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All Journal e-Journal Pustaka Kesehatan Jurnal Teknosains STOMATOGNATIC- Jurnal Kedokteran Gigi Dental Journal (Majalah Kedokteran Gigi) Health Notions Journal of Dentomaxillofacial Science
Herniyati
Bagian Ortodonsia , Fakultas Kedokteran Gigi Universitas Jember
Biochemistry, Genetics & Molecular Biology Civil Engineering, Building, Construction & Architecture Dentistry Health Professions Industrial & Manufacturing Engineering Library & Information Science Mechanical Engineering Medicine & Pharmacology Nursing Public Health

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Evaluation of orthodontic tooth movement by 3D micro-computed tomography (µ-CT) following caffeine administration H. Herniyati; Happy Harmono; Leliana Sandra Devi; Sri Hernawati
Dental Journal (Majalah Kedokteran Gigi) Vol. 52 No. 1 (2019): March 2019
Publisher : Faculty of Dental Medicine, Universitas Airlangga https://fkg.unair.ac.id/en

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (496.876 KB) | DOI: 10.20473/j.djmkg.v52.i1.p1-7

Abstract

Background: The compressive strength of orthodontic tooth movement will be distributed throughout the periodontal ligament and alveolar bone, resulting in bone resorption on the pressure side and new bone formation on the tension side. Caffeine, a member of the methyl xanthine family, represents a widely-consumed psychoactive substance that can stimulate osteoclastogenesis through an increase in RANKL. A 3D Micro-Computed Tomography (µ-CT) x-ray device can be used to measure orthodontic tooth movement and changes in periodontal ligament width. Purpose: The purpose of this research was to analyze the effects of caffeine on the distal movement distance of two mandibular incisors using 3D µ-CT. Methods: The research subjects (guinea pigs) were randomly divided into four groups. Of the two control groups created, one received two weeks of treatment and the other three weeks. The members of these two control groups were subjected to orthodontic movement but received no caffeine. Meanwhile, the other two groups were treatment groups whose members also received either two or three weeks of treatment. In these two treatment groups, the subjects were subjected to orthodontic movement and received a 6 mg/500 BM dose of caffeine. The orthodontic movement of the subjects was induced by installing a band matrix and orthodontic bracket on each mandibular incisor to move distally by means of an open coil spring. Observations were then conducted on days 15 and 22 with µ-CT x-rays to measure the distal movement distance of the two mandibular incisors and the width of the periodontal ligament. Results: The administration of caffeine increased the tooth movement on day 15 (p<0.05) and day 22 (p<0.05). The increase in the tooth movement on day 22 was greater than that on day 15 (p<0.05). The width of the periodontal ligament on the pressure side of the treatment groups experienced greater narrowing than that of the control groups (p<0.05). Meanwhile, the width of periodontal ligament on the tension side of the treatment groups widened more than that of the control groups (p<0.05). Conclusion: µ-CT x-ray can be used to evaluate the extent of orthodontic movement in addition to the width of the mandibular incisor periodontal ligament during orthodontic tooth movement. Moreover, it has been established that the administering of caffeine can improve orthodontic tooth movement.
Jumlah Sel Osteoklas pada Tulang Alveolar Daerah Tekanan Gigi Tikus yang Diinduksi Gaya Mekanis Ortodonti Samahi Arrahma; Herniyati Herniyati; Dwi Prijatmoko
STOMATOGNATIC - Jurnal Kedokteran Gigi Vol 19 No 2 (2022)
Publisher : Fakultas Kedokteran Gigi Universitas Jember

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19184/stoma.v19i2.34740

Abstract

The mechanical force of orthodontics produces areas of pressure and pull. In the pressure area occurs resorption of alveolar bones carried out by osteoclast cells. The study aims to find out the change in the number of osteoclast cells in the alveolar bone pressure area of mouse teeth that induced mechanical force orthodontics. 36 male rats are divided into 6 groups. Group K: mice are not given a mechanical style of orthodontics. Group P: mechanically styled orthodontics (GMOs). GMOs in mice were administered to the upper jaw molar-1 (M-1) teeth (RA) right and in both RA incisive teeth using Ni-Ti Orthodontic Closed Coil Spring diameter 0.01 inches in orthodontic force of 3.5 oz = 85.05 gr/cm2 = 10 grF for 1 week, 2 weeks and 3 weeks. The results of the study were 1 week (1.99), 2 weeks (1.92), and 3 weeks (1.75). Conclusion of mechanical administration of orthodontic force increases the number of osteoclast cells on the 8th day (1 week), the 15th (2 weeks), and the 22nd (3 weeks). Based on the observation time there was a decrease in the number of osteoclast cells from 1 week to 2 weeks then to 3 weeks but not significant.
Bioactive potential of edel cocoa bean (theobroma cacao L) from Kedaton Jember: Cytotoxicity and antioxidants evaluation Rina Sutjiati; Leliana S. Devi; Dwi Prijatmoko; Herniyati; Rudy Joealijanto; Erna Sulistyani; Bilqis P. Safitri; Nihla Fitriyani
Journal of Dentomaxillofacial Science Vol. 7 No. 1 (2022): (Available online: 1 April 2022)
Publisher : DiscoverSys Inc.

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15562/jdmfs.v7i1.1401

Abstract

Objective: Kedaton, a small village located in Jember is well known as one of the largest edel cocoa producers in the world. The cocoa beans contain nutrients and numerous beneficial properties, one of them is flavonoids, that work as antioxidants that can be utilized in dentistry, particularly orthodontics. The use of plants for the treatment must be ensured as safe without any toxic properties. Material and Methods: This study use DPPH (2,2-diphenyl-1-picryl-hydrazyl-hydrate) free radical method to evaluate antioxidant properties and MTT 3-(4.5-Dimethylthiazol-2-yl)-2.5-diphenyltetrazolium bromide assay to assess the fibroblast cell activity. Results: The fermented edel cocoa bean extract exhibited the IC50 value of 33.97 ppm and the unfermented edel cocoa bean extract that had the IC50 value of 9.56 ppm. Both of them have very strong antioxidant activity. Fermented edel cocoa bean extract in concentrations of 1.56%, 3.125%, 6.25%, and 12.5%; as well as unfermented edel cocoa bean extract in concentrations of 1.56% and 3.125% did not have cytotoxic effects to fibroblasts. Conclusion: The unfermented edel cocoa bean extracts have higher antioxidant activity compared to fermented ones. The fermented edel cocoa bean extracts did not have cytotoxic effect, meanwhile the unfermented edel cocoa bean extracts in concentrations of 6.25% and 12.5% have cytotoxic effect to fibroblasts.
Ekspresi BMP2 dan TRAF6 pada Jaringan Periodontal setelah Pemberian Ekstrak Kopi Robusta selama Pergerakan Gigi Ortodonti Herniyati Herniyati; Leliana Sabdra deviade Putri; Hestieyonini Hadnyanawati; Happy Harmono
Pustaka Kesehatan Vol 11 No 2 (2023): Volume 11 No.2, 2023
Publisher : UPT Percetakan dan Penerbitan Universitas Jember

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19184/pk.v11i2.38029

Abstract

Orthodontic tooth movement occurs due to mechanical stimulation followed by alveolar bone and periodontal ligament remodeling. Bone remodeling is the process of bone resorption in areas of tension and bone formation in areas of tension. Various techniques and drugs are used to speed up orthodontic treatment. This study aims to analyze the expression of BMP2 and TRAP6 on orthodontic tooth movement after the administration of Robusta coffee extract. Twenty-four Wistar rats were divided into 4 groups: C1 (2 weeks) and C2 (3 weeks) groups: rats were given orthodontic mechanical force (OMF) and T1 (2 weeks) and T2 (3 weeks) groups rats were given OMF and Robusta coffee extract. OMF in rats was performed by moving the maxillary right permanent molars mesially with a Niti closed coil spring. Observations were made on the 15th and 22nd day by immunohistochemical examination to determine the expression of BMP2 and TRAP6. Administration of Robusta coffee extract for 2 weeks and 3 weeks increased BMP2 and TRAP6 expression (p <0.05). Administration of Robusta coffee extract increased the expression of BMP2 and TRAP6 in the alveolar bone during orthodontic tooth movement.
Co-Authors Adik Wulandari Arimbi Gupitasari Banun Kusumawardani Bilqis P. Safitri Dani Agam Rahmadianto Dita Nur Ekasari Dwi Prijatmoko Erna Sulistyani Ginanjar Hidayatullah Happy Harmono Hestieyonini Hadnyanawati Ida Bagus Narmada Leliana S. Devi Leliana Sabdra deviade Putri Leliana Sandra Devi Ade Putri Nihla Fitriyani Reganita Nurmaulawati Saputri Rina Sutjiati Rudi Joelijanto Rudy Joealijanto Samahi Arrahma SOETJIPTO . Sri Hernawati Vananda Duanta Kantasa