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INDONESIA
Indonesia Chimica Acta
Published by Universitas Hasanuddin
ISSN : 2085014X     EISSN : 26556049     DOI : -
Core Subject : Engineering,
Jurnal Akta Kimia Indonesia (Indonesia Chimica Acta) is a peer-reviewed research journal that is devoted to the dissemination of new and original knowledge in all branches of chemistry. The result of research and development in the fields of chemistry in both experimental and theory/ computation, chemical-based technological innovations, and chemical applications in industrial fields. The journal publishes original research articles or review articles in organic chemistry, inorganic chemistry, analytical chemistry, physical chemistry, biochemistry, and environmental chemistry.
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Articles 142 Documents
Anti-free radical activity test of endophytic fungal fermentate extract on the Snake Plants (Sansevieria trifasciata Hort. Ex Prain) using the TLC-Autography method Seniwati; Rusli; Adelia Fitrah; Tadjuddin Naid
Jurnal Akta Kimia Indonesia (Indonesia Chimica Acta) Volume 14, No 2: December 2021
Publisher : Hasanuddin University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20956/ica.v14i3.14496

Abstract

Degenerative diseases occur due to damage to cells, fat tissue, and the immune system caused by several factors. One theory that causes degenerative diseases is the presence of free radicals. The Snake plant is one of the plants in Indonesia that has long been known as a plant that is useful as anti-free radicals. The research was conducted by isolating and purifying endophytic fungi and determining the autogram profile of free antiradical activity from The Snake plant. From the purification results obtained 7 isolates, followed by macroscopic examination and fermentation of each isolate. The results of the screening test showed that 2 fermentates were active as anti-free radicals, namely AF 1 and AF 3. Fermentate isolates AF 1 and AF 3 were identified by TLC-autography using a mixture of n-hexane: ethyl acetate (7:1). TLC-autography test results by spraying DPPH isolates AF 1 and isolates AF 3 showed yellow spots on a purple background with Rf1 values ​​of 0.90 and Rf2 of 0.2 in AF1 isolates and Rf1 values ​​of 0.83 and Rf2 of 0.16 on AF3 isolates. potential as anti-free radicals. From the results of this study, it was concluded that there was anti-free radical activity in the Snake plant.
Effects of tobacco cultivation on chemical properties of agricultural soils Mir Md. Mozammal Hoque; Md. Moshiuzzaman Khan; Tarmina Akter Mukta; Muliadi Muliadi; Shamim Al Mamun
Jurnal Akta Kimia Indonesia (Indonesia Chimica Acta) Volume 14, No 2: December 2021
Publisher : Hasanuddin University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20956/ica.v14i3.17969

Abstract

Tobacco is grown intensively in the North Western region of Bangladesh. The farmers in that region in Bangladesh receive less production of the next crop of tobacco and experience economical loss. We aimed to determine the impact of tobacco cultivation in soils. In order to determine the impact of tobacco cultivation in soil, 20 soil samples (10 from tobacco cultivated land and 10 from non-tobacco cultivated land) were collected from the study area. The samples were analyzed for soil pH, organic matter, humidity, macronutrients (N, P, K, S, Ca and Mg) and micronutrients (Zn, Fe, Mn, Cu and B). The concentration of available phosphorus (23.22 µg/g), total nitrogen (0.084 %), calcium (798 µg/g), magnesium (438 µg/g), zinc (1.00 µg/g), manganese (1.70 µg/g) boron (0.17 µg/g) including soil pH, organic matter and humidity showed higher values in tobacco cultivated land than those of the non-tobacco cultivated land. In contrast, concentration of total potassium (148.2 µg/g), available sulfur (5.45 µg/g), copper (2.40 µg/g) and iron (10.82 µg/g) in tobacco land showed lower values than those of the non-tobacco land. Soil magnesium level increased with increasing pH although the potassium level decreased with the increase of pH of the tobacco cultivated soils.
Performance Analysis of biosorption of Heavy Metal and Biodegradation PAH of Isolates Marine Sponges Symbiont Bacteria Ismail Marzuki; Andi Muhammad Asdar Marzuki; Hardimas Hardimas
Jurnal Akta Kimia Indonesia (Indonesia Chimica Acta) Volume 14, No 2: December 2021
Publisher : Hasanuddin University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20956/ica.v14i3.18333

Abstract

Heavy metal pollutants and polycyclic aromatic hydrocarbon contaminants, also known as PAHs, need attention from related parties, considering that their use is very wide, as well as their relatively high natural releases. Careless and uncontrolled handling has the potential to cause problems for creatures, especially in marine ecosystems. The aim of the study was to determine the performance of marine sponge microsymbiont isolates in heavy metal biosorption and PAH biodegradation. The method applied, pure isolates of marine sponge symbionts were cultured on NA media. The suspension of isolates was made using physiological 0.9 % NaCl solution. Suspension adapted 24 hours. The isolate suspension was interacted with heavy metals Cd2+ and As3+, each with a concentration of 100 ppm and naphthalene and anthracene with a concentration of 1000 ppm. Interaction time of 5, 10, 15, and 20 days. Results of the analysis showed the biosorption capacity of the bacterial isolate Sp6.B2 to Cd2+ = 83.190 %, while Sp8.B1 = 82.240 %. Biosorption performance of Sp6.B2 isolates against As3+ = 99.890 %, while Sp8.B1 = 99.894 %. The biodegradation performance of Sp6.B2 isolates had a higher aggressiveness towards naphthalene and anthracene test contaminants than Sp8.B1 isolates. These results indicate that the biosorption performance of Sp6.B2 ˃ Sp8.B1 isolates against Cd2+ contaminants and vice versa Sp6.B2 ˂ Sp8.B1 against As3+ biosorption, while the biodegradation performance of Sp6.B2 ˃ Sp8.B1 isolates both against naphthalene and anthracene test contaminants
Chemical Properties of Fish Gelatin from Skin and Bone of Yellowfin Tuna (Thunnus Albacares) Syadza Firdausiah; Nur Madya; Seniwati; Meidistria Tandi Rapak
Jurnal Akta Kimia Indonesia (Indonesia Chimica Acta) Volume 14, No 2: December 2021
Publisher : Hasanuddin University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20956/ica.v14i3.18397

Abstract

This study aims to extract and compare the chemical properties of gelatin from the skin and bone of yellowfin tuna (Thunnus albacares) by using the acid method. The proximate and FTIR analyses of tuna skin and bone gelatin (TSG and TBG) were conducted to determine their chemical properties. The acid condition successfully produced gelatin, which is 3.24% of TSG and 2.61% of TBG yields. The proximate properties revealed that both extracted gelatin BEG and CG fulfil the Indonesian standard quality of gelatin, with a high level of total protein and low lipid content. Amide A, I, II, and III were shown at 3452.58, 1637.56, 1517.98, and 1240.23 cm-1 respectively in TSG FTIR spectra, and at 3493.09, 1660.71, 1533.41, and 1238.30 cm-1, respectively in TBG spectra. Both skin and bone of yellowfin tuna can potentially be used in the production of gelatin for industrial and pharmaceutical purposes with further optimation.
Voltammetric Detection of Uric Acid at Screen Printed Electrode: A Review Wulan Tri Wahyuni; Dyah Iswantini Pradono; Selvitia Ulandari
Jurnal Akta Kimia Indonesia (Indonesia Chimica Acta) Volume 14, No 2: December 2021
Publisher : Hasanuddin University

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Uric acid is a compound produced from purine metabolism. The excess amount of these compounds could causes diseases in the body. Effective and practical methods are needed for early detection of uric acid. Technically, uric acid could be detected using enzymes (enzymatic) and without enzymes (non-enzymatic). Several methods have already reported for uric acid detection in biological samples, including fluorimetry, colorimetry, liquid chromatography, flow injection analysis, chemiluninescence, and electrochemical detection. Among electrochemical detection methods, voltammetry is one of the most prospective for uric acid detection. This review covers the approach of uric acid detection including enzymatic and nonenzymatic approach, several voltametric technique for uric acid detection, and screen printed and modified electrode as platform for uric acid detection. Analytical performance such as linear range, sensitivity, selectivity and reproducibility of uric acid detection using various voltametric method and at different platform were also highlighted.
Terpenoid Compounds of Lime (Citrus Aurantifolia) Peel by Using Gas Chromatography Mass Spectrometry (GCMS) Method mirnawati mirna
Jurnal Akta Kimia Indonesia (Indonesia Chimica Acta) Volume 14, No 2: December 2021
Publisher : Hasanuddin University

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Terpenoid compounds known as essential oils can be used as flavour enhancers and medicinal sources. The Citrus genus is a citrus aurantifolia species. Citrus aurantifolia (Rutaceae) is a fruit type most often consumed by the public. This study aimed to determine the terpenoid compounds contained in lime peel extract (C. aurantifolia). This study used the extraction method for 3 x 24 hours and then continued by using a sonicator. The viscous extract was then analyzed by using a GCMS method. This study obtained that the β-pinene compound for the retention time was 7.92, and the per cent area was 34.81 %. While for the D-limonene compound for the retention time was 6.62, and the per cent area was 20.15 %
Kinetics and Adsorption of Molecularly Imprinted Polymers Dibutylphthalate St Fauziah; Fausan Sullahi; Nunuk Soekamto; Paulina Taba
Jurnal Akta Kimia Indonesia (Indonesia Chimica Acta) Volume 14, No 2: December 2021
Publisher : Hasanuddin University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20956/ica.v14i3.18588

Abstract

Molecularly Imprinted Polymers (MIP) are polymers with active sites that can recognize target molecules selectively. This study aims to determine the kinetics and adsorption capacity of MIP_DBP. The method used in the synthesis of MIP_DBP was precipitation polymerization using methacrylic acid (MAA) monomer, Ethyleneglycol Dimethacrylate (EGDMA) cross linker, DBP as a template molecule, and toluene as a solvent. The MIP_DBP obtained is a white solid. The results of the MIP_DBP adsorption kinetics test followed the pseudo-second-order kinetics model and the adsorption capacity according to the Freundlich isothermal adsorption model with the adsorption capacity value for DBP was 9.38 mg/g.
Optimization and Validation of Electrochemical Biosensor Based on Pseudomonas sp. Biofilm Immobilized on Screen-Printed Carbon Electrode in Detecting Benzene Alfiah Alif; Dyah Iswantini; Henny Purwaningsih; Novik Nurhidayat; Ali Aulia Ghozali; Amalyah Febryanti
Jurnal Akta Kimia Indonesia (Indonesia Chimica Acta) Volume 15, No 1: June 2022
Publisher : Hasanuddin University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20956/ica.v15i1.19008

Abstract

Benzene is known as one of the hazardous compounds potentially interfering the health and polluting the environment. Generally, detecting benzene still requires a long analysis time and expensive costs. Therefore, this study aimed to evaluate the analytical performance of a biosensor with microbes as the biodetection element. Pseudomonas sp. biofilms which produce benzene dioxygenase enzyme and then immobilized on a Screen-Printed Carbon Electrode (SPCE). The results of the optimization of the biosensor obtained a benzene concentration of 3 mM, a bacterial density of 1.4x1011 cells/mL and suspension pH of 7.5. The optimization results are used to measure the analytical performance of the biosensor. The value of analytical performance produced on linearity is in the measurement range of 0.1 - 3 mM, the equation y = 7.4118x + 80.048 with R2 = 0.9744. The detection limit and quantity limit are 0.5630 mM and 1.8767 mM respectively, with a sensitivity of 7.4188 μA/mM. The precision obtained shows that the SPCE biofilm method has moderate accuracy with a %SBR value below 5%. The selectivity of this method still needs to increase, but the stability of the benzene biosensor increases up to 35 days with an activity of 100.36%. This indicates the immobilization of Pseudomonas sp. had potency as an alternative method for detecting benzene and it can be developed for a prototype.
ISM Identification and Distribution of Polycyclic Aromatic Hydrocarbon Pollutants in Coastal Ecosystem the Marine Tourism Area, South Sulawesi Ismail Marzuki; Nur Rahmi Putri Lubis; Irham Pratama; Noviar Nurdin Kasim
Jurnal Akta Kimia Indonesia (Indonesia Chimica Acta) Volume 15, No 1: June 2022
Publisher : Hasanuddin University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20956/ica.v15i1.20898

Abstract

Today's marine tourism is experiencing rapid growth to meet the global needs of the world's population. Exploitation of marine biological wealth is no less important because it involves human life. The marine ecosystem must be of high quality and free from exposure to toxic pollutants, such as PAHs. The marine ecosystem must be of high quality and free from exposure to toxic pollutants, such as PAHs, microplastics. This research aims to provide data and information about the types and abundance of aromatic hydrocarbon compounds in sediments, sea water and marine biota around KKI waters. The analytical method to meet these objectives uses GS/MS. The status of marine tourism areas, especially around KKI waters, is declared polluted by PAHs. The types of PAHs identified in each sample at the three sampling stations were dominated by naphthalene (NL), phenanthrene (PT), pyrene (PR) and azulene (AZ). The average total abundance of PAHs in sponge samples (±70.51%), sediments (±67.30%), followed by seawater samples (±64.85%), starfish samples (±41.80%) and fish (±26.74%). The NL type PAHs were found in all types of samples and at all stations, where the PAHs were thought to originate from industrial, hospital, and household activities. The status of marine tourism, especially around the KKI waters, for tourists needs to be careful and alert, because the KKI area is not completely free from harmful and toxic pollutants, so it is a risk to health. Makassar City TMA managers are encouraged to make efforts to reduce the rate of increase in the concentration of regional PAHs, such as providing periodic data and information about harmful pollutants, education for every tourist to care about waste and planting coastal plants such as mangroves which have a biofilter function against toxic pollutants.
Pharmacology Analysis of The Active Compound of Makassar Fruit (Brucea Javanica) as Antidiabetic Via Bioinformatics Approach Arwansyah Arwansyah; Vivi Dia A Sangkota; Dewi Satria Ahmar; Magfirah Magfirah; Karina Nadya Sirajuddin; Adwi Restafara; Abdur Rahman Arif
Jurnal Akta Kimia Indonesia (Indonesia Chimica Acta) Volume 15, No 2: December 2022
Publisher : Hasanuddin University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20956/ica.v15i2.21043

Abstract

Diabetes is one of the emergency diseases worldwide due to the large case each year. Therefore, searching the potential treatment become crucial to treating the disease. In this research, homology modeling and molecular docking were employed to analyze the active compounds of Makassar fruit (Brucea javanica) as antidiabetic. Alpha glucosidase (AG) is used as a target, and the ligands are javanicin and javanicisode B, both active molecules of Brucea javanica. According to molecular docking results, all ligands have the potential to bind to the receptor because of their negative energy scores. Also, javanicin has higher binding energy (-8.0 kcal/mol) than the control (-5.7 kcal/mol). Furthermore, hydrogen bonds and hydrophobic interactions allow these two active chemicals to attach to an important location on AG. Thus, our finding implied that two active compounds of Brucea Javanica could be inhibitors for the receptor, and javanicin may become a promising drug against diabetes.

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