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All Journal Jurnal Pendidikan dan Pembelajaran Khatulistiwa (JPPK) Jurnal Farmasi Klinik Indonesia Jurnal Farmasi Galenika (Galenika Journal of Pharmacy) Jurnal Surya Medika Majalah Farmaseutik Jurnal Pendidikan Matematika (JUDIKA EDUCATION) JFIOnline Indonesian Journal of Global Health research Jurnal Farmasi Sains dan Terapan (Journal of Pharmacy Science and Practice)
Widyati, Widyati
Rumah Sakit Angkatan Laut Dr. Ramelan, Surabaya
Biochemistry, Genetics & Molecular Biology Chemistry Decision Sciences, Operations Research & Management Education Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Mathematics Medicine & Pharmacology Nursing Public Health Other

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Efektivitas dan Keamanan Furosemid Continuous Infusion Dosis 10 dan 20 mg/jam pada Pasien Penyakit Ginjal Kronik Kondisi Fluid Overload Syndrome disertai Hipoalbumin di RSUD Abdul Wahab Sjahranie Setiadi, Diga Albrian; Widyati, Widyati; Yakti, Kuntjoro
Jurnal Farmasi Sains dan Terapan (Journal of Pharmacy Science and Practice) Vol. 7 No. 1 (2020): Februari
Publisher : Faculty of Pharmacy, Widya Mandala Surabaya Catholic University, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33508/jfst.v7i1.2390

Abstract

Furosemide continuous infusion is the first choice drug in overcoming the condition of Fluid overload syndrome with hypoalbuminemia in patients with Chronic Kidney Disease (CKD). However, in these conditions, the dose of furosemide used by clinicians is between 10 and 20 mg/hour. No studies have compared the effectiveness and safety of different doses of furosemide. This study aimed to evaluate the effectiveness and safety of 10 and 20 mg/hour furosemide given in continuous infusion in CKD patients with fluid overload syndrome with hypoalbuminemia. The method is a Single-blind, Randomized Clinical Trial conducted during the period of February-April 2017 in the inpatient ward of Abdul Wahab Sjahranie Hospital. Data processing was carried out by statistical analysis, Two Independent T-Test parametric test for data that normally distributed and those that did not correlate with each other, whereas for data that not normally distributed and those that did not correlate with each other, non-parametric test Mann Whitney and Wilcoxon were used. Outcomes studies were 24-hour urine volume, shortness of breath, duration of oxygen consumption, Ronchi and safety of therapy seen from drug side effects (hypotension, hyperuricemia, hyperglycemia, hyponatremia, hypokalemia). The results of the study, 34 patients with CKD with fluid overload syndrome with hypoalbuminemia (2.5-3.0 g/dL) were registered. On the effectiveness of therapy, there was no significant difference in 24-hour urine volume (P = 0.324; P> 0.05; 95%; CI=714.6-1017.8 ml group 1; CI=818.0-1113.2 ml group 2), shortness of breath (P = 0.781; P> 0.05; 95 % CI=0.68-1.32 group 1; CI=0.72-1.40 group 2), duration of oxygen use (P = 0.363; P> 0.05; 95% CI=1.34-2.66 day group 1; CI=1.72-3.10 day group 2), Ronk (P = 0.692; P> 0.05 ) and the absence of drug adverse events (P = 1.000; P> 0.05) between the two groups. In conclusion, the dose of 10 and 20 mg/hour furosemide has the same
The Practice of Prolonging Meropenem Infusion: A Narrative Review of Literatures Over the Last Decade: The Practice of Prolonging Meropenem Infusion: A Narrative Review of Literatures Over the Last Decade Fauzi, Rifani; Widyati, Widyati; Sari, Ika Puspita
Jurnal Surya Medika (JSM) Vol. 10 No. 1 (2024): Jurnal Surya Medika (JSM)
Publisher : Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33084/jsm.v10i1.7162

Abstract

Background: The emergence of Antimicrobial Resistance (AMR) has forced clinicians and medical professionals to implement a strict Antimicrobial Stewardship policy. One of the pillar of Antimicrobial Stewardship is by optimizing the use of antibiotic agents. Beta-lactams demonstrate a time-dependent effect in combating bacteria. Since it is pharmacodynamically supported, a prolonged exposure via intravenous administration could be a feasible strategy to maximize the bactericidal effect. Meropenem, a beta-lactam antibiotic of carbapenems sub-class, also falls into the category above. However, there are questions to be answered regarding its stability, compatibility, safety, and clinical outcomes superiority compared to the standard intermittent infusion, before we can determine its effectiveness to be delivered as prolonged or extended infusion. Aims: This article would like to review literatures regarding the rationale behind the practice of prolonging meropenem infusion from the last decade. Method: For this narrative review we utilized articles extracted from Cochrane Library, ScienceDirect, and SageJournals databases from the last ten years. We also added complementary related articles from UpToDate®. Selected articles were limited to those published in english. Inclusion criteria specifically only including related articles to the practice of prolonging meropenem infusion on adult patients. A total of 18 articles were reviewed for the synthesis of this narrative review. Conclusion: Meropenem is eligible for prolonged infusion protocol since it is theoretically supported, adequate in stability, less concern for incompatibility, and potentially can provide better clinical outcomes compared to standard intermittent infusion.
Perbandingan Pembelajaran Matematika Berbasis Deep Learning dan Pembelajaran Konvensional dalam Mengembangkan Penalaran Kritis Siswa Ismiarti, Ismiarti; Nilawati, Sastri; Rusyanih, Yanih; Widyati, Widyati; Rahmiwati, Puji
Jurnal Pendidikan Matematika : Judika Education Vol. 9 No. 1 (2026): Jurnal Pendidikan Matematika: Judika Education
Publisher : Institut Penelitian Matematika, Komputer, Keperawatan, Pendidikan dan Ekonomi (IPM2KPE)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31539/vha0h220

Abstract

This study aims to compare the effectiveness of Deep Learning-based mathematics instruction and conventional instruction in developing seventh-grade students’ critical reasoning skills. The method used was a qualitative comparative approach with a multiple case study design involving two classes and two mathematics teachers selected purposively, with data collected through observation, interviews, and documentation and analyzed using Miles and Huberman’s thematic analysis model. The findings indicate that Deep Learning-based instruction is more effective in promoting students’ reflective thinking, strategy evaluation, and concept generalization compared to conventional instruction, which tends to emphasize procedural mastery. In conclusion, Deep Learning-based instruction contributes more significantly to the development of students’ critical reasoning skills; however, its effectiveness is influenced by the quality of teacher facilitation and task design, therefore the integration of both approaches is recommended to achieve optimal learning outcomes. Keywords: Critical Reasoning; Deep Learning; Mathematics Learning; Conventional Learning.
Co-Authors Agung Endro Nugroho Arrang, Sherly Tandi Fauzi, Rifani Giyantolin, Giyantolin Harijono, Pandu Ika Puspita Sari Ismiarti, Ismiarti Lukman Hakim Nilawati, Sastri Putri, Cyndi Yulanda Rahmatullah, Daril Rahmatullah, Daril Rahmiwati, Puji Regina Regina Rusyanih, Yanih Sari, Juwita Permata Setiadi, Diga Albrian Setiawan, Stefanie Simorangkir, Timbul Partogi Haposan Soediatmoko, Soediatmoko Subiakto, Yuli Sutapa, Y. Gatot Yakti, Kuntjoro