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Berkala Ilmu Kesehatan Kulit dan Kelamin

BIKK
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Published by Universitas Airlangga

ISSN : 19784279 EISSN : 25494082 DOI : 10.20473

Core Subject : Health, Science,

Immunology & microbiology Public Health

Arjuna Subject : -

Articles 505 Documents

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Retrospective Study: Candidiasis Vulvovaginalis in Human Immunodeficiency Virus (HIV) and Acquired Immunodeficiency Syndrome (AIDS) Infection Patient Diana Kartika Sari; Dwi MurtiastutikDepartemen
Berkala Ilmu Kesehatan Kulit dan Kelamin Vol. 27 No. 3 (2015): BIKKK DESEMBER 2015
Publisher : Faculty of Medicine, Universitas Airlangga

Background: Candidiasis vulvovaginal is an opportunistic fungal infection. The case of candidiasis vulvovaginalis increases in women with Human immunodeficiency virus (HIV) infection mainly with moderate to severe immunocompromised state. Purpose: To evaluate general feature of candidiasis vulvovaginalis in HIV and acquired immunodeficiency syndrome (AIDS) patient in Outpatient Clinic of Intermediate Care of Infection Disease, Dr. Soetomo General Hospital Surabaya. Methods: Retrospective study of candidiasis vulvovaginalis in HIV and AIDS patients on outpatient UPIPI Instalation Dr. Soetomo General ndthHospital Surabaya during January 2 2009 until Desember 30 2011. Data was taken from medical records. Results: The highest number of new candidiasis vulvovaginalis patient visit was in 2011. Seven patients underwent wet mount and gram examination, all showed positive results. The highest CD4+ examination results are < 200. All patients received ketoconazole treatment. Three patients came back for follow up and having complete healing. Conclusions: Number of candidiasis vulvovaginalis in HIV and AIDS infection cases per year were 5-7 patients. Diagnosis of candidiasis vulvovaginalis was based on patient complaints, physical, and laboratory examinations.Key words: vulvovaginal candidasis, HIV, AIDS.

The Description of Dermoscopy and Wood’s Lamp on Melasma Ryski Meilia Novarina; Rahmadewi Rahmadewi; Hari Sukanto
Berkala Ilmu Kesehatan Kulit dan Kelamin Vol. 29 No. 1 (2017): APRIL
Publisher : Faculty of Medicine, Universitas Airlangga

Background: Melasma is an acquired hypermelanosis disorder occurred symmetrically on the sun exposure area, predominantly on the face and neck. Melasma classification based on Wood’s light examination does not always have positive correlation with the histopathologic examination. Dermoscopy is a new non-invasive modality for examining melasma. Purpose: To evaluate melasma classification based on dermoscopy and Wood’s lamp examination. Methods: This is a descriptive observational cross sectional study, the subjects are melasma patients in Cosmetic Division of Dermatology and Venereology Outpatient Clinic of Dr. Soetomo hospital. This research was conducted for 2 months with a total of 100 samples that had been performed dermoscopy and Wood’s lamp examinations. Results: Conformity melasma examination results in this study obtained three clinical types of melasma, the vast majority were melasma mixture (72 samples). On dermoscopic examination obtained dermal melasma amount of 17 samples (17%) and telangiectasis structure 38%. In addition dermoscopy can also be used to detect ochronosis on the melasma lesions (7 of 100 samples) with the characteristics are arciform curvilinear (worm-like pattern) and teleangiectasis, dot/globuler bluish brown-black, greyish/bluish brown diffuse amorphic structure, and structureless area. Conclusions: Dermoscopic examination revealed more detailed structure and color of melanin deposit in the superficial dermis, teleangiectasis and early detection of ochronosis. Histopathology still the gold standard diagnosis of melasma and ochronosis lesion.

Profile and Evaluation of Dermatophytosis Ardhiah Iswanda Putri; Linda Astari
Berkala Ilmu Kesehatan Kulit dan Kelamin Vol. 29 No. 2 (2017): AGUSTUS
Publisher : Faculty of Medicine, Universitas Airlangga

Background: Dermatophytosis is an infection of the tissues, for example, the stratum corneum of the epidermis, hair, and nails, which is caused by dermatophyte fungi group. This retrospective study has never been done before and the 2011-2013 election was conducted due to changes in the health insurance system at RSUD Dr. Soetomo. Purpose: To evaluated patient management of dermatophytosis in Mycology Division Outpatient Clinic Dr. Soetomo General Hospital 2011-2013. Methods: A descriptive retrospective study the aim to evaluated general description, epidemiology, clinical manifestation, establisment diagnosis, management and repeated control new patient dermatophytosis. Results: Percentage new case dermatophytes infection increased, but the number of visits to URJ for 3 years decreased. The most diagnosis is tinea corporis. Most cases come from Surabaya. The most patient complaints are itching. The most efflorescence is polycyclic. Griseofulvin is the most therapeutic choice given in the case of tinea corporis. Conclusions: In this study most cases of dermatophytosis is tinea korporis. The diagnosis approach of dermatophytosis diagnosis was obtained by anamnesis, physical examination, and additional examination. Most of dermatophytosis treated with antifungal griseofulvin.

Profile of Melasma Patients: A Retrospective Study Alfrid Asditya; Hari Sukanto
Berkala Ilmu Kesehatan Kulit dan Kelamin Vol. 29 No. 3 (2017): DESEMBER
Publisher : Faculty of Medicine, Universitas Airlangga

Background: Melasma is a common hypermelanotic condition that can be frustrating to patients, thus appropriate diagnosis and management of melasma is required. Purpose: To evaluate patient’s profile, diagnosis, and management of melasma. Methods: Retrospective study of new patient in Cosmetic Division, Dermatology and Venereology Outpatient Clinic Dr. Soetomo General Hospital, Surabaya from January 2011 until December 2013. Result: Total new patient of melasma in Cosmetic Division, Dermatology and Venereology Outpatient Clinic, Dr. Soetomo General Hospital, Surabaya from January 2011 until December 2013 (3 years) is 869 patients. Conclusion: Appropriate diagnosis, treatment, and education is needed to manage melasma because of the chronicity and progressivity of this disease.

Perbedaan Kadar Malondialdehid (MDA) pada Pasien Dermatitis Atopik dan Non Dermatitis Atopik Lia Kinasih Ayuningati; Dwi Murtiastutik; Marsoedi Hoetomo
Berkala Ilmu Kesehatan Kulit dan Kelamin Vol. 30 No. 1 (2018): APRIL
Publisher : Faculty of Medicine, Universitas Airlangga

Latar Belakang : Malondialdehid (MDA) adalah senyawa dialdehida yang merupakan produk akhir peroksidasi lipid dalam tubuh, konsentrasi MDA yang tinggi menunjukkan adanya proses oksidasi dalam membran sel. Dermatitis Atopik (DA) adalah penyakit radang kulit yang bersifat kronis dan residif, dengan gejala gatal dapat terjadi pada bayi, anak, dewasa dan biasanya terdapat riwayat asma maupun rhinitis alergi pada diri sendiri atau pada anggota keluarga. Sejumlah penelitian terdahulu menunjukkan MDA telah membantu menjelaskan peranan stres oksidatif pada sejumlah penyakit termasuk pada DA yang berperan dalam proses terjadinya inflamasi. Tujuan: Mengevaluasi status stres oksidatif pada pasien DA di Unit Rawat Jalan (URJ) Kesehatan Kulit dan Kelamin RSUD Dr. Soetomo Surabaya. Metode: Penelitian analitik observasional dengan 50 sampel yang terbagi menjadi dua kelompok dengan jumlah 25 untuk pasien DA dan 25 non DA yang memenuhi kriteria penerimaan dan penolakan. Hasil: Rerata kadar MDA kelompok DA diperoleh nilai 129,14 + 57,31 ng/mL sedangkan pada kelompok non DA diperoleh nilai MDA 73,91 + 32,89 ng/mL. Dari hasil yang ada diketahui bahwa kadar MDA plasma pada pasien DA lebih tinggi bila dibandingkan dengan non DA dan perbedaan ini bermakna signifikan. Simpulan: Kadar MDA pada pasien DA lebih tinggi dibanding non DA. Diperlukan penelitian lebih lanjut menggunakan desain time series untuk mengetahui lebih jauh peran MDA dalam patogenesis DA dan perlu dilakukan penelitian lanjutan yang menunjukkan korelasi peningkatan kadar MDA degan derajat keparahan DA.

Dermoscopic Features of Alopecia Patient Kartika Paramita; M. Yulianto Listiawan; Rahmadewi Rahmadewi
Berkala Ilmu Kesehatan Kulit dan Kelamin Vol. 27 No. 3 (2015): BIKKK DESEMBER 2015
Publisher : Faculty of Medicine, Universitas Airlangga

Backgroud: Alopecia is hair loss of the scalp that occurs in mostly men and about 30% of women during their lifetime. Prevalence of alopecia is increased along with age in both men and women. Using of dermoscope can help the diagnostic accuracy and avoid scalp biopsy for diagnosis. Purpose: Identifying dermoscope examination results and determine the pathophysiology of dermoscope features. Methods: Cross sectional and descriptiove observational study to all of alopecia patients who fulfilled the inclusion criteria at outpatient clinic Dr. Soetomo General Hospital Surabaya in December 2014 through February 2015 performed dermoscope examination Result: There were 20 patients who fulfilled the inclusion criteria, consisted of 3 patients with androgenetic alopecia, 8 alopecia areata, 4 tinea capitis, 2 discoid lupus erythematosus, 1 psoriasis vulgaris, 1 seborheic dermatitis, and 1 trichotilomania. Conclusion: Most of all dermoscope features accordance with the description in the literature, the most diagnosis is androgenetic alopecia.Key words: alopecia, dermoscope, zig-zag hair, black dots.

Bacterial Vaginosis Abdul Karim; Jusuf Barakbah
Berkala Ilmu Kesehatan Kulit dan Kelamin Vol. 28 No. 3 (2016): DESEMBER
Publisher : Faculty of Medicine, Universitas Airlangga

Background: Bacterial vaginosis (BV) is the most common cause of vaginal discharge symptoms in reproductive women. BV is the most common cause of malodor of vaginal discharge and fluor albus, but 50% of BV patients give no symptoms. Purpose: To evaluate the general overview and management of new BV patients at the Sexual Transmitted Infection Division of Dermatology and Venereology Outpatient Clinic Dr. Soetomo General Hospital Surabaya from the period of 2012-2014. Methods: A retrospective study was perfomed by evaluating medical records of new BV patients including basic data, history taking, examination, diagnosis, treatment, follow up, and counseling. Results: The overall number of new cases is 33. The majority age range 25-44 years old (57.6%) and 84.8% are married. The most main complaint is vaginal discharge without subjective complaints (42.4%), the most common type of complaint is recurrent ( 54.5%), the most sexual partners is husband (60.6%), usage history of vaginal douching (30.3%), the most vaginal discharge appearance is serous (75.8%), Whiff test positive and pH > 4.5 only 9.1% respectively. All microscopic preparation showed clue cell (100%). Therapy with metronidazole is given in 81.8%. Conclusion: The general overview of BV cases showed a small incidence with sexually active age group being the majority of cases and with the main complaint is vaginal discharge without other subjective complaint. The right management is needed to improve good service and reduce the recurrence rate.

Effect of Lactobacillus plantarum on Total Immunoglobulin E Serum and Scoring Atopic Dermatitis (SCORAD) Index in Children With Atopic Dermatitis Renata Prameswari; Linda Astari; Afif Nurul Hidayati; Cita Rosita Sigit Prakoeswa
Berkala Ilmu Kesehatan Kulit dan Kelamin Vol. 29 No. 2 (2017): AGUSTUS
Publisher : Faculty of Medicine, Universitas Airlangga

Background: The prevalence of atopic dermatitis (AD) has been increased for several decades. T-helper cell (Th)1 and Th2 disregulation influence the level of immunoglobulin (Ig)E and interfere Scoring Atopic Dermatitis (SCORAD) index. Management approachment only relieved the symptoms, therapy with probiotic are potentially improve this disregulation. Lactobacillus plantarum (LP) has been fullfilled as probiotic criteria and it’s safely used in human. Methods: In a randomized, double-blind, placebo-controlled trial, twenty (22) patients were randomized to take LP or placebo for 12 weeks with 2 weeks wash-out period in Pediatric Division, Dermatology and Venereology Outpatient Clinic. Total IgE serum level and SCORING indeks were evaluted before and after intervention. Results: Twelve (12) patients in probiotic group and 10 patient in placebo group completed the study. Our findings revealed that there is no significant different in total IgE serum between LP (504.533 IU/ml ± 415.686 IU/ml) and placebo (909.580 ± 885.051 IU/ml) respectively (p=0.117). Mean decreased difference of SCORAD index in LP group (36.784 ± 8.705) significant greater than placebo (26.860 ± 5.021) respectively (p= 0.000). Conclusion: Total IgE serum in both group not significantly different. However, SCORAD indeks in LP group showed a significantly greater reduction. LP is beneficial in the treatment of children with AD.

Anti-inflammatory Activity of Ointment in Water Soluble Base of Volatile Oil of Syzygium aromaticum with Variation Composition of Oleic acid and Propylene glycol as Enhancer Dewi Rahmawati; Nining Sugihartini; Tedjo Yuwono
Berkala Ilmu Kesehatan Kulit dan Kelamin Vol. 29 No. 3 (2017): DESEMBER
Publisher : Faculty of Medicine, Universitas Airlangga

Background: The dosage form of ointment clove essential oil in water-soluble base has proven efficacious as anti-inflammatory with eugenol as active substance. Further research to increase the penetration of eugenol in penetrating the skin layer needs to be done with the addition of enhancer. Purpose: To determine the anti-inflammatory activity of ointment base water soluble of clove essential oil with composition variation of oleic acid and propylene glycol as enhancers. Methods: The ointment was made using fusion method. Addition of enhancer composition refers to the system Simplex Lattice Design for Formula 1, Formula 2 and Formula 3 successively used: 100% oleic acid; 50% oleic acid: 50% propylene glycol; and 100% propylene glycol. The evaluation of anti-inflammatory activity was based on the parameters epidermal thickness, the number of inflammatory cells, and the number of cells that expressed cyclooxygenase-2 (COX-2). The anti-inflammatory tests used male mice strain BALB/C which was induced by croton oil. Results: The enhancer composition of oleic acid and propylene glycol affect the activity of ointment clove essential oil in water-soluble base. Conclusion: The increasing composition of propylene glycol improved anti-inflammatory activity of ointment.

Kelainan Sistemik dan Laboratorik pada Pasien Kusta dengan Reaksi Tipe 2/ ENL di Divisi Kusta Unit Rawat Jalan dan Instalasi Rawat Inap SMF Kesehatan Kulit dan Kelamin RSUD Dr. Soetomo Surabaya Periode 2011-2013 Febrina Dewi Pratiwi; Indropo Agusni
Berkala Ilmu Kesehatan Kulit dan Kelamin Vol. 30 No. 1 (2018): APRIL
Publisher : Faculty of Medicine, Universitas Airlangga

Latar Belakang: Erythema Nodosum Leprosum (ENL) pada pasien kusta perlu mendapat perhatian khusus oleh karena seringkali membuat pasien meragukan keberhasilan terapi kusta. Tujuan: Mengevaluasi gambaran umum kelainan sistemik dan laboratorik pada pasien kusta dengan reaksi tipe 2/ENL. Metode: Penelitian retrospektif terhadap pasien kusta dengan reakti tipe2/ENL di Divisi Kusta Unit Rawat Jalan (URJ) dan Instalasi Rawat Inap (IRNA) Kulit dan Kelamin RSUD Dr. Soetomo Surabaya tahun 2011-2013. Hasil: Dalam kurun waktu 2011-2013 didapatkan jumlah kunjungan pasien baru sebanyak 434 pasien, 106 diantaranya mengalami ENL. Sebagian besar pasien kusta dengan ENL berjenis kelamin laki-laki (69,8%), usia terbanyak antara 30-44 tahun (51,9%), 65% berasal dari kota Surabaya. LL (Lepromatous Leprosy) adalah tipe kusta terbanyak (62,3%). Keluhan sistemik tersering adalah demam (84,9%), mialgia dialami 57,5% pasien, mual muntah terjadi pada 47,2% pasien. Sebagian besar mengalami anemia (49,0% pasien laki-laki dan 16,9% pasien perempuan), 50,9% mengalami leukositosis, 42,5% dengan trombositosis, 53,8% dengan hipoalbuminemia. Simpulan: Sebagian besar pasien kusta dengan reaksi tipe2/ENL mengalami kelainan sistemik dan laboratorik.

Page 15 of 51 | Total Record : 505

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