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INDONESIA
Berkala Ilmu Kesehatan Kulit dan Kelamin
Published by Universitas Airlangga
ISSN : 19784279     EISSN : 25494082     DOI : 10.20473
Core Subject : Health, Science,
Arjuna Subject : -
Articles 505 Documents
Secondary Syphilis, Anal Condylomata Acuminata, and HIV in Bisexual Male Patient: Another Point of View, Time Evaluation Based on CD4 and Management Vina Ajeng Puspa Dewi; Satiti Retno Pudjiati
Berkala Ilmu Kesehatan Kulit dan Kelamin Vol. 27 No. 2 (2015): BIKKK AGUSTUS 2015
Publisher : Faculty of Medicine, Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (623.775 KB) | DOI: 10.20473/bikk.V27.2.2015.156-162

Abstract

Background: A meta analysis study in China states that male bisexual has higher incidence rate for HIV and syphilis than male-sex-male. Syphilis eases the transmission of HIV, vice versa HIV breaches the integrity of mucosal epithelial barrier, allowing translocation virus and bacterial. Syphilis has higher incidence rates in HIV-infected compare with HIV-uninfected patients. Syphilis influences CD4 of patient. We try discussing a case of secondary syphilis in male bisexual HIV in another point of view, to find which one earlier based on CD4 count. Purpose: to understand another point of view, time evaluation based on CD4 and management in secondary syphilis, anal condyloma accuminata, and HIV in bisexual male patient Case: A 19 years old male bisexual patient complained erythematous rash all over his body, no itch or pain; TPHA 1/2560, VDRL 1/128, positive HIV 3antibody, and CD4 425cell/mm. Case management: HIV onset, considering decrease of CD4 in syphilis or not, are 2-5,8years and 3,08-7,7years, respectively. Therapy was given as single dose benzatin penisilin 2,4billion IU intramuscular. Conclusion:HIV infection occurred before syphilis. No differences in management with HIV-uninfected syphilis patient, more often evaluation interval needed.Key words: syphilis, HIV, bisexual, CD4, onset, management.
Profile of Superficial Mycoses in Pediatric Dermatology Patient Maria Ulfa Sheilaadji; Iskandar Zulkarnain
Berkala Ilmu Kesehatan Kulit dan Kelamin Vol. 28 No. 3 (2016): DESEMBER
Publisher : Faculty of Medicine, Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (391.057 KB) | DOI: 10.20473/bikk.V28.3.2016.223-234

Abstract

Background: Superficial mycoses in children is a fungal infection of the skin, hair and nails that affected children aged 14 years and below. The superficial mycoses common in children are tinea capitis, pityriasis versicolor and diaper candidiasis. Purpose: To evaluate the distribution of superficial mycoses in pediatric patients in Pediatric Dermatology Division of Dermatology and Venereology Outpatient Clinic in Dr. Soetomo General Hospital Surabaya. Methods: Retrospective study using new patient’s medical record during the period of January 1 2013 until December 31 2015. Results: In period year 2013-2015 the total new superficial mycoses’s pediatric patients is 320 with the precentage in 2013 is 0.4%, in 2014 is 0.5%, and in 2015 is 0.4%. The proportion in male is more than female, and most frequent at aged 5-14 that 54.6%. Most common complain is itchy with the most common diagnosed is pitiriasis versicolor 28.3%.  Potasium hydroxide is the most common additional examination in 70.3% and frequent use therapies are ketoconazole and griseofulvin orally. Conclusion: Superficial mycoses especially pitiriasis versicolor in pediatric is still a common issues  in Indonesia, specially in Surabaya.
Bilateral Nevus of Ota Treated with Combination of CO2 Fractional Laser and 1064 nm Nd:YAG Laser Dewi Nurasrifah; Iskandar Zulkarnain
Berkala Ilmu Kesehatan Kulit dan Kelamin Vol. 29 No. 1 (2017): APRIL
Publisher : Faculty of Medicine, Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (404.722 KB) | DOI: 10.20473/bikk.V29.1.2017.81-90

Abstract

Background: Ota’s nevus (nevus fuscocaeruleus ophthalmomaxillaris) was first described by Ota in 1939. It is characterized by blue–black or gray–brown dermal melanocytic pigmentation and typically occurs in areas innervated by the first and second branches of the trigeminal nerve. Mucosal pigmentation may occur involving conjunctiva, sclera, and tympanic membrane (oculodermal melanocytosis), or other sites. Purpose: Describe the clinical manifestation and therapy of bilateral nevus of Ota. Case: A 20-year-old female patient, complaint about dark patches in both of her cheek and forehead since birth. Histopathology has not been done because patient refused to do the biopsy. Diagnosis of bilateral nevus of Ota is made based on anamnesis and clinical manifestations. Discussion: Pasien has undergo Nd:YAG laser session for Ota’s nevus and the result was not satisfactory. Now patient was given combination laser of CO2 fractional laser and 1064 nm Nd:YAG laser for 4 sessions with 3 months interval. After four laser sessions, there has been an improvement in the lesions as the lesions is getting lighter. The purpose of CO2 fractional laser is to increase light delivery into the tissue and for extruding material out of the skin. This laser combination aimed to increase the ability to remove pigment as an alternative method without inducing a systemic allergic reaction. Conclusion: Nevus of Ota is diagnosed based on clinical finding. Combination therapy of CO2 fractional laser and1064 nm Nd:YAG is the mode of choice because of excellent results.
Negative Response of Lymphocyte Transformation Test (LTT) in a Patient Diagnosed as Stevens-Johnson Syndrome: A Case Report Ryski Meilia Novarina; Trisniartami Setyaningrum
Berkala Ilmu Kesehatan Kulit dan Kelamin Vol. 27 No. 2 (2015): BIKKK AGUSTUS 2015
Publisher : Faculty of Medicine, Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (890.252 KB) | DOI: 10.20473/bikk.V27.2.2015.150-155

Abstract

Background: Evidences for the key role of T-lymphocytes in the pathophysiology of Stevens-Johnson syndrome (SJS) may be evaluated by drug patch test (DPT) and lymphocyte transformation test (LTT). Purpose: This LTT technology may reveal the role and function of T-lymphocytes for both diagnostic and research purposes. Case: A 33 year-old woman was admited in Dermatology and Venereology Ward at Dr. Soetomo General Hospital with skin and mucous membrane lesions after taking oral medication. Clinical and laboratory examination were performed, establishing the diagnosis of SJS caused by suspect amoxycillin and paracetamol. Case management: The suspected drug was discontinued immediately. Patient was given appropriate supportive treatment, systemic antibiotic, and intravenous dexamethasone with initial adjusted dose of 0.1-0.2 mg/kg/day daily according to clinical improvement. The DPT and LTT were performed 6 months after the lesions healed completely. Both DPT and LTT revealed negative results. LTT is based on the principle that T-cells proliferate in the presence of a specific-antigen, with sensitivity and specificity of 60-70% and 85%, respectively. The LTT revealed negative response, stimulation index (SI<2). Patients with SJS often show weak positive or even negative LTT response. Conclusions: Negative result of DPT in SJS does not exclude suspected drug. LTT is more objective and specific than DPT, however the clinical severity is not associated with high SI values.
Kadar Hormon 17α-Hydroxyprogesterone (17-Ohp) Serum pada Pasien Pria dengan Akne Vulgaris Sedang-Berat dan Tanpa Akne Vulgaris Ellenita Soebakti; M. Yulianto Listiawan; Evy Ervianti
Berkala Ilmu Kesehatan Kulit dan Kelamin Vol. 30 No. 1 (2018): APRIL
Publisher : Faculty of Medicine, Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (603.631 KB) | DOI: 10.20473/bikk.V30.1.2018.10-17

Abstract

Latar Belakang: Akne vulgaris (AV) adalah penyakit kulit kronis pada unit pilosebaceous. Kelebihan androgen dapat menimbulkan akne dengan cara menginduksi kelenjar sebum. AV pada pria mungkin satu-satunya tanda adanya kelebihan androgen. Tujuan: Mengevaluasi kadar 17-OHP serum pada pasien pria AV sedang-berat dan pria tanpa AV di URJ Kesehatan Kulit dan Kelamin RSUD Dr. Soetomo Surabaya. Metode: Sebuah studi kasus kontrol observasional analitik termasuk 15 kasus AV dan 15 kontrol dari klinik Kulit dan Kelamin rawat jalan rumah sakit Dr.Soetomo, berdasarkan kriteria inklusi dan eksklusi. Hasil: Rerata 17-OHP pada kelompok AV adalah 1.58 ±0,25 ng/mL dan pada kelompok kontrol adalah 0,98 ±0,15 ng/mL. Dengan nilai P adalah P = 0,0001 (P <0,05) Kesimpulan: Kadar serum 17-OHP pada kelompok AV signifikan lebih tinggi dibanding kelompok kontrol. Diperlukan penelitian lebih lanjut untuk menyingkirkan faktor perancu untuk mengetahui lebih peran hormonal dalam patogenesis AV.
Retrospective Study : Rosacea Profile Shakti Indraprasta; Trisniartami Setyaningrum
Berkala Ilmu Kesehatan Kulit dan Kelamin Vol. 27 No. 2 (2015): BIKKK AGUSTUS 2015
Publisher : Faculty of Medicine, Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (119.323 KB) | DOI: 10.20473/bikk.V27.2.2015.114-120

Abstract

Background: Rosacea is a chronic skin disorder which characterized by erythema of the central face that has persisted for months. Primary features of rosacea include flushing, papules, pustules, and telangiectatic. Although rosacea is clearly visible to all, it is largely unknown to misunderstood by the general public. Knowledge relating to the epidemiology, etiology, pathogenesis, and treatment of this facial disorder is limited. Purpose: To evaluate the management of patients with Rosacea in the cosmetic division, dermatovenereology outpatient clinic Dr. Soetomo general hospital period 2010-2012. Methods: Retrospective study of new patients with Rosacea in cosmetic division during 2010-2012. Results: During the period of three years (2010-2012), there were 49 new patients in cosmetic division, dermatovenereology outpatient clinic Dr. Soetomo general hospital. The most common patient was female, with the highest age group of 25-44 years old, and the most clinical feature found were papulopustular rosacea and erythemato-telangiectatic rosacea. The most common treatment were metronidazole for topical treatment and doxycycline for systemic treatment. Conclusions: The most clinical feature were papulopustular and erythematotelangiectatic subtype, only few cases of phymatous subtype, while the ocular subtype was not found. There were so many varieties in the management of rosacea because there was no standard therapy yet for the management of this disease.Key words: rosacea, retrospective study, rosacea subtype.
Increasing of Urinary 8-Hydroxydeoxyguanosine (8-OHdG) Levels in Children with Atopic Dermatitis Shakti Indraprasta; Iskandar Zulkarnain; Evy Ervianti
Berkala Ilmu Kesehatan Kulit dan Kelamin Vol. 28 No. 3 (2016): DESEMBER
Publisher : Faculty of Medicine, Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (155.332 KB) | DOI: 10.20473/bikk.V28.3.2016.186-193

Abstract

Background: Atopic dermatitis (AD) is a chronic inflammation of the skin occurring in individuals with allergic diathesis. Reactive oxygen species (ROS) is assumed to be involved in the pathogenesis of allergic inflammation. 8-Hydroxydeoxyguanosine (8-OHdG) is a marker of oxidative DNA base damage. Previous research showed a various result in urinary 8-OHdG levels of AD in children. Purpose: To evaluate urinary 8-OHdG level of children with AD in Dermatology and Venereology Outpatient Clinic at Dr. Soetomo general hospital Surabaya. Methods: This is a descriptive observational cross sectional research in children with AD at Dermatology and Venereology Outpatient Clinic Dr. Soetomo hospital who qualified inclusion and exclusion criteria in three months period (March to June 2016). Urine sampling for 8-OhdG examination were underwent from all subjets.  Results: Mean urinary 8-OHdG level of children with AD was 17.236 ± 13.596 ng/mL. Mean urinary 8-OHdG level of AD in children with mild, moderate, and severe based on grade of severity were 7.892 ± 5.596 ng/mL, 16.006 ± 13.662 ng/mL, and 27.321 ± 12.668 ng/mL respectively. Conclusion: There is a tendency of increased levels of urinary 8-OHdG in accordance with increasing grade of severity in children with AD which possibly caused by the role of oxidative stress in the pathogenesis of AD. Further research is needed to reveal the role of antioxidant in AD and the connection between the severity of AD and urinary 8-OHdG levels.
The Profile of Erythroderma Patients Shelma Maharani; Trisniartami Setyaningrum
Berkala Ilmu Kesehatan Kulit dan Kelamin Vol. 29 No. 1 (2017): APRIL
Publisher : Faculty of Medicine, Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (174.159 KB) | DOI: 10.20473/bikk.V29.1.2017.44-51

Abstract

Background: Erythroderma is a rare, but it is life threatening. By knowing the profile of eritroderma, can expect the management and the cure of the patient more better. Objective: To evaluate the general profile of erythrodermic patients. Methods: This study was conducted retrospectively in erythrodermic patients in Kemuning Ward dr. Soetomo General Hospital Surabaya in 2011- 2014, collecting data from medical records of patients, including the incidence, etiology, clinical features, investigations, treatment, complications, mortality, and return visit. Results: The incidence of erytroderma patient was 83 (5.3%), gender most was men (54.2%) with the highest age range > 60 years (31.3%), the etiology of most was due to drug reactions (39.7%), skin efflorescence highest number was macular erythematous and thin scale, the percentage of each 69 (83.1%) and 65 (78.3%), the majority results of histopathological examination was drug reaction 23 (43.5%) and psoriasis vulgaris 18 (33.9%), patients were receiving oral dexamethasone therapy (80.7%), mostly complications was on the skin (69.9%), mortality rate was 6.1%. Conclusion: The profile of erythroderma patient has already been described, and the management was giving a good outcome with the mortality rate  6,1%.
Chromomycosis Treatment With Combination Of Itraconazole And Terbinafine Amalia Rositawati; Sunarso Suyoso
Berkala Ilmu Kesehatan Kulit dan Kelamin Vol. 29 No. 2 (2017): AGUSTUS
Publisher : Faculty of Medicine, Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (417.734 KB) | DOI: 10.20473/bikk.V29.2.2017.168-174

Abstract

Introduction: Chromomycosis is a localized chronic mycosis of skin and subcutaneous tissue caused by pigmented fungi. It is most common in tropical regions. Lesion usually presented with trauma history, and characterized by nodular verrucous that grow slowly on the  lower extremities. The disease is difficult to treat. Case Report: A 33-year-old male garderner came with the main complaint multiple bumps accompanied with itchy and pain sensation on left leg that has became wider since 15 years before. There was a history of a thorn trauma in his left lower extrimity and he used to contact with soil and plants. The patient was diagnosed as chromomycosis based on history, clinical features, and confirmed with potassium hydroxide 10% that showed muriform cell, and fungal culture revealed  the species Fonsacaea pedrosoi. The patient has not improved significantly treated with ketoconazole 200 mg 2 times daily for 9 months. The treatment was replaced into itrakonazole 100 mg 2 x 2 tablets combined with terbinafine 250 mg 2 x 1 tablets for 7 months and it gave a good result. Discussion: Predisposing factors in this case were a history of thorn trauma and contact with soil and plants continously. The lesions improved after 7 months treated with itraconazole and terbinafine. Chromomycosis is very difficult to treat and until now the gold standard treatment is not available yet. Combination therapy, itraconazole and terbinafine, could be considered for the therapy of chromomycosis with good result. Combination therapy can be continued until 2-4 weeks after no palpable nodules anymore.
Successful Combination Therapy of Acne Keloidalis Nuchae Kartika Ruchiatan; Erfina Rohana Sormin; Reti Hindritiani; Asmaja Soedarwoto; Hendra Gunawan
Berkala Ilmu Kesehatan Kulit dan Kelamin Vol. 29 No. 3 (2017): DESEMBER
Publisher : Faculty of Medicine, Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (397.999 KB) | DOI: 10.20473/bikk.V29.3.2017.260-263

Abstract

Background: Acne keloidalis nuchae (AKN) is a chronic, inflammatory, idiopathic disorder of hair follicle, characterized by keloidal papules or plaques on the nape and occipital scalp. Various therapies have been reported to treat AKN with various results. Purpose: To observe the efficacy of combination therapy for AKN. Case report: A 19-year-old man presented with multiple pruritic papules, 0.1–0.3 cm in diameter on the nape and occipital area. The histopathological examination revealed neutrophil, eosinophil, and plasma cell infiltration in infundibulum, which was consistent with AKN pathological patterns. Discussion: Combination therapy consisted of 0.025% tretinoin cream, 0.1% mometasone furoate cream, intralesional triamcinolone acetonide 5 mg/ml, and doxycycline 2x100 mg. The improvement was initially observed on 2nd week of follow up, as the lesions had reduced in size and number, and the improvement became more significant on 4th week of follow up. Conclusion: Combination therapy of topical tretinoin, topical and intralesional steroid, and systemic doxycycline shows good result and can be considered in the management of AKN.