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Sherly Usman
Universitas Muhammadiyah Yogyakarta
Religion Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Dentistry Economics, Econometrics & Finance Education Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Medicine & Pharmacology Neuroscience Nursing Public Health Social Sciences Veterinary Other

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Pembelajaran Tatap Muka Anak Usia Dini dengan Sehat dan Aman Siti Aminah Tri Susila Estria; Sherly Usman
Prosiding Seminar Nasional Program Pengabdian Masyarakat 2022: 1. Peningkatan Kapasitas Kelembagaan Publik
Publisher : Universitas Muhammadiyah Yogyakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18196/ppm.51.996

Abstract

Kegiatan pembelajaran tatap muka di Taman Kanak-kanak dan Kelompok Bermain Aisyiyah Rejodani yang merupakan amal usaha Pimpinan Ranting Aisyiyah (PRA) Sariharjo Utara telah dilaksanakan, setelah hampir 2 tahun berhenti dikarenakan adanya pandemi Covid-19-19. Paparan bahan pembersih tangan (BPT) saat mencuci tangan dalam jangka lama dapat mengakibatkan kulit kering atau iritasi. Hal ini membutuhkan pemahaman pemakaian dan pencegahan efek samping pemakaian BPT dengan benar. Oleh karena itu perlu dilakukan kegiatan peningkatkan pengetahuan dan perilaku guru serta siswa dalam pemilihan dan penggunaan BPT serta pencegahan efek samping pemakaian BPT. Kegiatan pemberdayaan diawali dengan observasi dan diskusi kelompok terarah untuk menetapkan teknis kegiatan, dilanjutkan dengan pengadaan BPT dan pembuatan materi. Hasil observasi ditemukan perilaku mencuci tangan telah dilaksanakan dengan baik, namun beberapa siswa dan guru mengalami kulit kering. Kegiatan inti berupa ceramah dan diskusi serta penyerahan BPT dan alat kesehatan dengan dihadiri oleh 40 orangtua siswa dan 20 orang guru TK/ KB dan PRA. Evaluasi kegiatan dilaksanakan pre dan post-test melalui Googleform. Hasil evaluasi menunjukkan peningkatan pengetahuan sebesar 11%. Wawancara dengan peserta menyatakan pemberian materi merupakan hal yang baru diketahui dan berharap kegiatan serupa dapat dilaksanakan kembali. Kegiatan ini dapat diterapkan dengan pemakaian BPT dan mengelola kesehatan kulit dengan benar, sehingga efek samping pemakaian BPT dapat dihindari
Pembinaan Ibu-Ibu Kader PKK Mengenai Pengelolaan Gangguan Metabolik di Sleman, DIY Sherly Usman; Muhammad Khotibuddin; Dwi Nur Ahsani
Prosiding Seminar Nasional Program Pengabdian Masyarakat 2022: 3. Kesehatan Keluarga dan Masyarakat
Publisher : Universitas Muhammadiyah Yogyakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18196/ppm.53.1123

Abstract

Sindrom metabolik merupakan kumpulan faktor risiko penyakit kardiovaskular yang terjadi bersamaan, yaitu peningkatan glukosa darah puasa, obesitas sentral, dislipidemia, dan hipertensi. Di Indonesia, prevalensi kejadian mencapai 23,34%. Pola konsumsi, usia, dan aktifitas fisik berpengaruh pada risiko sindrom metabolik. Pengelolaan resiko penting untuk mengurangi angka prevalensi kejadian. Pengetahuan yang baik mengenai sindrom metabolik dan pengelolaannya dapat menurunkan kejadian. Informasi mengenai pengelolaan kesehatan metabolik bisa disampaikan oleh ibu-ibu kader Pemberdayaan dan Kesejahteraan Keluarga (PKK) di dusun yang mendapatkan pelatihan dan pendampingan oleh tim kesehatan. Tujuan kegiatan ini untuk memberikan Pendampingan dan penyuluhan kepada ibu-ibu PKK di dusun mengenai gangguan metabolik sehingga meningkatkan pengelolaan gangguan metabolik masyarakat di dusun. Kegiatan diawali pemberian pretest untuk screening pengetahuan awal. Kegiatan dilanjutkan dengan pendampingan dan penyuluhan secara periodik baik secara luring dan daring oleh tim pengabdi. Pendampingan diberikan berupa pemberian materi mengenai sindrom metabolik, kajian pengelolaan nutrisi, dan aktifitas fisik dengan pakar di bidang kesehatan umum dan bidang gizi. Akhir kegiatan dilakukan post-test untuk evaluasi. Pemberian pretest untuk screening awal menunjukan nilai rata-rata 34,38. Nilai post-test menunjukkan nilai rata-rata 78,13. Hasil ini menunjukkan terdapat peningkatan pengetahuan peserta terhadap pengelolaan gangguan metabolik setelah dilakukan pembinaan dan pemdampingan dengan uji willcoxon menunjukkan perbedaan yang bermakna antara nilai rata-rata pretes dan postes. Implikasi kegiatan penting dilakukan kegiatan pemeriksaan kesehatan warga Ngemplak yang melibatkan peserta yang mendapatkan pelatihan
Penguatan Pengetahuan Diabetes Mellitus bagi Kader Posyandu Ika Setyawati; Sherly Usman; Amilia Yuni Damayanti
Prosiding Seminar Nasional Program Pengabdian Masyarakat 2022: 3. Kesehatan Keluarga dan Masyarakat
Publisher : Universitas Muhammadiyah Yogyakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18196/ppm.53.1124

Abstract

Diabetes melitus merupakan penyakit degeneratif kronis akibat dari penurunan fungsi organ. Diabetes mellitus termasuk kelainan endokrin yang ditandai dengan peningkatan kadar glukosa dalam darah atau hiperglikemia. Kelainan ini dapat disebabkan oleh kerusakan sel beta pankreas dalam memproduksi insulin atau menurunnya kepekaan dari reseptor insulin (resistensi insulin). Menurut World Health Organization, diperkitan 300 juta orang di dunia menderita DM pada tahun 2025. Salah satu peran penting masyarakat dalam upaya mencegah peningkatan laju jumlah kasus DM adalah dengan penguatan pengetahuan bagi para kader posyandu terkait DM. Hasil kegiatan didapatkan sebanyak sembilan belas kader posyandu yang mendapatkan edukasi Kesehatan dan meningkat pengetahuannya terbukti dengan rerata nilai pos-test lebih tinggi dari nilai pre-test. Simpulan kegiatan ini adalah terdapat peningkatan pengetahuan kader posyandu DM.
The Effects of Cayenne Pepper Juice (Capsicum frutescens L.) on Decreasing the Number of Goblet Cells in the Small Intestine Mucosa of Rats Usman, Sherly; Makiyah, Sri Nabawiyati Nurul; Danantika, Wiriasti
Berkala Kedokteran Vol 20, No 2 (2024)
Publisher : Fakultas Kedokteran Universitas Lambung Mangkurat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20527/jbk.v20i2.20578

Abstract

Cayenne pepper contains capsaicin and irritates the mucous of the digestive tract. Goblet cells play a role in mucosal defense because they produce mucin. In previous research, cayenne pepper juice caused gastric mucosal damage and improve at certain doses. This Research is a continuation of previous research, which was to determine the effect of cayenne pepper on the number of goblet cells of the small intestine mucosa of rats and is additional material for the development of therapy for digestive disorders. An experimental study with a post-test only and control group design, used 20 male rats, divided into 1 control (K) and 4 treatment groups (C45, C90, D135, and E180). Cayenne pepper juice was given according to the dose of the group using a gastric probe for 6 days. On the 7th day, the small intestine was taken and processed on histological preparation. Microscopic observations of goblet cells counted on average every 100 epithelia in 20 villi in 15 fields of view and the mean number was tested by One Way ANOVA and Post Hoc test. Analysis showed a significantly different mean number of goblet cells between groups (p<0.05), the highest was in the C135 (34.100 ± 1.274), the lowest mean was in the K (12.050 ± 0.462), and there was a decrease in the mean number in the C180 (28.525 ± 2.309). Cayenne pepper juice had effected the highest increase in the number of goblet cells at a dose of 135 mg and decreased at the dose of 180 mg of cayenne pepper in the small intestine of rats. 
Histology of Small Intestinal in Hypothyroid Model Rats Sherly Usman; Aisyah Luthfia Firdasari; Zulkhah Noor
Proceedings International Conference on Sustainable Innovation (ICoSI) Vol. 1 No. 1 (2021): Maximizing Opportunities and Research for a Better Life
Publisher : Universitas Muhammadiyah Yogyakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18196/icosi.v3i1.28

Abstract

More than 700,000 people were diagnosed with hypothyroidism, in Indonesia case is quite large. The study aims to see differences in the histological features of villi epithelium small intestine mucosa hypothyroid rats. The design was experimental post only group. This hypothyroidism is obtained by giving daily drinks that have been mixed with 0.025% Propylthiouracil (PTU).Ten of Subjects were divided into 2 groups: group 1 (control) and group 2 (hypothyroid), each group consisted of 5 mice. The PTU treatment was carried out for 8 weeks. Decapitation was carried out with chloroform and Intestinal organs were taken by opening the stomach. Intestinal organ then processed into histological preparations. The preparations are seen for changes in the histological picture through a microscope by scoring the damage to the intestinal mucosa. Data analysis used the Shapiro-Wilk and Independent T test. In control group showed bleeding was moderate. In hypotyroidism group showed heavy bleeding intestinal mucosa, while necrosis and erosion showed mild criteria. This research is be able to provide scientific support through data regarding histology of the mucosal lining of the small intestine in hypothyroid rat models. Conclusion: Histology of small intestinal in hypotyroid model rats showed damage mucosa with erosion, bleeding and necrosis.
HISTOPATHOLOGICAL OVERVIEW OF SMALL INTESTINE IN RATS MODEL OF INFLAMMATION INDUCED BY CHILI PEPPER Usman, Sherly; Nurusyifa, Hanifah
Jurnal Kesehatan Tambusai Vol. 6 No. 2 (2025): JUNI 2025
Publisher : Universitas Pahlawan Tuanku Tambusai

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/jkt.v6i2.46966

Abstract

Cabai rawit memiliki sifat antioksidan namun di sisi lain memicu inflamasi yang mengatur sel makrofag untuk memproduksi sitokin. Tujuan penelitian ini adalah untuk mengetahui gambaran histopatologi usus halus pada tikus model inflamasi yang diinduksi cabai rawit. Penelitian ini merupakan penelitian quasi eksperimental dengan rancangan posttest only control group design. Sebanyak 20 ekor tikus wistar putih dibagi menjadi kelompok kontrol (K) dan 4 kelompok perlakuan (C45, C90, C135, dan C180). Kelompok perlakuan diberikan infusa cabai rawit masing-masing 45 mg, 90 mg, 135 mg, dan 180 mg selama 6 hari. Pada hari ke-7 terminasi, usus halus dibuat preparat histologi pewarnaan HE. Data skoring derajat perdarahan dianalisis dengan menggunakan uji normalitas Saphiro Wilk, uji parametrik One Way Anova dan uji Post Hoc. Hasil penelitian menunjukkan adanya perdarahan epitel pada kelompok perlakuan. Perdarahan paling berat terjadi pada kelompok C135 dan perbaikan terjadi pada kelompok C180. Derajat perdarahan bermakna (p<0,05) antara kelompok kontrol dengan kelompok C135 dan C180, kelompok C45 dengan kelompok C135, dan kelompok C45 dengan kelompok C180. Kesimpulan: Gambaran histopatologi mukosa usus halus berupa perdarahan epitel paling berat pada dosis infus cabai rawit 135 mg/hari dengan perbaikan mukosa pada dosis infus 180 mg/hari.
Risk Factors for Exposure to Laboratory-Confirmed Covid-19 Patients as Early Detection of Workers Groups Sherly Usman; Titiek Hidayati; Akrom Akrom; Aida Ainun Nisa
Jurnal Aisyah : Jurnal Ilmu Kesehatan Vol 7, No S2 (2022): Suplement 2
Publisher : Universitas Aisyah Pringsewu

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (690.211 KB) | DOI: 10.30604/jika.v7iS2.1438

Abstract

The COVID-19 pandemic spreads very quickly this will undoubtedly impact healthcare workers (HCW) for COVID-19 transmission. A safety-oriented co-sufferer service system for all becomes urgent to be realized. The risk factors for COVID exposure to HCW have not been identified to date. The study aims to identify risk factors for COVID-19 exposure in HCW. This study performed a systematic review of selected journals following the study's objectives. Search journals by keywords by the Problem (HCW co-19 infection), intervention (PPE, shift duration, job), Comparison (physical distance, workload, placebo), and Outcome (odds ratio, risk ratio) (PICO) conducted at Pubmed and Google Scholar. The selection criteria include all types of literature published by peer-reviewed journals, original articles, or short communication published in 2019-2020. Researchers extract journal identity, authors, methods, Results, and conclusions. The data extraction is analyzed and presented descriptively. This study reviewed six articles. Undergraduate education, clinician job, and age increase the risk of COVID-19 exposure. Workload factors and types of services related to an increased risk of COVID-19 exposure are working on the night shift, working longer than 8 hours, intubation services, and working in the emergency department (ER). The incomplete personal protective equipment (PPE) and poor quality hand washing and hygiene increase the risk of COVID-19 exposure. HCW felt working under pressure also increased the risk of exposure. A work period of more than ten years and attending training can reduce the risk of COVID exposure. The conclusion is there are several factors related to the risk of COVID exposure, including demographic factors, work schedule factors, work stressors, contact history, types of specialized services, PPE, and hygiene behaviors. Abstrak: Penyebaran pandemi COVID-19 yang sangat cepat akan berdampak pada tenaga kesehatan health care workers (HCW) untuk penularan COVID-19. A safety-oriented co-sufferer service system yang berorientasi pada keselamatan menjadi urgen diwujudkan. Faktor risiko pajanan COVID pada petugas kesehatan belum teridentifikasi hingga saat ini. Penelitian ini bertujuan untuk mengidentifikasi faktor risiko pajanan COVID-19 di petugas kesehatan. Penelitian ini melakukan tinjauan sistematis terhadap jurnal-jurnal terpilih sesuai dengan tujuan penelitian. pencarian jurnal dengan kata kunci berdasarkan Masalah (HCW infeksi co-19), intervensi (personal protective equipment (PPE), durasi shift, pekerjaan), Perbandingan (jarak fisik, beban kerja, plasebo), dan Hasil (rasio peluang, rasio risiko) (PICO) dilakukan di Pubmed dan Google Cendekia.Kriteria seleksi mencakup semua jenis literatur yang diterbitkan oleh jurnal peer-review, artikel asli, atau komunikasi singkat yang diterbitkan pada tahun 2019-2020. Peneliti mengekstrak identitas jurnal, penulis, metode, Hasil, dan kesimpulan. ekstraksi data dianalisis dan disajikan secara deskriptif. Penelitian ini mengulas enam artikel. Pendidikan sarjana, pekerjaan dokter, dan usia meningkatkan risiko paparan COVID-19. Faktor beban kerja dan jenis pelayanan yang berhubungan dengan peningkatan risiko terpapar COVID-19 adalah bekerja pada shift malam, bekerja lebih dari 8 jam, pelayanan intubasi, dan bekerja di Instalasi Gawat Darurat (IGD). alat pelindung diri (APD) yang tidak lengkap dan kualitas cuci tangan dan kebersihan. Petugas kesehatan bekerja di bawah tekanan juga meningkatkan risiko pajanan. Masa kerja lebih dari sepuluh tahun dan mengikuti pelatihan dapat mengurangi risiko terpapar COVID.
Comparison of The Histology of Goblet Cells the Intestinal Mucosa Colon Induced by Cayenne Pepper at Doses of 45 mg, 90 mg, 135 mg, 180 mg Usman, Sherly
International Journal Multidisciplinary Science Vol. 5 No. 1 (2026): February: International Journal Multidisciplinary Science
Publisher : Asosiasi Dosen Muda Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56127/ijml.v5i1.2604

Abstract

This study aimed to analyze the effect of cayenne pepper (Capsicum frutescens L.) juice on the histological structure of colonic mucosal crypts and the number of goblet cells in Wistar rats. Cayenne pepper contains capsaicin, flavonoids, and vitamin C, which exhibit both pro-inflammatory and anti-inflammatory properties. Goblet cells play an essential role in maintaining intestinal homeostasis by producing mucin that protects the mucosa from inflammation. This quasi-experimental study employed a post-test only control group design using 20 male Wistar rats divided into one control group and four treatment groups receiving cayenne pepper juice at doses of 45 mg, 90 mg, 135 mg, and 180 mg daily for seven days. On day seven, the rats were terminated, and colon tissues were processed for histological examination using hematoxylin-eosin staining. Observations were conducted under 40× magnification to measure crypt length and count goblet cells. Data were analyzed using the Shapiro–Wilk normality test followed by one-way ANOVA. The results showed significant differences among groups (p<0.05). The 90 mg group exhibited the shortest mean crypt length, while the 135 mg group had the lowest number of goblet cells, indicating greater mucosal damage. In contrast, the 180 mg group demonstrated the longest crypt length and highest goblet cell count, suggesting mucosal repair. These findings indicate that cayenne pepper induces dose-dependent effects on colonic mucosa, with higher doses potentially promoting mucosal regeneration.
Purple Yam (Dioscorea alata) Tuber Improves the Histological Appearance of the Ampulla of the Uterine Tube in a Mouse Model of Endometriosis Makiyah, Sri Nabawiyati Nurul; Usman, Sherly; Adawiyah, Rabiatul
Bioscientist : Jurnal Ilmiah Biologi Vol. 14 No. 1 (2026): March
Publisher : Department of Biology Education, FSTT, Mandalika University of Education, Indonesia.

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33394/bioscientist.v14i1.20007

Abstract

This study aimed to examine the effect of Dioscorea alata ethanol extract (EEDA) on the histological features of the ampulla of the uterine tube in a mouse model of endometriosis. This was a true experimental study with a posttest-only control group design using 30 mice divided into six groups: a normal control group (K), a negative control group (KN) induced with endometriosis, a positive control group (KP) induced with endometriosis and treated with letrozole, and three treatment groups induced with endometriosis and administered EEDA at doses of 50, 250, and 500 mg/kg body weight. The observed parameters included inflammatory cell infiltration, epithelial damage, and fibrosis. Data were analyzed using the Kolmogorov–Smirnov test for normality, which showed that the data were not normally distributed; therefore, the nonparametric Kruskal–Wallis test followed by the Mann–Whitney post hoc test was applied. The results showed that the KN group had the highest scores for inflammatory cell infiltration, epithelial damage, and fibrosis (p < 0.05). Administration of EEDA significantly reduced all three parameters compared with the KN group (p < 0.05), with histological improvement increasing in a dose-dependent manner and the most optimal dose observed at 500 mg/kg body weight. It can be concluded that Dioscorea alata ethanol extract may improve the histological features of the ampulla of the uterine tube through anti-inflammatory and antifibrotic mechanisms at an optimal dose of 500 mg/kg body weight; however, the specific molecular mechanisms still require further verification. These findings indicate the potential of Dioscorea alata ethanol extract as a candidate herbal-based alternative therapy in an experimental model of endometriosis.
Co-Authors Aida Ainun Nisa Aisyah Luthfia Firdasari Akrom Akrom Danantika, Wiriasti Dewi Kartikawati Paramita Dwi Nur Ahsani Ika Setyawati ika setyawati Khotibuddin, Muhammad Noor, Hafni Zuchra Nurusyifa, Hanifah Rabiatul Adawiyah Ratna Indriawati, Ratna RR. Yuningtyaswari Siti Aminah Tri Susila Estri Siti Aminah Tri Susila Estria SN Nurul Makiyah Sri Tasminatun Titiek Hidayati Yustina Andwi Ari Sumiwi Zulkhah Noor