Althea Medical Journal
Althea Medical Journal (AMJ) is a peer reviewed electronic scientific publication journal which is published every 3 months (March, June, September, and December). Althea Medical Journal publishes articles related to research in biomedical sciences, clinical medicine, family-community medicine, and public health.
Articles
1,078 Documents
<![CDATA[Overview of Dental Caries Severity and Nutritional Status in Preschool Children in Jatinangor in September 2014 ]]>
<![CDATA[Putri, Anggita Dwi]]>;
<![CDATA[MA, Etty Sofia]]>;
<![CDATA[Djais, Julistio T.B.]]>
<![CDATA[ Althea Medical Journal Vol 3, No 2 (2016) ]]>
Publisher : <![CDATA[Althea Medical Journal ]]>
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<![CDATA[Background: The prevalence of dental caries in Indonesia is still high. The pain caused by dental caries could interfere with childrenâs ability to eat and even their growth. This study aimed to discover the proportion of dental caries severity related to nutritional status in children aged 3â5 years.Methods: This descriptive study was carried out in 3 Pre-school Education Centers (Pendidikan Anak Usia Dini, PAUD) in the sub-district of Jatinangor in September 2014. Sixty four children were selected through cluster random sampling as samples. The degree of caries was measured by def-t index. Nutritional status was determined by anthropometric measurements, i.e. body weight (BW)/body height (BH) or body mass index (BMI)/Age index.Results: There were 59 (92%) children suffered from dental caries out of which 48 (75%) children was severe, 6 (9%) children was moderate, and 10 (16%) children was mild. Furthermore, 18 (28%) children were mildly undernourished and 46 (72%) were well-nourished. Out of all the children with severe dental caries, 16 (34%) children had mild undernourishment while out of all the children with moderate-mild dental caries, 2 (12%) children had mild undernourishment.Conclusions: Children aged 3-5 years in the sub-district of Jatinangor have a relatively severe dental caries even though their nutritional status are generally good. Mildly undernourished children largely come from the group with severe dental caries. [AMJ.2016;3(2):314â8]Â DOI:Â 10.15850/amj.v3n2.464]]>
<![CDATA[Etiology of Allergic Contact Dermatitis based on Patch Test ]]>
<![CDATA[Anggraini, Dita Maulida]]>;
<![CDATA[Sutedja, Endang]]>;
<![CDATA[Achadiyani, Achadiyani]]>
<![CDATA[ Althea Medical Journal Vol 4, No 4 (2017) ]]>
Publisher : <![CDATA[Althea Medical Journal ]]>
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DOI: 10.15850/amj.v49n4.1265
<![CDATA[Background: Allergic contact dermatitis is a type of contact dermatitis, whose prevalence tends to increase every year. Patch test is an important diagnostic test to confirm the disease. The result of patch test can help doctors to perform appropriate treatment. The aim of the study was to identify the most frequent allergen causing allergic contact dermatitis based on patch test results.Methods: This was a descriptive retrospective study among patients who underwent patch test at the Dermatology and Venereology Clinic in Dr.Hasan Sadikin General Hospital Bandung, Indonesia from August 1st, 2014 to August 31st, 2015. The patch test result was obtained from the patientâs medical record and recapitulation data. The patientâs medical record would be collected based on inclusion and exclusion criteria. This study also collected demographic data of the patients, including age, sex, and occupation.The collected data were presented using tables.Results: Out of 45 patientâs medical records, 19 patients were male (42.2%) and 26 patients were female (57.8%). Nickel sulphate was the most frequent allergen with 17 sensitization. Thirteen out of 17 patients who were sensitized by nickel sulphate were females. A great majority of the patients were in the age group of 15â44 years. Most of the patients were students (42.2%). Allergic contact dermatitis (64.4%) was the main clinical diagnosis among the patients.Conclusions: The most frequent allergen causes allergic contact dermatitis is nickel sulphate.]]>
<![CDATA[Comparison of Age of Thelarche between Obese and Normal Girls ]]>
<![CDATA[Yunitasari, Yunitasari]]>;
<![CDATA[Fadil, R.M. Ryadi]]>;
<![CDATA[Dwiyatnaningrum, Fenny]]>
<![CDATA[ Althea Medical Journal Vol 3, No 3 (2016) ]]>
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<![CDATA[Background: Childhood obesity has become a major concern in recent years. The increasing childhood obesity prevalence may occur as the result of food consumption with high content of calories, fat, cholesterol and the lack of physical activity. Obesity in children will also affect their pubertal development. Puberty is a period in which maturation of the reproductive function is achieved.In girls, the initial sign of puberty is thelarche, defined as the appearance of breast bud underneath the areola.The onset of puberty depends on many factors, one of them is nutritional status especially obesity. This study was conducted to compare the age of thelarche between obese and normal girls.Methods: An analytical study using cross sectional method was conducted. This study was held in Bandung, West Java, Indonesia, during the period of SeptemberïOctober 2013. Data were obtained from 3 elementary schools, selected by multistage random sampling.The total subject was 46. Data were analyzed using the Mann-Whitney and chi-square test.Results: Thelarche occurred at age 9 years 4 months in the obese group compared to 11 years 2 months in the normal group. The analysis using Mann-Whitney test showed the difference was statistically significant (p<0.001). Based on age group, 42% obese girls attained thelarche between ages 8ï9 years, while 63% girls in the normal group attained thelarche between ages 11ï12 years. The analysis using chi- square test showed that the difference was statistically significant (p<0.001).Conclusions: Thelarche occurs earlier in obese girls compared to normal girls. [AMJ.2016;3(3):411â5]DOI: 10.15850/amj.v3n3.906]]>
<![CDATA[Correlation between Sperm Motility and Morphology in the Success Rate of in Vitro Fertilization Procedure ]]>
<![CDATA[Ramadhan, Praditya Virza]]>;
<![CDATA[Rezano, Andri]]>;
<![CDATA[Permadi, Wiryawan]]>
<![CDATA[ Althea Medical Journal Vol 3, No 4 (2016) ]]>
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<![CDATA[Background: In vitro fertilization (IVF) is one of the assisted reproductive technology that has been used in treating infertility. Unfortunately, not every IVF procedure achieves 100% success in fertilizing the oocyte. It has been studied that the percentage of normal motile sperm and percentage of normal sperm morphology play a key role in this process. This study was conducted to evaluate correlation between sperm motility and morphology in the success rate of IVF. Methods: This study was an observational analytic involving medical records of infertile couples who were treated by IVF procedure in Dr.Hasan Sadikin General Hospital Bandung in 2009â2014. The variables that were used in this study were percentage of sperm motility, percentage of sperm morphology and fertilization rate.The collected data was analyzed using nonparametric Mann Whitney test and Spearman correlation test.Result: This study showed that there was a significant difference between the fertilization rate group and sperm motility (p=0,048) but there was no significant correlation between motility and the entire fertilization rate (p=0,319). This study also indicated that there was no significant difference between fertilization rate group and sperm morphology (p=0,232) and there was no significant correlation between sperm morphology and fertilization rate (p=0,720).Conclusions: Motility might has a role in determining the success rate of in vitro fertilization; meanwhile morphology does not have any role in determining the success rate of in vitro fertilization. [AMJ.2016;3(4):520â5]Â DOI:Â 10.15850/amj.v3n4.957]]>
<![CDATA[Vitamin C Intakeand Risk Factors for Knee Osteoarthritis ]]>
<![CDATA[Destiani, Nadia Ayu]]>;
<![CDATA[Fatimah, Siti Nur]]>;
<![CDATA[Dewi, Sumartini]]>
<![CDATA[ Althea Medical Journal Vol 4, No 2 (2017) ]]>
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DOI: 10.15850/amj.v4n2.1067
<![CDATA[Background: Knee osteoarthritis (OA) is a degenerative disease of the knee joints characterized by progressive softening and disintegration of articular cartilage. In OA, which is influenced by several risk factors, free radicals are increased by local ischemia in the cartilage. As an exogenous antioxidant, vitamin C also plays an important role in collagen and glycosaminoglycan synthesis. This study was carried out to identify vitamin C intake as well as risk factors in knee OA. Methods: The study population was determined by non-probability sampling with convenient approach to knee OA patients at the Rheumatology Outpatient Clinic of Dr. Hasan Sadikin General Hospital in OctoberâNovember 2013. Data were obtained through questionnaire interview about risk factors, severity index of OA and vitamin C intake profile. Data presentation was conducted by descriptive method.Results: There were 47 patients diagnosed with knee OA in the Rheumatology Outpatient Clinic. The result showed that 7 patients (14.9%) had low vitamin C intake for the last 3 months. There were 30 patients with family history of OA (63.8%). Thirty two patients (68.1%) were passive smokers, 44 patients (93.6%) had history of repeated use of knee joints and majority of respondents had obesity. Conclusions: Most of the subjects have sufficient vitamin C intake and more than half have risk factors that may contribute to the incidence of knee OA. DOI: 10.15850/amj.v4n2.1067 ]]>
<![CDATA[Antibacterial Effect of Pulsatilla chinensis towards Staphylococcus aureus, Shigella dysenteriae, and Salmonella typhi ]]>
<![CDATA[Fong, Sim Chee]]>;
<![CDATA[Mulyana, Yanti]]>;
<![CDATA[Girawan, Dolvy]]>
<![CDATA[ Althea Medical Journal Vol 3, No 2 (2016) ]]>
Publisher : <![CDATA[Althea Medical Journal ]]>
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<![CDATA[Background: Pulsatilla (P.) chinensis is a kind of traditional Chinese medicine (TCM) that has antibacterial effect. It is used to treat diarrhea, dysentery, and other diseases. The P. chinensis is composed of some potent antibacterial substances including protoanemonin, saponin, oleanolic acid. The study aimed to determine the antibacterial effect of P. chinensis towards staphlococcus aureus, Shigella dysenteriae, and Salmonella typhi.Methods: This was an experimental descriptive study that was conducted in 2014 using two methods, diffusion and dilution method. In diffusion method, 5 holes were made on the agar that bacteria were growing and different concentrations of P. chinensis infusion were placed in different hole. The inhibitory effect was measured by the inhibition zone. In dilution method, 8 test tubes with decreasing concentration of P. chinensis infusion were mixed with the bacteria suspension and Mueller Hinton Solution. The minimal inhibitory concentration (MIC) was measured by the last clear test tube. The test tube with solution that showed absence of bacteria on culture indicated the minimal bactericidal concentration (MBC).Results: In diffusion method, P. chinensis infusion showed inhibitory effect towards S. aureus and bacteriostatic effect towards S. dysenteriae and S. typhi. In dilution method, there was no antibacterial activity detected.Conclusions: P. chinensis infusion has inhibitory effect on S. aureus and bacteriostatic effect on S. dysenteriae and S. typhi. [AMJ.2016;3(2):292â5]DOI:Â 10.15850/amj.v3n2.467]]>
<![CDATA[Effect of Short Term Cardiac Rehabilitation Program on Quality of Life in Patients with Coronary Artery Disease ]]>
<![CDATA[Marita, Ina]]>;
<![CDATA[Sastradimaja, Sunaryo B.]]>;
<![CDATA[Tiksnadi, Badai Bhatara]]>
<![CDATA[ Althea Medical Journal Vol 4, No 3 (2017) ]]>
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<![CDATA[Background: Cardiac rehabilitation (CR) programs are known to be one of the effective managements which aim to improve the quality of life (QoL) in coronary artery disease (CAD). However, there is still controversy about the effect on QoL dimension. The purpose of this study is to determine the effect of short term cardiac rehabilitation program on quality of life in patients with coronary artery disease.Methods: The study design used was a quasi experimental study with repeated measurements in consecutive sampling involving 11 subjects with CAD from SeptemberâNovember 2015 in Cardiorespiratory Clinic and Gymnasium of Physical Medicine and Rehabilitation and Cardiac Unit Services, Dr. Hasan Sadikin General Hospital Bandung. The cardiac rehabilitation program was performed for 4 weeks. The quality of life was scored using medical outcomes study short form 36 (SF-36) questionnaire before and after CR program. Statistics obtained in this study were analyzed using paired t-test and Wilcoxon test.Results: This study involved 11 male patients with CAD with an average age of 58 (11) years old with the diagnosis of CAD post CABG (n=6), CAD post PCI (n=4), and CAD unrevascularized (n=1). The average total score of quality of life questionnaire SF-36 demonstrated a significant increase (p<0.001) after CR program 87.27(8.5) as compared to before CR program 49.09(8.4). This improvement occurred in all QoL dimensions.Conclusions: Short term cardiac rehabilitation program can improve the quality of life in patients with coronary artery disease. ]]>
<![CDATA[Score of Fine Motor Skill in Children with Down Syndrome using Nintendo Wii ]]>
<![CDATA[Sinaga, Puspasari]]>;
<![CDATA[Prananta, Marietta Shanti]]>;
<![CDATA[Fadlyana, Eddy]]>
<![CDATA[ Althea Medical Journal Vol 3, No 3 (2016) ]]>
Publisher : <![CDATA[Althea Medical Journal ]]>
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<![CDATA[Background: Down syndrome occurs due to an extra chromosome 21, known as Trisomy 21. In addition to delayed cognitive and speech development, children with Down syndrome may also experience delayed gross and fine motor development. Virtual Reality Therapy, such as Nintendo Wii is a computer-based technology that allows users to interact with a virtual three-dimensional scenario and the most innovative physical rehabilitation method. High scores indicate that the player has a good motor skill. This study aimed to examine the difference between the score of fine motor skill in children with and without Down syndrome.Methods: An analytic cross-sectional study was conducted from August to November 2015 to 40 children aged between 9â12 years old who came from public primary schools and special needs schools in Bandung, West Java. They were divided into 2 groups using random gender and age pairing; one group was children with Down syndrome and another other group was normal children. The childrenâ scores of Nintendo Wii game were collected three times. The collected data were statistically analyzed by Chi-Square test.Results: The proportion of children with low-grade fine motor skill in Down syndrome group was larger than those with high-grade fine motor skill. In the other hand, in normal children group, the proportion was reversed compared to Down syndrome group. There was a significant difference in score of fine motor skill between children with Down syndrome and normal children (p=0.000).Conclusions: The fine motor skill of children with Down syndrome is poorer than normal childrenâs. [AMJ.2016;3(3):371â5]Â DOI: 10.15850/amj.v3n3.882Â ]]>
<![CDATA[Characteristics of Anterior Segment Dysgnesis in Pediatric and Strabismus Ophthalmology Unit at Cicendo Eye Hospital 2012-2014 ]]>
<![CDATA[Ramadanti, Sarah Nurul]]>;
<![CDATA[Irfani, Irawati]]>;
<![CDATA[Khairani, Astrid Feinisa]]>
<![CDATA[ Althea Medical Journal Vol 3, No 4 (2016) ]]>
Publisher : <![CDATA[Althea Medical Journal ]]>
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<![CDATA[Background: Developmental anomalies in congenital anomalies cause malformation, such as Anterior Segment Dysgenesis (ASD). Disorder in maturation of anterior segment of the eye occurs in ASD, associated with increased risk of glaucoma. This relation is not supported with enough data about characteristics pediatric patients with ASD in Indonesia. The aim of the study was to describe characteristics ASD in pediatric patient Cicendo Eye Hospital based on patientsâ identity, clinical profile and obstetrics profile.Methods: This study used a descriptive method and conducted retrospectively. Data were collected from medical records of patient with ASD in Pediatric Ophthalmology and Strabismus Unit at Cicendo Eye Hospital, from January 2012 to December 2014. This study was conducted from July to November 2015. Total sampling based on inclusion criteria were used in this study. Statistic software was used to analyze data. Results: This study used a descriptive method and conducted retrospectively. Data were collected from medical records of patient with ASD in Pediatric Ophthalmology and Strabismus Unit at Cicendo Eye Hospital, from January 2012 to December 2014. This study was conducted from July to November 2015. Total sampling based on inclusion criteria were used in this study. Statistic software was used to analyze data. Conclusions: Characteristics pediatric patients with ASD at Cicendo Eye Hospital based on patients identity are mostly patients diagnosed in infant age group, from outside Bandung, and mostly boys. Based on clinical profile most diagnosis is congenital glaucoma, bilateral dominantly, and without complication. Based on obstetric profile most patients with ASD were born at term without difficulties. [AMJ.2016;3(4):616â70]Â DOI:Â 10.15850/amj.v3n4.948]]>
<![CDATA[Validity of Immunoglobulin M Anti Salmonella typhi Serologic Test in Childhood Typhoid Fever ]]>
<![CDATA[Marsela, Hilda]]>;
<![CDATA[Setiabudi, Djatnika]]>;
<![CDATA[Indrati, Agnes Rengga]]>
<![CDATA[ Althea Medical Journal Vol 4, No 1 (2017) ]]>
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<![CDATA[Background: Typhoid fever, which mostly affects children, remains a major health problem in developing countries. Early diagnosis will help the management and thus, reduce morbidity and mortality. However, a rapid diagnostic test that detects the presence of immunoglobulin M (IgM) directed towards Salmonella typhi (S. typhi) antigen remains controversial despite its popularity. This study was aimed to assess the validity of IgM anti S. typhi serologic test in childhood typhoid fever. Methods: This retrospective diagnostic test, used blood culture as gold standard. Forty-one typhoid fever children with fever of 1â14 days admitted to Dr. Hasan Sadikin General Hospital Bandung from 2013 to 2015 were recruited. Diagnosis of typhoid fever is made clinically. Data were analyzed by Receiver Operating Characteristic (ROC) curve and diagnostic test.Results: Forty one children diagnosed with typhoid fever, 37 were positive for IgM anti S. typhi, but only 18 were positive for S. typhi in blood culture. IgM anti S. typhi (cut-off â¥4) test had an Area Under the Curve (AUC) of 59%, sensitivity of 100% and specificity of 17.39%. IgM anti S. typhi with cut-off >8 showed the highest AUC with sensitivity of 55.56% and specificity of 73.68%.Conclusions: IgM anti S. typhi test of cut-off >8 performs better than cut-off â¥4 in terms of AUC..[AMJ.2017;4(1):138â42] DOI: 10.15850/amj.v4n1.1035]]>
