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Published by Universitas Lambung Mangkurat

ISSN : 14120550 EISSN : 25485660 DOI : http://dx.doi.org/10.20527

Biochemistry, Genetics & Molecular Biology Health Professions Immunology & microbiology Medicine & Pharmacology Public Health

Berkala Kedokteran is a journal contains scientific articles from original research and literature review in medical and health scope. It is published twice in a year, on February and September.

Arjuna Subject : Kedokteran - Kedokteran (Lain-Lain)

Articles 478 Documents

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Mesentrial Cyst Lymphangioma in 3-Year-Old Girls: A Case Report Hafni Zuchra Noor; Nunik Agustriani
Berkala Kedokteran Vol 16, No 2 (2020)
Publisher : Fakultas Kedokteran Universitas Lambung Mangkurat

Abstract: Mesenterial cysts are rare tumors, incidence 1: 100,000-200,000. We report the case and the treatment. Case report, 3-year-old woman with complaints of a lump in the abdomen. Complaints in the last 1 year ago, sometimes she felt pain, physical examination showed a lump of cystic impression with a size of ± 5x10 cm in the epigastric region, mobile, firm boundary. It can be diagnosed with a suspected intra-abdominal tumor with a mesenterial cyst, differential diagnosis of teratoma. Surgery was performed and a mass was found in retroperitoneal with a size of ± 20x5 cm up to the pelvic cavity, cystic and mobile, the mass could not be taken at all, we decided to do marsupialization, and left kidney is not visible. Postoperative diagnosis is retroperitoneal (type IV) mesenterial cyst lymphangioma with agenesis ren sinistra. Mesenterial cyst Lymphangioma is a tumor that is very rarely found and is benign. For a good prognosis, it depends on the type and therapy that is performed. Keywords: Mesenterial cyst lymphangioma, a tumor in children, mesenterial tumor

Potentials of Betel Leaf Infusion (Piper betle L), Lime Peel Extract (Citrus aurantifolia) and Bundung Extract (Actinoscirpus grossus) as Candidiasis Therapy Darini Kurniawati; Kunti Nastiti
Berkala Kedokteran Vol 16, No 2 (2020)
Publisher : Fakultas Kedokteran Universitas Lambung Mangkurat

Abstract: Candidiasis is an infection caused by the fungus Candida, especially Candida albicans. It often occurs in the mouth and sex organs, also in the nails, respiratory tract, digestive tract, and anus. Betel leaf stew is often used by people to gargle and clean the intimate organs. The nature of the betel leaf solution is easily oxidized and turns brown. Therefore, research needs to be done by mixing betel leaf (Piper betle L) with lime (Citrus aurantifolia) to maintain the color of betel leaf, coupled with natural ingredients that have antimicrobial properties, namely lime peel and bundung plants (Actinoscirpus grossus). With the hypothesis of the joining of three natural materials that have antimicrobial activity can strengthen the inhibitory activity of the fungus Candida albicans. This research was conducted by making a betel leaf infusion formulation, lime peel extract, and bundung extract with a concentration of 20%, 30%, 40%, and 50% which were then tested to determine the effect of the infusion formulation on the inhibitory activity of Candida albicans by the method spread on Saburoud Dextrose Agar media. Based on Zuraidah's research (2015), 80% and 100% betel leaf extraction has activity on Candida albicans. From the results of this study significant results were obtained at a concentration of 50% of a mixture of betel leaf infusion formulations, extracts of lime peel and bundung extract had the same inhibitory properties as the hand sanitizer antiseptic liquid against Candida albicans. Thus it can be concluded that the 50% test formulation of betel leaf infusion mixture with lime extract and bundung extract has greater potential than betel leaf extract alone as a candidiasis therapy. Keywords: Piper betle L, Citruss aurantifolia, Actinoscirpus grossus, Antiseptik, Kandidiasis, Candida albicans

Validity and Reliability of The Indonesian Modification of Score for Allergic Rhinitis Asti Widuri; Rizka Fakhriani
Berkala Kedokteran Vol 17, No 1 (2021)
Publisher : Fakultas Kedokteran Universitas Lambung Mangkurat

Abstract: Allergic rhinitis (AR) is a nasal inflammation caused by IgE-mediated reacions after inhaled the allergens. It’s characterized as symptoms of sneezing, airflow obstruction, nasal pruritus, and often clear nasal discharge. The prevalence of AR is about 5-40% in the general population and still rising. Multiple non-instrumental tests for AR were reported though few were validated. Score for Allergic Rhinitis (SFAR) is a valid instrument to screening AR. The purpose of this study was to perform adaptation and cultural translation and validation of the SFAR questionnaire for the Indonesian language. This was a cross sectional study to assess the validity and reliability of the Indonesian modification of Score for Allergic Rhinitis. The study conduct in 59 subjects. The Indonesian modification of SFAR instrument is valid and reliable as an instrument for screening AR with r values ranging from 0.345 to 0.730. Internal consistency shows that Cronbach's alpha is 0.803. The validation and reliability test of Indonesian modification of Score for Allergic Rhinitis was performed and valid and reliable as an instrument for assessing allergic rhinitis. Keywords: Allergic Rhinitis, Score for Allergic Rhinitis, Validity, Indonesian Version.

Pattern of Antibiotics Use in Adult Patients with Urinary Tract Infection (UTI) Hidayatul Kurniawati; Anisa Auliyanah
Berkala Kedokteran Vol 17, No 1 (2021)
Publisher : Fakultas Kedokteran Universitas Lambung Mangkurat

Abstract: Introduction: Urinary tract infection (UTI) is an infectious disease caused by the growth and proliferation of bacteria in the urinary tract, including infections in the bladder to the renal parenchyma with a certain number of bacteria in the urine. The use of antibiotics is therapy that commonly used to treat infectious diseases caused by bacteria. Irrational use of antibiotics can lead to bacterial resistance and toxicity. Objective: To determine the rationality of using antibiotics in adult patients with a urinary tract infection (UTI) in the X Hospital Yogyakarta from January-December 2017.Methods: This study is a non-experimental study with a descriptive observational study design and retrospective data collection. The sample of this study was inpatients with a diagnosis of urinary tract infection (UTI) and was recorded in the Medical Record X Hospital Yogyakarta for the period January-December 2017 which was included in the inclusion criteria. Results: Medical records that were included in the inclusion criteria were 61. The single most widely used antibiotic was ceftriaxone in 25 cases (44.64%) and the most widely used combination antibiotic was ceftazidime + levofloxacin in 2 cases (40%). The use of antibiotics with the right indication was 61 patients (100%), the right type was 61 patients (100%), the correct duration was 54 patients (88.52%), the right dose was 61 patients (100%), the right interval was 60 patients (98.36%) and the right route of administration was 61 patients (100%). Keywords: Urinary tract infection, antibiotic, rational

Diagnostic Approaches and Management of Subacute Sclerosing Panencephalitis in Children Nurul Hidayah; Andreas Budi Wijaya
Berkala Kedokteran Vol 16, No 2 (2020)
Publisher : Fakultas Kedokteran Universitas Lambung Mangkurat

Abstract: Subacute Sclerosing Panencephalitis (SSPE) is a progressive neurodegenerative disease that attacks the central nervous system, especially in the population of children and early adolescents, due to persistent measles virus infection. The incidence of SSPE is quite rare, and data shows that in developing countries it is still quite high compared to developed countries. Diagnosis is based on clinical, supporting examinations such as EEG, as well as increased antibodies against measles virus in serum and cerebrospinal fluid. Symptoms can include changes in behavior, myoclonus, memory problems, and persistent pyramidal or extrapyramidal movements. Management to date has not provided satisfactory results and is individualized. Most SSPE patients experience a progressive and gradual course, leading to death within 1-3 years. The challenge of SSPE in children is the approach to diagnosis and management. Until now, the approach to treating SSPE in children is still based on the pathophysiological mechanisms from several existing research studies. That why therapy guidelines for children with SSPE are still varied. This paper aims to discuss the topic of SSPE in children with a major focus on diagnostic and therapeutic approaches based on the latest scientific evidence. Keywords: Subacute Sclerosing Panencephalitis (SSPE), children, diagnosis, therapy

The Correlation of Hba1c Level With GSH-PX Enzyme Activity, AOPP, and MDA Levels in The Eye Lenses of Diabetic Cataract Patients Maria Winney Natania; Monica Claudia; Refita Maharani; Muhammad Ali Faisal; Triawanti Triawanti
Berkala Kedokteran Vol 16, No 2 (2020)
Publisher : Fakultas Kedokteran Universitas Lambung Mangkurat

Abstract: Diabetes Mellitus (DM) is known to accelerate cataractogenesis because it may cause hyperglycemia-induced stress oxidative in the eye lens. HbA1c test can be performed to monitor glycemic control. Glutathione peroxidase (GSH-Px) is an enzyme that scavenges and prevents the formation of free radical. Advanced Oxidation Protein Products (AOPP) is a marker to estimate the degree of oxidative protein modification. Malondialdehyde (MDA) can reflect cells damage. This study was an observational analytic study, conducted in September 2019-January 2020, and aimed to determine the correlation of HbA1c level with GSH-Px enzyme activity, AOPP, and MDA levels in the eye lenses of diabetic cataract patients. Data of HbA1c level and eye lenses sample was obtained from 29 cataract patients with DM who underwent phacoemulsification surgery in Ulin and Bhayangkara Hospital in Banjarmasin and fulfilled the inclusion criteria. Spearman’s correlation test showed that there was no significant correlation of HbA1c with GSH-Px activity (p=0,095), AOPP (p=0,084), and MDA (p=0,084) levels in the eye lens of diabetic cataract patients. Keywords: Diabetes mellitus, cataract, HbA1c, glutathione peroxidase, AOPP, MDA

Correlation between Dimension of Fingers Phalannx Proximal and Height in the Age of 18-45 Years Old Talitha Lailatul Hafizah; Dedi Afandi; Chunin Widyaningsih; Fajri Marindra Siregar
Berkala Kedokteran Vol 16, No 2 (2020)
Publisher : Fakultas Kedokteran Universitas Lambung Mangkurat

Abstract: Height is one of the data needed in forensic identification process of a remains that is difficult to identify in an incomplete condition. Height estimation can be determined by the proximal phalanx of the fingers which are long bones. This study was conducted on 113 men and 125 women in several places in Riau Province age 18 - 45 years. The height and dimensions of the proximal phalanx of the fingers are measured to get the correlation and linear regression formula for height. There are 6 dimensions measured on the fingers of the left and right hand. The study design was cross sectional. The statistical test used is Pearson correlation to determine the correlation between dimensions of the proximal phalanx on fingers with height and linear regression analysis for height regression formula. The results show that some dimensions of the proximal phalanx of the fingers are significantly correlated with height. Keywords: identification, height, dimensions of the proximal phalanx bone fingers, correlation, regression formula.

Thoracic Gunshot Wound with Vascular Lesion Ahmad Adityawarman; Ahmad Ghozali
Berkala Kedokteran Vol 17, No 1 (2021)
Publisher : Fakultas Kedokteran Universitas Lambung Mangkurat

Abstract: The thoracic gunshot wounds may cause high morbidity and mortality, especially if accompanied by vascular injuries. Therefore, immediate management and precise decision are needed. A 35-year-old man who was referred from the regional hospital presented with thoracic gunshot wound and a history of hemorrhagic shock. A projectile was found through the chest wall and caused axillary artery rupture. The patient underwent exploratory thoracotomy and axillo-brachial artery bypass using a great saphenous vein graft. The patient's postoperative condition showed improvement in hemodynamic and distal limb perfusion. Keywords: Chest trauma, gunshot wound, axillary artery, vascular injury

Potential of Pectin in Lemon’s and Bali Orange’s Peel as Antidislipidemia and Antioxidant in Hypercholesterolemia Rats (Rattus novergicus) Noer Kumala Indahsari; Aristanto Aristanto; Rio Rio
Berkala Kedokteran Vol 16, No 2 (2020)
Publisher : Fakultas Kedokteran Universitas Lambung Mangkurat

Abstract: Dyslipidemia is a lipid metabolism disorder characterized by an increase or decrease in plasma lipid fractions. Lemon’s and Bali Orange’s Peels, which are usually discarded, can be used because they contain pectin compounds. The presence of pectin compounds contained in the Lemon and Bali oranges Peels is expected to potentially reduce the risk factors for cardiovascular disease. This research method was conducted with pure experimental, namely One Group Pre-Test-Post Test Design. With 5 groups of white rats, the first was a positive control group which was only given normal food, the second was a negative control group which was given hypercholesterolemia and the third group was the treatment group who were given Lemon orange peel extract 10%, Bali orange peels extract 10% and a mixture Lemon and Bali orange peel extract 10%. The results of this study were obtained that the administration of Lemon orange peel ethanol extract and Balinese orange peel can effectively reduce total cholesterol levels, from 181.87 mg / dL to 69.29 mg / dL, down around 61.91%, HDL levels are almost the same, levels LDL decreased from 56.76 mg / dL to 45.71 mg / dl, meaning around 19.47%, Triglyceride levels decreased from 192.50 mg / dL to 77.83 mg / dL, which was around 59.57%, levels MDA decreased from 8.19 mg / dL to 6.37 mg / dL, which is down about 22.22% in white rats (Rattus novergicus) made hypercholesteroalmia. Ethanol extract of Lemon and Bali orangse peels containing pectin can effectively reduce total cholesterol, LDL, HDL, Trygliceryde, and Malodialdehyd (MDA) Levels Keywords: Hypercholesterolamia, Pectin, Antidislipidemia, and Antioxidant

Mean Platelet Volume and Platelet Distribution Width as Diagnosis Markers of Acute Perforated Appendicitis in Pediatric Patients Rahmi Noorhayati; Wahyu Wardhana Wardhana
Berkala Kedokteran Vol 16, No 2 (2020)
Publisher : Fakultas Kedokteran Universitas Lambung Mangkurat

Abstract: Symptoms and findings in acute perforated appendicitis (APA) may not always typical in children, becomes difficult to establish the diagnosis preoperatively. Rapid and accurate diagnosis is important to reduce the risk of sepsis and even death. Another biomarkers for diagnosis are needed. This study investigated the diagnostic accuracy of indicators of platelet activation, namely mean platelet volume and platelet distribution width, in children with non perforated acute appendicitis (NPAA) and APA. This retrospective study compared 15 patients with APA (Group I), 15 patients with NPAA (Group II) between January 2016 to December 2018. Patient white blood cell (WBC) count, platelet (PLT) count, MPV, PDW, and hematocrit (HCT) were analyzed. Receiver operating characteristic (ROC) curves were used to evaluate the sensitivity and specificity of these indices in AP. Positive correlation was found between MPV and the degree of AP; as well as negative correlation between PDW and degree of AP. This is the first study to assess the MPV and PDW in pediatric patients with AP. This study showed the MPV is reduced and the PDW is normal in patients with AP. A decreased MPV value could serve as a marker to diagnose AP preoperatively. More studies are needed to establish relationship between PDW and MPV with AP. Keywords: Appendicitis perforations; Mean Platelet Volume; Platelet distribution width

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Contact Name
Eko Suhartono

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esuhartono@ulm.ac.id

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+6281251126368

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jbk@ulm.ac.id

Editorial Address
Jalan Veteran No.128 Banjarmasin

Location
Kota banjarmasin,

Kalimantan selatan

INDONESIA

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Home Page

OAI Link

Editorial Team

Contact

Reviewer

Google Scholar

Contact Name Eko Suhartono

Contact Email esuhartono@ulm.ac.id

Phone +6281251126368

Journal Mail Official jbk@ulm.ac.id

Editorial Address Jalan Veteran No.128 Banjarmasin

Location Kota banjarmasin, Kalimantan selatan INDONESIA

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Contact Name
Eko Suhartono

Contact Email
esuhartono@ulm.ac.id

Phone
+6281251126368

Journal Mail Official
jbk@ulm.ac.id

Editorial Address
Jalan Veteran No.128 Banjarmasin

Location
Kota banjarmasin,

Kalimantan selatan

INDONESIA