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All Journal Jambi Medical Journal : Jurnal Kedokteran dan Kesehatan Biomedika Indonesian Journal of Medicine Journal Orthopaedi and Traumatology Surabaya (JOINTS) The Hip and Knee Journal Indonesian Journal of Biomedicine and Clinical Sciences

Utomo, Pamudji

Unknown Affiliation

Author-ID : 1186627

Biochemistry, Genetics & Molecular Biology Decision Sciences, Operations Research & Management Education Health Professions Immunology & microbiology Medicine & Pharmacology Neuroscience Public Health

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EFEKTIVITAS KEPEKATAN LARUTAN SODIUM HYPOCHLORITE TERHADAP BIAKAN KUMAN STAPHYLOCOCCUS AUREUS Effendi, Fajar Ivan; Ernawan, Rieva; Utomo, Pamudji; Mariyanto, Ismail; Santoso, Asep
JAMBI MEDICAL JOURNAL "Jurnal Kedokteran dan Kesehatan" Vol. 9 No. 2 (2021): JAMBI MEDICAL JOURNAL Jurnal Kedokteran Dan Kesehatan
Publisher : FAKULTAS KEDOKTERAN DAN ILMU KESEHATAN UNIVERSITAS JAMBI

Abstract Musculoskeletal infections have complex complications, making them a challenge. Most countries have experienced Staphylococcus aureus resistance to methicillin by 25% and some even over 50%. Dakin solution (0.050% to 0.025%) can be used as irrigation, cleansing, and used on moist gauze for the management or prevention of skin or tissue infections. This study aims to determine the lowest concentration level of Dakin solution / sodium hypochlorite which is the safest and most effective in the culture of Staphilococcus aureus. This research is an analytical experimental research, with the concept of comparing the Staphylococcus aureus ATCC 25923 germ cultures which are treated in the form of giving dakin solution / sodium hypochlorite 0.050%, 0.025%, 0.0125% and control using 0.9% NaCl. Observation of the effectiveness is done by measuring the formed inhibition zone. The concentration of 0.025% gives a fairly good disinfectant effect with moderate inhibition power, the concentration of 0.050% gives a good disinfectant effect with a strong inhibitory power while the concentration of 0.0125% does not have a disinfectant effect, this is the same as the 0.9% NaCl control solution. The zone of inhibition in the staphylococcus aureus bacteria culture ATCC 25923 at concentrations of 0.025% and 0.050% still gave a stable effect until evaluation within 2x24 hours (48 hours). Keywords : Dakin solution, Sodium hypoclorite, resistor zone, Staphylococcus aureus.

Osteokondroma Raksasa Pada Rami Pubis: Laporan Kasus Idulhaq, Mujaddid; Utomo, Pamudji; Jiwandono, Bayu Sakti; Tulandi, M qathar RF Tulandi
JAMBI MEDICAL JOURNAL "Jurnal Kedokteran dan Kesehatan" Vol. 8 No. 2 (2020): JAMBI MEDICAL JOURNAL Jurnal Kedokteran Dan Kesehatan
Publisher : FAKULTAS KEDOKTERAN DAN ILMU KESEHATAN UNIVERSITAS JAMBI

ABSTRAK Pendahuluan Osteokondroma adalah tumor tulang jinak yang paling umum. Osteokondroma merupakan malformasi perkembangan daripada neoplasma sejati.Osteokondroma biasanya mempengaruhi tulang yang berkembang oleh osifikasi endokondral dan jarang berasal dari tulang yang berkembang secara osifikasi intramembran seperti tulang rami pubis, skapula, klavikula, dan tulang rusuk. Objektif Makalah ini dimaksudkan untuk menyajikan kasus osteokondroma pubis yang jarang terjadi dan mengevaluasi hasil setelah eksisi luas. Kasus Seorang pria 34 tahun dengan benjolan di daerah selangkangan kanan mengeluh selama 10 tahun. Di RSO Prof Soeharso, pasien menjalani eksisi lebar ramus pubis kanan, di mana banyak struktur berbahaya yang harus dihindari. Kami mendapatkan seluruh jaringan tumor dengan diameter 12 sentimeter. Menurut Konferensi Klinikopatologi tumor disimpulkan sebagai osteokondroma. Lokasi tumor dan presentasi klinis jarang terjadi. Tumor ini tidak memiliki keterlibatan viseral atau vaskular meskipun lesi tersebut sangat dekat dengan banyak struktur vital pada ramus pubis superior. Hasil Setelah 1 tahun evaluasi, kondisi klinis pasien baik. Pasien tidak merasakan keluhan apapun, tidak ada tanda-tanda kambuh, dan tidak ada komplikasi pada luka operasi. Kesimpulan Kami telah melakukan eksisi ekstensif tumor di ramus pubis pria berusia 34 tahun. Hasil pemeriksaan histopatologi sesuai dengan gambaran osteokondroma. Osteokondroma yang muncul dari panggul adalah presentasi yang tidak biasa yang harus diingat sebagai diagnosis banding saat mengevaluasi pasien dengan massa di panggul.

PRINCIPLE OF REHABILITATION & COMPLICATION PREVENTION AFTER MUSCULOSKELETAL TRAUMA Utomo, Pamudji; Akbar, Hillan
JAMBI MEDICAL JOURNAL "Jurnal Kedokteran dan Kesehatan" Vol. 9 No. 2 (2021): JAMBI MEDICAL JOURNAL Jurnal Kedokteran Dan Kesehatan
Publisher : FAKULTAS KEDOKTERAN DAN ILMU KESEHATAN UNIVERSITAS JAMBI

Rehabilitation plays a major role to maximize outcome and prevent complications following musculoskeletal trauma and its interventions. It is reported in several studies that mortality risk in patients not receiving rehabilitation was higher compared with patients who received one. The key principles include adequate pain management, anti-infection measures, early ambulation and physical therapy, establishing proper milestones and goals, well-communicated multi-disciplinary approach, and the establishment of standardized and personalized treatment protocol. Early mobilization is supported, as long as wound healing has been taken into consideration. Holistic approach to ensure both physical and psychosocial well-being is recommended, along with special care for geriatric and paediatric populations. Furthermore, alternative medicines such as acupuncture and meditation are currently gaining popularity and subsequently advocated as adjunct therapies.

RADIOSCAPHOLUNATE (RSL) FUSION ON SECONDARY OA WRIST WITH NEGLECTED DISLOCATION RADIOCARPAL JOINT AND CONTRACTURE DUE TO ENTRAPMENT OF SUPERFICIAL FLEXOR TENDON INDEX FINGER OF LEFT HAND Rian, Rahmad; Hadinoto, Seti Aji; Sumarwoto, Tito; Utomo, Pamudji; Tulandi, M qathar RF Tulandi
JAMBI MEDICAL JOURNAL "Jurnal Kedokteran dan Kesehatan" Vol. 9 No. 2 (2021): JAMBI MEDICAL JOURNAL Jurnal Kedokteran Dan Kesehatan
Publisher : FAKULTAS KEDOKTERAN DAN ILMU KESEHATAN UNIVERSITAS JAMBI

ABSTRACT Background: When pain, deformity and instability compromise wrist function, wrist stabilization by means of fusion is a procedure of recognized validity. The goal of wrist arthrodesis is to provide the patient with a stable wrist for power grip and the predictable relief of pain while sacrificing wrist motion. The radioscapholunate (RSL) fusion is one of salvage procedure indicated in the case of traumatic or degenerative osteoarthritis of the radiocarpal joint, involving the lunate facet of the radius. RSL-fusion reduced total wrist motion (3 MC/Rad) in the F/E axis to an average of 49% of F/E in the unfused wrist but preserves midcarpal joint motion while alleviating pain. Case Report: We report a 43-year-old male patient with pain on his left wrist. 10 months before admission, he felt down from stairs with his left hand bear his body weight. He broke his wrist and got surgery at that time. Because still feel pain and his index finger can’t fully extensed, he brought to Soeharso orthopaedic hospital. Here, we have done RSL-fusion using cross pinning K-Wire to reduce pain, distal scapoid excision to optimizing radial angulation and release superficial flexor tendon index finger of left hand. Discussion: With Secondary OA of left wrist post traumatic with neglected radiocarpal dislocation and superficial flexor tendon contracture due to entrapment index finger of left hand post RSL-fusion, distal scapoid excision and release contracture can reduce pain at radiocarpal joint and improve range of movement. Conclusion: The goal of Radioscapholunate (RSL) fusion is to optimizing wrist motion and strength while minimizing or eliminating pain Keywords: Radioscapholunate fusion, partial wrist arthrodesis, limited wrist fusion, reduce pain

Distal Femur Morphological Discrepancy Compared with Total Knee Arthroplasty Implants in Indonesia Sentana, Okkie Mharga; Utomo, Pamudji
The Hip and Knee Journal Vol 4, No 2 (2023): August
Publisher : Indonesian Hip and Knee Society (IHKS)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46355/hipknee.v4i2.153

The prosthesis of knee joint in total knee arthroplasty (TKA) can give better fixation and stabilization if it’s chosen properly. Most of prosthesis have been designed to be compatible with western population, not for Asian population. Whether the implant size need to be adjusted with ethnics and gender still being a controversy. Aim to define whether the morphology of Distal Femur, among men and women in Indonesia have discrepancy and to assess compatibility of the prosthesis size in Indonesia. This study was a descriptive cross-sectional study that conducted at Prof. Dr. R Soeharso’s Orthopaedic Hospital – Surakarta, Indonesia, using purposive quota sampling methods. The inclusion criteria MRI knee joint of men and women (age ≥ 18 years old) which have soft tissue injury of knee joint. The morphological measurement of Distal Femur with the use of certain Software. Then, the data were analyzed with SPSS ver.17 using independent T-Test. The results among 130 patients, we found that Women’s fML were narrower than men. While the ratio aspect of femur implants compared to gender, showed that it was not compatible for men, but more compatible for women. The conclusion there is discrepancy of morphological size of Distal Femur among men and women in Indonesia. It causes incompatibility of using TKA implant in men patients in Indonesia, which more suitable for women size.

Clinical Characteristic of Patients Underwent Bone Mineral Density Examination in Prof. Dr. R. Soeharso Orthopaedic Hospital in 2022-2023: A Cross-Sectional Study Prijosedjati, R. Andhi; Utomo, Pamudji; Sabariyah, Leli; Fauzi, Ahmad
(JOINTS) Journal Orthopaedi and Traumatology Surabaya Vol. 13 No. 1 (2024): April 2024
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/joints.v13i1.2024.1-11

Background: In Indonesia, osteoporosis affects roughly 23% of men and women aged 50-70 and a staggering 53% of those over 70. Understanding the characteristics of patients undergoing bone mineral density (BMD) examinations is crucial for developing better strategies for prevention, diagnosis, and treatment. This study investigates the characteristics of patients who had BMD examinations at the Prof. Dr. R. Soeharso Orthopaedic Hospital. Methods: A cross-sectional study was conducted at Prof. Dr. R. Soeharso Orthopaedic Hospital from April 2022 to April 2023, using a total sampling approach and data extracted from digital medical records. The variables included age, gender, body mass index (BMI), BMD T-score from the lumbar spine, hip, and forearm, frequency and location of fragility fracture (FF), osteoporosis frequency, and fracture risk assessment (FRAX) score for major osteoporotic fracture (MOF) and hip fracture. Patients with incomplete data were excluded. Results: This study involved 168 patients, mainly women (83%) and men (17%). Most (81.5%) were aged 50-74, with osteoporosis affecting 29.2% and severe osteoporosis affecting 60.7%. The spine was the most common site of FF (88.2%). Osteoporosis severity correlated with higher BMI (p<0.05). FRAX scores for MOF and hip fractures were mostly in the low-risk category. Conclusions: A high prevalence of osteoporosis and severe osteoporosis among women, particularly those in the age of 50 to 74 years, and higher BMI was correlated with greater severity of osteoporosis. FF was found more common among women with the spine as the most frequently affected site.

Umbilical cord mesenchymal stem cells and their secretome in peripheral nerve regeneration: a narrative review promising therapeutic strategy Sumarwoto, Tito; Hadinoto, Seti Aji; Romaniyanto; Rhatomy, Sholahudin; Utomo, Pamudji; Idulhaq, Mujaddid; Santoso, Asep; Suroto, Heri
Indonesian Journal of Biomedicine and Clinical Sciences Vol 57 No 4 (2025)
Publisher : Published by Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/inajbcs.v57i4.24055

The injuries of peripheral nerves remain a substantial clinical challenge because of their limited regenerative capacity, the complexity of nerve repair, and limitations of current treatment strategies. Umbilical cord mesenchymal stem cells (UC-MSCs) and their secretome have shown promise as regenerative treatments due to their distinct biological characteristics. This review explores the possibility of UC-MSCs and their secretome in promoting peripheral nerve regeneration, by their action mechanisms, therapeutic applications, and current preclinical - clinical evidence. UC-MSCs have proven to be capable of support Wallerian degeneration, improving axonal growth, reducing inflammation, and improving functional recovery in both animal models and early clinical studies. Their secretome has been shown to promote neuroprotection and functional repair, avoiding the risks of receiving a direct stem cell transplant. Challenges remain in standardizing UC-MSC-based therapies, ensuring long-term safety, and enhancing delivery strategies. Further clinical trials are needed to determine the efficacy, safety, and scalability of UC-MSC therapies for widespread clinical use. UC-MSCs and their secretome provide a unique, cell-free and cell-based strategy to peripheral nerve regeneration. Future advancements in biomaterial integration, gene editing, and personalized medicine will be essential to implementing these treatments in clinical settings.

Co-Authors Adriansyah, Denny Agus Wahyudi Akbar, Hillan Arimuqti, Zarkasyi Bayudono, Sigit Brilianto, Bagus Iman Dharma, Adi Surya Effendi, Fajar Ivan Ermawan, Rieva Ernawan, Rieva Fauzi Ahmad Muda Hadinoto, Seti Aji Handojo, Handry Tri Heri Suroto Idulhaq, Mujaddid Islami, Umar Kharisma Iwan Budiwan Anwar Jiwandono, Bayu Sakti jiwandono, bayu sakti jiwandono Kumara, Hendra Cahya Mariyanto, Ismail Pradhana, Adhitya Indra Prijosedjati, Andhi Prijosedjati, R. Andhi Rhatomy, Sholahudin Rian, Rahmad Riyadli, Muhammad Romaniyanto Sabariyah, Leli Santoso, Asep Saputra, Rhyan Darma Sentana, Okkie Mharga Sibarani, Tangkas SMHS Sumarwoto, Tito Surya, Wan Adi Totok Siswanto Tulandi, M qathar RF Tulandi Widhiarso, Bagas Yurisworo, Anggita Tri

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