cover
Contact Name
-
Contact Email
-
Phone
-
Journal Mail Official
-
Editorial Address
-
Location
Kab. bantul,
Daerah istimewa yogyakarta
INDONESIA
Mutiara Medika: Jurnal Kedokteran dan Kesehatan
ISSN : 14118033     EISSN : 26140101     DOI : 10.18196/mm
Core Subject : Health,
Jurnal Mutiara Medika Fakultas Kedokteran dan Ilmu Kesehatan (MMJKK) Universitas Muhammadiyah Yogyakarta is a peer-reviewed and open access journal that focuses on promoting medical sciences generated from basic sciences, clinical, and community or public health research to integrate researches in all aspects of human health.
Arjuna Subject : -
Articles 934 Documents
Structured Physical Activity can Increase High-Density Lipoprotein Cholesterol Levels Dharaindas, Hanna Kumari
Mutiara Medika: Jurnal Kedokteran dan Kesehatan Vol 20, No 1 (2020): January
Publisher : Universitas Muhammadiyah Yogyakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18196/mm.200134

Abstract

High levels of low-density lipoprotein (LDL) cholesterol and low levels of high-density lipoprotein (HDL) are risk factors for coronary heart disease (CHD). Early research has proven that physically active people have higher HDL levels, and it is obtained by doing regular physical exercise in both men and women. One of the exercises that have an anti-CHD effect is an aerobic exercise. This study aims to identify the effect of structured physical activity on increasing HDL cholesterol. This research is pre-experimental research with one group pretest-posttest design. Interventions given were aerobic exercise conducted at least 150 minutes per week and monitored for three months. The population and sample were members of the R and K gymnastics studio in Central Jakarta, who were 18-60 years old. Samples were selected using the purposive sampling method. Data was collected by taking the respondent's blood serum and the HDL cholesterol levels examined by enzymatic methods in the laboratory, while the data analysis used paired t-test statistical tests. The results showed an increase in HDL cholesterol levels in 18 out of 25 respondents with the results of the paired t-test p=0.001. The conclution is structured physical activity has significant effect on increasing HDL cholesterol levels among gymnastics members.
Luka pada Leher Akibat Senjata Tajam pada Kasus Bunuh Diri Widagdo, Hendro
Mutiara Medika: Jurnal Kedokteran dan Kesehatan Vol 6, No 1 (2006)
Publisher : Universitas Muhammadiyah Yogyakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18196/mmjkk.v6i1.1892

Abstract

A young female corpse was found with several wounds on her neck. Judging from what was observed at the scene, the death was suicide. Medically, the truth of the suicide was attested to by the fact that there were no signs of the victim s defensive act, a deep incised wound wasfound on her leftside neck andparallel to it there were two slight wounds. Psychical pressure was suspected occurred on the victim.Dilaporkan seorang wanita yang meninggal dunia dengan luka-luka di leher di sebuah rumah yang dalam keadaan kosong. Pemeriksaan di TKP menunjukkan tanda-tanda dari suatu kasus bunuh diri. Pemeriksaan di Instalasi Kedokteran Forensik RSUP Sardjito terhadap jenazah ditemukan perlukaan pada bagian kiri leher yang terdiri dari satu luka iris utama yang fatal dan dua buah luka iris dangkal yang dikenal sebagai luka-luka iris percobaan, semuanya dengan arah yang sejajar dengan arah luka iris utama. Tidak ditemukan tanda-tanda kekerasan pada bagian tubuh yang lain. Korban meninggal akibat luka iris utama pada bagian kiri leher sehingga memutuskan pembuluh darah karotis kiri yang menyebabkan teijadinya perdarahan. Diduga korban mengalami depresi.
Pengaruh Pemberian Ekstrak Kayu Siwak (Salvadore persica) 50% Dengan Frekuensi Yang Berbeda Terhadap Ketahanan Email Gigi Rattus norvegicus Dewanti H, Gilang; Triawan, Andi
Mutiara Medika: Jurnal Kedokteran dan Kesehatan Vol 8, No 2 (s) (2008): Juli
Publisher : Universitas Muhammadiyah Yogyakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18196/mmjkk.v8i2 (s).9402

Abstract

Miswak (Salvadora Persica) have antibacterial substances which can reduce the amount of bacteria in mouth so the tooth become healthy and prevent incidence of holey tooth. Intention of this research is to analyze usage of 5 0% miswak extract with different frequencies (1 x one day, 3 days once and once a week) to acid resistance of Rattus norvegicus tooth enamel.Research subject use I5 Rattus norvegicus at the age of 20 old days. The treatment is given 50% miswak extract topically on the incisivus tooth of Rattus norvegicus lower jaw with different frequencies. Each group (consist of 5 Rattus norvegicus) divided based on the frequencies that giving. The frequencies are I x one day, once every 3 day and once every a week. Treatment conducted during 30 day. After Rattus norvegicus in the age of 51 days, incisivus tooth of Rattus norvegicus taken away from lower jaw. After that phosphoric acid gel 37% applied above entire/all surface of tooth. We roentgen the tooth with digitally periapical Roentgen and calculated the damage on the enamel with score.Research result indicate that the given of 5 0% miswak extract with frequency I x one day, once every 3 days and once a week have significant difference (p=0,024) to acid resistance of Rattus norvegicus tooth enamel. Giving of 5 0% miswak extract with frequency I x is one day compared to with frequency once every 3 days also have difference which significant (p=0,042). While comparison between the giving of 50% miswak extract with frequency I x one day and once a week also have significant difference (p=0,020).Conclusions of research, the giving of miswak extract 5 0% with different frequency have different influence significantly to acid resistance of Rattus norvegicus tooth enamel. Miswak is a natural substance that can use for keep our mouth health. 
Prevalensi Seropositif IgM/IgG Toksoplasma pada Wanita Pranikah dan Tinjauan Faktor Risiko Kepemilikan Kucing Sari, Bernadeta Renny Yulianti; Gugun, Adang Muhammad
Mutiara Medika: Jurnal Kedokteran dan Kesehatan Vol 14, No 1 (2014): January
Publisher : Universitas Muhammadiyah Yogyakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18196/mmjkk.v14i1.2379

Abstract

Toksoplasmosis merupakan suatu penyakit infeksi parasit yang dapat dijumpai hampir di seluruh dunia karena berbagai faktor seperti usia, kebiasaan, gizi, kontak dengan kucing dan konsumsi daging kurang matang. Wanita pranikah memiliki risiko terinfeksi toksoplasma yang berdampak pada kelainan selama kehamilan, kecacatan atau kematian janin. Toksoplasma yang terdeteksi sebelum kehamilan bisa segera diobati sehingga mencegah penularan ke fetus. Penelitian ini bertujuan untuk mengetahui prevalensi seropositif IgM/IgG Toksoplasma pada populasi wanita pranikah dan hubungan kepemilikan kucing dengan prevalensi seropositif IgM/IgG Toksoplasma. Penelitian ini merupakan penelitian obser- vasional analitik dengan pendekatan cross sectional. Subyek penelitian ini adalah wanita pranikah di Kabupaten Bantul berjumlah 90 orang. Data diambil dari hasil kuesioner dilanjutkan pengambilan sampel serum untuk pemeriksaan IgM/IgG anti toksoplasma dengan ELISA. Data dianalisis dengan Fisher test. Hasil menunjukkan 55,6% seropositif Toksoplasma. Ditinjau dari faktor risiko, dari 11 orang berisiko positif memelihara kucing, dan 7 (63,6%) diantaranya seropositif Toksoplasma. Hasil uji Fisher test menun¬jukkan nilai exact test 0,405 (0,05) dan CI: 0,716-1,909. Disimpulkan bahwa tidak ada hubungan anta¬ra faktor risiko kepemilikan kucing dengan seropositif IgM/IgG Toksoplasma pada wanita pranikah di Bantul. Toxoplasmosis is a parasitic infection disease that can be found almost all over the world with various factors such as age, habits, nutrition, contact with cats and consumption of undercooked meat. Premarital women have a risk of infection with Toxoplasma that affects the abnormalities during preg¬nancy, disability or death of the fetus. Toxoplasma infection that detected before pregnancy can be treated immediately to prevent transmission to the fetus. This study aims to know the relation between the prevalence of seropositive IgM/IgG Toxoplasma among premarital female population and the rela¬tion between having cats and prevalence of IgM/IgG seropositive toxoplasma. This research is an ana¬lytic observational with the cross sectional approach. Subjects are premarital women that living in Bantul regency amounted 90 sample. The data is taken from questionnaire and serum examined by ELISA to check the IgM/IgG anti Toxoplasma. The data analyzed by Fisher test. The result showed there are 55,6% seropositive IgM/IgG toxoplasma The evaluation of contact with cats risk factor show that 63,6% of 11 respondence are positive having cats. contact with cat risk factor, from 11 women that have positive risk factor, 7 of them have toxoplasma Seropositive (63,6%). Data analysis using Fisher test, show that exact test value 0,405 (0,05) and CI: 0,716-1,909. It is concluded that no correlation between contact with cat risk factor with the IgM/IgG Seropositive of Toxoplasma on premarital women in Bantul.
Perbandingan Pemberian Ekstrak Kayu Siwak (Salvadora persica) 50% Dan Larutan Sodium Fluorida 2% Terhadap Ketahanan Dentin Gigi Rattus norvegicus Ekanila, Maryanur; Triawan, Andi
Mutiara Medika: Jurnal Kedokteran dan Kesehatan Vol 7, No 2 (s) (2007): Juli
Publisher : Universitas Muhammadiyah Yogyakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18196/mmjkk.v7i2 (s).9429

Abstract

Siwak memiliki banyak kegtmaan bagi kesehatan gigi dan mulut, diantaranya menghilangkan stain, memutihkan gigi, mengurangi plak dan gingivitis juga sebagai antitumor, efek bakteriosidal dan menstimulasi pertahanan gingiva, membantu kerusakan jaringan, serta menghambat pembentukan karang gigi. Sedangkan sodium fluorida terdapat khusus pada tulang dan khususnya di email dan dentin gigi dan digunakan untuk mencegah karies gigi, menghambat dekalsifikasi, menstimulasi remineralis asi serta menghambat pembentukan asam oleh kuman mulut.Penelitian ini bertujuan untuk menganalisis perbandingan antara penggunaan ekstrak kayu siwak 50% dan larutan sodium fluorida 2% terhadap ketahanan asam dentin gigi Rattus norvegicus. Penelitian dilakukan secara eksperimental laboratoris secara in vitro dan menggunakan 10 Rattus norvegicus. Perlakuan yang diberikan adalah pembeiian ekstrak kayu siwak secara topikal pada gigi rahang bawah 5 Rattus norvegicus dan pemberian larutan sodium fluorida secara topikal pada gigi rahang bawah 5 Rattus norvegicus. Pemberian ekstrak kayu siwak 5 0% dan larutan sodium fluoiida 2% dilakukan sejak Rattus norvegicus berumur 20 hari sampai Rattus norvegicus berumur 50 hari. Kemudian gigi Rattus norvegicus dietsa dengan gel asam fosfat 37% selama 60 detik lalu dirontgen digital periapikal dan di skor untuk mendapatkan data masing-masing vatiabel selanjutnya dilakukan uji statistik Mann- Whitney Test.Hasil uji statistik dengan Mann- Whitney Test didapat (p=0,221) karena (p0,05) maka eksnak kayu siwak 50% mempunyai pengaruh yang tidak signifikan terhadap ketahanan dentin gigi Rattus norvegicus dibandingkan dengan larutan sodium fluorida 2%.Hasil penelitian menunjukkan bahwa ekstrak kayu siwak 50% dan larutan sodium Fluorida 2% memiliki pengaruh yang tidak berbeda secara signifikan terhadap ketahahan dentin gigi Rattus norvegicus.
The Level of SGOT and SGPT after Consuming Putri Malu (Mimosa pudica, Linn) Leaves Boiled on Carbon Tetrachloride (CCl4) Induced Rats (Rattus norvegicus) Bulan, Marina Sari; Pramono, Ardi
Mutiara Medika: Jurnal Kedokteran dan Kesehatan Vol 9, No 2 (s) (2009)
Publisher : Universitas Muhammadiyah Yogyakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18196/mmjkk.v9i2 (s).1609

Abstract

The activity testing of flavonoid compounds as antioxidant and as scavenger of free radical, from the putri malu (Mimosa pudica, Linn) leaves had been performed for prevention liver damage This study used unrandomized control trial method. Ten male Wistar rats with 150¬250 gr of body weight were divided into two groups. Measuring of SGOT and SGPT before treating was taken to determine first level of SGOT and SGPT. Group I as a control group was given with 1 ml aquadest orally for 9 days. Group II as a experiment group was treated 1, 890 gr for each rat/day putri malu (Mimosa pudica, Linn) leaves boiled for 9 days. In the day 10th, both of groups were induced 1 ml/of kg body weight carbon tetrachloride (CCl4) intraperitoneally. Twenty four hours after CCl-induced, measuring of serum SGOT and SGPT was done. The result showed Statistic test of independent t - test indicated that there was significant difference beetwen control group and experiment group. Grade of rate SGOT and SGPT after treatment of group control more than hight with p0.001 (p0.05) so it could be concluded that putri malu (Mimosa pudica, Linn) leaves boiled can be prevent liver damage greated carbon tetrachloride (CCl4) induced.Telah dilakukan uji aktivitas hepatoprotektif penangkal radikal bebas terhadap flavonoid dari daun Putri malu (MimosaPudica, Linn.) pada tikus putih galur wistar (Rattus norvegicus) jantan induksi CCl4. Penelitian ini bertujuan mengetahui kemampuan rebusan daun putri malu (Mimosa pudica, Linn) sebagai hepatoprotektor dan menurunkan efek radikal bebas akibat perlakuan hepatotoksin CCl4. Penelitian ini menggunakan metode unrandomized control trial. Sepuluh ekor tikus putih galur wistar (Rattusnorvegicus) jantan dengan berat badan 150-250 gram dibagi menjadi dua kelompok. Pengukuran kadar SGOT dan SGPT sebelum perlakuan dilakuan untuk mengetahui kadar SGOT dan SGPT awal. Kelompok pertama sebagai kelompok control diberikan 1 ml aquades secara oral selama 9 hari. Kelompok kedua sebagai kelompok uji diberi rebusan daun putri malu (Mimosapudica, Linn) sebanyak 1,890 mg/ekor/hari selama 9 hari. Pada hari ke-10 kedua kelompok diinduksi 1 ml/kgBB CCl4 secara intraperitoneal. Dua puluh empat jam setelah induksi CCl4 dilakukan pengukuran kadar SGOT dan SGPT pada kedua kelompok. Hasil uji statistik independent t- test menunjukkan terdapat perbedaan yang signifikan antara kelompok control dan kelompok uji. Kadar rata-rata SGOT dan SGPT setelah perlakuan pada kelompok kontrol lebih tinggi dari pada kelompok uji dengan nilai p0,01 (p0,05) sehingga dapat disimpulkan rebusan daun putri malu (Mimosapudica, Linn) dapat mencegah kerusakan hepar akibat induksi karbon tetraklorida.
Pengaruh Pemberian Seduhan Teh Kelopak Bunga Hibiscus sabdariffa L. terhadap Kadar Kolesterol Total Perokok Aktif Utami, Inta Resty; Orbayinah, Salmah
Mutiara Medika: Jurnal Kedokteran dan Kesehatan Vol 13, No 3 (2013)
Publisher : Universitas Muhammadiyah Yogyakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18196/mmjkk.v13i3.2481

Abstract

Rokok mengandung radikal bebas yang dapat menyebabkan terjadinya peroksidasi lipid. Hal tersebut menyebabkan kadar kolesterol total plasma meningkat. Seduhan teh kelopak bunga Rosella (Hibiscus sabdariffa L.) diketahui memiliki efek antioksidan yang dapat meredam aksi radikal bebas. Penelitian ini bertujuan untuk mengetahui kadar kolesterol total setelah pemberian seduhan teh kelopak bunga H. sabdariffa L. Penelitian bersifat quasi experimental dengan rancangan penelitian pre and post test controlled group design. Subjek berjumlah 27 orang, perokok aktif 14 orang kelompok perlakuan dan 13 orang kelompok plasebo. Perlakuan berupa pemberian seduhan teh kelopak bunga rosella (H. sabdarifa L.) dengan dosis 3 gram kelopak bunga kering 1x sehari. Kelompok plasebo diberi sirup rendah kalori. Masing-masing perlakuan selama 21 hari. Subjek diambil darahnya sebelum perlakuan sebagai data pre test. Setelah perlakuan 21 hari, subjek kembali diambil darahnya untuk data post test. Hasil penelitian ini menunjukkan adanya penurunan kadar kolesterol total pada perokok aktif setelah pemberian seduhan teh kelopak bunga H. sabdariffa L. sebesar 4,58 mg/dl dengan nilai p=0,002 ( 0,05) sedangkan pada kelompok plasebo juga terjadi penurunan kadar kolesterol total sebesar 3,21 mg/ dl dengan nilai p=0,006 ( 0,05). Tidak ada perbedaan antara kedua kelompok tersebut dengan nilai p sebesar 0,281 ( 0,05). Disimpulkan bahwa seduhan teh kelopak bunga Rosella (Hibiscus sabdariffa L.) dapat menurunkan kadar kolesterol total pada perokok aktif.Cigarretes contain free radicals which can cause lipid peroksidation to happen. it cause increasing of total plasma cholesterol, steeping of roselle’s calyx have antioxydant effect which can block free radicals activity. This study aims to determine total cholesterol levels after given of tea steeping calyces H. sabdariffa L. This is quasi experimental research with pre and post test controlled group design. The amount of subject that used is 14 as roselle group at the same dose (3 grams of dried calyx) and 13 as placebo group who receive low calories syrup for 21 days. The subject will be taken their blood before receive any inter­vention as a pre test data. After 21 days of intervention the subject taken their blood again as a post test data. Result shows that there is lowering of total cholesterol level in active smokers after administering of steeping of roselle’s calyx in the amount of 4,58 mg/dl with p=0,002 (0,05). While at the placebo group there is also lowering of total cholesterol level as big as in the amount of 3,21 mg/dl with p=0,006 (0,05). So that there is no differences between both groups with p=0,281 (0,05). It is concluded that the steeping of roselle’s calyx can lowering total cholesterol level in active smoker.
Hubungan Kadar Ekskresi Yodium Urin Ibu Menyusui dengan Perkembangan Bayi Usia Bawah 2 Tahun di Daerah Endemik GAKY Saputra, Rizky Hermawan; Noor, Zulkhah
Mutiara Medika: Jurnal Kedokteran dan Kesehatan Vol 15, No 2 (2015): July
Publisher : Universitas Muhammadiyah Yogyakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18196/mmjkk.v15i2.3759

Abstract

Gangguan akibat kekurangan yodium (GAKY) pada bayi berdampak menghambat proses tumbuh kembang. Penelitian ini bertujuan untuk mengetahui hubungan kadar ekskresi yodium urin (EYU) ibu menyusui dengan perkembangan bayi usia dibawah dua tahun di daerah endemik GAKY. Penelitian ini bersifat observational dengan desain cross sectional. Sampel penelitian adalah 30 ibu menyusui yang memiliki bayi berusia dibawah dua tahun. Kadar EYU diukur dengan menggunakan Ammonium Persulfat Dry Digestion dan Perkembangan bayi dinilai dengan menggunakan Kuesioner Pra Skrining Perkembangan (KPSP). Kadar median EYU ibu kemudian dikorelasikan dengan status perkembangan bayi, menggunakan uji Spearman. Hasil menunjukkan bahwa kadar EYU ibu optimal (173,5 ppm). Sebanyak sembilan ibu (30%) memiliki status EYU optimal, namun status perkembangan bayi dengan kategori meragukan sebanyak 12 bayi (40%). Hasil uji korelasi antara kadar EYU ibu dengan status perkembangan bayi menunjukkan p = 0,428; r = 0,150. Disimpulkan bahwa tidak terdapat hubungan yang bermakna antara kadar EYU ibu menyusui dengan status perkembangan bayi usia dibawah dua tahun.Disorders due to iodine deficiency (GAKY) in infants have an effect inhibit the growth and development processes. This study aims to determine the relationship of urinary iodine excretion (UIE) of breastfeeding mothers with the development of infants aged under two years in the endemic areas of GAKY. This research is observational with cross sectional design. The sample was 30 breastfeeding mothers with babies under two years old. Urinary iodine excretion levels were measured using Dry Digestion Ammonium Persulfate and Infant Development were assessed using a Pre-Screening Appraisal Questionnaire (KPSP). The maternal UIE median level was then correlated with the infant’s developmental status, using the Spearman test. The results showed that the mother’s UIE level was optimal (173,5 ppm). There were nine mothers (30%) had optimal UIE status, but infant development status in the dubious category of 12 (40%). Result of correlation test between mother UIE level with infant development status showed p = 0,428; r = 0.150. It was concluded that there was no significant association between UIE of breastfeeding mothers and developmental status of infants aged under two years.
Pengaruh Pemberian VCO (Virgin Coconut Oil) terhadap Gambaran Histologi Tiroid Tikus Putih (Rattus norvegicus) Habbatul Haqiqoh; Sri Nabawiyati Nurul Makiyah
Mutiara Medika: Jurnal Kedokteran dan Kesehatan Vol 8, No 1 (2008)
Publisher : Universitas Muhammadiyah Yogyakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18196/mmjkk.v8i1.1652

Abstract

One of dietary alternative which can be used for overcoming thyroid dysfunction is by using Virgin Coconut Oil (VCO). The aim of this research is to know the efficacy of alternative medicine, especially VCO to improve thyroid function which can be seen from histology appearance on rat. This research is preclinical posttest only experiment with randomized control group design. The subject of this research are 25 male Spraque-Dawley strain Rattus norvegicus, 4 months and ± 300 grams body weight. Rats were divided into 5 groups : negative and positive control, and three treatment groups. Positive control group and treatment groups will given fat first until them obese. After that, the VCO is given to three treatment groups. The dosage given was conversion of human dosage, 50 ml/day, 25 ml/day and 12,5 ml/day and will be converse in the end of week. VCO given orally everyday for 28 day, after that surgical were done to the rat, then histological thyroid object are made. The observation is seen from its follicular epithel height, follicular diameter and the colloid mass on its lumen. The data was analyzed using ANOVA test continued with Tukey test. The significant result just only shown from the diameter of follicular cells. The magnificent differences were between negative control group and treatment group which get 50 ml/day of VCO; and among positive control group with in all treatment groups. Based on this research we can conclude that VCO has significant role to improved the thyroid gland activities in white rats.Salah satu alternatif pengobatan alami untuk mengatasi masalah gangguan tiroid adalah VCO (Virgin Coconut Oil). Penelitian ini bertujuan untuk mengetahui manfaat VCO dalam membantu meningkatkan kerja kelenjar tiroid, dilihat dari gambaran histologi tiroid pada tikus putih. Metode penelitian adalah eksperimental praklinik dengan rancanganposttest randomized control group. Sampel penelitian berjumlah 25 ekor tikus putih (Rattus norvegicus) galur Spraque- Dawley jantan, umur 4 bulan dan berat badan rata-rata 300 gram. Tikus dibagi menjadi 5 kelompok yaitu kontrol positif dan negatif serta tiga kelompok perlakuan yang diberi VCO. Kelompok kontrol positifdan ketiga kelompok perlakuan digemukkan terlebih dahulu hingga mengalami obesitas. Setelah itu diberikan VCO peroral, dengan dosis hasil konversi dari dosis manusia, yaitu 50 mL/hari, 25 mL/hari, dan 12,5 mL/hari. VCO diberikan peroral setiap hari selama 28 hari kemudian tikus diterminasi dan dibuat preparat histologi tiroid. Pengamatan preparat dilakukan dengan melihat tinggi epitel sel folikel tiroid, diameter folikel, serta persentase massa koloid dalam lumen sel folikel. Untuk analisis data digunakan uji ANOVAdilanjutkan dengan uji Tukey. Hasil signifikan hanya terdapat pada gambaran diameter folikel sel kelenjar tiroid. Perbedaan tampak nyata antara kelompok kontrol negatif dengan kelompok perlakuan dosis 50 mL/hari dan kelompok kontrol positif, serta antara kelompok kontrol positif terhadap semua kelompok perlakuan yang diberi VCO. Berdasarkan penelitian ini disimpulkan bahwa minyak kelapa murni dapat membantu meningkatkan kerja kelenjar tiroid pada tikus putih.
Angioedema in Systemic Lupus Erythematosus (SLE) in Emergency Setting: A Case Report Nur Mujaddidah Mochtar; Ricky Indra Alfaray; Detty Irawaty; Yelvi Levani
Mutiara Medika: Jurnal Kedokteran dan Kesehatan Vol 20, No 2 (2020): July
Publisher : Universitas Muhammadiyah Yogyakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18196/mm.200252

Abstract

AbstractSystemic Lupus Erythematosus (SLE) is an autoimmune disease which causes chronic inflammation with its characteristics of the formation of autoantibody that attacks nuclear antigen. This disease may damage multisystem organs, and its diagnoses are barely implemented in the Emergency Department. However, cases of angioedema on SLE patient are quite uncommon not only in Indonesia but also globally. This article report an interesting case of 20 years old woman who came to the Emergency Department of Siti Khodijah Sepanjang Hospital with a complaint of swollen lips for three days. The complaint and examination led to the diagnosis of SLE. However, because the incidence rate of angioedema on SLE is low, doctors tend to unconsider the appropriate diagnosis management and administration on this breathing problem caused by SLE.Keywords: Systemic Lupus Erythematosus, angioedema, emergency AbstrakSistemic Lupus Eritematosus (SLE) adalah penyakit autoimun yang menyebabkan peradangan kronis dengan karakteristik pembentukan autoantibodi yang menyerang antigen. Penyakit ini dapat merusak organ multisistem, dan diagnosisnya hampir tidak diterapkan di Unit Gawat Darurat. Namun, kasus angioedema pada pasien SLE sangat jarang tidak hanya di Indonesia tetapi juga secara global. Artikel ini melaporkan kasus menarik dari wanita berusia 20 tahun yang datang ke Unit Gawat Darurat Rumah Sakit Siti Khodijah Sepanjang dengan keluhan bibir bengkak selama tiga hari. Keluhan dan pemeriksaan mengarah pada diagnosis SLE. Namun, karena tingkat kejadian angioedema pada SLE rendah, dokter cenderung tidak mempertimbangkan manajemen diagnosis yang tepat dan administrasi pada masalah pernapasan yang disebabkan oleh SLE ini.Kata kunci: Sistemik Lupus Eritematosus, angioedema, gawat darurat

Filter by Year

2001 2025


Filter By Issues
All Issue Vol. 25 No. 1 (2025): January Vol 24, No 2 (2024): July Vol 24, No 1 (2024): January Vol 23, No 2 (2023): July Vol 23, No 1 (2023): January Vol 22, No 2 (2022): July Vol 22, No 1 (2022): January Vol 21, No 2 (2021): July Vol 21, No 1 (2021): January Vol 21, No 1: January 2021 Vol 20, No 2: July 2020 Vol 20, No 2 (2020): July Vol 20 No 1: January 2020 Vol 20, No 1 (2020): January Vol 20, No 1: January 2020 Vol 19, No 2: July 2019 Vol 19, No 2 (2019): July Vol 19 No 2: July 2019 Vol 19, No 1 (2019): January Vol 19, No 1: January 2019 Vol 19 No 1: January 2019 Vol 18 No 2: July 2018 Vol 18, No 2: July 2018 Vol 18, No 2 (2018): July Vol 18 No 1: January 2018 Vol 18, No 1 (2018): January Vol 18, No 1: January 2018 Vol 17, No 2 (2017): July Vol 17, No 2: July 2017 Vol 17 No 2: July 2017 Vol 17 No 1: January 2017 Vol 17, No 1: January 2017 Vol 17, No 1 (2017): January Vol 16 No 2: July 2016 Vol 16, No 2: July 2016 Vol 16, No 2 (2016): July Vol 16, No 1: January 2016 Vol 16, No 1 (2016): January Vol 16 No 1: January 2016 Vol 15, No 2 (2015) Vol 15, No 2 (2015) Vol 15, No 2 (2015): July Vol 15, No 1 (2015) Vol 15, No 1 (2015): January Vol 15, No 1 (2015) Vol 14, No 2 (2014) Vol 14, No 2 (2014): July Vol 14, No 1 (2014) Vol 14, No 1 (2014) Vol 14, No 1 (2014): January Vol 13, No 3 (2013) Vol 13, No 3 (2013) Vol 13, No 2 (2013) Vol 13, No 2 (2013) Vol 13, No 1 (2013) Vol 13, No 1 (2013) Vol 12, No 3 (2012) Vol 12, No 3 (2012) Vol 12, No 2 (2012) Vol 12, No 2 (2012) Vol 12, No 1 (2012) Vol 12, No 1 (2012) Vol 11, No 3 (2011) Vol 11, No 3 (2011) Vol 11, No 2 (2011) Vol 11, No 2 (2011) Vol 11, No 1 (2011) Vol 11, No 1 (2011) Vol 10, No 2 (2010) Vol 10, No 2 (2010) Vol 10, No 1 (2010) Vol 10, No 1 (2010) Vol 9, No 2 (2009) Vol 9, No 2 (2009) Vol 9, No 2 (s) (2009) Vol 9, No 2 (s) (2009) Vol 9, No 1 (2009) Vol 9, No 1 (s) (2009) Vol 9, No 1 (s) (2009) Vol 9, No 1 (2009) Vol 8, No 2 (2008) Vol 8, No 2 (s) (2008) Vol 8, No 2 (s) (2008): Oktober Vol 8, No 2 (s) (2008): Juli Vol 8, No 2 (2008) Vol 8, No 1(s) (2008): April Vol 8, No 1 (2008) Vol 8, No 1 (S) (2008): Januari Vol 8, No 1 (2008) Vol 8, No 1 (s) (2008): April Vol 8, No 1 (s) (2008) Vol 7, No 2 (2007) Vol 7, No 2 (2007) Vol 7, No 2 (s) (2007): Oktober Vol 7, No 2 (s) (2007) Vol 7, No 2 (s) (2007): Juli Vol 7, No 1 (2007) Vol 7, No 1 (s) (2007) Vol 7, No 1 (2007) Vol 7, No 1 (s) (2007) Vol 6, No 2 (2006) Vol 6, No 2 (2006) Vol 6, No 1 (2006) Vol 6, No 1 (2006) Vol 5, No 2 (2005) Vol 5, No 2 (2005) Vol 5, No 1 (2005) Vol 5, No 1 (2005) Vol 4, No 2 (2004) Vol 4, No 2 (2004) Vol 4, No 1 (2004) Vol 4, No 1 (2004) Vol 3, No 2 (2003) Vol 3, No 2 (2003) Vol 3, No 1 (2003) Vol 3, No 1 (2003) Vol 2, No 2 (2002) Vol 2, No 2 (2002) Vol 2, No 1 (2002) Vol 2, No 1 (2002) Vol 1, No 2 (2001) Vol 1, No 2 (2001) More Issue