
Chemistry Immunology & microbiology Materials Science & Nanotechnology Medicine & Pharmacology
Media Farmasi is a scientific journal published by the University of Ahmad Dahlan worked closely with Ikatan Apoteker Indonesia (IAI). Media Farmasi published two times a year, namely in March and September since 2002 with ISSN 1412-7946 and e-ISSN 2503-5223. The article published in the Journal Media Farmasi selected by editors and reviewed by the reviewer. Articles published in Media Farmasi must not be published in other journals or have been previously published. Media Farmasi publishes a review article, original article, as well as short communication in all scopes of Pharmaceutical Science.
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Articles 5 Documents
 1 
Search results for , issue "Vol. 20 No. 1: March 2023" : 5 Documents clear
The relationship level of community's knowledge and attitude toward the use of antibiotics in Gandaria, South Jakarta Teodhora, Teodhora; Maliawati, Eka Putri
Media Farmasi: Jurnal Ilmu Farmasi Vol. 20 No. 1: March 2023
Publisher : Universitas Ahmad Dahlan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.12928/mf.v20i1.21117

Abstract

Antibiotics will be beneficial and have the anticipated therapeutic effect if prescribed and administered as instructed. The purpose of this study was to evaluate community attitudes and knowledge levels regarding the use of antibiotics, as well as the relationship between these two variables. The sample size for this descriptive-analytic study was 95 respondents, and a cross-sectional design was used. The sampling technique utilized was purposeful sampling. Women made up the bulk of responses (65.3%), and their age range was 36 to 45 (44.2%). The latest educational levels indicated were high school (61.1%), antibiotic use in the past or present (100%), and housewife (38.1%). The respondent received scores of 62.1% for "excellent" knowledge, 3.5% for "adequate" learning, and 7.4% for "poor" expertise. In contrast, there were 0.0% of participants in a horrible disposition, 52.6% with an acceptable attitude, and 47.4% with an excellent attitude. The Chi-Square test findings showed a significant value of 0.097, or more significant than 0.05, between the variable amount of knowledge and attitudes against antibiotics. The p-value (> 0.05) indicates no correlation between the level of competence and perspectives regarding the use of antibiotics. Education, knowledge, and attitudes toward antibiotics were found to be correlated, with a p-value of (0.05). It was determined that the local population had a good and insightful understanding of antibiotics.   
Antibacterial activity of Sappan (Caesalpinia sappan L.) wood methanol extract against Staphylococcus epidermidis Atunnisa, Waro; Zamzani, Irfan; Nashihah, Siti
Media Farmasi: Jurnal Ilmu Farmasi Vol. 20 No. 1: March 2023
Publisher : Universitas Ahmad Dahlan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.12928/mf.v20i1.21900

Abstract

The entry and proliferation of microorganisms, such as bacteria, cause skin infections. One of the bacteria that causes skin infections is Staphylococcus epidermidis. Sappan (Caesalpinia sappan L.) wood has been known to have various pharmacology activities, one of which is antibacterial, so its activities need to be developed and improved. This study aimed to determine the activity of the methanol extract of Sappan (C. sappan L.) wood as an antibacterial against S. epidermidis. This research was conducted by extracting Sappan wood powder with 96% methanol as solvent using the Ultrasound-Assisted Extraction (UAE) method and testing for antibacterial activity with concentrations of 25%, 50%, 75% and 100% using the disc method. Results showed that the methanol extract of Sappan wood had an antibacterial activity; the highest inhibition zone at a concentration of 75% was 29.25 mm. Sappan wood was expected to be a promising alternative therapy for overcoming acne problems and can increase economic value for the wider community. 
The level of community knowledge about the use of antibiotics Sugihantoro, Hajar; Munawaroh, Ismea; Inayatillah, Fidia Rizkiah; Indrawijaya, Yen Yen Ari
Media Farmasi: Jurnal Ilmu Farmasi Vol. 20 No. 1: March 2023
Publisher : Universitas Ahmad Dahlan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.12928/mf.v20i1.23917

Abstract

Knowledge and use of antibiotics play a large and important role in the success of treatment, so that they do not cause negative effects, such as the cause of antibiotic resistance. The purpose of this study was to determine the profile and level of knowledge of the community regarding the use of antibiotics in Banyior Village, Sepulu District, Bangkalan Regency, East Java, Indonesia. This research is a cross-sectional descriptive study. The measurement is a closed questionnaire. Data were analyzed using SPSS version 18. The survey was conducted from October 2021 to December 2022 on 325 residents of Banyior Village. The result is that the antibiotic most often used by respondents is amoxicillin with a percentage of 47%. The majority of respondents, 45 percent, get antibiotics from drugstores or stalls. The knowledge level of the general public shows a good level of knowledge of 6.82%, an average level of knowledge of 19.60% and a low level of knowledge of 73.57%. The most widely used antibiotic by respondents in this study was amoxicillin, where the most common way to obtain it was through drug stores/stalls and public knowledge of the use of antibiotics was still low.
Mapping rheumatoid arthritis susceptibility through integrative bioinformatics and genomics Medi Sushanti, Nining; Adikusuma, Wirawan; Afief, Arief Rahman; La’ah, Anita Silas; Firdayani, Firdayani; Chong, Rockie; Zakaria, Zainul Amiruddin; Purwanto, Barkah Djaka; Satria, Rahmat Dani; Khair, Riat; Septama, Abdi Wira; Irham, Lalu Muhammad
Media Farmasi: Jurnal Ilmu Farmasi Vol. 20 No. 1: March 2023
Publisher : Universitas Ahmad Dahlan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.12928/mf.v20i1.24912

Abstract

Rheumatoid arthritis (RA) is an autoimmune disease that influences several organs and tissues, especially the synovial joints, and is associated with multiple genetic and environmental factors. Numerous databases provide information on the relationship between a specific gene and the disease pathogenesis. However, it is important to further prioritize biological risk genes for downstream development and validation.  This study aims to map RA-association genetic variation using genome-wide association study (GWAS) databases and prioritize influential genes in RA pathogenesis based on functional annotations. These functional annotations include missense/nonsense mutations, cis-expression quantitative trait locus (cis-eQTL), overlap knockout mouse phenotype (KMP), protein-protein interaction (PPI), molecular pathway analysis (MPA), and primary immunodeficiency (PID). 119 genetic variants mapped had a potential high risk for RA based on functional scoring. The top eight risk genes of RA are TYK2 and IFNGR2, followed by TNFRSF1A, IL12RB1 and CD40, C5, NCF2, and IL6R. These candidate genes are potential biomarkers for RA that can aid drug discovery and disease diagnosis.
Relationship between knowledge and behavior levels of antibiotic usage among pharmacy patients in sub-districts puguh and tegorejo Kendal Sonia, Monica Lita Amay; Al Farizi, Gilang Rizki; Ovikariani, Ovikariani
Media Farmasi: Jurnal Ilmu Farmasi Vol. 20 No. 1: March 2023
Publisher : Universitas Ahmad Dahlan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.12928/mf.v20i1.25497

Abstract

Antibiotic resistance is a very serious condition for public health care around the world. This situation is due to improper use of antibiotics that can be affected by self-medication or improper consumption of antibiotics due to lack of knowledge and lack of public awareness of antibiotic use. This study is aimed to determine the relationship of the level of knowledge of the behavior of the use of antibiotics in Pharmacy patients in sub-districts of Puguh and Tegorejo Kendal. This study was an observational study with a cross sectional approach in the research period of May-June 2022. The data collection was carried out by purposive sampling with a total of 130 respondents. The instruments used in the study are structured. Spearman test results showed that there is a relationship with the level of knowledge of antibiotic use behavior (p = <0.05) ; r = 0.549. The conclusion of the study is that there is a relationship between the level of knowledge of antibiotic use behavior in pharmacy patients in sub-districts of Puguh and Tegorejo Kendal.  

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