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EFFECTIVENESS TEST OF INSULIN (Thitonia diversifolia (Hemsl.) A. Gray) LEAF INFUSION ON DECREASING BLOOD GLUCOSE LEVELS IN MALE WHITE MICE (MUS MUSCULUS) Brata, Andy; Pratiwi, Yossie Bella
Jurnal Bahana Kesehatan Masyarakat (Bahana of Journal Public Health) Vol 3 No 2 (2019): Jurnal Bahana Kesehatan Masyarakat (Bahana of Journal Public Health)
Publisher : Poltekkes Kemenkes Jambi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35910/jbkm.v3i2.225

Background: Insulin leaf is one of the plants that has the use of its leaves. Insulin leaves contain flavonoids that are thought to reduce blood glucose levels. This study aims to determine the effectiveness of insulin leaf infusion on decreasing blood glucose levels in male white mice. Methods: This study was an experimental study with a Pretest-Posttest with Control Group design. Test animals used were 25 male white mice which were divided into 5 groups, namely the negative control group (Na-CMC), positive control group (Glibenklamid), insulin leaf infusion group 420 mg, 840 mg, and 1260 mg. Observation and checking of blood glucose levels in mice in the 30th, 60th, 90th, and 120th minutes. Results: One-Way ANOVA statistical test results showed significant results in the 90th and 120th minutes. Followed by the Duncan Post Hoc test which showed the best dose, ie a dose of 420 mg which had an effect comparable to Glibenclamide 5 mg, then followed by a dose of 1260 mg and 840 mg which already have antihyperglycemic effects but no difference has been seen. Conclusion: The dose of infusion that can reduce blood glucose levels is a dose of 420 mg with a decrease in maximum blood glucose levels in the 90th minute and 120th minute.

Pengembangan Bahan Ajar Kimia Organik Berbasis Konstruktifisme Development of Constructivism-Based Organic Chemistry Teaching Materials Kurniasih, Dewi; Brata, Andy; Sabarudin, Sabarudin
SCIENTIA JOURNAL Vol 9 No 2 (2020): SCIENTIA JOURNAL
Publisher : Universitasdiwangsa Jambi

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Latar Belakang : Bahan ajar merupakan sumber belajar yang sangat penting dalam melaksanakan kegiatan pembelajaran di kelas. Mengingat ilmu kimia mempunyai tingkat kesulitan yang tinggi berkaitan dengan konsep-konsep yang bersifat abstrak serta untuk menghindari terjadinya miskonsepsi terhadap materi ajar kimia organik maka perlu adanya bahan ajar yang digunakan sebagai pedoman dalam pembelajaran. Menurut BSNP, bahan ajar yang baik adalah bahan ajar yang memenuhi 4 komponen kelayakan yaitu kelayakan isi, kelayakan penyajian, kelayakan bahasa dan komponen kegrafikaan. Metode : Penelitian ini adalah penelitian pengembanganatau Research and Development (R&D) yang bertujuan untuk mengembangkan bahan ajar berbasis kostruktifisme menggunakan model Dick and Carey. Luaran yang dihasilkan dari penelitian ini adalah berupa sebuah buku atau modul yang berisi bahan ajar Kimia Organik. Dalam penyajiaannya bahan ajar tersebut mampu mengajak dan memotivasi mahasiswa membangun pengetahuannya sendiri dengan menemukan dan menyimpulkan serta menganalisis setiap teori di yang disajikan di kelas dan layak digunakan sebagai sumber belajar. Teknik pengumpulan data meliputi wawancara angket, telaah ahli materi oleh ahli desain pembelajaran dan uji coba produk, evaluasi terhadap uji coba menjadi dasar untuk merevisi produk bahan ajar. Kelayakan produk bahan ajar telah lolos uji dengan proses validasi oleh ahli dari Fakultas Keguruan Ilmu Pendidikan (FKIP) Universitas Jambi dan ahli Fakultas Tarbiah Universitas Islam Negeri STS Jambi. Daya tarik produk bahan ajar telah diuji dalam uji coba kelompok kecil dan uji coba kelompok besar dengan nilai 80,13%. Efektifitas produk telah diuji menggunakan angket penilaian kinerja terhadap bahan ajar pada uji coba kelompok besar dengan perolehan nilai 72,71 %. Saran : Untuk memperoleh hasil belajar yang maksimal mahasiswa disarankan agar mengetahui dan memahami tujuan pembelajaran pada tiap-tiap bagian materi ajar, membaca dan memahami bagian pendahuluan, uraian dan rangkuman sebelum mengerjakan soal latihan maupun evaluasi. Kesimpulan Daya tarik produk bahan ajar telah diuji dalam uji coba kelompok kecil dan uji coba kelompok besar dengan nilai 80,13%. Efektifitas produk telah diuji menggunakan angket penilaian kinerja terhadap bahan ajar pada uji coba kelompok besar dengan perolehan nilai 72,71 %.

Analysis of Pharmaceutical Care Services in Hospital Pharmacy Installation in Jambi City Andy Brata; Lailan Azizah
Jurnal Bahana Kesehatan Masyarakat (Bahana of Journal Public Health) Vol 2 No 2 (2018): Jurnal Bahana Kesehatan Masyarakat (Bahana of Journal Public Health)
Publisher : Poltekkes Kemenkes Jambi

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (666.866 KB)

Abstract Background: The care of pharmacy or Pharmaceutical care is a form of optimizing the role performed by pharmacists on patients in conducting medical therapy so that they can improve the patient's health status. Pharmacists play a role in providing consultation, information and education (IEC) related to the treatment therapies that patients undergo, directing patients to adopt healthy lifestyles so that the treatment success can be achieved, and monitoring the results of treatment therapies that have been carried out by patients and collaborating with other health professions which of course aim to improve the quality of life of patients. The purpose of the study was to determine the implementation of pharmacist practices in hospitals in Jambi City and pharmacist awareness of the implementation of pharmacy care in hospitals in Jambi City Method: The sample was determined by 55 pharmacists, who were selected by exhause sampling. Conclusion: The results of the study showed that simultaneously both dimensions of pharmaceutical services had a significant effect on the implementation of pharmaceutical care; while partially one variable (pharmacist awareness about pharmacy care) has a significant influence (p <0.05), while the current pharmacist practice variable in the hospital does not have a significant effect. Pharmacy care services in hospital pharmacy installations in Jambi city are not influenced by current pharmaceutical practices in hospitals. Where pharmacists consider awareness of pharmacy care services while in practice not. So that the implementation of pharmacy care is influenced by the pharmacist's awareness of the care of pharmacy.

EFFECTIVENESS TEST OF INSULIN (Thitonia diversifolia (Hemsl.) A. Gray) LEAF INFUSION ON DECREASING BLOOD GLUCOSE LEVELS IN MALE WHITE MICE (MUS MUSCULUS) Andy Brata; Yossie Bella Pratiwi
Jurnal Bahana Kesehatan Masyarakat (Bahana of Journal Public Health) Vol 3 No 2 (2019): Jurnal Bahana Kesehatan Masyarakat (Bahana of Journal Public Health)
Publisher : Poltekkes Kemenkes Jambi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35910/jbkm.v3i2.225

Background: Insulin leaf is one of the plants that has the use of its leaves. Insulin leaves contain flavonoids that are thought to reduce blood glucose levels. This study aims to determine the effectiveness of insulin leaf infusion on decreasing blood glucose levels in male white mice. Methods: This study was an experimental study with a Pretest-Posttest with Control Group design. Test animals used were 25 male white mice which were divided into 5 groups, namely the negative control group (Na-CMC), positive control group (Glibenklamid), insulin leaf infusion group 420 mg, 840 mg, and 1260 mg. Observation and checking of blood glucose levels in mice in the 30th, 60th, 90th, and 120th minutes. Results: One-Way ANOVA statistical test results showed significant results in the 90th and 120th minutes. Followed by the Duncan Post Hoc test which showed the best dose, ie a dose of 420 mg which had an effect comparable to Glibenclamide 5 mg, then followed by a dose of 1260 mg and 840 mg which already have antihyperglycemic effects but no difference has been seen. Conclusion: The dose of infusion that can reduce blood glucose levels is a dose of 420 mg with a decrease in maximum blood glucose levels in the 90th minute and 120th minute.

GAMBARAN KINERJA PENGELOLA DI PUSKESMAS KOTA JAMBI Andy Brata; Haflin Haflin
Jurnal Bahana Kesehatan Masyarakat (Bahana of Journal Public Health) Vol 4 No 1 (2020): Jurnal Bahana Kesehatan Masyarakat (Bahana of Journal Public Health)
Publisher : Poltekkes Kemenkes Jambi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35910/jbkm.v4i1.240

Background: Pharmaceutical services at this time have changed their paradigm from drug to patients orientation, which refers to pharmaceutical care. As a consequence, pharmacists are required to improve their knowledge, skills and behavior so that they can interact directly with patients. Pharmaceutical services include the management of pharmaceutical preparations and medical consumables and clinical pharmacy services by utilizing personnel, funds, infrastructure, facilities and appropriate management methods in an effort to achieve the stated goals. The purpose of the study was conducted to determine the performance of drug managers in Jambi City Health Center according to Public Health Centre No. criteria. 74 of 2016. Method: The type of research used was explanatory research, conducted on drug management officers who work at the Jambi City Health Center. The sample was determined 20 drug management officers, selected by total sampling. Data was collected by distributing questionnaires to assess the performance of drug management officers on drug management at the Public Health Centre in Jambi City. The research variable was the performance of the drug manager in the Public Health Centre, the indicators of which are years of service, the commitment of the leaders, the knowledge possessed by the drug manager. The data then analyzed using Multiple Linear Regression technique. Results: The study showed that simultaneously the three dimensions of drug management had a significant effect on the performance of drug management; while partially one variable (leader commitment) has a significant effect (p <0.05), while the tenure and knowledge variables do not have a significant effect. The performance of drug management in the Jambi City Health Center is not affected by the years of service and knowledge of drug management officers. Conclusion: The performance of drug management was influenced by the commitment of the leader.

PENGARUH KEHADIRAN APOTEKER TERHADAP PELAYANAN KEFARMASIAN DI APOTEK DALAM KOTA JAMBI Supriadi Supriadi; Defirson Defirson; Andy Brata
Jurnal Bahana Kesehatan Masyarakat (Bahana of Journal Public Health) Vol 6 No 2 (2022): Jurnal Bahana Kesehatan Masyarakat (Bahana of Journal Public Health)
Publisher : Poltekkes Kemenkes Jambi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35910/jbkm.v6i2.591

Background: The presence of pharmacists in pharmaceutical services at pharmacies is not only related to drug problems but pharmacists are also expected to increase knowledge, skills, and behavioral competencies so that they can carry out professional practices, can also interact with patients in terms of drug indications, dosages, side effects, use and provision of drug information and counseling to patients to ensure safe, effective and rational treatment. The purpose of this study was to examine the effect of the pharmacist's presence on pharmacy services at pharmacies in the city of Jambi. Method: This research was a cross-sectional study using a questionnaire from March to September 2022. The study population is pharmacists at pharmacies in Jambi City. The research sample was 110 pharmacists in pharmacies who were taken at random. Result: Linear regression analysis showed that there was an effect of the frequency of pharmacist presence and having a pharmacist assistant on pharmacy services with a significance of p=0.000 and 0.013, respectively. So simultaneously there is an effect of the pharmacist's presence on pharmaceutical services with a significance p-value = 0.000 Conclusion: There was a significant effect of the pharmacist's presence on pharmaceutical services in pharmacies in Jambi City.

Uji efek antipiretik infusa daun sungkai (Peronema canescens) pada mencit putih jantan (Mus musculus) Andy Brata; Efriliya Andila Wasih
Riset Informasi Kesehatan Vol 10 No 2 (2021): Riset Informasi Kesehatan
Publisher : Sekolah Tinggi Ilmu Kesehatan Harapan Ibu Jambi

Latar Belakang: Indonesia adalah Negara dengan iklim tropis yang mana memiliki kekayaan alam tumbuh-tumbuhan di Indonesia meliputi lebih kurang 30.000 jenis tumbuh-tumbuhan diantaranya adalah tumbuhan yang berkhasiat obat. Pada sekarang ini masih banyak terdapat tumbuhan yang berkhasiat obat tumbuh secara liar dan belum dimanfaatkan. Salah satu tumbuhan obat yang memiliki khasiat untuk menurunkan demam atau antipiretik adalah Sungkai (Peronema canescens). Rumusan masalah dari penelitian ini apakah infusa daun Sungkai (Peronema canescens) memiliki efektifitas sebagai antipiretik terhadap mencit putih jantan yang sudah diinduksi dengan menggunakan pepton. Tujuan dari penelitian ini adalah untuk mengetahui ada atau tidaknya pengaruh efek antipiretik infusa daun Sungkai (Peronema canescens) terhadap mencit putih jantan. Dari hasil penelitian sebelumnya, diketahui bahwa daun muda Peronema Canescens adalah bahan baku obat herbal yang dapat digunakan untuk menurunkan panas atau demam. Metode: Penelitian ini merupakan penelitian Pra Eksperimen dengan menggunakan desain penelitian The Static-grup Comparison yakni jenis penelitian eksperimen yang membuat dua kelompok objek penelitian yaitu satu kelompok untuk kontrol dan satu kelompok lagi yang menerima intervensi atau perlakuan. Penelitian ini menggunakan sebanyak 25 ekor mencit putih jantan yang dibagi menjadi 5 kelompok, 2 kelompok untuk kelompok kontrol positif paracetamol dan negatif Na-CMC 5%, 3 kelompok lagi untuk dilakukan perlakuan dengan dosis 10%, 20% dan 30%. Hasil: Terdapat ada pengaruh yang signifikan pada pemberian dosis infusa daun sungkai (Peronema canescens) terhadap suhu tubuh mencit (Mus musculus) pada saat 30, 60, 90 dan 120 menit setelah diberikan perlakuan. Kesimpulan: Pemberian infusa daun sungkai dengan dosis 10% dan 20% menurunkan suhu tubuh mencit lebih efektif.

ANALGETIC ACTIVITY TEST OF ETHANOL EXTRACT SUNGKAI LEAF (Peronema canescens Jack) IN WHITE MALE MOUSE (Mus musculus) INDUCED WITH ACETIC ACID Lia Wahyuni; Dona Muin; Defirson Defirson; Andy Brata
Jurnal Farmasi Sains dan Praktis Vol 9 No 2 (May-August 2023)
Publisher : Universitas Muhammadiyah Magelang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31603/pharmacy.v9i2.7374

Traditional medicine, which is generally considered safer than modern medicine, makes people choose alternative treatments using medicinal plants, one of which is to treat pain. One of the medicinal plants used to treat pain is a plant that contains flavonoids, one of which is the Sungkai plant (Penorema canescens Jack). The research design used was The Static Group Comparison, where the test animals used were divided into 5 groups, each group consisting of 5 mice. Group 1 was given 1 percent of CMC. Group II was given ethanol extract of Sungkai leaves at a dose of 300 mg/Kg BW. Group III was given EEDS at a dose of 600 mg/kg BW. Group IV was given EEDS at a dose of 900 mg/Kg BW. Group V was given paracetamol suspension. The results showed that there was an analgesic activity in the EEDS group, dose I was 50 percentage, dose II was 55,798 percentage, and dose III was 69,564 percentage. The study concluded that statisti-cally there was no significant difference in analgesic activity in white male mice between the EEDS doses I, II, and III groups and the paracetamol group.

Sosialisasi pemanfaatan tanaman bunga pukul empat sebagai tanaman hias dan obat pemeliharaan wajah Andy Brata
Jurnal Pengabdian Harapan Ibu (JPHI) Vol 4 No 2 (2022): Jurnal Pengabdian Harapan Ibu (JPHI)
Publisher : Sekolah Tinggi Ilmu Kesehatan Harapan Ibu Jambi

Salah satu tanaman hias bernama Bunga Pukul Empat (Mirabilis jalapa) telah digunakan turun temurun sebagai obat kecantikan yang berkhasiat menghilangkan jerawat. Ekstrak bunga tanaman tersebut terbukti memiliki kemampuan membunuh bakteri. Masyarakat perlu diberikan penyuluhan untuk menggunakan obat tradisional dalam bentuk ekstrak yang sederhana yang dapat dilakukan secara sendiri atau kelompok masyarakat. Perubahan dalam perilaku pemanfaatan obat tradisional dimulai dari manfaat ganda yang diperoleh. Fungsinya sebagai tanaman hias mendorong masyarakat untuk memanfaatkan juga sebagai obat. Bentuk ekstrak dipilih karena telah terbukti secara ilmiah khasiatnya. Tujuan dari pengabdian ini adalah untuk meningkatkan pengetahuan masyarakat tentang pemanfaatan obat tradisional dengan benar dalam bentuk ekstrak yang sederhana. Metode yang digunakan adalah melakukan penyuluhan berupa penyampaian materi dalam bentuk ceramah dan diakhiri dengan sesi tanya jawab. Hasil yang diperoleh yaitu masyarakat mendapatkan pengetahuan tentang pemanfaatan tanaman bunga pukul empat sebagai obat pemeliharaan wajah. Pengetahuan masyarakat tentang pemanfaatan obat tradisional dengan benar dalam bentuk ekstrak yang sederhana meningkat menjadi 100%.

EFEKTIVITAS PENGGUNAAN INFUSA DAUN BENGKAL (Nauclea Orientalis L.) SEBAGAI ANTIDIABETES TERHADAP HEWAN MENCIT Andy Brata; Lailan Azizah; Dona Muin
Jurnal Bahana Kesehatan Masyarakat (Bahana of Journal Public Health) Vol 7 No 2 (2023): Jurnal Bahana Kesehatan Masyarakat (Bahana of Journal Public Health)
Publisher : Poltekkes Kemenkes Jambi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35910/jbkm.v7i2.650

Background: Bengkal leaves (Nauclea orientalis L.) is a plant that contains flavonoids that act as active substances in reducing blood glucose levels (antidiabetic). The effectiveness of Bengkal leaf decoction (Nauclea orientalis L.) used by the public is still not known as an antidiabetic agent. This research was conducted to test the effectiveness of using Bengkal leaf infusion (Nauclea orientalis L.), used by the community as an antidiabetic test using male white mice that had been induced with alloxan previously. Method: This study used a quasi-experimental study with a static-group comparison design. The experimental animals used were thirty male white mice divided into six groups, namely the negative control group (Tragakan), the positive control group (alloxan), the comparison group (glibenclamide), the Bengkal leaf infusion group with percentages of 10, 20, and 30 Next, testing was carried out by measuring blood sugar levels in mice starting from day 7, 14 to 21. Then one way ANOVA statistical test was carried out to obtain significant results on which day was the most effective. Then Duncan's post hoc test was to determine the best concentration with an effect close to 5 mg of glibenclamide so that it would be known whether Bengkal leaf infusion (Nauclea orientalis L.) is effective as an antidiabetic. Later, in the end, find out whether the community can use Bengkal leaf infusion as an antidiabetic drug. Results: After statistical tests, it was proven that Bengkal leaf infusion with a percentage of 10, 20, and 30 effectively reduced blood sugar levels in mice with a significance of p = 0.000. The best levels affecting the comparison on day 21 are 20 and 30 percent infusions. Conclusion: There is effectiveness in using Bengkal infuse leaf infusion (Nauclea orientalis L.) as an antidiabetic so that the community is an antidiabetic drug.

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