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INDONESIA
MNJ (Malang Neurology Journal)
Published by Universitas Brawijaya
ISSN : 24076724     EISSN : 24425001     DOI : -
Core Subject : Science,
Neuroscience
Malang Neurology Journal is a peer-reviewed and open access journal that focuses on promoting neurological sciences generated from basic neurosciences and clinical neurology. This journal publishes original articles, reviews, and also interesting case reports. Brief communications containing short features of medicine, latest developments in diagnostic procedures of neurology disease, treatment, or other health issues related to neurology that is important also acceptable. Letters and commentaries of our published articles are welcome.
Arjuna Subject : -
Articles 297 Documents
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PANCOAST TUMOR PRESENTING WITH HORNER SYNDROME: A CASE REPORT Raden Andi Ario Tedjo; Hillary Hillary; Vivienne Tjung; Stefanus Erdana Putra; Muhammad Hafizhan
MNJ (Malang Neurology Journal) Vol. 9 No. 2 (2023): July
Publisher : PERDOSSI (Perhimpunan Dokter Spesialis Saraf Indonesia Cabang Malang) - Indonesian Neurological Association Branch of Malang cooperated with Neurology Residency Program, Faculty of Medicine Brawijaya University, Malang, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.mnj.2023.009.02.18

Abstract

Case Report: A 50-year-old man was referred to Dr. Moewardi General Hospital with history of right chest pain that radiate to the right back and hand for 2 months. His complaint did not improve with medication and physical therapy. On physical examination we observed multiple nodules on the right axilla, scapula, and colli region. Neurological examination revealed right sided partial ptosis, anisocoria, ipsilateral weakness, and ipsilateral allodynia, and anhidrosis T1 dermatome. CT-scan showed a right lung mass in the superior lobe of the apical segment. The diagnosis of Horner syndrome is then established caused by multiple lymphadenopathies. His symptoms then relieved after lymphadenectomy. Conclusion: Horner syndrome, characterized by ipsilateral pupillary anisocoria, ptosis and anhidrosis, is one of the complications of Pancoast tumor invasion to the sympathetic nervous system in the C8, T1, and T2 nerve territory.
CLINICAL CHARACTERISTICS OF LACUNAR ISCHEMIC STROKE PATIENTS Anindyta Murfia Khairunnisa; Lisda Amalia; Eppy Buchori Aristiady; Harry Galuh Nugraha; Asep Nugraha Hermawan
MNJ (Malang Neurology Journal) Vol. 9 No. 2 (2023): July
Publisher : PERDOSSI (Perhimpunan Dokter Spesialis Saraf Indonesia Cabang Malang) - Indonesian Neurological Association Branch of Malang cooperated with Neurology Residency Program, Faculty of Medicine Brawijaya University, Malang, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.mnj.2023.009.02.9

Abstract

Background: Stroke is the leading causes of death and disability in the world. Ischemic stroke covered 85% of stroke types. Based on the subtypes of ischemic stroke, lacunar ischemic stroke encompassed 20% of them. Knowing the characteristics help physicians to diagnose patients clinically and offer management to treat risk factors. Objective: This study aimed to know the characteristics of lacunar ischemic stroke based on patients risk factors, ischemic location on CT-scan, clinical syndrome, and NIHSS score. Methods: Using retrospective analytical study with cross sectional approach, medical record data from 2019-2022 were collected from RSUP DR. Hasan Sadikin Bandung. Results: From 60 patients, 35% (21) are 55-64 years old. Both sexes are equally distributed. 50 patients (83.3%) have multiple risk factors. Out of 60 patients, 57 (95%) have hypertension, 8 (13.3%) have diabetes mellitus, 44 (73.3%) have dyslipidemia, 6 (10%) have hyperuricemia, and 14 (23.3%) smoke. On admission, out of 60 patients, 34 (56.7%) have mild stroke, 23 (38.3%) have moderate stroke, 2 (3.3%) have moderate to severe stroke, and 1 (1.7%) has severe stroke. 44 (73.3%) out of 60 patients have pure motor hemiparesis. 41 (68.3%) out of 60 patients have basal ganglia ischemic. Conclusion: Lacunar ischemic stroke patients were equally distributed in sex with peak incidence occur between 55-64 years old. Most patients have multiple risk factors, basal ganglia lesion, pure motor hemiparesis, and history of hypertension, dyslipidemia, and smoking. On admission, most patients have mild stroke, followed by moderate stroke.
THE POTENTIAL OF STEM CELL THERAPY AS A MANAGEMENT OF CHRONIC PAIN: A SYSTEMATIC REVIEW Putu Yogi Pramana; Agung Bagus Sista Satyarsa; Ida Ayu Sri Wijayanti; Anak Agung Raka Sudewi
MNJ (Malang Neurology Journal) Vol. 9 No. 2 (2023): July
Publisher : PERDOSSI (Perhimpunan Dokter Spesialis Saraf Indonesia Cabang Malang) - Indonesian Neurological Association Branch of Malang cooperated with Neurology Residency Program, Faculty of Medicine Brawijaya University, Malang, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.mnj.2023.009.02.15

Abstract

Background: Stem cells has previously been used with promising results as a therapeutic modality for neurodegenerative diseases and pain but has recently been introduced as a treatment for chronic pain. Objective: This study aims to review the available literature on the role of stem cell therapy as a treatment for chronic pain. Methods: A review of clinical reports using the PRISMA (Preferred Reporting Items for Systematic Review and Meta-Analysis) method published in Pubmed, EMBASE (Excerpta Medica Database), and ScienceDirect were used from 2013 to 2023, and The search tool was used to locate and enroll patients for ongoing, presently active clinical studies. The search terms used included “chronic pain,” “therapy,” “prosedure” “neuropathic,” “discogenic,” “modality,” “musculoskeletal” and “stem cell.” The research was then carried out to assess the quality of the study using the Critical Appraisal Skills Program questionnaire. Results: There were around 186 studies related to the keyword, and only about 11 studies that met the inclusion criteria included in this article were obtained. Based on the results of the study, it was found that the role of stem cell therapy in the form of MSC and ADS, which was used, had a significant effect as a chronic pain therapy in patients. A decrease in the quality of pain was obtained based on VAS (Visual Analog Scale), ODI (Oswestry Disability Index), and NRS (Numeric Rating Scale) assessments as well as an increase in patient function. Conclusion: Although current research suggesting the use of mscs as a novel therapy method for disc, neuropathic, and musculoskeletal pain, further studies are required to demonstrate the efficacy as well as security of this modality
THE DEPICTION OF GENERAL PHYSICIAN’S KNOWLEDGE LEVEL OF PARKINSON’S DISEASE IN INDONESIA Neila Raisa; Adeliza Firzarosany Insanitaqwa; Masruroh Rahayu
MNJ (Malang Neurology Journal) Vol. 9 No. 2 (2023): July
Publisher : PERDOSSI (Perhimpunan Dokter Spesialis Saraf Indonesia Cabang Malang) - Indonesian Neurological Association Branch of Malang cooperated with Neurology Residency Program, Faculty of Medicine Brawijaya University, Malang, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.mnj.2023.009.02.10

Abstract

Background: Parkinson's disease still requires special attention considering that this condition is a progressive disease that leads to a decrease in the quality of life and life expectancy of the patient. Objective: This study aims to determine the level of understanding of general practitioners regarding Parkinson's disease and other movement disorders. Methods: We conducted a one group pretest posttest design study on 124 general practitioners who attended the World Parkinson Day Seminar. . The research instrument was a questionnaire with 20 questions, filled in by the participants independently.  Knowledge level categories are good (76-100), sufficient (56-75), and poor (<55). Results: The result of the study showed that 18% [22 respondents] had a good level of understanding, 58% [72 respondents] had sufficient knowledge, and 24% [30 respondents] had poor knowledge in terms of the pretest score. There was an increase in the average score (from 65.93 to 78.9) of the respondents after attending the seminar (p<0.05). Conclusion: This study identified that there was a significantly increased level of knowledge of Parkinson's disease symptoms after the seminar for general practitioners in Indonesia.
COMBINATION OF PATHOLOGY OF THE BRAIN AND THE OPTIC NERVE Alexandra Safonenko; Elena Ioyleva; Evgeniya Kabanova; Tatiana Seregina
MNJ (Malang Neurology Journal) Vol. 8 No. 2 (2022): July
Publisher : PERDOSSI (Perhimpunan Dokter Spesialis Saraf Indonesia Cabang Malang) - Indonesian Neurological Association Branch of Malang cooperated with Neurology Residency Program, Faculty of Medicine Brawijaya University, Malang, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.mnj.2022.008.02.15

Abstract

The relevance of assessing the lesion of the visual analyzer with optic disc drusen and the possibility of identifying concomitant pathologies, increases with the introduction of the latest diagnostic techniques.In the S. Fyodorov Eye Microsurgery Federal State Institution, Moscow, a patient, 50 years old, complaining of episodic blurred vision. The diagnosis revealed the drusen of the optic nerve head and concomitant congenital neurological pathology. The patient was consulted by a neurosurgeon with the aim of delivering a diagnosis and determining treatment tactics. The diagnosis was made: Arteriovenous malformation of the deep arteries of the sections of the left parietal lobe. After assessing the size of the arteriovenous malformation, its location in the functionally important area of the brain, it was decided to follow up the patient in dynamics. 
BIOMARKERS AND PROGNOSTIC SCORING IN CEREBRAL MALARIA Orlando Pikatan; Ellen Ferlita Tirtana; Kezia Seraphine; Wienta Diarsvitri
MNJ (Malang Neurology Journal) Vol. 8 No. 2 (2022): July
Publisher : PERDOSSI (Perhimpunan Dokter Spesialis Saraf Indonesia Cabang Malang) - Indonesian Neurological Association Branch of Malang cooperated with Neurology Residency Program, Faculty of Medicine Brawijaya University, Malang, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.mnj.2022.008.02.14

Abstract

Malaria remains a public health concern and remain the deadliest in infectious disease in the world. Cerebral malaria is a particularly severe complication of this disease and associated with high mortality. This literature review is made up from 19 literatures consisting of journals, and book. The literature review used data base www.pubmed.com, and www.scholar.google.com using “cerebral malaria and biomarker, predictor of cerebral malaria and treatment of severe malaria”. The languages for this journal are English and Indonesian. From the collection of literatures in this literature review, severe consists of cerebral malaria, blackwater fever, acute kidney injury, pulmonary edema, electrolyte disturbance, hematology disturbance, and obstetrics emergency resulting from malaria which is postpartum hemorrhage. Cerebral malaria increases the mortality of the patient, so they have to be diagnosed early and treated precisely. Patients with infection of plasmodium falciparum and GCS<11 must be suspected as cerebral malaria. Biomarker examination such as Soluble ICAM-1, Specific muscle’s protein, Angiopoetin-1 and 2, and Plasma microparticles is the most precise way to detect malarial emergency earlier Coma Acidosis Malaria score is also found to be useful in predicting the prognosis in cerebral malaria. Early diagnosis should be made as early as possible to reduce mortality from malaria and its emergencies.
INDONESIAN PEOPLE RISK FACTORS OF NOCTURIA (TWO OR MORE VOIDS PER NIGHT) OLDER THAN 40 YEARS-OLD Besut Daryanto; Athaya Febriantyo Purnomo; Taufiq Nur Budaya; Seskoati Prayitnaningsih; Nadia Artha Dewi
MNJ (Malang Neurology Journal) Vol. 8 No. 2 (2022): July
Publisher : PERDOSSI (Perhimpunan Dokter Spesialis Saraf Indonesia Cabang Malang) - Indonesian Neurological Association Branch of Malang cooperated with Neurology Residency Program, Faculty of Medicine Brawijaya University, Malang, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.mnj.2022.008.02.6

Abstract

Background: Nocturia is a common urinary system disease. Objective: This study aimed to investigate the causes of nocturia in women Indonesian inhabitants aged≥ 40 years. Methods: A stratified sample strategy was used to conduct a randomized cross-sectional study on 562 residents under the age of 40 in Malang City, East Java, Indonesia. A questionnaire was completed, which included socioeconomic demographics, lifestyle characteristics, and clinical history. Each night, nocturia was defined as at least two voids. The chi-squared test was used to determine proportional differences between age and gender groups. Multivariate logistic regression analysis was used to assess gender-related factors. This was determined that P0.05 was statistically significant. Results: Data on 562 people aged 61.60 + 9.81 years eligible for statistical analysis at the end, comprising 185 (32.92%) men and 377 (67.08%) women. Overall nocturia prevalence was 31.8% (179/562). It rose significantly with age (P<0.001) and reached >48% in those above the age of 70. In both men and women, nocturia was linked with diabetes, hypertension, cardiovascular disease, and the overactive bladder symptom score (OABSS) (P0.05). There was no link discovered between nocturia and education, profession, civil status, BMI, female birth history, or the International Prostate Symptom Score. Conclusion: Nocturia is linked to aging, cardiovascular disease, hypertension, OABSS, and diabetes in Indonesians over the age of 40.
BREAST CANCER ASSOCIATED ANTI YO-ANTIBODY MEDIATED PARANEOPLASTIC CEREBELLAR DEGENERATION: CASE SERIES AND REVIEW OF LITERATURE Sanaullah Mudassir; Ashok Kumar; Neetu Sinha; Abhay Ranjan
MNJ (Malang Neurology Journal) Vol. 8 No. 2 (2022): July
Publisher : PERDOSSI (Perhimpunan Dokter Spesialis Saraf Indonesia Cabang Malang) - Indonesian Neurological Association Branch of Malang cooperated with Neurology Residency Program, Faculty of Medicine Brawijaya University, Malang, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.mnj.2022.008.02.13

Abstract

Paraneoplastic cerebellar degeneration (PCD) is a rare immune mediated disorder characterized by progressive cerebellar ataxia in presence of onconeural antibodies which occurs due to an indirect effect of underlying malignancy i.e. small cell lung cancer (SCLC), breast and gynecologic cancer, and Hodgkin lymphoma. In about 50% of patients neurological manifestation of Paraneoplastic cerebellar degeneration occurs prior to detection of carcinoma. Anti-Yo Antibody is the commonest antibody present in patients with Paraneoplastic cerebellar degeneration which is associated with breast carcinoma. We describe 3 female patients with anti YO antibody mediated PCD with breast cancer. One patient had a previous diagnosis of breast cancer with post mastectomy status one year back. Two of them presented with ataxia and on further examination, breast lump was found. All three patients had symmetrical ataxia with one patient had severely debilitating ataxia and was not able to walk unassisted. Magnetic resonance imaging brain showed cerebellar atrophy in two patients while one patient had normal MRI. Anti- YO antibody was strongly positive in all the three patients. All patients were given immunotherapy (corticosteroids in 2, Intravenous immunoglobulin in 1) with 1 patient showed modest improvement These case highlights the need to consider for workup for paraneoplastic cerebellar degeneration in female patients presenting with subacute to chronic progressive ataxia, so that the tumors can be detected and treated in early stage with a good outcome. 
AFFECTIVE BEHAVIORAL THERAPY (ABT): FUNDAMENTAL PRACTICE IN THERAPEUTIC LISTENING AND OCCUPATIONAL THERAPY FOR PRIMARY CARE WORKERS DURING THE COVID-19 PANDEMIC Ciro Blujus Dos Santos Rohde; Márcio Fernando Da Silva; Hermano Tavares
MNJ (Malang Neurology Journal) Vol. 8 No. 2 (2022): July
Publisher : PERDOSSI (Perhimpunan Dokter Spesialis Saraf Indonesia Cabang Malang) - Indonesian Neurological Association Branch of Malang cooperated with Neurology Residency Program, Faculty of Medicine Brawijaya University, Malang, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.mnj.2022.008.02.1

Abstract

Background: COVID-19 pandemics have triggered mental health problems in various communities. Primary healthcare workers (PHCW), are at the frontline of COVID-19 crisis, having to deal with infected patients and their families. Objective: To evaluate the efficacy of Affective Behavioral Therapy (ABT) for the treatment and prevention of mental health disorders for PHCW.  Methods: PHCW from a primary care unit (PCU) were invited to participate in an ABT group. They answered the Patient Health Questionnaire-4 (PHQ-4) about how they felt before the sessions and after them. Results: 10 sessions were offered between April and June 2020 and 30 PHCW participated, 22 women and 08 men mean age was 36.8 (SD=9.7) years old. The average number of participants per session was 4.4 (SD=2.2). Pre- and post-intervention PHQ-4 scores showed significant improvement in total score (p < 0.001). Conclusion: PHCWs mental health is strategic for the management of the community during crises related to natural crises. The ABT was effective in supporting the mental health of PHCW during the COVID-19 epidemic. Future controlled studies must be conducted in order to further test its efficacy.  Keywords: COVID-19, mental health, primary care, therapeutic listening, occupational therapy, affective behavioral therapy
PROFILE OF CHARACTERISTIC, RISK FACTOR, AND STROKE SEVERITY ON INFARCTION STROKE PATIENTS Aisyah Rizki Ramadhani; Mohammad Saiful Ardhi; Subur Prajitno
MNJ (Malang Neurology Journal) Vol. 8 No. 2 (2022): July
Publisher : PERDOSSI (Perhimpunan Dokter Spesialis Saraf Indonesia Cabang Malang) - Indonesian Neurological Association Branch of Malang cooperated with Neurology Residency Program, Faculty of Medicine Brawijaya University, Malang, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.mnj.2022.008.02.7

Abstract

Background: Stroke is the second leading cause of death and the third leading cause of morbidity. Therefore, it is important to know which risk factor that most patients have. Stroke can be divided according to its severity using NIHSS, NIHSS itself has strong ability to predict outcomes after stroke Objective: This study’s aim to learn about profile of characteristic, risk factor, and stroke severity on infarction stroke patients in ward Seruni A RSUD Dr. Soetomo from July 2018 – June 2019. Methods: This descriptive observational study’s samples are patients with infarction stroke in ward Seruni A RSUD Dr. Soetomo from July 2018 – June 2019. The observed profile include age, sex, ethnic, family history of vascular disease, history of hypertension, diabetes, heart disease, dyslipidemia, obesity, smoking, alcohol consumption, physical inactivity, and stroke severity. Results: From 200 patiens, 55% (110) are 56-70 years old. 61% (122) patients are male. 81 out of 96 are Javanese. 25 out of 135 have family history of vascular disease, 140 out of 194 have hypertension, 69 out of 190 have diabetes, 27 out of 183 have heart disease, 101 out of 174 have dyslipidemia, 62 out of 162 have obesity, 33 out of 82 smoke, 4 out of 63 consume alcohol, and 50 out of 55 are inactive physically. On admission, out of 60 patients, 27 have moderate stroke, 25 minor, and 8 moderate to severe. On discharge, out of 49 patients, 23 have moderate stroke, 20 minor, 3 moderate to severe, and 3 severe. Conclusion: Infarction stroke patients were mostly male and the peak incidence occur between 56-70 years old. Most patients have histories of hypertension, dyslipidemia, and diabetes. On admission and discharge, most patients have moderate stroke, followed by mild stroke.

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