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MEDISAINS
Published by Universitas Muhammadiyah Purwokerto
ISSN : 16937309     EISSN : 26212366     DOI : -
Core Subject : Health,
Medicine & Pharmacology Nursing Public Health
MEDISAINS: Jurnal Ilmiah Ilmu-ilmu kesehatan merupakan sarana penyebarluasan ilmu pengetahuan, riset, teknologi dan inovasi dibidang kesehatan yang diterbitkan tiga kali dalam setahun (April, Agustus dan Desember). Jurnal Medisains adalah jurnal peer reviewed dan Open-Access yang dikelola oleh Fakultas Ilmu Kesehatan Universitas Muhammadiyah Purwokerto dan di terbitkan dibawah Lembaga Publikasi Ilmiah dan Penerbitan (LPIP) Universitas Muhammadiyah Purwokerto.
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Articles 7 Documents
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Search results for , issue "Vol 20, No 1 (2022)" : 7 Documents clear
Models of antenatal classes for pregnant mothers Sriatmi, Ayun; Suwitri, Sri; Shaluhiyah, Zahroh; Nugraheni, Sri Achadi
MEDISAINS Vol 20, No 1 (2022)
Publisher : Universitas Muhammadiyah Purwokerto

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30595/medisains.v20i1.12820

Abstract

Introduction: Although it has proven to be helpful, the attendance of pregnant mothers in Antenatal Classes (AC) was still low, so an ineffective breakthrough application of AC was needed according to the mother's wishes and interests.Objective: The study aimed to compare various models of practical AC for pregnant mothers to improve behavior prevention of high-risk pregnancies.Method: This study is quasi-experimental with a nonequivalent control group and pre-posttest design. The population of all pregnant mothers in Semarang City, with 181 samples, was divided into three groups (Extended, Virtual and Conventional). Measurements were carried out four times to see the mean score increasing, and the results of the last measurement were analyzed using the One Way ANOVA test to compare the effectiveness of these three groups.Results: There was an increase in the mean value of all dimensions of the behavior of high-risk prevention based on its measurement stages. The extended model has the highest improvement, followed by the Virtual model. Statistically, there was a better chance in all behavioral dimensions after the intervention. There were differences in all dimensions of maternal behavior between the extended and the conventional model. In contrast, only knowledge and practice differed in the virtual model but not in attitudes, beliefs, and intentions.Conclusion: Extended and virtual models of AC effectively improved high-risk prevention behaviors better than conventional models. Although the increase was not as high as the extended model, the virtual model has an excellent opportunity to be developed as a strategy to overcome time constraints for mothers and health providers.
Frailty among hemodialysis patients Adi, Ginanjar Sasmito; Utomo, Eri Purba
MEDISAINS Vol 20, No 1 (2022)
Publisher : Universitas Muhammadiyah Purwokerto

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30595/medisains.v20i1.12374

Abstract

Introduction: Hemodialysis patients have physical vulnerability due to the progressive decline of the body's systems. The physical changes in the patients can lead to haemostatics failure, known as frailty syndrome. The frail condition can cause maladaptive psychological responses due to changes that can cause anxiety in patients.Objective: This study aims to determine the prevalence of frailty in hemodialysis patients and to find out the different factor that correlates in frailty patients undergoing hemodialysis therapy.Method: This is a cross-sectional study involving 55 respondents who underwent hemodialysis therapy at the Jember Klinik Hospital. The instruments used in this study were the Edmonton Frail Scale (EFS) and the Hamilton Anxiety Rating Scale. Results: Moderate frailty was found in 23 patients (41.8%), followed by mild frailty in 18 patients (32.7%) and severe frailty in 14 patients (25.5%). In terms of anxiety, 18 patients (32.7%) had severe anxiety, 20 had moderate anxiety (36.4%), 12 (21.8%) had mild anxiety, and the other 7 (12.7%) were not anxious. The statistical analysis shows a significant difference in the average level of anxiety and the frailty status (p<0.001) among the patients. Conclusion: Frailty was highly prevalent in hemodialysis patients and had relations with anxiety and different sociodemographic characteristics of patients. The assessment of frailty should be considered when clinicians intervene and prevent worsening in patients.
Development of an electronic measuring device for body weight and nutritional status for children under two years old Nasution, Naimah; Widyawati, Melyana Nurul; Ramlan, Djamaluddin
MEDISAINS Vol 20, No 1 (2022)
Publisher : Universitas Muhammadiyah Purwokerto

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30595/medisains.v20i1.13143

Abstract

Background: Measurement of body weight and nutritional status in children under two years are still used manuals. Besides that, there is no tool to measure nutritional status, so it is necessary to develop a tool to make it easier.Purpose: The study aims to develop and test a measuring device for weight and nutritional status in children under two years.Methods: This study is Research and Development (R&D). It consisted of 5 stages, stage I (literature study), stage II (product development), stage III (expert validity and phase I trials), stage IV (product revision and final product), and stage V (phase II trials).Result: The electronic measuring device for weight and nutritional status has been created. The result is that the tool effectively determines the weight and nutritional status. The average value of tool testing is below 5%, which means the calibration value of the tool's sensitivity is valid in determining body weight. In addition, it can also determine nutritional status with a p=0,65, which means that there is no difference between measuring nutritional status using the tool and manually.Conclusion: The electronic measuring device effectively determines the weight and nutritional status.
In vivo study of cardioprotective effect of bay leaf (Syzygium polyanthum) extract Ikhtiari, Refi; Sari, Laura Kartika; Nasution, Ali Napiah; Ginting, Chrismis Novalinda; Handoko, Erwin; Lister, I Nyoman Ehrich
MEDISAINS Vol 20, No 1 (2022)
Publisher : Universitas Muhammadiyah Purwokerto

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30595/medisains.v20i1.12502

Abstract

Background: The excessive use of chemotherapy drugs such as doxorubicin might induce cardiovascular diseases. Heart-specific biomarker enzymes such as LDH and BNP indicated the early signs of cardiotoxicity. However, there is no report on the effect of bay leaf on LDH and BNP nor its bioactive compounds and histopathology analysis.Objective: This study aims to determine the cardioprotective effect of Ethanol Extract of Bay Leaf (EEBL) based on phytochemical analysis, LDH and BNP levels, and cardiac histology of rats administered with doxorubicin.Methods: About 24 Wistar rats were divided into six groups treated with 100 mg/kg BW, 300 mg/kg BW, and 500 mg/kg BW of EEBL with CMC-Na 0.5 %, vitamin E, and doxorubicin. Preconditioning was 14 days, followed by 21 days of intraperitoneal administration. LDH and BNP parameters were measured on days 1st, 7th, 14th, and 20th. Histology analysis was conducted on day 21st.Results: Dark green EEBL showed sufficient physical quality and properties for practical application in pharmacy. EEBL has significantly affected LDH, BNP, and cardio recovery dose-dependent. The most effective doses were observed at 500 mg/kg BW, and its performance is not statistically different from those of the commercial vitamin E. The histopathological images revealed significant improvements in interstitial edema, wavy fibers, hemorrhage, intracellular vacuole, and inflammatory cell infiltration. Here we report six bioactive compounds obtained from EEBL have cardioprotective effects; Neophytadiene, squalane, phytol, methyl palmitate, stigmasterol, and  9,12-Octadecanoic acid methyl ester.Conclusion: This study has shown the promising potential of bay leaf extract as a cardioprotector with sufficient quality pharmacological standards.
Calcium supplementation from chicken eggshells to increase nitric oxide levels and control blood pressure in gestational hypertension Rahmah, Aulia Agyanti; Hadisaputro, Suharyo; Ambarwati, Eny Retna
MEDISAINS Vol 20, No 1 (2022)
Publisher : Universitas Muhammadiyah Purwokerto

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30595/medisains.v20i1.13378

Abstract

Background: Hypertension is one of the highest causes of death in pregnant women. Calcium deficiency can lead to hypertension. Chicken eggshell can be used as a natural calcium supplementation therapy in hypertension.Purpose: Analyze the effect of chicken eggshell on blood pressure through the increased nitric oxide level in gestational hypertension.Methods: This is Quasy experiment research with pretest and posttest with control group design. Respondents were ≥20 weeks pregnant women with gestational hypertension. Determination of respondents by purposive sampling obtained experimental group (n=12) and control group (n=12). 1.1 g/day of eggshell flour was given for 14 days.Result: Mean of systolic and diastolic blood pressure in experimental group decreased 14.25 mmHg or 9.5% (p=0.000) and 12.84 mmHg or 13.04% (p=0.000) after received chicken eggshell flour for 14 days compared to control group mean of systolic and diastolic blood pressure increased 1.92 mmHg or 1.35% (p=0.000) and 0.33 mmHg or 0,34% (p=0.121). Nitrit oxide level of experimental group increased 8.250 μmol/L or 20.93% (p=0.020) and control group decreased 3.083 μmol/L or 7.20% (p=0.488).Conclusion: Chicken eggshell flour affects increasing nitric oxide levels and controls systolic and diastolic blood pressure in gestational hypertension.
From global to local action: rise from the pandemic, an efforts to increase routine immunization coverage Purwito, Dedy
MEDISAINS Vol 20, No 1 (2022)
Publisher : Universitas Muhammadiyah Purwokerto

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30595/medisains.v20i1.13586

Abstract

Since the first vaccine was developed (1796; smallpox vaccine), the world has seen its impact on health and well-being. Vaccines are one of the most influential scientific innovations of all time, helping to protect generations of people from infectious diseases throughout their lives. Parents need not worry too much about their children suffering from a deadly disease that has plagued previous generations because of vaccines. However, a top-down approach is needed so that vaccination becomes necessary for every people worldwide.
Cookies for hypertension patients Herawati, Nurul; Kumorowulan, Suryati; Djamil, Masrifan
MEDISAINS Vol 20, No 1 (2022)
Publisher : Universitas Muhammadiyah Purwokerto

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30595/medisains.v20i1.12880

Abstract

Background: Papaya and celery leaves are usually consumed as cooked vegetables and have a bitter taste and distinctive aroma. The flavonoid antioxidants in papaya and celery can increase the dilation of blood vessels, thereby possibly lowering blood pressure. They have been made to make cookies easy to enjoy and liked by hypertensive patients.Objective: Making and testing papaya combined celery leaf cookies to control blood pressure in hypertensive patients.Methods: This is a true experimental pretest-posttest with a control group design. The respondents are 34 women of reproductive age who have hypertension, divided into 17 respondents in the treatment group and 17 respondents in the control group. The cookies are made from papaya and celery leaves, and 5 mg of Amlodipine are given every day (for two weeks). Furthermore, blood pressures are measured on days 1, 5, 10, and 15.Results: Hypertension patients consuming papaya combined celery leaf cookies and amlodipine 5 mg had lower blood pressure than those consuming only 5 mg amlodipine (p<0.05).Conclusion: Papaya leaf cookies with a combination of celery are suitable for consumption by hypertensive patients because they can lower blood pressure.

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