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INDONESIA
Journal of Agromedicine and Medical Sciences
Published by Universitas Jember
ISSN : 24609048     EISSN : 27145654     DOI : -
Core Subject : Health,
Health Professions
Jurnal Agromedicine and Medical Sciences (AMS) adalah jurnal berkala empat bulan (Februari, Juni dan Oktober) yang berisi berbagai artikel dalam bentuk penelitian, tinjauan sistematis dan laporan kasus dalam bidang kedokteran dengan fokus pada ilmu-ilmu kedokteran dasar, kedokteran klinis dan agromedis.
Arjuna Subject : -
Articles 305 Documents
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Identification of Intestinal Protozoa in Adults in Pasie Nan Tigo Sub-Distric Koto Tangah Padang Genia Alda Fitria; Nuzulia Irawati; Firdawati Firdawati
Journal of Agromedicine and Medical Sciences Vol 8 No 3 (2022)
Publisher : Faculty of Medicine, University of Jember

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19184/ams.v8i3.29697

Abstract

Intestinal protozoan infection is one of the leading causes of morbidity and mortality worldwide. However, it is difficult to estimate the true problem of protozoal infections because cases are under-reported. This study aimed to identify intestinal protozoa in healthy adults. This study used a categorical descriptive research design and used a multistage random sampling technique. This research was conducted in Pasie Nan Tigo, Koto Tangah, Padang from July 2020 to December 2021 with a total of 61 samples obtained. Furthermore, the samples were examined using the direct stool examination method and with modified Ziehl-Neelsen staining. The results of this study were obtained, from 61 subjects the most age group was 45-49 years (27.9%), the most gender was female (88.5%), and the incidence of intestinal protozoal infection was 3.3% where only Blastocystis hominis found. The vacuole stage and cyst stage were found to be 50%, respectively. All samples examined were single infection. The conclusion of this study is that Blastocystis hominis infection is still found in healthy adults in Pasie Nan Tigo, Koto Tangah, Padang. Therefore, supportive therapy and measures to prevent infection transmission need to be carried out so that the incidence and morbidity rates can be reduced. Keywords: Intestinal protozoa infections, healthy adult
Low Oxygen Tension Inhibits Senescence in Bone Marrow Mesenchymal Stem Cells (BMSCs) Candra Bumi
Journal of Agromedicine and Medical Sciences Vol 8 No 3 (2022)
Publisher : Faculty of Medicine, University of Jember

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19184/ams.v8i3.33843

Abstract

Background: Stem cells have been used in regenerative medicine but are so few in the body that they require cell culture. Stem cell culture was performed under normal oxygen tension and passage was carried out until the number of cells was sufficient for therapy. Stem cell cultures under normal oxygen tension do not match the stem cell microenvironment, which can lead to premature senescence. This study aims to determine the association of low oxygen tension with premature senescence of mesenchymal stem cells (MSCs) through inhibition of p21 expression by HIF-1a. Methode: The research method used rabbit bone marrow in New Zealand as a source of MSCs. The results of isolation of MSCs were divided into two groups for cultured on normal and low oxygen tension until 10 passages. Cells were identified using flowcytometry for cd105 and cd34. At early and late passage, the expression of p21 and HIF-1a was examined using immunofluorescence while senescence was examined using β-galactosidase assay. Results: The results showed that in low oxygen cultures HIF-1a expression increased significantly (p <0.05) while p21 expression decreased significantly (p <0.05) as did the β-galactosidase assay. Conclusions: The conclusion of this research is low oxygen tension culture able to decrease premature senescence culture of invitro stem cells mesenchymal through obstacles p21 by HIF-1a. Keywords: p21 expression, HIF-1a expression, late passage, premature senescence.
Pericardial Effusion as A Clue to The Diagnosis of Systemic Lupus Erythematosus Zhafirah Ramadhanty; Teuku Rahadiyan
Journal of Agromedicine and Medical Sciences Vol 9 No 1 (2023)
Publisher : Faculty of Medicine, University of Jember

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19184/ams.v9i1.36500

Abstract

Pericardial effusion (PE) is accumulation of fluid in the pericardial sac. There are broad etiologies of PE, such as inflammation, infection, and malignancy. The etiology must be discovered because the treatment will be focused based on the cause. We present a 40-year-old female who came to the cardiology clinic with exertional dyspnea as the only symptom. The patient had a history of unspecific joint pain two months prior. Physical examination, chest x-ray, and electrocardiography revealed no specific findings. However, on echocardiography, we found moderate circumferential pericardial effusion. The patient then admitted for further evaluation. Blood counts, peripheral blood smear, urinalysis, and immunoserology examination such as ANA and anti-dsDNA was ordered and the result led to the diagnosis of systemic lupus erythematosus (SLE). High dose steroid injection was given for five days and the symptoms disappeared. Follow-up echocardiography after a week of hospital admission revealed significant reduction of pericardial fluid.
Anti-Inflammatory Activity of Stem Barks Ethanol Extracts of Asam Kandis On Male White Rats Hanafis Sastra Winata; Muhammad Andry; Muhammad Amin Nasution; Firman Rezaldi; Ade Shindy F Br Sembiring
Journal of Agromedicine and Medical Sciences Vol 9 No 1 (2023)
Publisher : Faculty of Medicine, University of Jember

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19184/ams.v9i1.37478

Abstract

Inflammation is a complex series of changes in tissue due to tissue injury caused by bacteria, trauma, chemicals, heat, and pain. Gamboge (Garcinia xanthochymus) is a fruit-bearing tree native to Southeast Asia. Plants of the genus garcinia are rich in secondary metabolites such as flavonoids, steroids, and triterpenes which have potential pharmacological activity. This study aimed to determine the anti-inflammatory activity based on the reduction in edema volume of Gamboge (Garcinia xanthochymus) stem bark. The inquiry was experimental. Through maceration, an ethanol extract of the gamboge stem was created. The animals were divided into five groups, each containing five white male rats. The test given was a suspension of gamboge ethanol extract at doses of 200, 400, and 600 mg/kgBW, a negative control of 1% Na CMC suspension, and a positive control of 2.25 mg/kgBW sodium diclofenac. Observations were made for 6 hours, and then data were analyzed using a two-way analysis of variance (ANOVA) test. The results showed that gamboge ethanolic extract was proven to have an anti-inflammatory effect in white male rats induced by carrageenan starting at doses of 200, 400, and 600 mg/kgBW, marked by a significant difference to the negative control (p<0.05). The 600mg/kgBW dose group showed no significantly different results from the positive control group (p>.05). These results concluded that the dose group 600mg/kgBW was the best dose of gamboge stem ethanol extract had an anti-inflammatory activity based on reducing the volume of leg edema of white male rats. Keywords: Asam Kandis Stem Bark; Anti-Inflammation; Male White Rats
Cover AMS Vol. 9 No. 1 (2023) Zahrah Febianti
Journal of Agromedicine and Medical Sciences Vol 9 No 1 (2023)
Publisher : Faculty of Medicine, University of Jember

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

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Analysis of Health Literacy Index Difference Amongst Generation in Jagapura Primary Healthcare Work Area Maitsa' Fatharani; Nafiys Hilmy
Journal of Agromedicine and Medical Sciences Vol 9 No 1 (2023)
Publisher : Faculty of Medicine, University of Jember

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19184/ams.v9i1.33929

Abstract

Health literacy is one of the factors which has a big contribution to a person's health status. The rapidity of technology growth eases access to health information, this situation has to be balanced with good health literacy index. Several factors as generation, occupation, and education influence health literacy index. Many measuring tools have been developed to assess the health literacy index. Researcher uses the latest health literacy survey questionnaire in Indonesia, namely HLS-EU-SQ10-IDN which contains 10 questions. This type of research is analytic observational. The research was conducted in the work area of ​​the Jagapura Primary Health Care, Gegesik District, Cirebon Regency, West Java. A total of 146 people that spread over five village is taken as samples with purposive sampling method. The results of Chi Square analysis is the association between generation and health literacy index showed insignificant results with p = 0.705. For the correlation with work, the results are also insignificant with p = 0.296. Meanwhile, education level is associated significantly with p = 0.018. The data obtained indicate that there is no significant correlation between generational differences and the health literacy index. Older generation with higher educational background tends to have better health literacy index. On the other hand, the researcher concludes that government need a strategy to increase the quantity and quality of education in Indonesia as an endeavour to increase health literacy index in our society. Keywords: health literacy index, generation, education, occupation
The Correlation of Coping Strategies and Burnout Syndrome among Health Workers in Regional Hospital Dr. Soebandi Jember Devi Octavia Kartika Sari; Ancah C N Marchianti; Inke Kusumastuti
Journal of Agromedicine and Medical Sciences Vol 9 No 1 (2023)
Publisher : Faculty of Medicine, University of Jember

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19184/ams.v9i1.30484

Abstract

The Covid-19 pandemic significantly impacts the mental health of health workers, including leading to the occurrence of burnout syndrome. Health workers in Dr. Soebandi Regional Hospital, as a regional referral hospital for Covid-19, were potentially exposed to the risk of experiencing burnout syndrome. Effective coping strategies might alleviate burnout syndrome symptoms. Therefore, this study was conducted to analyze the correlation of coping strategies and burnout syndrome level among health workers at Dr. Soebandi Regional Hospital. This cross-sectional study conducted from November to December 2021 included 88 physicians and nurses of Dr. Soebandi Regional Hospital. Data were collected using the Brief Cope Inventory and the Maslach Burnout Inventory Questionnaires. The SPSS spearman rho analysis showed a weak significant positive correlation of maladaptive coping strategies and burnout syndrome level (r=0.263; p=0.0013). The self-blame coping strategy had a weak significant positive correlation with burnout syndrome level (r=0.267; p=0.0012). We recommend to develop programs to protect health workers from becoming secondary victims of various adverse events and counseling provision to doctors and nurses regarding appropriate coping strategies for stress management at work. Keywords: Burnout Syndrome; coping strategy; RSD Dr. Soebandi; Mental Health.
Prediction of Coronary Heart Disease on Civil Servants in Jember by Framingham Risk Score Muhammad Nadzir A. Akbar; Suryono Suryono; Aris Prasetyo; Ricky Roosdiana Dewi
Journal of Agromedicine and Medical Sciences Vol 9 No 1 (2023)
Publisher : Faculty of Medicine, University of Jember

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19184/ams.v9i1.30205

Abstract

Coronary heart disease is one of the biggest causes of death in developing countries. Civil servants (PNS) are a group of people who are susceptible to the disease because of their busy lives. Framingham risk score (FRS) can predict the occurrence of coronary heart disease in the next 10 years. The purpose of this study was to determine the prediction of coronary heart disease for the next 10 years in civil servants in Jember Regency. This type of research is descriptive observational with a cross sectional design. The data was taken from the medical records of patients with echelon II and III civil servants who did a medical sheck up at Dr. Soebandi Hospital in December 2013. Prediction of coronary heart disease for the next 10 years using the FRS method. From 63 medical record data, the prediction results of coronary heart disease in civil servants were 76.2% low risk, 17.5% moderate risk, and 6.3% high risk. Keywords: coronary heart disease, civil servants, framingham risk score
Water PH Correlates With The Number of Mosquito Larvae in Nature Tourism Park Mentari Permana Putri; Gita Dwi Prasasty; Chairil Anwar; Dwi Handayani; Dalilah Dalilah
Journal of Agromedicine and Medical Sciences Vol 9 No 1 (2023)
Publisher : Faculty of Medicine, University of Jember

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19184/ams.v9i1.37116

Abstract

Mosquitoes go through four development phases: egg, larva, pupa and adult. The growth, survival, and adaptation of mosquito larvae are strongly influenced by the physical and chemical characteristics of the waters. Nature tourism parks have ecological and environmental potential for the development and spread of mosquitoes and vector diseases. This study aims to look at the correlation of the physical and chemical elements of water to the number of mosquito larvae. The study design was cross-sectional analytic observational. In TWA, 57 containers were found with 10 indoor and 47 outdoor locations. The container contains water with a salinity of 0-0.3, pH 4.5-8.3, TDS 3-899 ppm, and a temperature of 26 - 34℃. A total of 423 mosquito larvae consisting of Culex and Aedes species. Ae. albopictus is the dominant larval species found. Based on the Spearman test, there was no significant correlation between temperature, total dissolved solids and salinity with the number of mosquito larvae (p>0.05), while PH was positively correlated with the number of mosquito larvae (p = 0.019). Keywords: Chemical, Physical, Water, Mosquito larva
Immunization Stress-Related Response (ISSR) from Covid-19 Vaccination First-Dose among Medical Clerkship Students in dr. Soebandi Hospital Jember Supangat Supangat; Elly Nurus Sakinah; Achmad Ilham Tohari; Muhammad Rijal Fahrudin Hidayat; Muhammad Yuda Nugraha; Tegar Syaiful Qodar; Bagus Wahyu Mulyono
Journal of Agromedicine and Medical Sciences Vol 9 No 1 (2023)
Publisher : Faculty of Medicine, University of Jember

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19184/ams.v9i1.26673

Abstract

Vaccination is one of the recommended way to eradicate Covid-19 pandemic. Unfortunately, there are still many people who refuse to get vaccinated. One of the causes is anxiety about the side effects that occur after vaccination. With this misinformation about vaccines, public anxiety is getting higher, so that more and more people are hesitant to get vaccinated. The purpose of this study was to determine the level of anxiety related to vaccines in medical students who have more knowledge about vaccines than the general public society. The anxiety assessment method used was the Hamilton Rating Scale for Anxiety (HARS) questionnaire. There were 108 medical clerkship students in this study, consisting of 25 male respondents and 83 female respondents, aged between 21-27 years. Based on the HARS-score obtained, it showed that all respondents were in the low or minimal anxiety range. Aspects of anxiety predominately appeared in the pre-vaccination phase. The differences between men and women were influenced by hormonal fluctuations and conditions before vaccination, such as stress, workload, knowledge capacity, and information obtained related to vaccination. Keywords: Anxiety, Covid-19, HARS-score, ISRR, Vaccines

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