cover
Article Per Year (5 Year)
All
Home Page
OAI Link
Editorial Team
Contact
Reviewer
Google Scholar
Contact Name
Isna Rasdianah Aziz
Contact Email
isna-rasdianah@uin-alauddin.ac.id
Phone
+6285242001984
Journal Mail Official
biogenesis@uin-alauddin.ac.id
Editorial Address
Department of Biology, Faculty of Science and Technology, Universitas Islam Negeri Alauddin Makassar. Jl. H.M. Yasin Limpo No. 36 Samata, Gowa, South Sulawesi, Indonesia. 92113
Location
Kab. gowa,
Sulawesi selatan
INDONESIA
Biogenesis: Jurnal Ilmiah Biologi
Published by Universitas Islam Negeri Alauddin Makassar
ISSN : 23021616     EISSN : 25802909     DOI : https://doi.org/10.24252/bio
Core Subject : Science, Agriculture,
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Immunology & microbiology
Biogenesis: Jurnal Ilmiah Biologi is a peer-reviewed and open-access journal that publishes original scientific work with the advancement of tropical bioscience in Asia. The integration between Islam and tropical bioscience explicitly represents the Biogenesis: Jurnal Ilmiah Biologi as an academic publication for Islamic scientists, which could contribute to the advancement of tropical biology studies in the Islamic world. The journal invites research articles, short communication, critical and comprehensive scientific reviews concerning tropical biosciences in Asia, specifically in the following subjects: Islamic-integrated tropical bioscience Tropical biodiversity and conservation Biosystematics of tropical species Biochemistry and physiology of tropical species Ecological study and behavior of tropical species Tropical genetics, biotechnology, and bioinformatics
Arjuna Subject : Ilmu Pertanian dan Biologi (Semua) - Ilmu Pertanian dan Biologi (Lain-Lain)
Articles 14 Documents
 1   2 
Search results for , issue "Vol 12 No 2 (2024)" : 14 Documents clear
Studi In Vitro dan In Silico pada Ekstrak Bonggol Pisang Kepok sebagai Anti-tirosinase Andini, Andini; Raharjo, Sentot Joko; Misgiati, Misgiati; Izza, Aqidatul; Istiana, Meiria
Biogenesis: Jurnal Ilmiah Biologi Vol 12 No 2 (2024)
Publisher : Department of Biology, Faculty of Sci and Tech, Universitas Islam Negeri Alauddin Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24252/bio.v12i2.53561

Abstract

Tyrosinase is a critical enzyme in melanin synthesis, where its overactivity can result in hyperpigmentation disorders. Despite the availability of synthetic tyrosinase inhibitors, concerns about safety have prompted the search for natural alternatives. The objective of this study is to evaluate the potential of Kepok banana (Musa acuminata x balbisiana) corm extract as a natural tyrosinase inhibitor, using in vitro and in silico approaches. The extract was prepared by maceration with etanol 96%, followed by sonication and lyophilization. LC-MS analysis was performed on a Shimadzu LCMS 8040 using a Shim Pack FC ODS column with 90% methanol as the mobile phase under isocratic conditions. Samples were ionized via ESI in positive mode and scanned over m/z 10–1000. Peaks were identified based on their m/z values and MS/MS fragmentation patterns. In vitro and in silico analyses were applied, respectively, to study the biological process of kepok banana corm extract as a natural tyrosinase inhibitor. The result of the kepok banana corm extraction process was 12.5% dry powder with bioactive components identified via LC-MS, including flavonoids, phenolics, and terpenoids. The kepok banana corm ethanol extract exhibited strong tyrosinase inhibition with an IC₅₀ of 91.074 µg/mL, falling below the 100 µg/mL threshold for strong inhibitors and showing a similar inhibition pattern to the standard kojic acid (IC₅₀ = 10.87 µg/mL). Molecular docking revealed that major compounds, particularly flavonoids, exhibited high binding affinity with the tyrosinase enzyme through hydrogen bonding and hydrophobic interactions, similar to kojic acid, a known inhibitor. These findings suggest that kepok banana corm extract may serve as a promising natural tyrosinase inhibitor, with potential applications in hyperpigmentation treatment and cosmetic formulations.
Plant diversity and its conservation status in the Gunung Pujut Ancient Mosque Area, Lombok Island, Indonesia Rahayu, Slamet Mardiyanto; Mappanganro, Nurlailah; Da Costa, Luis; Hakim, Luchman; Batoro, Jati; Sukenti, Kurniasih
Biogenesis: Jurnal Ilmiah Biologi Vol 12 No 2 (2024)
Publisher : Department of Biology, Faculty of Sci and Tech, Universitas Islam Negeri Alauddin Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24252/bio.v12i2.57038

Abstract

Gunung Pujut Ancient Mosque is one of the cultural heritages in Lombok Island. This study aims to determine the diversity and conservation status of plants in the Gunung Pujut Ancient Mosque area. The research was conducted through direct observation, calculation of diversity index and dominance index, and tracing the conservation status of plant species. There are 29 families, 31 genera, and 34 plant species in the Gunung Pujut Ancient Mosque area. This is a stable ecosystem because it has a high diversity of plants. This shows that the cultural heritage area of the Gunung Pujut Ancient Mosque is a suitable habitat for the growth and development of various plant species and plays a role in supporting biodiversity conservation. There is no ecological pressure in this area because it has low plant dominance index.
Analysis the ability of Alphitobius diaperinus larvae as biodegradator of potato peel waste Diennurrahma, Aufa; Widiyaningrum, Priyantini; Indriyanti, Dyah Rini; Ngabekti, Sri
Biogenesis: Jurnal Ilmiah Biologi Vol 12 No 2 (2024)
Publisher : Department of Biology, Faculty of Sci and Tech, Universitas Islam Negeri Alauddin Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24252/bio.v12i2.58503

Abstract

The larvae of Alphitobius diaperinus (lesser mealworms) are often regarded as pests in livestock farms; however, they possess significant potential as waste biodegraders due to their chewing mouthparts, strong jaws, and symbiotic microbes in their digestive tracts. This study investigates their ability to biodegrade potato peel waste. A Completely Randomized Design (CRD) was employed with three treatment groups: P0 (50 grams of pollard), P1 (50 grams of pollard plus 35 grams of fresh potato peel waste), and P2 (50 grams of pollard plus 5 grams of dried potato peel waste). Third instar larvae were selected based on uniform size, color, and weight. The experiment was conducted over 10 weeks, with weekly monitoring of larval development. The results indicated that A. diaperinus larvae effectively biodegraded potato peel waste, with the highest waste reduction and Waste Reduction Index (WRI) observed in the P1 group. Quantitative data showed that the WRI for P1 (8.87%) was significantly higher than that of P2 (2.94%). Biomass production was analyzed using the non-parametric Kruskal-Wallis test, revealing significant differences between groups P0 and P1, while no significant differences were found between P0 and P2 or between P1 and P2. In conclusion, A. diaperinus larvae demonstrate considerable potential as biodegraders of potato peel waste. Moreover, the combination of potato peel and pollard as a rearing substrate positively influences larval biomass production.
Identifikasi dan Analisis Senyawa Kimia pada Ekstrak Daun Murbei (Morus alba) Melalui Skrining Fitokimia dengan Metode Spektrofotometer Wati, Dwi Kartika; Achyar, Zhahrotun Khofifah Nur; Aziza, Nur; Mudzakaroh, Luluk; Pratiwi, Lidia Wahyu; Paramitha, Armanda Bella; Ramadhan, Majida; Nafisa, Nafisa; Mahyantika, Seftya
Biogenesis: Jurnal Ilmiah Biologi Vol 12 No 2 (2024)
Publisher : Department of Biology, Faculty of Sci and Tech, Universitas Islam Negeri Alauddin Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24252/bio.v12i2.58677

Abstract

Mulberry leaves (Morus alba Linn.) are a plant whose potential has been widely studied because it contains phytochemical compounds such as flavonoids and phenols which have various health benefits. This plant belongs to the Moraceae family and has the characteristics of a woody trunk, branches and brown bark with a height of between 5 and 10 meters, has oval or heart-shaped leaves with tapered tips, and has oval-shaped fruit that is black when ripe. This research aims to analyze chemical compounds in mulberry leaf extract (Morus alba L.) using spectrophotometric methods. Phytochemical screening showed positive results for flavonoids (Shinoda and NaOH test), alkaloids (Wagner and Dragendorff test), tannins (Braymer's solution and base) test, and steroids (Salkowski test). UV-Vis spectrophotometric analysis at a wavelength of 200-800 nm shows maximum absorption at 786 nm for the 10-2 dilution sample. Analysis of total flavonoid content using standard quercetin showed concentrations of 50.06 mg/g and 52.87 mg/g for the 1000 ppm and 500 ppm samples, respectively. The extract yield was 29.086%, with a water content of 4.415% and an ash content of 0.1%. These findings indicate that mulberry leaf extract contains various bioactive compounds with potential pharmacological properties, especially flavonoids which can be useful for medicinal applications.

Page 2 of 2 | Total Record : 14

 1   2 

Filter by Year

2024 2024


Reset
Filter By Issues
All Issue Vol 13 No 1 (2025) Vol 12 No 2 (2024) Vol 12 No 1 (2024) Vol 11 No 2 (2023) Vol 11 No 1 (2023) Vol 10 No 2 (2022) Vol 10 No 1 (2022) Vol 9 No 2 (2021) Vol 9 No 1 (2021) Vol 8 No 2 (2020) Vol 8 No 1 (2020) Vol 7 No 2 (2019) Vol 7 No 1 (2019) Vol 6 No 2 (2018) Vol 6 No 1 (2018) Vol 5 No 2 (2017) Vol 5 No 1 (2017) Vol 4 No 2 (2016) Vol 4 No 1 (2016) Vol 3 No 2 (2015) Vol 3 No 1 (2015) Vol 3, No 1 (2015) Vol 2 No 2 (2014) Vol 2, No 2 (2014) Vol 2 No 1 (2014) Vol 2, No 1 (2014) Vol 1, No 2 (2013) Vol 1 No 2 (2013) Vol 1, No 1 (2013) Vol 1 No 1 (2013) More Issue