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Majalah Obstetri dan Ginekologi
Published by Universitas Airlangga
ISSN : 08540381     EISSN : 25981013     DOI : 10.20473/mog.V27I32019.90-93
Core Subject : Health,
Health Professions Medicine & Pharmacology
Majalah Obstetri & Ginekologi (MOG) or the Journal of Obstetrics & Gynecology Science is a scientific journal published by the Department of Obstetrics and Gynecology, Faculty of Medicine, Universitas Airlangga, Surabaya, Indonesia, in collaboration with the Indonesian Obstetrics and Gynecology Association (POGI) of Surabaya branch.
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Articles 7 Documents
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Search results for , issue "Vol. 24 No. 1 (2016): Januari - April" : 7 Documents clear
Keikutsertaan Kelas Ibu Hamil Berpengaruh terhadap Pengetahuan dan Sikap Ibu dalam Praktik Inisiasi Menyusu Dini Elsa Budi Sihsilya Rahmawati; R Kuntoro; Bambang Trijanto
Majalah Obstetri dan Ginekologi Vol. 24 No. 1 (2016): Januari - April
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (86.11 KB) | DOI: 10.20473/mog.V24I12016.8-12

Abstract

Strategi Pemerintah dalam menurunkan AKI dan AKB salah satunya kelas ibu hamil. Tujuan penelitian ini mengetahui pengaruh keikutsertaan ibu di  kelas ibu hamil terhadap praktik IMD pada ibu bayi usia 6-8 bulan di wilayah kerja Puskesmas Sisir Kota Batu. Penelitian ini merupakan penelitian analitik dengan desain cohort retrospektif. Populasi terbagi menjadi dua, populasi terpapar yang mengikuti kelas ibu hamil saat hamil anak terakhir dan populasi tidak terpapar  ibu yang tidak mengikuti kelas ibu hamil. Besar sampel 32 responden. Analisis data dengan uji chi square. Hasil analisis bivariat usia (p value = 0,229), pendidikan (p value = 0,1790, paritas (p value = 0,011), pengetahuan (p value = 0,047), sikap (p value = 0,893), riwayat persalinan (p value = 0,021), informasi (p value = 0,472), penolong persalinan (p value = 0,017), tempat persalinan (p value = 0,003), keikutsertaan kelas ibu hamil (p value = 0,27), pengambil keputusan (p value = 0,137), penyuluhan saat hamil (0,16) Hasil analisis menunjukkan variabel yang signifikan adalah paritas (p=0,011), pengetahuan (p=0,047), penolong persalinan (p=0,017), tempat persalinan (0,003), riwayat persalinan (p=0,021), penyuluhan saat hamil (p=0,010). Kesimpulan penelitian ini tidak ada pengaruh keikutsertaan ibu di kelas ibu hamil terhadap praktik IMD, akan tetapi kelas ibu hamil berpengaruh terhadap pengetahuan dan sikap ibu. Pengetahuan berpengaruh terhadap praktik IMD.
Penurunan progesterone-induced blocking factor (PIBF) sebagai penanda preeklampsia Achmad Salman; Budi Wicaksono; Erry Gumilar Dachlan; Widjiati Widjiati
Majalah Obstetri dan Ginekologi Vol. 24 No. 1 (2016): Januari - April
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (94.819 KB) | DOI: 10.20473/mog.V24I12016.13-18

Abstract

Background: Pathogenesis of preeclampsia still a controversial research objects. Progesterone induced blocking factor has protective effects in pregnancy.Objectives: To compare PIBF serum level and placental weight and investigate correlation between both in preeclampsia.Methods: This experimental study used 16 Mus musculus with normal pregnancy and 16 Mus musculus that were injected with anti Qa-2 to create a preeclampsia model. Terminations of were performed in day 16th, followed by ELISA examination for PIBF serum level and placental weight measurement.Result: PIBF serum level significantly reduced on preeclampsia model  compared with control (33,21±29,36 ng/ml vs 105,76±59,69 ng/ml; p<0,05). There was no different of placental weight in preeclampsia model compared with control (97,75±50,74 mg vs 116,09±44,45 mg; p>0,05). There was no significant correlation between PIBF serum level and placental weight.Conclusion: Decreased of PIBF serum level could be used as a marker of preeclampsia. Decreased of PIBF serum level may be correlate with placental pathology in preeclampsia.
Pengaruh Monoklonal Antibodi Bovine Zona Pelusida 3 (bZP3) terhadap Diameter dan Atresia Folikel Ovarium Mencit (Mus musculus) Annisa Trissatharra; Sri Ratna Dwiningsih; Ratna Sofaria Munir
Majalah Obstetri dan Ginekologi Vol. 24 No. 1 (2016): Januari - April
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (223.533 KB) | DOI: 10.20473/mog.V24I12016.37-42

Abstract

Objectives: To identify the effect of monoclonal antibody bZP3 at ovarian follicles that undergo atresia and diameter of various ovarian follicles.Materials and Methods: This is a true experimental research with post only control group design. Samples were 36 female mices (Mus musculus) which is divided into 6 groups, there are 3 control groups (group 1, 2, and 3) injected by Phospatase Buffer Saline (PBS) 50µl and 3 treatment groups (group 4, 5, and 6) injected by Mab bZP3 50µl. Group 1 and 4 terminated at 5th day, group 2 and 5 terminated at 10th day, and group 3 and 6 terminated at 20th day. Evaluation of atretic ovarian follicles and diameter of ovarian follicles performed by hematoxylin eosin (HE) and the data processed by parametric statistic.Results: There are no significant in different among groups in the aspect of atretic follicles and diameter of folicles (p>0.05), but descriptively, number of follicles undergo atresia of the follicle primary, secondary, and tertiary treatment group was higher than the control group, except on the 20th day of observation time.Conclusion: administration of Mab bZP3 had no effect to amount of atretic follicles and diameter of folicles during observation time.
VEGF 121 Rekombinan Dapat Memperbaiki Endoteliosis Gromerular pada Mencit Bunting Model Preeeklampsia Sri Sulistyowati; Donny Irawan; Eric Edwin; Soetrisno Soetrisno
Majalah Obstetri dan Ginekologi Vol. 24 No. 1 (2016): Januari - April
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (149.176 KB) | DOI: 10.20473/mog.V24I12016.19-24

Abstract

Preeklampsia masih merupakan penyebab utama morbiditas dan mortalitas maternal maupun perinatal. Pada preeklampsia terjadi gangguan ginjal berupa endoteliosis glomerular. Ketidakseimbangan faktor proangiogenik VEGF dan antiangiogenik sFlt-1 diduga terlibat dalam patogenesis preeklampsia. Pemberian VEGF 121 rekombinan memiliki kemampuan untuk memperbaiki fungsi endotel sehingga dapat memperbaiki endoteliosis glomerular. Penelitian ini bertujuan untuk membuktikan pengaruh VEGF 121 rekombinan terhadap perbaikan endoteliosis glomerular pada mencit model preeklampsia menggunakan metode eksperimental analitik dengan RCT, yang dilakukan pada bulan Januari – Mei 2015 di Kandang Hewan Percobaan dan Laboratorium Biomedik Fakultas Kedokteran Hewan Universitas Airlangga. Sampel dari replikasi Steel dan Torrie adalah 30 mencit bunting yang terbagi dalam 3 kelompok yaitu 10 mencit bunting normal, 10 mencit bunting model preeklampsia dan 10 mencit bunting model preeklampsia dengan terapi VEGF 121 rekombinan. Semua sampel dilakukan pemeriksaan pada endotel ginjalnya dengan metode imunohistokimia. Parameter endoteliosis glomerular menggunakan kriteria Stillman (2007) dan Wide-Swensson (2007). Analisa data menggunakan uji Kruskal Wallis dan Mann Whitney. Rerata endoteliosis gromeruler pada mencit bunting normal 1,60 dan mencit bunting model preeklampsia 1,90 dengan nilai p=0,28 (p>0,05). Rerata endoteliosis gromeruler pada mencit bunting model preeklampsia 1,90 dan mencit bunting model preeklampsia dengan terapi VEGF rekombinan 121 adalah 1,30 dengan nilai p=0,02 (p<0,05). Rerata endoteliosis gromeruler pada mencit bunting normal 1,60 dan mencit bunting model preeklampsia dengan terapi VEGF rekombinan 121 adalah 1,30 dengan nilai p=0,28 (p>0,05). Simpulan, VEGF 121 rekombinan dapat memperbaiki endoteliosis gromerular pada mencit bunting model preeeklampsia.
Aspirin Dosis Rendah Efektif Menurunan Resistensi Arteri Uterina yang Abnormal pada Ibu Hamil Usia Kehamilan 16-24 Minggu Rachmi Rachmi; Agus Sulistyono
Majalah Obstetri dan Ginekologi Vol. 24 No. 1 (2016): Januari - April
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (99.16 KB) | DOI: 10.20473/mog.V24I12016.25-30

Abstract

Objectives: To measure the thickness of elastin fibres on vaginal wall of patients with POP anterior and then analyse the correlation of this measurement with the degree of POP anterior.Materials and Methods: This research is an observational analytic study. Data collection was conducted with a cross sectional approach on 28 blocks paraffin of vaginal wall taken from POP anterior patients of whom went through an operation in Dr. Soetomo Hospital of Surabaya. Data was divided into four groups: degree 0/I , II, III and IV respectively (n = 7). Immunohistochemical staining was performed with antibodies elastin. Afterward, the thickness of the elastin fibres was measured by utilizing a microscope with a Leica Application Suite (LAS) software.Results: We found significant differences in the mean of thickness of elastin fibres in each group of patients with degrees of anterior POP 0/I , II , III and IV respectively 0,81 + 0,14 µm; 1,63 + 0,19 µm; 2,47 + 0,26µm and 3,19 + 0,36 µm (p < 0,0001 ). Based on Pearson correlation test, the results shows a correlation coefficient r = 0.965 (p < 0,0001).Conclusion: The thickness of elastin fibre on vaginal wall increased as the degree of POP anterior arise. Increased in the thickness of elastin fibers on the vaginal walls was the result from extracellular matriks remodelling on vaginal wall of anterior POP patient.
Jahe mengurangi jumlah koloni uropathogenic Escherichia coli pada wanita menopause dengan infeksi saluran kemih asimtomatis Dony Rosmana; Gatut Hardianto; Kartuti Debora MS
Majalah Obstetri dan Ginekologi Vol. 24 No. 1 (2016): Januari - April
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (105.852 KB) | DOI: 10.20473/mog.V24I12016.1-7

Abstract

Objective: To prove the effect of ginger in the UropathogenicEscerichia coli Colonies in menopausal women.Materials and Methods: A pra-experimental study with onegroup pre test-post test design. Ginger with a similar variety andage is turned into a powder capsule. The subject of the research ispatient in the geriatric and menopause outpatient clinicDr.Soetomo Central Hospital-Surabaya. Each subject taken gingerpowder for five days in row. Midstream clean catch urine wasperformed before and after the treatment in order to identify andcount the colony of Uropathogenic Escerichia coli.Results: 12 out of 52 participants had a positive UropathogenicEscerichia coli result from the culture before treatment. 5 subjectshad colony count 105cfu/ml and 7 subjects <10cfu/ml. 11subject shows a negative result and 1 subject still had a positiveresult although a number of colony is decrease cfu/mlbecome 2x103cfu/ml Tujuan: Membuktikan pengaruh jahe terhadap jumlah koloniuropathogenic Escerichia coli pada kultur urin dari wanitamenopause dengan infeksi saluran kemih asimtomatis.Bahan dan Metode: Penelitian pra-eksperimental one grouppretest-posttest design. Jahe dengan jenis dan usia panen samadiolah menjadi kapsul serbuk jahe. Subyek penelitian diperoleh dipoli Geriatri dan Menopause RSUD.Dr.Soetomo Surabaya. Setiapsubyek diberikan kapsul serbuk jahe selam 5 hari. Dilakukankultur urin tampung porsi tengah untuk identifikasi dan hitungjumlah koloni sebelum dan sesudah perlakuan.Hasil: Dari 52 partisipan, didapatkan 12 subyek dengan hasilidentifikasi dan hitung koloni kultur sebelum perlakuan yangpositif uropathogenic Escerichia coli, 5 subyek dengan hitungkoloni ≥ 105cfu/ml dan 7 subyek <105cfu/ml. Didapatkan 11subyek dengan hasil hitung koloni kultur ulangan steril dan 1subyek dengan hasil hitung koloni kultur ulangan tetap positifdengan jumlah koloni menurun 4cfu/ml menjadi 2x10cfu/ml3
Peningkatan Ketebalan Serat Elastin Dinding Vagina pada Prolapsus Organ Pelvis Anterior Achmad Zaki; Eighty Mardian; Sjahjenny Mustokoweni
Majalah Obstetri dan Ginekologi Vol. 24 No. 1 (2016): Januari - April
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (166.658 KB) | DOI: 10.20473/mog.V24I12016.31-36

Abstract

Objectives: To measure the thickness of elastin fibres on vaginal wall of patients with POP anterior and then analyse the correlation of this measurement with the degree of POP anterior.Materials and Methods: This research is an observational analytic study. Data collection was conducted with a cross sectional approach on 28 blocks paraffin of vaginal wall taken from POP anterior patients of whom went through an operation in Dr. Soetomo Hospital of Surabaya. Data was divided into four groups: degree 0/I , II, III and IV respectively (n = 7). Immunohistochemical staining was performed with antibodies elastin. Afterward, the thickness of the elastin fibres was measured by utilizing a microscope with a Leica Application Suite (LAS) software.Results: We found significant differences in the mean of thickness of elastin fibres in each group of patients with degrees of anterior POP 0/I , II , III and IV respectively 0,81 + 0,14 µm; 1,63 + 0,19 µm; 2,47 + 0,26µm and 3,19 + 0,36 µm (p < 0,0001 ). Based on Pearson correlation test, the results shows a correlation coefficient r = 0.965 (p < 0,0001).Conclusion: The thickness of elastin fibre on vaginal wall increased as the degree of POP anterior arise. Increased in the thickness of elastin fibers on the vaginal walls was the result from extracellular matriks remodelling on vaginal wall of anterior POP patient.

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