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INDONESIA
Journal of Mathematical and Fundamental Sciences
ISSN : 23375760     EISSN : 23385510     DOI : https://doi.org/10.5614/j.math.fund.sci.
Core Subject : Science, Education,
Journal of Mathematical and Fundamental Sciences welcomes full research articles in the area of Mathematics and Natural Sciences from the following subject areas: Astronomy, Chemistry, Earth Sciences (Geodesy, Geology, Geophysics, Oceanography, Meteorology), Life Sciences (Agriculture, Biochemistry, Biology, Health, Medical, Pharmacy), Mathematics, Physics, and Statistics.
Articles 689 Documents
The Modified Double Sampling Coefficient of Variation Control Chart Fachrur Rozi; Udjianna Sekteria Pasaribu; Utriweni Mukhaiyar; Dradjad Irianto
Journal of Mathematical and Fundamental Sciences Vol. 55 No. 1 (2023)
Publisher : Directorate for Research and Community Services (LPPM) ITB

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.5614/j.math.fund.sci.2023.55.1.4

Abstract

The concept of monitoring the coefficient of variation has gained significant interest in quality control, particularly in situations where the mean and standard deviation of a process are not constant. This study modified the procedure of the previous double sampling chart for monitoring the coefficient of variation, developed by Ng et al. in 2018. Instead of using only information from the second sample, here, information from both samples is used. The probability properties of the out-of-control signal and run length of this chart are presented. To evaluate the chart’s performance, the optimal design and a comparison with the previous double sampling control chart using average run-length criteria are described. It was found that the modified double sampling chart has better performance and is more efficient compared to the previous chart, especially when the total sample size is smaller. As a study case, the application of this chart is illustrated using real data from a molding process. This confirmed that the modified double sampling chart improved performance in detecting out-of-control signals. Thus, the modified chart is recommended to be applied in industry.
Applying Fluorescence Dissolved Organic Matter Spectra and Phytoplankton Biology Index for Assessing Urban River Quality Okik Hendriyanto Cahyonugroho; Sucipto Hariyanto; Ganden Supriyanto
Journal of Mathematical and Fundamental Sciences Vol. 54 No. 3 (2023)
Publisher : Directorate for Research and Community Services (LPPM) ITB

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.5614/j.math.fund.sci.2023.54.3.3

Abstract

The relationship between phytoplankton dynamics and dissolved organic matter (DOM) in aquatic systems based on fluorophore organic matter properties results in poor implementation of methods for water quality monitoring. This study aimed to investigate the relation between fluorophore organic matter and phytoplankton index and to estimate the phytoplankton index by fluorescent organic components for water quality assessment. The research was conducted by sampling urban river water, followed by measuring the biological phytoplankton index and dissolved organic matter during the wet and dry seasons. Fluorescence Excitation Emission Matrices (FEEMs) analysis combined with Parallel Factor (PARAFAC) analysis identified three main components of the fluorescence organic matter, i.e., a fulvic acid-like component (C1) and humic acid-like components (C2 and C3), in the aquatic system, whether in the dry season or the wet season. C1 was mainly generated by phytoplankton species, i.e., Nitzschia sp., Plectonema sp., Navicula sp., and Pinnularia sp., and C2 and C3 had a less significant relationship with phytoplankton species. The diversity of Bacillariophyta had a stronger contribution to the release of DOM than the diversity of Cyanobacteria. The abundance index of a particular phytoplankton species can be used to determine the organic components of FEEM-derived fluorescence organic matter.
Carbon Nanodots as Complexing Agent in the Formation of Lead(II) Sulfide Thin Films via Direct Deposition of Lead(II) Sulfide Powder Ariswan Ariswan; Bian Itsna Ashfa Al Ashfiya; Anisha Nurcahyati; Wipsar Sunu Brams Dwandaru
Journal of Mathematical and Fundamental Sciences Vol. 55 No. 1 (2023)
Publisher : Directorate for Research and Community Services (LPPM) ITB

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.5614/j.math.fund.sci.2023.55.1.1

Abstract

This study reveals for the first time the formation of lead(II) sulfide (PbS) thin films via direct deposition of PbS powder using carbon nanodots (Cdots) as a complexing agent. The chemical bath deposition (CBD) technique was utilized and the Cdots’ mass was varied, i.e., (in g) 3, 5, 7, and 9. The Cdots were prepared from the waste of a rice noodle production home industry via the low-temperature carbonization method. The Cdots were characterized using UV-Vis spectrophotometry, showing absorption peaks at 275 nm and 325 nm; PL, showing an emission peak at 500 nm with cyan luminescence; XRD, showing several peaks, indicating an incomplete carbonization process; FTIR, indicating the existence of C=C, C-H, C-O, and O-H functional groups; HRTEM, revealing the sizes of the Cdots in the range of 2 nm to 6 nm; and SEM, showing a smooth morphology of the Cdots’ surface. The thin films obtained were smooth with higher XRD peaks and better material distribution compared to pure PbS thin film. The band gap measurement indicated that the increase of the PbS band gap was caused by the increase of the Cdots’ mass. Hence, the thin films’ band gap may be tuned using the Cdots’ mass.
Havanensin-type Limonoids from the Stem Bark of Chisocheton pentandrus (Meliaceae) Dudi Runadi; Purnama Purnama; Supriatno Salam; Nulelasari Nurlelasari; Desi Harneti; Tri Mayanti; Rani Maharani; Unang Supratman; Yoshihito Shiono
Journal of Mathematical and Fundamental Sciences Vol. 54 No. 3 (2023)
Publisher : Directorate for Research and Community Services (LPPM) ITB

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.5614/j.math.fund.sci.2023.54.3.2

Abstract

A new limonoid, belonging to the havanensin-type, called pentandricine E (1), alongside four other known types, i.e., trichilenone acetate (2), toonaciliatones C (3), 11α-acetoxyazadirone (4) and ceramicine I (5), were found in Chisocheton pentandrus stem bark. The structures of the isolated 1-5 were identified by NMR spectroscopy and HRTOFMS. Pentandricine E (1) displayed the highest cytotoxicity toward the MCF-7 breast cancer line with an IC50 value of 63.27 ± 0.21 mM.
Shallow S-wave Velocity Profile Estimation using Surface Velocity and Microtremor HVSR with a Linear Velocity Increase Approach Andi Muhamad Pramatadie; Hiroaki Yamanaka; Afnimar Afnimar
Journal of Mathematical and Fundamental Sciences Vol. 54 No. 3 (2023)
Publisher : Directorate for Research and Community Services (LPPM) ITB

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.5614/j.math.fund.sci.2023.54.3.4

Abstract

We propose a simple method for 1D S-wave velocity (Vs) profile estimation using a measured surface S-wave velocity (V1) and peak frequency of the observed microtremor horizontal-to-vertical spectral ratio (HVSR). In this method, the S-wave velocity profile is presented as linear velocity increase with depth in sediments over a bedrock layer that has a given constant S-wave velocity. Thus, the profile can be parameterized with the measured surface S-wave velocity and the velocity gradient. The gradient can be estimated based on the agreement of the peak frequencies of the observed microtremor HVSR and the theoretical ellipticity of the fundamental mode of the Rayleigh wave. We examined the applicability of the proposed method using numerical tests as well as application to actual data at five sites in the Bandung Basin, Indonesia, where observed Rayleigh wave phase velocities from microtremor array surveys were available. The applicability was confirmed in numerical tests using sample models of soil profiles in the basin. Actual application indicated the appropriateness of the estimated S-wave velocity profiles due to the similarity of their theoretical Rayleigh wave phase velocities with the observed Rayleigh wave phase velocities. Since the proposed method needs prior confirmation of the linear increase of the S-wave velocity, it is suitable for use in spatial interpolation of shallow S-wave velocity profiles with simple data acquisition.
Modelling the Impact of Decomposed Disease-Induced Dead Cashew Plants on Fusarium Wilt Dynamics in South-Eastern Tanzania Fatu Chilinga; Alfred K. Hugo
Journal of Mathematical and Fundamental Sciences Vol. 55 No. 1 (2023)
Publisher : Directorate for Research and Community Services (LPPM) ITB

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.5614/j.math.fund.sci.2023.55.1.3

Abstract

Cashew Fusarium wilt disease transmitted by Fusarium oxysporum is dangerous and destroys many cashew plants in Tanzania. The effect of this disease leads households and the government to experience a decrease in overall cashew production and income due to this disease’s capacity to harm cashew plants. This study aimed to ascertain the role of Fusarium wilt-decayed disease-induced dead plants in spreading the disease among cashew plants. A mathematical model was created based on the dynamics of the disease and a stability analysis was conducted using theories of ordinary differential equations. Data from two regions in Tanzania, Lindi, and Mtwara, were used in model fitting and parameter estimation. Additionally, the parameters were estimated using maximum likelihood estimation (MLE). The outcome suggests that the disease’s prevalence and spread increase during an outbreak as decomposed diseased-induced dead plants contribute to the saturation of chlamydospores in the soil.
Magnetoresistance Features at the Magnetic Field-Induced Phase Transition in FeRh Thin Films Aleksei S. Komlev; Rodion A. Makarin; Viktoria E. Maltseva; Vladimir I. Zverev; Alexey S. Volegov; Nikolai S. Perov
Journal of Mathematical and Fundamental Sciences Vol. 55 No. 1 (2023)
Publisher : Directorate for Research and Community Services (LPPM) ITB

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.5614/j.math.fund.sci.2023.55.1.2

Abstract

The causes of the appearance of first-order magnetic phase transitions remain a mystery. FeRh alloy is a classical material where a first-order magnetic phase transition occurs. The authors of this article studied the phase transition from the antiferromagnetic state to the ferromagnetic state in FeRh alloy. Comparison of the magnetometry and transport properties results allowed us to determine a number of differences in the mechanisms of the phase evolution during magnetic field and temperature induced transition. This article notes the priority of the rearrangement of the micromagnetic structure of the ferromagnetic phase as a result of the induction of a phase transition by a magnetic field. The main feature of the magnetic field induced phase transition compared to the temperature induced one is the change in the micromagnetic structure of the ferromagnetic phase. The growth of a ferromagnetic phase with less scattering fields leads to asymmetric behavior when a phase transition is induced near the metastable state. We also focused on the importance of taking into account the effect of magnetostriction when analyzing the evolution of the phase transition, which leads to the irreversibility of the phase transition near a zero magnetic field.
Computational Study of Nocardiotide-A Analogues in the Development of Technetium-99m Radiopeptides for Cancer Imaging for Targeting Somatostatin Receptor 2 Rizky Juwita Sugiharti; Rani Maharani; Rahmana Emran Kartasasmita; Daryono Hadi Tjahjono
Journal of Mathematical and Fundamental Sciences Vol. 55 No. 1 (2023)
Publisher : Directorate for Research and Community Services (LPPM) ITB

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.5614/j.math.fund.sci.2023.55.1.5

Abstract

Nocardiotide-A (cWIWLVA) is a cyclic peptide with significant cytotoxicity against several cancer cells. The present research aimed to design a radiopeptide based on nocardiotide-A analogues to be labeled by technetium-99m targeting SSTR2, which is the most widely expressed receptor in several types of human cancers and used as radiopeptide target. Nocardiotide-A analogues were individually designed by replacing valine at the lead compound with lysine, arginine, histidine, asparagine, and glutamine, and this was simulated by molecular dynamics using AMBER18. A molecular docking using AutoDock 4.2 was performed and evaluated to understand the effect of chelation of technetium-99m on 99mTc-HYNIC-EDDA and 99mTc-HYNIC-tricine on the binding affinity of nocardiotide-A analogues. The molecular dynamics simulation confirmed that the designed nocardiotide-A-based peptides were stable in the binding pocket of SSTR2 for 200 ns. Moreover, the nocardiotide-A-based radiopeptides are able to interact with residues Q102, D122, Q126, and N276 by building hydrogen bonds, which are essential binding residues in SSTR2. The molecular docking simulation revealed that the best docking parameter is exhibited by 99mTc/EDDA/HYNIC-cWIWLNA and 99mTc/tricine/HYNIC-cWIWLNA with a binding free energy of –12.59 kcal/mol and –8.96 kcal/mol, respectively. Taken together, nocardiotide-A-based radiopeptides are prospective to be further developed for cancer imaging targeting SSTR2.
The Potency of Camellia Sinensis L. to Reduce Proinflammatory Cytokine Levels in the Acute Respiratory Distress Syndrome Rat Model Wahyu Widowati; Didik Priyandoko; Hanna Sari Widya Kusuma; Rizal Rizal
Journal of Mathematical and Fundamental Sciences Vol. 55 No. 1 (2023)
Publisher : Directorate for Research and Community Services (LPPM) ITB

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.5614/j.math.fund.sci.2023.55.1.6

Abstract

This study was conducted in order to ascertain how green tea extract (GTE) could affect inflammatory markers, including level of interleukin-(IL)-12, IL-18 of serum and lung, tumor necrosis factor (TNF)-α, gene expression of NLR family-pyrin-domain containing 3 (NLRP3) of lung, nuclear factor kappa B (NF-κB), lung histopathology, and IL-6 expression of lung tissue in lipopolysaccharide (LPS)-treated rats as ARDS animal model. Rats were given GTE at dosages of 0, 50, 400, 800 mg/kg of body weight for 28 days to boost their immune systems. The rats were then stimulated with LPS (5 g/kg of BW) and after that continued to receive GTE for 28 days. Levels of serum or lung IL-18, IL-12, TNF-α, were measured using the ELISA method; expression of lung NF-κB and NLRP3 was measured by qRT-PCR; immunohistochemistry (IHC) was implemented to assess lung IL-6 expression; and lung histopathology was evaluated through the bleeding, inflammation, and alveolus scores. GTE had the ability to lower serum IL-18, lung TNF-α, and lung IL-12 levels; suppress the lung gene expression of NF-κB, NLRP-3, IL-6 expression; and improve lung histopathology. Green tea extract inhibited inflammation in the ARDS rat model by decreasing the proinflammatory cytokine level and proinflammatory gene expression.
Bioinformatic Analysis Strategy in Restriction Enzyme Selection for Indonesian Panulirus homarus Identification by PCR-RFLP Indriatmoko Indriatmoko; Adi Pancoro
Journal of Mathematical and Fundamental Sciences Vol. 55 No. 2 (2023)
Publisher : Directorate for Research and Community Services (LPPM) ITB

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.5614/j.math.fund.sci.2023.55.2.4

Abstract

The spiny lobster (Panulirus homarus) is a valuable fishery commodity in Indonesia, particularly in its juvenile life form. However, identifying the early life forms of the spiny lobster can be challenging, as it exhibits similar morphological features compared to the juveniles of other Panilurid lobsters. Molecular-based identification, specifically DNA sequencing, is the best method for species identification, but it requires advanced instruments and is costly. An alternative method is proposed here, using the PCR-RFLP technique, which is low-cost, rapid, and has standard instrumentation requirements. The challenge with this method is selecting the appropriate restriction enzyme to determine the targeted species’ identity. This study proposes using the REfind (https://github.com/indriatmoko07/REfind), R package to select the best restriction enzyme for identifying P. homarus, applicable to other species. The bioinformatics workflow used in this study successfully identified BseSI or BmgI as the most suitable restriction enzymes among 739 restriction enzymes to differentiate P. homarus from other Panilurid species. This result was validated by employing a wet lab test using the BseSI enzyme and successfully validated the bioinformatics result. These findings may be useful for biologists in conducting various studies that require rapid, low-cost, and identification of specific species in the future.

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