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Althea Medical Journal
Published by Universitas Padjadjaran
ISSN : -     EISSN : 23374330     DOI : 10.15850/amj
Core Subject : Health,
Medicine & Pharmacology
Althea Medical Journal (AMJ) is a peer reviewed electronic scientific publication journal which is published every 3 months (March, June, September, and December). Althea Medical Journal publishes articles related to research in biomedical sciences, clinical medicine, family-community medicine, and public health.
Arjuna Subject : -
Articles 1,068 Documents
 69   70   71   72   73 
Clinical and Histopathological Characteristics of Psoriasis in Dr. Hasan Sadikin General Hospital Bandung from 2009 to 2013 Willy Chandra Hermawan; Hermin Aminah; Dendi Sandiono
Althea Medical Journal Vol 3, No 4 (2016)
Publisher : Faculty of Medicine Universitas Padjadjaran

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Abstract

Background: Psoriasis is a chronic inflammatory skin disease characterized by alterations in epidermal growth and differentiation. Its primary cause remains unknown, and its clinical and histopathological characteristics sometimes change from time to time. The study aimed to reveal the clinical and histopathological characteristics among psoriasis patients in Dr. Hasan Sadikin General Hospital Bandung.Methods: This study involved 162 medical records of psoriasis patients who visited the Department of Dermato-Venereology and 40 medical records of psoriasis patients who visited the Department of Pathological Anatomy of Dr. Hasan Sadikin Hospital, from 2009 to 2013. Medical record data were collected to describe the patient’s clinical and histopathological characteristics of psoriasis. The collected data were analyzed by frequency distribution.Results: From the clinical medical records, the characteristics found among the psoriasis patients were: 14 (8.6%) having familial history, 160 (98.8%) having reddish plaque, 155 (95.7%) having silvery scale, 40 (24.7%) having pustules, 6 (3.7%) having positive Auspitz sign, 48 (29.6%) having nail involvement, and 20 (12.4%) having tongue involvement. In addition, from the histopathological medical records, the characteristics of epidermis among the psoriasis patients found were: 36 (90%) having hyperkeratosis with parakeratosis, 39 (98%) having rete ridge elongation and/or acanthosis, 35 (88%) having Munro’s microabcess and/or micropustules of Kogoj, 15 (38%) having thin stratum granulosum, and 30 (75%) having blood vessels dilatation.Conclusions: In psoriasis, the most common clinical characteristics are reddish plaque while the most common histopathological characteristics are elongation of the rete ridges and/or acanthosis. [AMJ.2016;3(4):556–61] DOI: 10.15850/amj.v3n4.938
Hyperuricemia and Proteinuria in Type 2 Diabetic Patients Fatya Annisa Haryandini; Tiene Rostini
Althea Medical Journal Vol 2, No 1 (2015)
Publisher : Faculty of Medicine Universitas Padjadjaran

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Abstract

   Background: Type 2 diabetes mellitus is a metabolic disorder that has diabetic nephropathy as a complication characterized by proteinuria. When type 2 diabetic patient’s kidney is damaged, hyperuricemia occurs. This study evaluated the correlation of serum uric acid and proteinuria levels in type 2 diabetic patients from outpatient Endocrine clinic at Dr. Hasan Sadikin General Hospital from January to December 2011.Methods: In a cross-sectional study of 125 patients (55 male and 70 female) with type 2 diabetes mellitus, the data of serum uric acid, fasting plasma glucose, 2-h post oral glucose load plasma glucose, serum high-density lipoprotein cholesterol, serum trygliceride, and proteinuria levels were accessed from the medical record. Spearman test was used to calculate the correlation of serum uric acid and proteinuria levels. The research used secondary data taken from medical records  of patients diagnosed with T2DM  from outpatient Endocrine clinic of Internal Medicine Department at Dr. Hasan Sadikin General Hospital Bandung who had alaboratory examination at Department of Clinical Pathology of Dr. Hasan Sadikin General Hospital Bandung from January to December 2011.Results: The mean age of the type 2 diabetic patients was 61.5±9.2 years old, with mean serum uric acid level of 6.2±1,8 mg/dl, of whom 52.8% had microalbuminuric and 4.8% had proteinuria. In type 2 diabetic patients, serum uric acid level correlated positively (r=0.273) with proteinuria (p=0.002).Conclusions: Higher serum uric acid levels associated significantly positive with a greater probability of proteinuria in type 2 diabetic patients, indicating a potential marker for disease severity.Keywords: Proteinuria, type 2 diabetes mellitus, uric acidDOI: 10.15850/amj.v2n1.430 
Relation between Preinfarction Angina and Coronary Collateral Circulation in Patients with Acute Myocardial Infarction Achmad Shidiq; Syarief Hidayat; Januarsih Iwan Rachman
Althea Medical Journal Vol 3, No 1 (2016)
Publisher : Faculty of Medicine Universitas Padjadjaran

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Abstract

Background: Coronary collateral circulation conduits an alternative blood flow to the ischemic myocardium in the setting of coronary artery occlusion which can prevent the infarction area to extend more widely. Well-developed coronary collaterals are closely related with the presence of preinfarction angina. However, the duration of preinfarction angina which can induce well-developed coronary collateralization is in controversy. The aim of this study was to evaluate the relation between duration of preinfarction angina and coronary collaterals circulation in patients with acute myocardial infarction.Methods: This cross-sectional study was conducted from May to November 2013 in Dr. Hasan Sadikin General Hospital, Bandung, Indonesia. Seventy three acute myocardial infarction (AMI) patients were included in the study. The patients were divided into Group 1 (<7 days) and Group 2 (≥7 days) based on their preinfarction angina history. The coronary collaterals were assesed and graded as good (Rentrop score 2−3) and poor (Rentrop score 0−1).Statistical analysis was performed using the chi-square test.Result: The presence of a well-developed coronary collateral was not significantly different in <7days than ≥7 days duration of preinfarction angina [50.8% v 75.0%, p=0.124].Conclusions: There is no relation between the duration of preinfarction angina and coronary collaterals circulation in patients with acute myocardial infarction. [AMJ.2016;3(1):28–33]DOI: 10.15850/amj.v3n1.709
Association between Patient’s Basic Characteristic and Clark Level in Cutaneous Malignant Melanoma Egie Rahmalaelani; Hermin Aminah Usman; Jono Hadi Agusni
Althea Medical Journal Vol 4, No 1 (2017)
Publisher : Faculty of Medicine Universitas Padjadjaran

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Abstract

Background: Malignant melanoma is  a cancer that begins in the melanocytes. Melanoma is commonly happened on older people, male and located on sun exposure body area, such as face, neck and lower limb. Melanoma cases occur less than 5% of skin cancer but cause a majority of skin cancer deaths because melanoma has an aggressive behavior. Age, sex, location of lesion, and type of melanoma influences the melanoma invasion. The cutaneous melanoma invasion could be assessed with the Clark level. This study is aimed to determine the association between patient’s basic characteristic and Clark level in cutaneous malignant melanoma.Methods: This study used cross sectional analytic design. The medical records and histopathology slide from the Department of Anatomic Pathology Dr. Hasan Sadikin General Hospital from 2008−2012 took as a sample. Forty one data were meet the inclusion criteria.  Furthermore, those data were analyzed using chi-square test.Result: Overall, patient’s characteristic in this study, commonly occurred on female (66%), 50−59 years group age (35%), non-cephalic/acral location (71%), and the level V in Clark level (73%). Location of lesion showed an association with Clark level (p=0.023), whereas, age and sex was not significant (p=0.679 and p=0.389).Conclusions: There is an association between location of lesion and Clark level [AMJ.2017;4(1):25–9]DOI: 10.15850/amj.v4n1.1015 
Clinical Profile and Mortality in Children with Pneumonia Ashvinii Manivel; Sri Sudarwati; RB. Soeherman Herdiningrat
Althea Medical Journal Vol 2, No 2 (2015)
Publisher : Faculty of Medicine Universitas Padjadjaran

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Abstract

Background: Pneumonia is the leading killer in under-five children. Therefore, by identifying the danger signs, we are able to predict children who are at higher risk of mortality. The objective of the study is to identify the relationship between the clinical profile and mortality in children with pneumonia at Dr. Hasan Sadikin General Hospital, Bandung.Methods: This was an analytical study with a retrospective case control approach using medical records with patient’s age limitation of 1–60 month. The study period started on January 1st 2010 and ended on December 31st 2011. All types of pneumonia included whereas congenital anomalies, immunocompromised and Down’s syndrome patients were excluded in this study. Data were presented as frequency distribution.Results: During the study period, there were 653 children under age of 5 with pneumonia. Only 56 subjects met the inclusion and exclusion criteria. Twenty-eight patients with pneumonia were cured and 28 died. Based on the phi’s coefficient, tachycardia (α-value = 0.019) and hepatomegaly (α-value = 0.001) were significant predictors of death and based on the Mantel-Haenszel analysis, hepatomegaly (OR=9.62, CI 95% 2.349–39.35) was significant as a risk for mortality. Inability to drink, cyanosis, tachypnea, grunting, vomiting, convulsion, and unconsciousness were not related to mortality.Conclusion: Tachycardia and hepatomegaly have a significant relationship with mortality in under-five children with pneumonia. [AMJ.2015;2(1):235–40]
Knowledge, Attitude, and Practice on Food Safety among Senior High School Students in Jatinangor from August−November 2013 Hamizah Sabrina Binti Ahamad Naina; Ine Kuswardinah; Sumartini Dewi
Althea Medical Journal Vol 3, No 2 (2016)
Publisher : Faculty of Medicine Universitas Padjadjaran

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Abstract

Background: Food safety is defined as the confidence level that food will not cause sickness or harm to consumer when it is prepared, served, and eaten according to its intended use. This study was conducted to describe the pattern of knowledge, attitude, and practice on food safety among high school students in Jatinangor.Methods: One hundred and two respondents were involved in this study. The data were collected from the high school students in Jatinangor, West Java from August to November 2013 through the methods of questionnaire after the informed consent was obtained from the respondents. The questionnaire was translated from the Five Keys to Safer Food Manual by World Health Organization. The collected data were then presented in percentage.Results: Overall, 60.78% of respondents had moderate knowledge, 85.29% had good attitude, and 71.57% had good practice in food safety. Among the five main points on food safety in all aspects, most of the respondents were unaware of the safe temperature to store food; hence, they did not practice it.Conclusions: Even though most of the students have the knowledge, attitude, and practice on food safety, a need for relevant and motivating education should be performed for spesific indicators of food safety. [AMJ.2016;3(2):206–11]DOI: 10.15850/amj.v3n2.797
Antimicrobial Sensitivity of Neonatal Bacterial Sepsis Nadya Iswandari; Aris Primadi; Sunarjati Sudigdoadi
Althea Medical Journal Vol 4, No 2 (2017)
Publisher : Faculty of Medicine Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (183.214 KB) | DOI: 10.15850/amj.v4n2.1072

Abstract

Background: Appropriate treatment on neonatal bacterial sepsis is important based on the exact etiology to prevent bacterial resistance, but bacterial identification using blood cultures requires a considerable time. The newest data of various bacteria and their sensitivity can be used to assist empirical antibiotics usage. This study was conducted to identify bacterial profile that caused neonatal sepsis and their sensitivity to antibiotics at Dr. Hasan Sadikin General Hospital Bandung..Methods: A total of 275 neonatal sepsis cases and 288 blood cultures results were collected from a database provided by Dr. Hasan Sadikin General Hospital Bandung during the period of July 2011 toDecember 2012 (three semesters).  Etiology of the bacteria and antimicrobial sensitivity profile data were taken from positive bacteria results. Then, these variables were processed using the descriptive method and classified by semesterResult: The most common bacteria that caused neonatal sepsis in the second semester 2011 is Serratia marescens, the first semester 2012 was Enterobacter aerogenes and in the second semester 2012 was Burkholderia cepacia. The most sensitive antibiotics were piperacillin tazobactam, cefepime, meropenem and amikacin in all three semesters, gentamycin in the second semester 2011 and 2012, and amoxicillin clavulanic in the second semester 2012.Conclusions: Bacterial and antimicrobial sensitivity profile is varied in every semester.Keywords: Antimicrobial sensitivity profile, bacterial profile, neonatal sepsisDOI: 10.15850/amj.v4n2.1072
Barriers to Smoking Cessation among Medical Students 2012–2013 Academic Year in the Faculty of Medicine, Universitas Padjadjaran Reni Yuditha Kathrine; Elsa Pudji Setiawati; Lucky Saputra
Althea Medical Journal Vol 2, No 3 (2015)
Publisher : Faculty of Medicine Universitas Padjadjaran

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Abstract

Background: Smoking is one of leading various diseases and even death globally.  It is often difficult for smokers to stop smoking, even those who work as a medical professional because there are some barriers around them. The objective of this study was to get an overview of the barriers to smoking cessation among smoker students of Faculty of Medicine, Universitas Padjadjaran.Methods: A descriptive study was carried out to 62 medical students 2012–2013 academic year in the Faculty of Medicine, Universitas Padjadjaran. Before the respondents were selected, a survey using questionnaire was conducted to all medical students from the same academic year to determine their smoking status. A set of questions was developed, consisted of 4 components: physical or social, psychological or emotional, accessibility, and social contextual/life circumstances barriers to smoking cessation. The collected data were analyzed and presented in the form of percentages shown in the tables and figures.Results: The most frequent barriers were from physical or social barriers (friends who smoke, 85%), psychological or emotional barriers (fear of losing enjoyment, 71%), barrier to access (lack of information about the way of smoking cessation, 42%) and social contextual/life circumstances barriers (having other priorities other than to stop smoking, 71%).Conclusions: There are some barriers in medical students smokers make them difficult to stop smoking although they have more knowledge about health and the impact of smoking on health than other people. DOI: 10.15850/amj.v2n3.561
Tinea Capitis among Elementary School Students in Jatinangor,Sumedang, West Java Dilla Aprilia; Lies Marlysa Ramali; Ramlan Sadeli
Althea Medical Journal Vol 3, No 3 (2016)
Publisher : Faculty of Medicine Universitas Padjadjaran

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Abstract

Background: Fungal infection is a common disease in tropical and subtropical countries. Warm and humid climates provide a favourable environment for organism causing superficial mycosis. One of the fungal infections that commonly occurred in children is tinea capitis. Tinea capitis is a superficial fungal infection of the hair and scalp caused by dermatophytes. The age predilection of this disease is children aged 3 until 14 years . The purpose of this study was to detect the presence of tinea capitis among elementary school students in Jatinangor, Sumedang, Indonesia.Methods: This cross-sectional descriptive study involved 391 students from thefirst until sixth grade at four elementary schools in Jatinangor, in the period of September until October 2013. Anamnesis, physical examination, Wood’s lamp examination and direct microscopic examination were conducted to diagnose the disease. The collected data were analyzed and presented in the form of frequency distribution and percentages shown in tables.Results: Out of 391 students participating in this study, 194 were boys and 197 were girls. The age range was 6 until 16 years. Based on the screening results, 74 students were known to have complaints about their hair and scalp and only 49 students could continue the study as they have no positive result of tinea capitis.Conclusions: There is no positive findings of tinea capitis according to anamnesis, physical examination, Wood’s lamp examination and direct microscopic examination. Further examination by culture with Sabouraud’s dextrose agar should be carried out. [AMJ.2016;3(3):340–4] DOI: 10.15850/amj.v3n3.876
Association of Obesity, Parity, and History of Knee Injury with Knee Osteoarthritis in Female Ade Triyadi; Riardi Pramudiyo; Januarsih Iwan A. R.
Althea Medical Journal Vol 2, No 4 (2015)
Publisher : Faculty of Medicine Universitas Padjadjaran

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Abstract

Background: Osteoarthritis is the most joint disorder among elderly. There are a lot of risk factors of knee osteoarthritis. Obesity and high frequent of parity can increase the load on knee joint. Knee injury also decreases the stability of knee joint on bearing body load. This study was conducted to observe the association of obesity, parity ≥3 times and history of knee injury with the occurrence of knee  osteoarthritis in female aged >50 years old.Methods: Case control design was chosen in this study. Female patients with age >50 years were recruited by consecutive sampling from rheumatology clinic at Dr. Hasan Sadikin General Hospital Bandung. Data were collected from August to September 2013. Minimal sample size was 60 samples calculated by rule of thumb formula. Obesity was measured by body mass index (BMI). Parity and history of knee injury were assessed by questionnaire. Those variables were analyzed by logistic regression method.Result: Obesity did not associate with knee osteoarthritis in this study, p=0.549 (odd ratio (OR) 1.32, 95% confidence interval (CI) 0.52–3.32). Parity was associated with knee osteoarthritis in this study p=0.001 (OR 4.7, 95% CI 1.89–11.68). History of knee injury was associated with knee osteoarthritis in this study, p=0.001 (OR 6.19, 95% CI 2.01–18.99).Conclusions: Parity ≥3 times and history of knee injury were associated with the occurrence of knee osteoarthritis. Obesity was not associated with the occurrence of knee osteoarthritis. [AMJ.2015;2(4):492–6] DOI: 10.15850/amj.v2n4.633

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