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RELATIONSHIP BETWEEN RENAL STONE LOCATION WITH STONE-FREE RATE AFTER ESWL Siregar, Laudeo Dhanaba; Warli, Syah Mirsya
Indonesian Journal of Urology Vol 24 No 1 (2017)
Publisher : Indonesian Urological Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32421/juri.v24i1.253

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Objective: This study aims to evaluate the relationship between stone location and stone location in kidney stone to the stone-free rate after Extracorporeal Shock Wave Lithotripsy (ESWL) procedure. Material & method: This is a non-experimental research using descriptive analytic method with retrospective study design that takes data from patient medical record diagnosis of urinary tract stones and ESWL action from January 2011 until December 2013 in the Department of Surgery Division of Urology General Hospital H. Adam Malik, Medan. Results: It was found that if the size of the stone only is the only factor that counts in patients who get a urinary tract stones ESWL therapy, it is not found a statistically significant relationship. Stone location plays an important role in the incidence of stone-free patients with urinary tract stones ESWL therapy. Conclusion: ESWL therapeutic efficacy in the treatment of patients with kidney stones is not only determined by the size and location of the stone, but is also determined by the number of stones, stone composition, frequency ESWL is used, and the thickness of the skin of the patient.
THE EFFECT OF ANDROGEN DEPRIVATION THERAPY ON THE LIPID PROFILE AND BLOOD GLUCOSE LEVEL IN PROSTATE CANCER PATIENTS IN ADAM MALIK GENERAL HOSPITAL MEDAN Irawan, Willi; Warli, Syah Mirsya
Indonesian Journal of Urology Vol 24 No 2 (2017)
Publisher : Indonesian Urological Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32421/juri.v24i2.304

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Objective: The aim of this study is to observe the effect of Androgen Deprivation Therapy (ADT) on patients with advanced stage of prostate cancer on the lipid profile and blood glucose level. Material & Methods: This is a descriptive cross-sectional study and include the prostate cancer patients which were admitted to Urology Policlinic in Haji Adam Malik General Hospital, Medan from June 2014 – June 2015 and also received ADT. Results: From June 2014 – June 2015, a total of 25 prostate cancer patients receiving ADT was included in this study with an average age of 67.08 ± 7.48 years old. The median prostate specific antigen (PSA) level of this group of patients is 19.6 ng/mL and the lowest and highest value of 3.4 and 278 ng/mL respectively. ADT administration is found to cause a significant elevation of 2-hour postprandial blood glucose (121.12 ± 21 mg/mL vs 134.64 ± 33.35 mg/mL, p-value=0.011) and Glycosylated hemoglobin (5 ± 0.5% vs 5.5 ± 0.79%, p-value=0.000) (HbA1c) after 6 months of therapy. Additionally, ADT administration within 3 and 6 months of duration had also significantly increased triglyceride (TG) level when compared to before treatment (104.4 ± 38.67 vs 131.2 ± 32.27 vs 127 ± 33.43 respectively, p-value=0.005). Conclusion: ADT treatment in prostate cancer patients increase triglyceride levels after 3 and 6 months of treatment followed by 2-hour postprandial blood glucose and HbA1C levels after 6 months of the treatment.
PROGNOSTIC FACTORS OF RENAL CANCER Kurnia, Riyan Adi; Warli, Syah Mirsya; Siregar, Ginanda Putra
Indonesian Journal of Urology Vol 24 No 2 (2017)
Publisher : Indonesian Urological Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32421/juri.v24i2.326

Abstract

Objective: Course of the disease of kidney cancer may be unpredictable. For example, between 4.2–7.1% of patients with tumours ≤4 cm that are usually slow-growing may have metastases at diagnostic and are at an elevated risk of disease-specific mortality. Conversely, as many as 40% of patients with lymph node metastases were diagnosed at nephrectomy are alive 5 year after surgery. Several approaches have been proposed to help predict the course of disease of kidney cancer and to distinguish between poor and favourable risk patients. In this study, we review the existing prognostic factors and compared with established prognostic models. Material & methods: This is an analytic descriptive study of all kidney cancer patients treated at Haji Adam Malik Hospital between 2011 and 2015. Individual patient data was collected from medical record and compiled. Results: The number of samples analyzed in this study were 38 patients. We found seven patients remain alive of the entire sample. From the results of the univariate test, the factors that have a significant relationship with the mortality rate were low KPS (<80), weight loss, and nephrectomy. From the results of multivariate analysis, nephrectomy is the only prognostic factor in patients with kidney cancer. Mortality rate was 0.056x lower in patients who underwent nephrectomy compared with patients who did not underwent nephrectomy. Conclusion: Despite the high mortality rate that is found in this study, nephrectomy still has a place in kidney cancer management, even in patients with advanced stage.
IATROGENIC URINARY TRACT TRAUMA IN OBSTETRICS AND GYNECOLOGIC SURGERIES AT H. ADAM MALIK GENERAL HOSPITAL MEDAN Djufri, Teguh Risesa; Warli, Syah Mirsya
Indonesian Journal of Urology Vol 26 No 2 (2019)
Publisher : Indonesian Urological Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32421/juri.v26i2.441

Abstract

Objective: Urinary tract iatrogenic trauma in abdominal or pelvic surgery may cause morbidity, mortality, or even medico-legal problems. The close embryonic, as well as anatomical relationship between urinary tract and genital organs, may be a predisposition for urinary tract trauma, especially ureter and bladder, in obstetrics and gynecology surgeries. This research aimed to evaluate the incidence of iatrogenic urinary tract trauma in obstetrics and gynecology surgeries. Material & Methods: This was a descriptive retrospective research. This research was conducted at Urology Division of Department of Surgery at H. Adam Malik General Hospital, Medan, from February to June 2016. Total sampling method was used. Data were collected from medical records of patients who had iatrogenic urinary tract trauma due to obstetrics and gynecology surgeries at H. Adam Malik General Hospital from January 2011 to December 2015. Parameters that were evaluated included patient characteristics, the type of obstetrics and gynecology procedure that was conducted, the type of urinary tract trauma, and the type of urologic procedure conducted. Data were registered and analyzed using statistical software SPSS version 22. Results: There were 25 patients with 28 incidences of iatrogenic urinary tract trauma, which consisted of 12 iatrogenic ureteral trauma and 16 iatrogenic bladder trauma, out of all patients who underwent obstetrics and gynecologic surgeries at H. Adam Malik General Hospital, Medan, from January 2011 to December 2016. The youngest patient was 19 years old, while the oldest patient was 78 years old. Mean age of patients was 46.48 years (SD ± 11.6). The age group with the most iatrogenic urinary tract trauma was between 26-45 years old, which consisted of 12 patients (48%). Gynecologic patients had the most iatrogenic urinary tract trauma, which was experienced by 23 patients (92%). The most common diagnosis was ovarian cancer. Hysterectomy was the most common procedure to cause iatrogenic urinary tract trauma, as was found in 23 patients (92%). All patients who were found with iatrogenic bladder trauma (15 patients; 60%) underwent bladder repair. Conclusion: Gynecologic procedure, especially hysterectomy, was the most common cause of iatrogenic urinary tract trauma. Bladder repair procedure was the most common procedure performed on patients who were found with iatrogenic urinary tract trauma. 
Blood cell count is not a significant predictor of survival in bladder cancer after radical cystectomy Andy, Andy; Prapiska, Fauriski Febrian; Siregar, Ginanda Putra; Warli, Syah Mirsya; Sihombing, Bungaran
Universa Medicina Vol. 40 No. 2 (2021)
Publisher : Faculty of Medicine, Universitas Trisakti

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18051/UnivMed.2021.v40.151-159

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BackgroundRadical cystectomy (RC) is the gold standard treatment for muscle-invasive bladder carcinoma. A predictive factor is needed for the aggressive approach as it could lead to overtreatment. Elevated blood cell count (BCC) markers are reported to have a significant association with poor outcomes in several types of malignancy. Neutrophil-to-lymphocyte-ratio (NLR) and platelet-to-lymphocyte ratio (PLR) are well-known inexpensive and effective representative markers of inflammatory conditions. This study aimed to determine the BCC as a predictive factor of overall survival (OS) in patients with bladder carcinoma (BC) after RC. MethodsA retrospective cohort study was conducted involving 26 patients who had undergone RC. The demographic characteristics and BCC markers such as hemoglobin (Hb). NLR, PLR and lymphocyte/monocyte ratio (LMR) were collected. The patients were categorized based on the BCC marker value (³ median and < median). Kaplan–Meier survival analysis was done to determine overall survival (OS) on BCC markers. The association between patient demographics and one-year survival was also determined using Mantel-Cox (Log-rank) method. ResultsAmong the 26 patients, the mean age was 55.6 ± 12.9 years. On univariate analysis, none of the demographic characteristics was found to be a significant predictor of one-year and overall survival (p>0.05). Hemoglobin, NLR, PLR and LMR were not significant predictors of one-year survival and OS (p>0.05). ConclusionsThe BCC was not a significant predictive factor of survival in patients with bladder cancer after radical cystectomy.
Prevalensi Disfungsi Ereksi pada Pesepeda Usia 25-55 Tahun di Kota Medan Muhammad Fahmi Ikram; Syah Mirsya Warli; Fauriski Febrian Prapiska; Dhirajaya Dharma Kadar
Syntax Literate Jurnal Ilmiah Indonesia
Publisher : Syntax Corporation

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (206.598 KB) | DOI: 10.36418/syntax-literate.v7i1.6032

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Latar belakang. Disfungsi ereksi merupakan penyakit seksual dan menimbulkan dampak yang signifikan dalam mempengaruhi kualitas hidup seorang pria. Disfungsi ereksi sendiri didefinisikan sebagai ketidakmampuan yang konsisten atau berulang untuk mencapai dan / atau mempertahankan ereksi penis yang cukup untuk kepuasan seksual, termasuk kinerja seksual yang memuaskan. Secara global, prevalensi disfungsi ereksi diperkirakan sekitar 3–76,5%. Eropa merupakan benua dengan prevalensi disfungsi ereksi tertinggi (10-76,5%), diikuti Asia (8-71,2%), Oceania (40,3-60,69%), Afrika (24-58,9%), Amerika Utara (20,7-57,8), dan yang terendah terdapat di Amerika Selatan (14-55,2). Pada studi yang dilakukan di Kota Jakarta didapati prevalensi disfungsi ereksi di Kota Jakarta pada 255 sampel pria berumur 20-80 tahun sebanyak 36,5 % dengan rincian 22,3% pada disfungsi ereksi ringan, 13,7% ringan ke sedang, 3,1% sedang, dan 0,8% berat. Faktor-faktor yang dapat menyebabkan disfungsi ereksi bersifat multifaktoral, diantaranya Diabetes Melitus, Hipertensi, peningkatan usia, penyakit jantung, dan penggunaan obat-obatan yang mempengaruhi fungsi ereksi. Namun, penurunan aliran darah dan neuropati saraf pudendal karena kompresi di perineum pada saat bersepeda merupakan faktor risiko yang juga dapat menyebabkan gangguan pada fungsi ereksi sehingga berujung pada disfungsi ereksi. Tujuan. Penelitian ini bertujuan untuk mengetahui prevalensi pada pesepeda dengan usia 25-55 di Kota Medan. Metode. Penelitian yang dilakukan bersifat deskriptif dengan desain cross sectional. Sampel pada penelitian ini adalah pesepeda di Kota Medan yang memenuhi kriteria inklusi dan eksklusi. Teknik pengambilan data adalah Consecutive sampling. Hasil. prevalensi DE pada pesepeda usia 25-55 tahun di kota medan sebesar 20% yang dinilai dengan skoring IIEF-5 pada total sampel 95 pesepeda (100%). Kesimpulan. terdapat sebesar 20% kejadian DE pada pesepeda usia 25-55 tahun di kota Medan.
Perubahan tingkat kekerasan ereksi pada pasien BPH paska pemberian α1A- adrenoreceptors antagonis di RSUP H. Adam Malik Medan Muhammad Eka Agusfansyah; Syah Mirsya Warli; Bungaran Sihombing
Majalah Kedokteran Nusantara The Journal Of Medical School Vol 45, No 3 (2012): The Journal of Medical School
Publisher : Fakultas Kedokteran USU

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Background : Lower urinary tract infection (LUTS) at benign prostate hyperplasia (BPH) patient commonly followed by sexual dysfunction which include erectile dysfunction, at last study there was relation between LUTS/BPH and erectile dysfunction.1a-adrenoceptors antagonists (Tamsulosin) is very selective adrenoceptor •1 antagonist. These drugs block a adrenaceptor1a the prostate which further led to improvement of LUTS symptoms and also blocked the action of noradrenaline at the level1a receptors on smooth muscle of the corpus cavernosum to enhance and improve erectile function. The purpose of this study was to determine changes in the level of erection hardness in patients with BPH after administration •1a-adrenoceptors antagonists for 1 month.Methods : This research is an experimental study. Anamnesis directly performed on 50 subjects who met the inclusion criteria and did not meet the exclusion criteria. To assess the degree of erection hardness using a special instrument that used erection hardness score (EHS), where EHS is a diagram of the quality of erection hardness which consisted of grade 1 to 4. Patients will be assessed level of erection hardness using EHS before and after the intervention for 1 month with •1a-adrenoceptors antagonistsResult : Based on statistical analysis, after administration of •1a-adrenoceptors antagonists found there was a significant increase in the value of EHS compared with before intervention, with P value = 0.001 (• = 0.005 CI = 95%). 36 subjects with EHS 2 before intervention, 16 subjects turned into EHS 3 after the intervention. 13 subjects with EHS 3 before the intervention, after the intervention did not change the value of EHS. One subject with EHS 4 before intervention also did not change after the intervention.Conclusion : This study proved that •1a-adrenoceptors antagonists can improve erectile dysfunction in patients with BPH. Keywords : BPH; erectile dysfunction; •1a-adrenoceptors antagonists; LUTS; EHS
Outcome benefits to transurethral resection of the prostate in patients with benign prostatic hyperplasia at Medan regional hospital Richman Patandung; Syah Mirsya Warli
JKKI : Jurnal Kedokteran dan Kesehatan Indonesia JKKI, Vol 12, No 2, (2021)
Publisher : Faculty of Medicine, Universitas Islam Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20885/JKKI.Vol12.Iss2.art6

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Background: Benign prostatic hyperplasia (BPH) is a pathologic process that cause of lower urinary tract symptoms (LUTS) in aging men. Transurethral resection of the prostate (TURP) is still the current gold standard of BPH treatment. International Prostate Symptoms Score (IPSS) and the quality of life (QoL) index are used for assessing the TURP results.Objective: This study would like to show the benefits outcome of TURP in patients with BPH evaluated with IPSS score and QoL index in Medan regional hospital.Methods: This research is a retrospective study of BPH patients that is treated with TURP at Universitas Sumatera Utara Hospital from September 2019 – August 2020. Patients will be divided into 2 groups, group 1 with patients who have a prostate size <80 grams and the second group with a prostate size> 80 grams. All patients who were included in this study were assessed for their complaints using the IPSS and QoL index before and after taking an operation. Statistical analysis was performed using independent t test and Mann Whitney test. The data were significant if the p value < 0.05. Results: There are 60 patients enrolled in this study that treated with TURP. The mean age of patients in the group 1 was 69.57 ± 7.698 years and 69.84 ± 5.893 years in the group 2. There is no significant difference between group 1 and group 2 in postoperative IPSS and QoL results (p >0.05). Conclusion: TURP procedure is preferable option of BPH for patients in any prostate size.
Differences of Lower Urinary Tract Symptoms Degree In Benign Prostatic Hyperplasia Patients With and Without Diabetes Mellitus Clarissa, Jeannis; Warli, Syah Mirsya; Dhirajaya Dharma Kadar; Nurfida Khairina Arrasyid
Journal of Endocrinology, Tropical Medicine, and Infectious Disease (JETROMI) Vol. 3 No. 3 (2021): Journal of Endocrinology, Tropical Medicine, and Infectious Disease (JETROMI)
Publisher : TALENTA Publisher, Universitas Sumatera Utara

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (544.383 KB) | DOI: 10.32734/jetromi.v3i3.6415

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Background. Benign Prostatic Hyperplasia (BPH) is a benign tumor that most often occurs in men. Many risk factors could cause BPH, one of which is diabetes mellitus (DM). Diabetes mellitus (DM) is a metabolic disease, characterized by hyperglycemia. Method. This study was conducted at the Urology Polyclinic of the Universitas  Sumatera Utara Hospital from August to September 2019. A total of 102 patients diagnosed with BPH were registered by cross-sectional study approach. Detailed medical history and physical examination were performed for all patients to diagnose BPH. While the diagnosis of DM was according to patient history or diabetic-medicine use. International Prostate Symptom Score (IPSS) were completed by all patients to obtain a LUTS degree. Result. From a total of 102 patients diagnosed with BPH there were 97 patients were selected. The mean age of patients was 70.43 ± 7.52 year (range 50-88 year) and the total IPSS score was 17.55 ± 6.55. DM patients were more likely to report severe LUTS and the symptom score evaluated with IPSS was significantly higher than in non non-DM group: 21.69 ± 5.41 vs 16.70 ± 6.41 (p=0.005). For the IPSS subscores, the DM group also show higher storage: 8.38 ± 4.57 vs 5.88 ± 3.72 (p = 0.02), voiding: 9.69 ± 2.47 vs 8.14 ± 3.21, (p= 0.039) and post micturition: 3.63 ± 1.26 vs 2.69 ± 1.744, (p= 0.045) symptoms significantly. Conclusion: Benign Prostatic Hyperplasia patients with DM manifested more severe lower urinary tract symptoms. Storage, voiding, post micturition, and urgency symptoms were also greater.
Prevalence and Correlated Factors of Urinary Incontinence in Geriatrics Purba, Adriel John Junior; Mirsya Warli, Syah; Dharma Kadar, Dhirajaya; Charani Eyanoer, Putri
Sumatera Medical Journal Vol. 6 No. 2 (2023): Sumatera Medical Journal (SUMEJ)
Publisher : Talenta Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32734/sumej.v6i2.11030

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Background: Urinary incontinence is involuntary or uncontrollable urine passing. This is very disruptive, it causes a lot of problems and is often seen as an embarrassing thing. The prevalence of urinary incontinence was found to increase with age. Objective: This research aimed to determine the prevalence and factors associated with the incidence of urinary incontinence in geriatric patients at the Haji Adam Malik General Central Hospital and the University of North Sumatera Hospital. Methods: This type of research is an analytic observational study with a cross-sectional design. The research sample is determined by consecutive sampling technique using a questionnaire as primary data. Results: Out of 100 respondents, 22 geriatric patients experienced urinary incontinence, with the majority experiencing moderate severity and stress urinary incontinence. Based on bivariate analysis using chi-square found gender (p=0.617), age (p=0.617), overweight (p=<0.01), diabetes mellitus (p=<0.01), hypertension (p=0.01), history of chronic cough (p=<0.01), history of pelvic surgery (p=<0.01), and history of vaginal delivery (0=0.055). Conclusion: In this study, the risk factors associated with urinary incontinence are overweight, diabetes mellitus, hypertension, and a history of chronic cough while risk factors that are not found to be associated in this study are age, sex, and history of vaginal delivery.