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POSSESSION, REVIEW FROM CULTURAL AND PSYCHIATRY
Sri Diniari, Ni Ketut;
Hanati, Nyoman
Medicina Vol 43 No 1 (2012): Januari 2012
Publisher : Medicina
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Possession is a culture related syndrome, commonly found in Indonesia including Bali. We can see this event in religion and cultural ceremony and at other times at school, home, and in society. This syndrome consist of temporary loss of self identification and environment awareness; in several events a person acts as if he/she was controlled by other being, magic force, spirit or ‘other forces’. There are still several different opinions about trance-possession, whether it is related to certain culture or is a part of mental disorder. DSM-IV-TR and PPDGJ-III defined trance-possession as mental disorder (dissociative) for involuntary possession, if it is not a common activity, and if it is not a part of religion or cultural event. (MEDICINA 2012;43:37-40).
THE INCIDENCE OF IN-HOSPITAL MALNUTRITION IN CHILDREN AT SANGLAH DENPASAR HOSPITAL
Lanang Sidiartha, I Gusti
Medicina Vol 43 No 1 (2012): Januari 2012
Publisher : Medicina
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In-Hospital Malnutrition cause by longer length of stay is still as a health problem. The objective of the study is to find out the incidence of In-hospital malnutrition and the association with sex, age, malnutrition on admission, diagnosis and length of stay. The cohort retrospective study was done based on the medical record from The Nutrition and Metabolic Disease Division, Department of Child Health, Udayana University/Sanglah Hospital Denpasar from June 2008 to February 2009 period. In-hospital malnutrition was confirmed if the body weight decreased ? 2% in a week or ? 5% in a month or ? 10% in 6 months during hospitalized. Statistical analysis was done to find out the association between In-hospital malnutrition and sex, age, diagnosis, malnutrition on admission, and length of stay. The odds ratio was counted and the statistical significant was decided if p value < 0.05. There were 78 over 460 children (17%) met the criteria of In-hospital malnutrition. Logistic regression showed that after adjusting for sex, age, malnutrition on admission, and diagnosis; the length of stay longer than 7 days (OR = 3.7, CI 95% 2.1 – 6.4) was statistically associated with In-hospital malnutrition in the final model. The study concludes that the incidence of In-hospital malnutrition in Sanglah Hospital was still high and it was associate with length of stay longer than 7 days. (MEDICINA 2012;43:15-18).
MOLECULAR CYTOGENETIC REVIEW OF COMPLETE HYDATIDIFORM MOLE
Mahendra, Agung Nova
Medicina Vol 43 No 1 (2012): Januari 2012
Publisher : Medicina
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Complete Hydatidiform Mole (CHM) is a pathologic pregnancy characterized by placental development regulatory genes defect. CHM is of significant importance to be characterized because of its relatively high potential to become malignant. Misdiagnosis is relatively common when histological method or cell ploidy determination is used as diagnostic tool. Knowledge of CHM genesis and genetic constitution serves as a basis to establish accurate diagnosis, and this can be achieved through the use of molecular cytogenetical approaches. This article is aimed on giving deeper understanding of CHM genesis from the perspective of molecular cytogenetics. By using molecular cytogenetical characterization, researchers found 2 CHM variants, namely BiCHM (Biparentally-inherited CHM) and AnCHM (Androgenetic CHM) with complex genetic heterogeneity. These findings also contribute to the improvement of molecular diagnostics, chemotherapeutics, genetic counselling, and gene therapy. (MEDICINA 2012;43:41-45).
CORRELATION BETWEEN PENIS LENGTH AND ANTHOPOMETRY OF 5 YEAR OLD CHILDREN
Kurnia Indrawan, Doddy;
Suryawan, Bikin;
Sidiartha, Lanang;
*, Arimbawa
Medicina Vol 43 No 1 (2012): Januari 2012
Publisher : Medicina
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Short penis still a problem for parents. Penis lenght is associated with weight and considered abnormal in obese children. The purpose of this study was to find out the correlation between penis length and the anthropometry children aged 5 years. A cross sectional study was conducted, at the Division of Endocrinology, Department of Child Health, Medical Faculty of Udayana University, Sanglah Hospital Denpasar, during October 2010, at TK Sayang Ibu Sanglah Hospital. The calculation of the sample with a correlation coefficient of weight and height obtained 9 people, taking in consecutive sampling and analyzed with Pearson’s correlation. The mean body weight was 23.6 (SD 7.70) kg; mean child height was 108.4 (SD 5.3) cm, and 47.1% were obese. The mean length of the penis was 4.7(SD1.30) cm. The correlation between weight and penis lenght was strong negative (r = -0.876; P = 0.000) and between penis length and height was r = -0.597; P = 0,011.There was a strong negative correlation between body weight and penis length and also negative correlation between penis length and height in kindergarten children. (MEDICINA 2012;43:19-22).
A AND D SURFACTAN PROTEINS IN LUNG IMMUNE SYSTEM
Linawati, Ni Made
Medicina Vol 43 No 1 (2012): Januari 2012
Publisher : Medicina
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The surfactant associated proteins of the lung are component of lung innate immunity. Its functions in host defence is mediated by surfactant associated protein A and D. surfactant associated protein A and D are collectins familly, both synthesized and secreted by many cells in different parts of our body. (MEDICINA 2012;43:46-48).
THE USE COXIB IN NOCICEPTIVE PAIN MANAGEMENT
Eko P, Thomas
Medicina Vol 43 No 1 (2012): Januari 2012
Publisher : Medicina
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The advent of the Coxibs (COX-2 inhibitor) represented a significant theorical breakthrough in non-steroid anti inflammatory drugs (NSAIDs) treatment. The use of NSAIDs is limited by by adverse reactions, especially their gastrointestinal (GI) toxicity. The selective COX-2 inhibitors were originally developed to minimize the adverse effect of conventional NSAIDs while maintaining the same analgesic and anti-inflammatory effects. Although the benefit of coxibs in GI tract has been established the cardiovascular (CV) safety of coxibs still debatable. Several studies have reported an increased incidence of cardiovascular related morbidity and mortality with the use of COX-2 inhibitor. A definitive answer to whether or not these drugs increase CV risk can only really be derived from multicenter purpose-designed, prospective randomized control trials. Circumstances under which COX-2 selective inhibitor maybe appropriate are in patients at high GI risk and in patients who did not respond to multiple conventional NSAIDs. Health care providers must consider the efficacy, GI and CV risks, concomitant medications and costs when determining the appropriateness of COX-2 selective inhibitor therapy.(MEDICINA 2012;43:23-30).
WOUND HEALING IN DIABETIC ULCER
Putra Pramana, Ida Bagus;
Yasa, Ketut Putu
Medicina Vol 43 No 1 (2012): Januari 2012
Publisher : Medicina
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The mechanism of wound healing is a complex mechanism and involves a variety of cells. Injury is defined as a disruption of normal structure and function. Various types of growth factors and cytokines such as platelet derived growth factor and transforming growth factor beta involved in the mechanism of wound healing. There are four phases of wound healing mechanisms : hemostasis, inflammatory, proliferative, and remodeling. Diabetic ulcers is one major complication, occurring in 15% of patients with diabetes mellitus (DM) and as much as 84% of patients with diabetic ulcers require amputation action. In DM patients there is a failure in normal wound healing mechanisms. Various histopathological studies showed elongation phase of inflammation in patients with diabetes mellitus, thus inhibiting the formation of granulation tissue. Increased blood sugar levels will lower the expressin of perlecan, increased advanced glycation endproducts, decreased the formation of nitric oxide (by ± 67%), changes in the structure and function of fibroblasts and increased activity of matrix metalolproteinases, it will cause distruption of the normal wound healing mechanisms. (MEDICINA 2012;43:49-53).
EFICACY OF ZINC SUPLEMENTATION AS ADJUVANT THERAPY IN CHILDREN 6- 60 MONTHS OLD WITH PNEUMONIA
Sidiartha, I Gusti Lanang;
Gede Suandi, I Kompiang;
Subanada, Ida Bagus;
Siadi Purniti, Ni Putu;
Karsana, AA Raka
Medicina Vol 43 No 1 (2012): Januari 2012
Publisher : Medicina
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Morbidity and mortality rates of childhood pneumonia is still high, especially in developing countries. Many efforts are done to decrease the morbidity and mortality rate and one of them is zinc supplementation as adjuvant therapy. The aim of the study is to find the effectiveness of zinc supplementation as adjuvant therapy in childhood pneumonia. The randomized controlled trial study was done on 33 patients with pneumonia at Sanglah Hospital Denpasar. Intervention group received 20 mg zinc elemental each day. Time for recovery and length of hospital stay were compared between zinc and placebo groups. The different was significant if the P value < 0.05. Time for recovery in zinc group and placebo group was 4 days and 3.4 days, respectivelly. Length of hospital stay was 5.9 days in zinc group and 5.6 days in placebo group. The different was not significant. Conclusion is zinc supplementation as adjuvant therapy in childhood pneumonia is not effective to decreased the time for recovery and length of hospital stay. (MEDICINA 2012;43:9-14).
INHIBITOR IN HEMOPHILIA
K Yantie, Veny;
K, Ariawati
Medicina Vol 43 No 1 (2012): Januari 2012
Publisher : Medicina
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Hemophilia is an X-linked recessive disorder which is believed to affect approximately one in 5000-10.000 male birth. An inhibitor is a type of antibody. In hemophilia patients type A, B, and C are directly destroy factor VII, IX, and XI. The incidence of antibody development in hemophilia A is between 20% and 40%, hemophilia B inhibitors only 1 to 6 %. The presence of an inhibitor is usually confirmed using a specific blood test called the Bethesda inhibitor assay. The treatment of hemophilic bleeding in a person with an inhibitor can be a challenging experience. Patients hemophilia with inhibitor have poor prognostic. (MEDICINA 2012;43:31-36).
KOREA SYDENHAM DAN KARDITIS TERSEMBUNYI PADA SEORANG ANAK PEREMPUAN USIA 9 TAHUN
Widyanti, Putu Ayu;
Gunawijaya, Eka;
Sutriani, Dewi
Medicina Vol 43 No 1 (2012): Januari 2012
Publisher : Medicina
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Korea Sydenham adalah bentuk paling umum dari gerakan korea yang diperoleh pada masa kanak-kanak, dan merupakan salah satu kriteria diagnostik utama demam rematik. Korea Sydenham ditandai dengan gerakan involunter yang menghilang saat tidur, ketidakstabilan emosional, dan hipotonia. Kasus adalah anak perempuan berumur 9 tahun dengan gerakan coreatic (gerakan involunter pada lengan dan kaki). Gerakan tersebut juga ditemukan pada lidah sehingga pasien sulit untuk berbicara. Pasien juga memiliki ketidakstabilan emosi, dan kelemahan otot. Riwayat trauma disangkal. Pada pemeriksaan fisik ditemukan murmur di daerah apex jantung, holosistolik, derajat 2/6, meniup, dan menyebar sepanjang aksila. Pada echocardiography didapatkan regurgitasi mitral moderat (MR) dan regurgitasi aorta (AR) karena karditis. Diagnosisnya adalah Korea Sydenham dan karditis. Pasien diterapi dengan erythomicin 250 mg empat kali sehari selama 10 hari, dan eritromisin 250 mg oral dua kali sehari untuk profilaksis. Untuk terapi simtomatik diberikan haloperidol 2 mg dua kali sehari dan trihexyphenidil 0.5 mg tiga kali sehari. Respon terapi dan prognosis baik. (MEDICINA 2012;43:54-59).