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Berkala Ilmu Kesehatan Kulit dan Kelamin

BIKK
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Published by Universitas Airlangga

ISSN : 19784279 EISSN : 25494082 DOI : 10.20473

Core Subject : Health, Science,

Immunology & microbiology Public Health

Arjuna Subject : -

Articles 481 Documents

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Profil Pasien Kusta Baru pada Anak Wulan, I G.A. Kencana; Agusni, Indropo; Rosita, Cita
Berkala Ilmu Kesehatan Kulit dan Kelamin Vol 26, No 2 (2014): BIKKK AGUSTUS 2014
Publisher : Faculty Of Medicine Airlangga University

Latar belakang: Kusta hingga saat ini masih menjadi masalah kesehatan di Indonesia. Kusta pada anak merupakan indeks epidemiologis untuk menentukan transmisi penyakit serta sebagai salah satu indikator dalam keberhasilan program pemberantasan penyakit kusta nasional. Tujuan: Mengevaluasi profil pasien kusta pada anak. Metode: Penelitian retrospektif terhadap semua kasus kusta baru pada anak (0-14 tahun) yang datang ke Unit Rawat Jalan (URJ) Kesehatan Kulit dan Kelamin RSUD Dr.Soetomo Surabaya mulai Januari 2009 sampai Desember 2011. Hasil: Didapatkan 37 pasien anak (5,5%) dari 677 kasus kusta baru. Kasus paling banyak (70,3%) terdapat pada kelompok usia 10-14 tahun. Laki-laki lebih banyak daripada perempuan. Berdasarkan klasifikasi WHO, sebanyak 29 kasus (78,4%) adalah kusta multibasiler (MB) dan 8 kasus (21,6%) adalah kusta pausibasiler (PB). Tipe terbanyak adalah kusta tipe BB (59,5%) pada kelompok MB dan diikuti tipe TT (16,2%) pada kelompok PB. Seluruh kasus mendapat pengobatan Multidrug Therapy (MDT) sesuai panduan WHO. Kontak serumah didapatkan 68,7% kasus. Simpulan: Ditemukan 37 kasus kusta baru pada anak di RSUD Dr. Soetomo Surabaya selama tiga tahun, terutama pada kelompok umur 10-14 tahun, dengan kasus terbanyak berupa kusta MB tipe BB. Kontak serumah masih memegang peranan yang penting pada transmisi kusta.Kata kunci: kusta, anak-anak, retrospektif.

Serum Level Of Dehydroepiandrosterone Sulphate Hormone at Various Acne Vulgaris Severity Miryana, Windy; Cholis, Mohammad; Rofiq, Aunur; Sugiman, Tantari
Berkala Ilmu Kesehatan Kulit dan Kelamin Vol 26, No 3 (2014): BIKKK DESEMBER 2014
Publisher : Faculty Of Medicine Airlangga University

Background: The pathogenesis of acne vulgaris (AV) is multifactorial. Hormone dehydroepiandrosterone sulfate (DHEAS) is an androgen hormone important in the initial formation of AV in women, namely the development and differentiation of sebaceous glands, which are mostly found in human blood serum. Research looking at differences in hormone levels in serum DHEAS between various degrees of severity of AV in women has not been done. Purpose: To measure whether there was a difference of serum level of DHEAS hormone at various AV severity in women. Methods: The study design was a cross-sectional analytic observational, with ninety subjects, women, by using inclusion and exclusion criterias. The diagnosis was based on clinical examination. AV severity was categorized into 3 groups, mild, moderate, and severe, that based on Combined Acne Severity Index by Lehmann. Serum level of DHEAS hormone was measured with ELISA method. The difference of serum level of DHEAS hormone at various AV severity was analyzed with non-parametric statistical test Kruskal-Wallis and Mann-Whitney. Results: The mean serum level of DHEAS hormone in women with mild AV is 1076.01Â±257.89 pg/ml, in moderate AV is 1971.95Â±272.73 pg/ml, and in severe AV is 19678.22Â±33536.38 pg/ml. Conclusion: There were significant difference of serum level of DHEAS hormone between women with mild and moderate AV, mild and severe AV, and moderate and severe AV (p value < 0.05), but still below from normal level.Key words: acne vulgaris, women, observasional analytic, serum level DHEAS, severity grading.

Oral Corticosteroid Therapy in Leprosys new patients with Type 2 Reaction Listiyawati, Irma Tarida; Sawitri, Sawitri; Agusni, Indropo; Prakoeswa, Cita Rosita Sigit
Berkala Ilmu Kesehatan Kulit dan Kelamin Vol 27, No 1 (2015): BIKKK APRIL 2015
Publisher : Faculty Of Medicine Airlangga University

Background: Leprosy type 2 reactions is an acute inflammatory episode in lepromatous leprosy patient that ascociated with deposition of immune complexes. Standard regiment for severe reaction is corticosteroid. Almost Leprosy type 2 reactions patients become chronic and recurrent so it implicates to more complications if it was not managed well. Purpose: To determine the distribution of type 2 reactions patients which treated with oral corticosteroid in leprosy division of dermatovenereology outpatient clinic of Dr. Soetomo General Hospital. Methods: Retrospective study using new patients medical record during the period of January 1 2009 until December 31 2013 and the observation continued until December 31 2013. Results: The total type 2 reactions patients with oral corticosteroid was 112 patients, mostly were male aged between 25-64 years and has the Lepromatous Leprosy (LL) type (33%), the reactions happened after RFTÂ (43.8%), 65.2% had metil prednisolon medication, the initial equivalent dose was 30 mg in 32.1% patient. 21.4% patient had more than one cycleÂ of corticosteroid therapy and 8.9% patient had the steroid side effect. Conclusion: Leprosys type 2 reactions tend to be chronic and recurrent and the impact were patients got longterm continuously corticosteroid medication, so the patients need to be monitored including side effects.Key words: leprosys type 2 reaction, oral corticosteroid, side effects.

Salivary Cortisol Levels Representing Serum Cortisol Levels in Atopic Dermatitis Patients Adisty, Novia Indriyani; Hutomo, Marsudi; Indramaya, Diah Mira
Berkala Ilmu Kesehatan Kulit dan Kelamin Vol 27, No 3 (2015): BIKKK DESEMBER 2015
Publisher : Faculty Of Medicine Airlangga University

Background: Atopic dermatitis (AD) is a chronic inflammatory skin disorder, recurrent lesion with a distinctive and specific distribution of lesions according phases. Patients with allergic diseases have been known to have a variety of patterns of cortisol. Dysfunction of the hypothalamic-pituitary-adrenal (HPA) axis and the role of cortisol has been studied in patients with DA. Free cortisol adrenal cortex is considered biologically active, which passively diffuses into all body fluids including saliva. Another advantage is the saliva examination is non-invasive, stress free and easy to do anywhere. Purpose: To analyze the correlation between levels of serum cortisol and salivary cortisol in patients with AD. Methods: Analytical, observational, cross-sectional study of the 29 AD patients who underwent blood and saliva samples by the method of "passive drooling" conducted on the hour 8:00 to 9:00 to see the levels of serum cortisol and salivary cortisol. Results: Twenty-nine subjects revealed mean serum cortisol levels 6,703,82g/dL, mean salivary cortisol levels was 1,430,96g/dL. Equation of salivary cortisol = 0,471+0,142*serum cortisol 2 (R=28,5%). Conclusions: The increasing of serum cortisol level of AD patients will result in increased levels of cortisol in saliva. Saliva collection methods by âpassive droolingâ were able to describe the serum cortisol levels at 28,5%.Key words: atopic dermatitis, serum cortisol, salivary cortisol.

Perbedaan Dermatitis Seboroik dan Psoriasis Vulgaris Berdasarkan Manifestasi Klinis dan Histopatologi Astindari, Astindari; Sawitri, Sawitri; Sandhika, Willy
Berkala Ilmu Kesehatan Kulit dan Kelamin Vol 26, No 1 (2014): BIKKK APRIL 2014
Publisher : Faculty Of Medicine Airlangga University

Latar belakang: Dermatitis seboroik (DS) dan psoriasis sering sulit dibedakan baik secara klinis maupun secara histopatologi. Anamnesis yang tepat dengan memperhatikan usia, riwayat keluarga, dan pemeriksaan klinis yang teliti serta ditunjang dengan pemeriksaan histopatologi, dapat menentukan diagnosis yang tepat. Tujuan: Mengevaluasi perbedaan DS dan psoriasis supaya klinisi dan patolog bisa membuat diagnosis yang benar.Telaah kepustakaan: Secara epidemiologi, terdapat berbagai perbedaan antara DS dan psoriasis. Hal itu bisa dilihat dari usia saat timbulnya lesi, jenis kelamin, ras, maupun genetik. Lokasi lesi dan manifestasi klinis juga mempunyai ciri yang berbeda. Biopsi kulit dibutuhkan untuk membantu menegakkan diagnosis yang tepat.Gambaran histopatologi DS bervariasi sesuai dengan perjalanan penyakitnya: akut, sub-akut, dan kronis, sedangkan psoriasis mempunyai ciri khas berupa pemanjangan rete ridges, abses Munro atau adanya abses Kojog. Simpulan: Terdapat beberapa perbedaan antara DS dan psoriasis dari usia pertama kali muncul lesi, lokasi lesi, manifestasi klinis dan gambaran histopatologi.Kata kunci: dermatitis seboroik, psoriasis, manifestasi klinis, gambaran histopatologi.

Oral Hairy Leukoplakia in Patient with HIV/AIDS Agustina Tri Pujiastuti; Dwi Murtiastutik
Berkala Ilmu Kesehatan Kulit dan Kelamin Vol. 28 No. 1 (2016): APRIL
Publisher : Faculty of Medicine, Universitas Airlangga

Background: Oral hairy leukoplakia (OHL) is an asymptomatic white plaque with vertical corrugations most commonly found on the lateral borders of the tongue. It is caused by local infection of Epstein- Barr Virus (EBV). OHL is usually associated with immunocompromised condition, and mainly described in patients with human immunodeficiency virus (HIV). Purpose: to report a case of oral hairy leukoplakia in an HIV patient that is often misdiagnosed as oral candidasis. Case: A 44-years old female came to the Dermato-Venereology Outpatient Clinic of Dr. Soetomo General Hospital Surabaya with complaint of persistent asymptomatic whitish color on both borders of her tongue. History taking revealed that at first the whitish color appeared spreading on the tongue, but after taking antifungal treatment, only the lesion on the borders still persisted, all attempts to scrub off the lesion failed. There were also history of diarrhea, fever and cough for almost 1 month. Further examination of HIV antibody 3 method tests revealed reactive result with CD4+ count of 1 cel/uL. Physical examination revealed bilateral painless white well demarcated plaque with “hairy” like corrugated appearance on the lateral borders of the tongue. Discussion: From history, clinical findings, and the reactive HIV antibody examination, the patient was diagnosed with AIDS with oral hairy leukoplakia. The patient was treated with acyclovir 200 mg, 5 times daily. After 2 weeks of treatment, clearance was achieved. Conclusion: The establishment of OHL which oftenly mistaken as oral candidiasis has a diagnostic value for HIV infection. Systemic antiviral institution and antiretroviral (ARV) medications as prevention for recurrence gave satisfying result. Key words: oral hairy leukoplakia, HIV, acyclovir.

Relationship between Diet and Acne Kristina Sihaloho; Diah Mira Indramaya
Berkala Ilmu Kesehatan Kulit dan Kelamin Vol. 28 No. 2 (2016): AGUSTUS
Publisher : Faculty of Medicine, Universitas Airlangga

Background: Acne is a disorder of pilosebasea unit, that mostly affect an adolesecent, caused by hormonal changing. Dietary is one factor that was thought to induce acne. But the association between diet and acne are still controversial. Purpose: Review the role of some diets for acne Review: Acne is multifactorial disease, whereas diet is one of many factors that excarcerbate acne. Some dietaries are thought have some roles in acne, including carbohidrate, milk, chocolate, fatty acid, zinc-iodine, vitamin A, and antioxidant. Some research has proved the relationship between diets and acne but there are still few limitations. Conclusion: Relationship between diets and acne still need more research with better methods. Key words: acne, diet, glicemic index.

Retrospective Study: Glycolic Acid Peel in Photoaging Patient Brama Rachmantyo; Diah Mira Indramaya
Berkala Ilmu Kesehatan Kulit dan Kelamin Vol. 28 No. 1 (2016): APRIL
Publisher : Faculty of Medicine, Universitas Airlangga

Background: Photoaging is premature skin aging that is caused by sun exposure in long periode. Glycolic acid peel is one of photoaging treatment that improve skin at epidermal layer. Improper patient selection and irregular follow-up may become factors of unsuccessful treatment. Purpose: To evaluate gycolic acid peel treatment for photoaging for improvement of medical service in the future. Methods: A retrospective study to photoaging patiens that were managed with glicolyc acid peel in Medical Cosmeutic Division Dermatology and Venereology Departement Dr. Soetomo General Hospital Surabaya on period from January 2011 to December 2013. The data were collected from medical record, Results: New patient of photoaging is 455 patients in Medical Cosmetic Division, 15.8% patients were treated with glycolic acid peel. Diagnosis classification were using Glogau classification. Thirty six point one percent of patient did not undergo follow up and 47.1% of patient’s interval of follow up were more than 4 weeks. Majority of patient (37.5%) have no improvement. Conclusion: Education to photoaging patient that undergo glycolic acid peel need to be improved. Clinical worsening and no improvement in some patients may be caused by irregular follow up. Key words: photoaging, retrospective study, glycolic acid peel.

A Retrospective Study: Incidence and Management of Genodermatoses Dwi Ratna Adisty; Iskandar Zulkarnain
Berkala Ilmu Kesehatan Kulit dan Kelamin Vol. 28 No. 2 (2016): AGUSTUS
Publisher : Faculty of Medicine, Universitas Airlangga

Background: Genodermatoses are rare congenital diseases of the skin especially genetically determined. Genodermatoses can be grouped into three categories: chromosomal, single gene, and multifactorial. Skin condition in the genodermatoses patients not only important to start the right therapy but also to detect the other system diorders including malignancy. Objective: To evaluate the incidence of genodermatoses and to know the management of each patients. Methods: A retrospective study of genodermatoses patients in Kemuning Ward Dr. Soetomo Hospital Surabaya in 5 years period 2010-2014. Results: The incidence of genodermatoses among patients in Kemuning Ward was 10 of 1912 (0.52%).They are five males and five females (1:1). This study had shown that the diagnosis of genodermatoses were ichthyosis in 3 patients, epidermolysis bullosa (EB), and xeroderma pigmentosum (XP) each in 2 patients, neurofibromatosis (NF) type 1 in 1 patient, lymphangioma circumscriptum in 1 patient, and verrucous epidermal nevi in 1 patient. Positive family history of the same disease was obtained in one patients with xeroderma pigmentosum. No data of consanguinity found in ten patients. Conclusion: Small number of patients with genodermatoses due to the small incidence of the disease. The management vary depends on the clinical manifestations observed in each patient. Key words: genodermatoses, incidence, management, retrospective.

Retrospective Study: Diagnosis and Management of Vulvovaginalis Candidiasis Ditta Harnindya; Indropo Agusni
Berkala Ilmu Kesehatan Kulit dan Kelamin Vol. 28 No. 1 (2016): APRIL
Publisher : Faculty of Medicine, Universitas Airlangga

Background: Vulvovaginalis candidiasis (VVC) is an infection of the vaginal mucosa and or vulva caused by Candida species. As many as 70-75% of women are infected by CVV at least once during their lifetime, which most often occurs in women of childbearing age. Purpose: To evaluate the general overview of new VVC patients at the Sexual Transmitted Infection Division Dermato-Venereology Outpatient Clinic Dr. Soetomo General Hospital Surabaya from the period of 2010-2012. Methods: This is a retrospective study, and evaluating medical records of new CVV patients including basic information, history taking, physical and laboratory examination, management, follow up, and counseling. Result: There were 325 new CVV patients (11.5%) from the total 2.813 patients from the total of new patients at the STI Division Dermato-Venereology Outpatient Dr. Soetomo General Hospital Surabaya, range of age was mostly 25-44 years old (53.2%) and 257 (79.1%) patients were married. The most main complaint was vaginal discharge accompanied with itchy sensation in 213 (65.5%) patients. The most vaginal discharge appearance was white like cottage cheese in 245 (75.3%) patients. From the wet mount 220 (67.7%) patients showed either blastospore or pseudohyphae, while from the gram stain 220 (67.7%) patients showed 217 (66.8%) patients showed either blastospore or pseudohyphae. Therapy with ketoconasol is in 239 (73.2%) patients. Conclusion: Appropriate diagnosis, adequate therapy, also risk factors exploration and counseling are very important in the management of VVC.Key words: Vulvovaginalis candidiasis, fluor albus, itch, pseudohyphae, ketoconazole.

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