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All Journal Health Science Journal of Indonesia Damianus Journal of Medicine Indonesian Journal of Tropical and Infectious Disease The Indonesian Biomedical Journal Journal of the Indonesian Medical Association : Majalah Kedokteran Indonesia Cermin Dunia Kedokteran Jurnal Kedokteran Meditek Indonesian Journal of Pharmacology and Therapy
Lucky Hartati Moehario
Departemen Mikrobiologi, Fakultas Kedokteran Dan Ilmu Kesehatan, Universitas Katolik Indonesia Atma Jaya, Jakarta, Indonesia
Biochemistry, Genetics & Molecular Biology Dentistry Earth & Planetary Sciences Education Health Professions Immunology & microbiology Medicine & Pharmacology Neuroscience Nursing Public Health

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Infeksi Luka Operasi (ILO) di Bangsal Kebidanan dan Kandungan RSUPN Ciptomangunkusumo (RSCM): Laporan Serial Kasus Bulan Agustus-Oktober 2011 Wardoyo, Eustachius Hagni; Tjoa, Enty; Ocvyanty, Dwiana; H Moehario, Lucky
Cermin Dunia Kedokteran Vol 41, No 5 (2014): Muskuloskeletal
Publisher : PT. Kalbe Farma Tbk.

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (567.969 KB) | DOI: 10.55175/cdk.v41i5.1135

Abstract

Tujuan: Mendeskripsikan kejadian Infeksi Luka Operasi (ILO) di bangsal Kebidanan dan Kandungan RSCM selama bulan Agustus- September 2011. Metode: Deskripsi analitik terhadap data rekam medik di bagian Kebidanan dan Kandungan RSCM dengan cara purposive sampling. Kejadian ILO yang dilaporkan oleh tim pengendalian infeksi rumah sakit (PPIRS) dimasukkan sebagai kriteria inklusi. Hasil: Infeksi Luka Operasi (ILO) di Bangsal Kebidanan dan Kandungan RSCM selama Agustus-Oktober 2011 memiliki insidensi 25/566 (4,4%). Mikroorganisme penyebab ILO: E. coli (7), Acinetobacter spp. (2), Staphylococcus epidermidis (2), Pseudomonas spp., Enterobacter aerogenes, Klebsiella oxytoca, Klebsiella pneumonia, Staphylococcus aureus, Streptococcus non hemolitikus, grup D masing-masing 1, Staphylococcus sp. & Bacillus sp. (1), Klebsiella pneumonia & Pseudomonas sp. (1) dan E.coli & Acinetobacter sp (1). Simpulan: Insidensi ILO bangsal Kebidanan dan Kandungan pada Agustus – Oktober 2011 dilaporkan 4,4%. E. coli merupakan organisme penyebab ILO terbanyak.Objective: To describe the incidence of surgical site infection (SSI) in Obstetric and Gynaecologic Ward Cipto Mangunkusumo National Referral Hospital (RSCM) during August to September 2011. Method: Analytic description on medical record from Obstetric and Gynaecologic Ward obtained by purposive sampling methods. The incident of SSI reported by RSCM infection control team was included. Result: The incidence of SSI during August to September 2011 was 25/566 (4,4%). The organism detected were: E. coli (7), Acinetobacter spp. (2), Staphylococcus epidermidis (2), Pseudomonas spp., Enterobacter aerogenes, Klebsiella oxytoca, Klebsiella pneumonia, Staphylococcus aureus, Streptococcus non hemolitikus, grup D one case each, Staphylococcus sp. & Bacillus sp. (1), Klebsiella pneumonia & Pseudomonas sp. (1) dan E.coli & Acinetobacter sp (1). Conclusion: The incidence of SSI in Obstetric and Gynaecologic ward during August to September 2011 was 4.4%. E. coli was the organism most frequently isolated.
POLA KUMAN DAN FAKTOR RISIKO PADA PASIEN ABSES LEHER DALAM DI RUMAH SAKIT ATMA JAYA Kendrick Klaudius Hartedja; Ricky Yue; Lucky H. Moehario
Bahasa Indonesia Vol 20 No 1 (2021): Damianus Journal of Medicine
Publisher : Atma Jaya Catholic University of Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25170/djm.v20i1.1734

Abstract

Introduction: Deep neck abscess is a pus accumulation in the space and tissue of the cervical fascia caused by an infection and has the potential for several complications. Appropriate use of antibiotics can prevent these complications, but long culture time has been a main concern. Diabetes and oral hygiene are identified as commonly found risk factors for deep neck abscess. This study aims to analyze patients’ characteristics and the usage of antibiotics in treating deep neck abscess patients in Atma Jaya Hospital as well as assessing the effect of diabetes and oral hygiene as the causes for deep neck abscess. Methods: This was a cohort retrospective, descriptive analytic study. The samples were from 23 deep neck abscess patients undergoing treatment in Atma Jaya Hospital and met the inclusion and exclusion criteria. Chi square and Fisher exact test were used to determine the significance effect of diabetes and higiene oral in relation to deep neck abscess. Results: There were more male patients than female patients with age range 20-30 years old. Streptococcus viridans and Streptococcus pyogenes were the most common bacteria causing deep neck abscesses. Metronidazole, gentamicin and ceftriaxone were the most widely used antibiotics and it had shown great compatibility to fight against germs found in this disease. Statistical test results on the effect of oral hygiene oral to submandibular abscesses, peritonsillar, and Ludwig’s angina were p(AS)=0.605, p(AP)=1.000, and p(LA)=1.000, while of diabetes were p(AS)=0.685, p(AP)=0.657, and p(LA)=1.000. Conclusion: Deep neck abscess tends to occur in male patients of productive age. Metronidazole, gentamicin and ceftriaxone were the recommended empiric antibiotics. There was no significant relationship between oral hygiene and diabetes on the occurrence of deep neck abscesses.
EFEKTIVITAS EKSTRAK ETANOL DAUN TEH CAMELLIA SINENSIS 50% SEBAGAI ANTISEPTIK TANGAN Monica Oktaviana; Johannes C Prihadi; Lucky H. Moehario
Bahasa Indonesia Vol 20 No 1 (2021): Damianus Journal of Medicine
Publisher : Atma Jaya Catholic University of Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25170/djm.v20i1.1835

Abstract

Introduction: : Practicing hand hygiene is a way to control an infection. The recent COVID-19 pandemic, hand hygiene has become the necessity. Using antiseptic which contain chemical active ingredients causes skin problem. Camellia sinensis is a natural ingredient which its antimicrobial properties is due to the presence of catechin. The study was aimed to determine the effectivity of ethanol extract of Camellia sinensis tea leaves as hand antiseptic. Methods: This research was a comparative experimental analytic to 32 respondents conducted in the Microbiology Laboraroty of Faculty Medicine and Health Sciences–Atma Jaya Jakarta Catholic University of Indonesia. Sampling was carried out by taking bacterial swabs on the right palms. Followed by dilution using serial dilution method and inoculated onto nutrient agar using the spread plate technic. After incubation at 37oC overnight the bacterial colonies were calculated using colony counter within a range of 30-300 colonies per plate. Wilcoxon and Mann-Whitney was used for data analysis. Results: The total number of bacterial colonies after sanitizing using 50% ethanol extract of Camellia sinensis tea leaves was reduced by 55.04% (p=0.003). Meanwhile, 70% alcohol curb the bacterial colonies by 76.84% (p=0.000). The comparison of the effectivity of 50% ethanol extract of Camellia sinensistea leaves versus 70% alcohol as hand antiseptic was insignificance (p=0.300). Conclusion: 50% ethanol extract of Camellia sinensis tea leaves showed activity against hand’s microorganisms. However, the percentages of Camellia sinensis extract might be increased so as to achieve the effectivity of 70% alcohol.
Screening of Legionella pneumophila from water sources in the hospitals in Jakarta Lucky Moehario; T. Robertus; Yuliana Grace; Enty Tjoa
Health Science Journal of Indonesia Vol 10 No 1 (2019)
Publisher : Sekretariat Badan Penelitian dan Pengembangan Kesehatan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22435/hsji.v10i1.1852

Abstract

Latar belakang: Pneumonia akibat bakteri Legionella masih menjadi masalah di berbagai tempat di dunia; menjadi penyebab 2-15 % dari pneumonia yang perlu di rawat di Rumah Sakit. Kasus legionellosis di Indonesia dilaporkan terjadi di Bali pada tahun 1996 dan di Tangerang tahun 1999. Keberadaan Legionella di fasilitas Pelayanan Kesehatan berpotensi sebagai penyebab infeksi nosokomial. Bakteri Legionella hidup di lingkungan perairan hangat dan lembab, juga ditemukan diberbagai sumber air seperti, sumber air sistem pendingin ruangan, kolam renang, tempat penampungan air di rumah sakit, perkantoran, hotel, dan perumahan sehingga turut berkontribusi dalam terjadinya community acquired dan pneumonia nosokomial. Metode: Penelitian ini merupakan penelitian deskriptif yang bertujuan untuk penapisan keberadaan Legionella pneumophila diberbagai sumber dan penampungan air di Rumah Sakit (RS) di Jakarta dengan menggunakan medium Legionella Charcoal Yeast Extract (CYE) dan dengan berbagai suplemen. Tujuh belas sampel air yang berasal dari berbagai sumber air di dua RS yang berlokasi diJakarta Utara dan Barat telah diteliti. Hasil: Dua puluh satu koloni yang ditemukan memiliki karakterisitik L. pneumophila dari semua varian medium, namun pada tes agglutinasi latex tidak memberikan reaksi positif. Kesimpulan: L. pneumophila tidak ditemukan diberbagai sumber air dari dua RS ini. Penggunaan metode yang lebih sensitif dan spesifik perlu dilakukan untuk memastikan ditemukannya L. pneumophila. Kata kunci: Legionellosis, Legionella pneumophila, medium BCYE Abstract Background: Pneumonia due to Legionella bacteria is still a problem in various places in the world, causes 2 15% of pneumonia that need hospitalization. In Indonesia, legionellosis cases have been reported in Bali in 1996 and Tangerang in 1999. The existence of Legionella in healthcare facilities is potential to cause nosocomial infections. Legionella bacteria live in warm and humid waters, and are also commonly found in various water sources, such as water cooling systems, swimming pools, water reservoirs in hospitals, offices, hotels and housing. These bacteria contribute to the occurrence of community-acquired and nosocomial pneumonia. Methods: This study was a descriptive research, and aimed to screen water sources and reservoirs in the hospitals in Jakarta for the existence of Legionella pneumophilla using Legionella Charcoal Yeast Extract (CYE) medium with various supplements. A total of 17 water samples from 2 hospitals located in West and North Jakarta have been examined. Results: The results showed a total of 21 colonies with characteristics as of L. pneumophila were obtained from those water samples, however, none showed positive results in the latex agglutination test. Conclusion: L. pneumophila was not found thus far in the water sources in these two hospitals. A more sensitive and specific approaches might be used to enable the findings of L. pneumophila. Keywords: Legionellosis, Legionella pneumophila, BCYE medium
Comparison of BCYE and BMPA media on recovery rate of Legionella pneumophila Lucky Moehario; Enty Tjoa; Mutiara J. Taslim; Yohanna Angelina
Health Science Journal of Indonesia Vol 11 No 1 (2020)
Publisher : Sekretariat Badan Penelitian dan Pengembangan Kesehatan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22435/hsji.v11i1.3127

Abstract

Latar belakang: Legionella pneumophila (L. pneumophila) telah banyak diketahui sebagai penyebab legionellosis; habitat nya di berbagai sumber air, lingkungan lembab dan hangat. Metode kultur menggunakan media spesifik masih menjadi baku emas untuk identifikasi L. pneumophila. Penelitian ini bertujuan membandingkan recovery rate L. pneumophila ATCC®33823 pada medium spesifik BCYE, dan medium selektif BMPA. Metode: Dilakukan dilusi serial pada suspensi 0,5 McFarland L. pneumophila ATCC®33823; 100 ul dari tiap tingkat dilusi diinokulasi pada medium Buffered Charcoal Yeast Extract (BCYE) dan medium BMPA (medium BCYE yang ditambahkan suplemen BMPA-α), secara duplo. Konsentrasi suspensi dihitung menggunakan metode Angka Lempeng Total (ALT) dari Standar Nasional Indonesia No. 01-2332.3-2006. Persentase recovery rate dihitung dan dianalisis secara statistik menggunakan SPSS versi 23,0. Hasil: Jumlah koloni L. pneumophila yang tumbuh pada medium BMPA jauh lebih tinggi daripada yang tumbuh di medium BCYE; konsentrasi tertinggi yang diperoleh adalah pada medium BMPA sebesar 1,45 x 107 CFU/ml. Persentase recovery rate pada medium BMPA adalah 96,67%, dan 60,67% pada medium BCYE. Kesimpulan: Recovery rate medium BMPA untuk pertumbuhan koloni L. pneumophila ATCC®33823 jauh lebih tinggi daripada media BCYE, karena itu medium BMPA dapat direkomendasikan untuk kultivasi L. pneumophila, khususnya pada program surveilans berbagai sumber air dengan biaya lebih terjangkau. Kata kunci: Legionella pneumophila, medium spesifik, BCYE , BMPA, recovery rate Abstract Background: Legionella pneumophila (L. pneumophila) has been known as the etiology of legionellosis; they live in aquatic environment, warm and moist. Culture method using specific medium remains as the gold standard in the identification of L. pneumophila. This study aimed to compare the recovery rate of L. pneumophila ATCC® 33823 on the specific medium BCYE for the cultivation of Legionella, and BMPA, the selective medium. Methods: Suspension of L. pneumophila ATCC® 33823 of 0.5 McFarland was diluted to 10 fold serial dilution; 100 ul of each dilution was inoculated on Buffered Charcoal Yeast Extract (BCYE) medium, and BMPA (BCYE supplemented with BMPA-α) in duplicate manner. The concentration was calculated using Total Plate Count standard as of Indonesian Nasional Standard number 01-2332.3-2006. The percentage of recovery rate was calculated, and the statistical analysis was performed using SPSS version 23.0. Results: Numbers of colonies of L. pneumophila grew on BMPA was much higher than on BCYE medium; the highest concentration was yielded on BMPA medium i.e. 1.45x107 CFU/ml. The recovery rates were 96.67% and 60.67% on BMPA medium and BCYE subsequently. Conclusion: The recovery rate of the BMPA medium on the colony growth of L. pneumophila ATCC®33823 was markedly higher than the BCYE, therefore BMPA medium can be suggested to be used in the cultivation of L. pneumophila especially in the routine surveillance program for water sources with less cost. Keywords: Legionella pneumophila, specific medium, BCYE , BMPA, recovery rate
Gene Families of AmpC-producing Enterobacteriaceae Present in the Intensive Care Unit of Cipto Mangunkusumo Hospital Jakarta Lucky Hartati Moehario; Thomas Robertus; Anis Karuniawati; Rudyanto Sedono; Delly Chipta Lestari; Andi Yasmon
The Indonesian Biomedical Journal Vol 11, No 1 (2019)
Publisher : The Prodia Education and Research Institute (PERI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18585/inabj.v11i1.552

Abstract

BACKGROUND: Antibiotic resistance has become a worldwide problem. Among Asia countries, Indonesia has high prevalence of multi-drug resistant organisms mainly due to Gram-negative bacilli Enterobacteriaceae. This study aimed to find out whether gene family of AmpC and AmpC/ESBL-producing Enterobacteriaceae were present in the Intensive Care Unit (ICU) of Cipto Mangunkusumo Hospital, Jakarta, Indonesia.METHODS: Specimens were obtained from several body sites of adult patients with infection hospitalised in ICU of Cipto Mangunkusumo Hospital. VITEK®2 was used to identify the microorganisms. Antibiotic susceptibility tests were conducted using VITEK®2 and disc diffusion technique according to Clinical and Laboratory Standards Institute (CLSI) guidelines. Double disc synergy (DDS) test method was employed to detect AmpC activity. Gene families of ampC were identified using multiplex polymerase chain reaction (PCR).RESULTS: Forty five isolates were identified as putative AmpC, extended-Spectrum β-lactamases (ESBL) and AmpC/ESBL-producing Enterobacteriaceae. Klebsiella pneumoniae (n=32) were predominant, followed by Escherichia coli (n=6), Enterobacter cloacae (n=5) and Enterobacter aerogenes (n=2). AmpC activity was detected in 9 isolates, in which 4 isolates were AmpC producing and 5 isolates were AmpC/ESBL. In vitro, AmpC-producing Enterobacteriaceae showed good susceptibility to many antibiotic tested, while those of AmpC/ESBL-producing only to Amikacin. The gene families of ampC were DHA, EBC and CIT identified from 6 isolates.CONCLUSION: DHA, EBC and CIT gene families were identified from AmpC and AmpC/ESBL-producing Enterobacteriaceae in the ICU of Cipto Mangunkusumo Hospital. While the AmpC-producing was still susceptible to almost all antibiotics tested, the AmpC/ESBL-producing showed resistant except for Amikacin.KEYWORDS: Enterobacteriaceae, β-lactamases, AmpC, ESBL
Aktivitas Antibakteri Ekstrak Kelopak Bunga Rosela terhadap Bakteri Multidrug Resistant Acinetobacter baumannii dan Pseudomonas aeruginosa Elisha Minarto; Irene; Lucky Hartati Moehario
Jurnal Kedokteran Meditek Vol 28 No 3 (2022): SEPTEMBER-DESEMBER
Publisher : Fakultas Kedokteran Universitas Kristen Krida Wacana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36452/jkdoktmeditek.v28i3.2366

Abstract

Penggunaan berbagai macam antibiotik menyebabkan kejadian resistensi antibiotik cepat berkembang. Acinetobacter baumannii dan Pseudomonas aeruginosa adalah bakteri multidrug resisten yang sering dikaitkan dengan terjadinya kegagalan terapi. Berbagai negara menggunakan herbal sebagai pengobatan alternatif penyakit infeksi. Studi sebelumnya menunjukkan aktivitas antibakteri yang dimiliki Hibiscus sabdariffa (rosela). Penelitian ini bertujuan untuk meneliti aktivitas antibakteri ekstrak kelopak bunga rosela pada berbagai konsentrasi terhadap bakteri Multidrug Resistant (MDR) A. baumannii dan P. aeruginosa. Kelopak bunga rosela dimaserasi menggunakan pelarut etanol 96%. Aktivitas antibakteri diuji dengan metode cakram difusi pada konsentrasi 20, 40, 60, 80, dan 100%. Hasil penelitian menunjukkan diameter zona inhibisi ekstrak kelopak bunga rosela pada konsentrasi tersebut terhadap bakteri MDR A. baumannii adalah 10,8, 15, 16,8, 17, dan 21,2 mm, dan terhadap bakteri MDR P. aeruginosa adalah 10,6, 12,2, 16,8, 18, dan 23 mm. Uji statistik menggunakan uji Kruskal-Wallis didapatkan nilai P = 0,000 (P < 0,05) yang menunjukkan perbedaan aktivitas antibakteri yang signifikan antar kelompok konsentrasi ekstrak terhadap bakteri MDR A. baumannii maupun P. aeruginosa. Kesimpulan yang didapat adalah aktivitas antibakteri ekstrak kelopak bunga rosela terhadap bakteri MDR A. baumannii dan P. aeruginosa meningkat seiring dengan peningkatan konsentrasi.
Re-Emergence of Ampicillin Sensitive Salmonella Typhi and the Increase of Ciprofloxacin Resistance in Typhoid Fever Treatment in Asia: A Systematic Review Tanjaya, Felicity; Nathan, Johan; Nainggolan, Ita Margaretha; Moehario, Lucky; Thantry, Anita Devi Krishnan; Tunru, Andi Miyanza Lakipadada; Sean, Sherlyn
Indonesian Journal of Tropical and Infectious Disease Vol. 12 No. 1 (2024)
Publisher : Institute of Topical Disease Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/ijtid.v12i1.42305

Abstract

Typhoid fever is a disease caused by Salmonella Typhi infection. In 2000, 2.16 million people were affected worldwide, with more than 90% morbidity and mortality in Asia. Ampicillin is the first-line antibiotic used for typhoid management. However, the rise in resistance to first-line antibiotics has shifted ciprofloxacin as an alternative.  This study aimed to describe the trends in ciprofloxacin- and ampicillin-resistant Salmonella Typhi in Asia. This study was a systematic review that conformed to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses criteria. Search was indicated toward studies on Salmonella Typhi susceptibility toward ciprofloxacin and ampicillin were identified using PubMed, Cochrane Library, and ProQuest. Of the 1542 studies found, only 16 fulfilled the criteria. In 1996, Salmonella Typhi was not found to be resistant to ciprofloxacin, whereas 3.5% was resistant to ampicillin. In 2005, ciprofloxacin resistance increased to 19.3%, whereas ampicillin resistance decreased to 13.3%. In 2005-2014, a larger number of Salmonella Typhi isolates resistant to ciprofloxacin than to ampicillin. Furthermore, during 2016-2019, resistance to ciprofloxacin increased from 8.1% to 95%, while ampicillin resistance increased from 27.5% to 85.2%. This the high ampicillin resistance in South and East Asia. In Asia, there was an increase in ciprofloxacin-resistant Salmonella typhi from 1996 to 2019, whereas ampicillin-resistant Salmonella Typhi decreased from 1996 to 2015.  Between 2016 and 2019, contrasting evidence was found in East Asia and South Asia, where resistance toward ampicillin increased.
Effectiveness of azithromycin and ciprofloxacin in the treatment of typhoid fever: a systematic review Mulyono, Bethea Manuela; Ita Margaretha Nainggolan; Linawati Hananta; Lucky Hartati Moehario
Indonesian Journal of Pharmacology and Therapy Vol 4 No 3 (2023)
Publisher : Faculty of Medicine, Public Health, and Nursing Universitas Gadjah Mada and Indonesian Pharmacologist Association or Ikatan Farmakologi Indonesia (IKAFARI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/ijpther.8945

Abstract

Typhoid fever or commonly referred to as enteric fever is a systemic disease caused by Salmonella typhi. It often occurs in developing countries due to poor sanitation. Second-line antibiotics, including ciprofloxacin, have been widely used as the first choice treatment for typhoid fever. However, S. typhi has increased resistance to second-line antibiotics, so azithromycin has become an alternative treatment for the typhoid fever. This systematic review assessed the effectiveness of azithromycin and ciprofloxacin against typhoid fever in adults. This research used the PRISMA protocol with predefined Pubmed, Proquest, and EBSCO keywords. After removing duplicates and selecting studies according to inclusion and exclusion criterias, 17 studies about the effectiveness of azithromycin and ciprofloxacin in typhoid fever in adults from 1988-2020 were gathered. Studies were evaluated using JBI Critical Appraisal Tools. The results showed that administration of azithromycin and ciprofloxacin for typhoid fever yields average length of fever (3.5 d and 4.2 d) and average length of stay (9.3 d and 10 d), respectively. The susceptibility of S. typhi to azithromycin was 99.9%, whereas a significant decrease in its susceptibility to ciprofloxacin was observed in 2017-2020, from 4% to 2%. Azithromycin showed better effectiveness than ciprofloxacin in treating typhoid fever in adults based on S. typhi’s susceptibility, average length of fever and average length of stay from 17 studies reviewed.
Deteksi Antigen Helicobacter pylori Pada Pasien GERD dan Non-GERD di Rumah Sakit Atma Jaya Athalia Nofera Kurniawan; Riki Tenggara; Lucky Hartati Moehario
Majalah Kedokteran Indonesia Vol 69 No 8 (2019): Journal of The Indonesian Medical Association - Majalah Kedokteran Indonesia, Vo
Publisher : PENGURUS BESAR IKATAN DOKTER INDONESIA (PB IDI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47830/jinma-vol.69.8-2019-185

Abstract

Introduction: Helicobacter pylori (H. Pylori) is one of normal human microbiota live in human stomach and often associated with dyspepsia, however, its association with Gastroesophageal Reflux Disease (GERD) is still controversial. The diagnosis of H. pylori is often established through histopathological examination, an invasive urease tests, and urea breath test (UBT. Serological tests are also used to diagnose H. pylori, one of which is Stool Antigen Test (SAT), which is cheaper, non-invasive and easier to operate. The purpose of this study was to detect H. pylori antigen in GERD and non-GERD patients at Atma Jaya Hospital.Method: This study was a descriptive cross-sectional. Participants in this study were adult patients hospitalised in Atma Jaya Hospital from August 2018 - November 2018, interviewed with GERDQ questionnaire and stool samples were collected. Stool Antigen Test was carried out using SAT from Biocare®. Results: Thirty participants were included in this study, consisted of 22 women and 8 men, and predominated by adult age group (35–64 years old). Forty percent participants were GERD group consisted of 75% women. Positive SAT test results in the GERD group was 16.67%, non-GERD was 11.11%, and negative SAT test results in the GERD group was 91.67%, non-GERD was 77.78%. Conclusion: The presence of H. pylori antigen was detected in women in the adult age group. It seemed the presence of H. pylori was not different from GERD group and non-GERD group.
Co-Authors Andi Yasmon Anis Karuniawati Athalia Nofera Kurniawan Delly Chipta Lestari Elisha Minarto Enty Eustachius Hagni Wardoyo Irene Kendrick Klaudius Hartedja Linawati Hananta, Linawati Monica Oktaviana Mulyono, Bethea Manuela Mutiara J. Taslim Nainggolan, Ita Margaretha Nathan, Johan Ocvyanty, Dwiana Prihadi, Johannes C Ricky Yue Riki Tenggara Rudyanto Sedono Sean, Sherlyn T. Robertus Tanjaya, Felicity Thantry, Anita Devi Krishnan Thomas Robertus Tunru, Andi Miyanza Lakipadada Yohanna Angelina Yuliana Grace