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PENGARUH TERAPI TAMSULOSIN DENGAN DUTASTERID TERHADAP KUALITAS HIDUP PASIEN Benign Prostate Hyperplasia di RSUD GUNUNG JATI CIREBON Pandanwangi TW, Siti; Fauzia, Rizki Rahmah
Farmasains : Jurnal Ilmiah Ilmu Kefarmasian Vol 5 No 2 (2018)
Publisher : Universitas Muhammadiyah Prof. DR. HAMKA

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (470.965 KB) | DOI: 10.22236/farmasains.v5i2.1510

Abstract

Penyakit pembesaran prostat jinak, disebut juga BPH (Benign Prostate Hyperplasia)  menjadi urutan kedua penyakit tersering, setelah penyakit batu saluran kemih yang sering dijumpai di klinik urologi Indonesia. Secara umum, 5% atau sekitar 5 juta dari jumlah pria di Indonesia sudah masuk ke dalam kelompok usia 60 tahun ke atas, dan dinyatakan bahwa sekitar 2,5 juta pria Indonesia menderita penyakit BPH. Kajian ini bertujuan untuk melihat pengaruh terapi tunggal Tamsulosin, Dutasteride pada pasien pembesaran prostat jinak atau BPH (Benign Prostate Hyperplasia) di RSUD Gunung Jati Cirebon terhadap penurunan kualitas hidupnya.  Populasi dan sampel adalah pasien BPH dengan kriteria usia ? 50 tahun tanpa penyakit penyerta Diabetes Melitus maupun Hipertensi yang berkunjung ke poli Urologi RSUD. Gunung Jati Cirebon dari Bulan Maret 2016 ? Agustus 2016. Diperoleh sampel 14 pasien dengan terapi Tamsulosin, 14 pasien dengan terapi Dutasteride. Data diperoleh dari alat bantu nilai IPSS (International Prostate Symptom Score) dan kriteria penurunan kualitas hidup. Analisa data menggunakan regresi linear untuk melihat pengaruh terapi terhadap penurunan kualitas hidup. Pemberian terapi tunggal Tamsulosin dalam penurunan rata-rata kualitas hidup pasien BPH adalah 3.109 ; Dutasteride adalah 3.276. Artinya penggunaan terapi tamsulosin lebih baik dibanding Dutasterid
Budaya Hukum Apoteker Dalam Pemberian Informasi, Edukasi dan Penyerahan Obat Keras (Daftar G) Fauzia, Rizki Rahmah
Syntax Literate Jurnal Ilmiah Indonesia
Publisher : CV. Ridwan Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (156.901 KB) | DOI: 10.36418/syntax-literate.v4i10.758

Abstract

Tujuan dari penelitian yaitu untuk memahami dan mengkaji bagaimanakah budaya hukum apoteker yang terbentuk berkaitan dengan pemberian informasi, edukasi, dan penyerahan obat keras dalam meningkatkan kualitas hidup pasien dan untuk mengkaji serta menelaah upaya-upaya yang dilakukan oleh IAI (Ikatan Apoteker Indonesia) sebagai organisasi profesi apoteker dalam menangani kasus tidak adanya pemberian informasi, edukasi, dan penyerahan obat keras oleh apoteker.Adapun metode penelitian yang digunakan yaitu dengan pendekatan non doktrinal yaitu socio-legal. Hasil penelitian menunjukkan masih adanya pembelian obat keras tanpa resep dokter dan ketidakhadiran apoteker di tempat praktik saat jam buka apotek sehingga pelayanan informasi, edukasi, dan penyerahan obat keras tidak dilakukan oleh apoteker. Hal tersebut disebabkan karena kesadaran dan kepatuhan apoteker terhadap Peraturan Pemerintah No.51 tentang Pekerjaan Kefarmasian Pasal 21 ayat (2) masih rendah sehingga terbentuklah budaya hukum yang apatis dikarenakan tidak adanya pembinaan dan pengawasan yang ketat dari Dinas Kesehatan beserta IAI sebagai organisasi profesi. Adapun upaya yang dilakukan oleh IAI terhadap apoteker yang tidak hadir di apotek sehingga tidak memberikan pelayanan informasi, edukasi, dan penyerahan obat keras dengan terus melakukan sosialisasi kepada apoteker tentang tugas dan kewajibannya, walaupun tidak adanya sanksi yang dibuat oleh organisasi profesi apabila apoteker tidak melakukan pemberian informasi, edukasi, dan penyerahan obat keras kepada pasien. Tidak adanya sanksi yang dibuat oleh organisasi profesi menandakan bahwa kesadaran dan kepatuhan pengurus organisasi IAI terhadap hukum masih kurang. Kesimpulan yang didapatkan dari penelitian ini yaitu bahwa budaya hukum apoteker dalam pemberian informasi, edukasi, dan penyerahan obat keras adalah budaya hukum yang apatis.Untuk merubah budaya hukum apoteker yang apatis tersebut maka perlu dilakukan sosialisasi ulang kepada apoteker dan pemilik fasilitas pelayanan kefarmasian. IAI sebagai organisasi profesi harus lebih mengetahui dan memahami peraturan yuridis yang berlaku serta membuat panduan tertulis (buku saku) kepada anggota profesinya. Kata Kunci : Budaya Hukum, Apoteker, Pemberian Informasi
Analisis Faktor-Faktor yang Mempengaruhi Kesadaran dan Kepatuhan Masyarakat dalam Mematuhi Protokol Kesehatan di Era Covid-19 Fauzia, Rizki Rahmah; Sundari, Retno Tresno; Arifin, Zaenal
Syntax Literate Jurnal Ilmiah Indonesia
Publisher : CV. Ridwan Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (272.937 KB) | DOI: 10.36418/syntax-literate.v6i10.4287

Abstract

Menggunakan masker, mencuci tangan dan menjaga jarak di era COVID-19 merupakan salah satu bentuk kesadaran dan kepatuhan dalam menjalankan protokol kesehatan. Penelitian ini bertujuan untuk mengetahui kesadaran dan kepatuhan masyarakat dalam mematuhi protokol kesehatan di era COVID-19 dan untuk mengetahui faktor apa saja yang mempengaruhi kesadaran dan kepatuhan masyarakat dalam mematuhi prtotkol kesehatan di era COVID-19. Penelitian ini merupakan deskriptif analitik dengan instrumen penelitian berupa wawancara dan kuesioner. Responden berjumlah 100 orang yang berusia 18-50 tahun. Adapun butir soal didalam kuesioner dilakukan uji validitas dan uji reliabilitas. Hasil penelitian berupa persentase dari faktor-faktor yang mempengaruhi kesadaran dan kepatuhan dalam mematuhi protokol kesehatan. Kesadaran dan kepatuhan masyarakat dalam mematuhi protokol kesehatan di era COVID-19 adalah sangat baik dengan persentase masyarakat yang mengetahui anjuran dari pemerintah tentang protokol kesehatan sebesar 100%, dan masyarakat yang sudah sadar dan mengerti mengenai protokol kesehatan sebesar 97%. Faktor-faktor yang mempengaruhi kesadaran dan kepatuhan masyarakat dalam mematuhi protokol kesehatan di era COVID-19 yaitu masyarakat yang sudah menggunakan masker saat keluar rumah sebesar 95%, masyarakat yang sudah patuh dengan pemerintah dengan melakukan mencuci tangan setelah keluar dari rumah sebesar 98%, masyarakat yang sudah patuh dengan anjuran pemerintah dengan selalu menjaga jarak saat berada dikerumunan sebesar 94%, masyarakat yang sudah mengetahui apabila melanggar protokol kesehatan dapat dikenakan sanksi sebesar 90%.
UJI EFEKTIVITAS SALEP EKSTRAK HERBA PEGAGAN (Centella asiatica (L.) Urban) TERHADAP LUKA BEDAH PADA TIKUS Zuniarto, Ahmad Azrul; Fauzia, Rizki Rahmah
Journal of Holistic and Health Sciences (Jurnal Ilmu Holistik dan Kesehatan) Vol. 1 No. 2 (2017): Journal of Holistic and Health Sciences (Jurnal Ilmu Holistik dan Kesehatan)
Publisher : Sekolah Tinggi Ilmu Kesehatan Holistik

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (1271.174 KB) | DOI: 10.51873/jhhs.v1i2.9

Abstract

Background: Pegagan (Centella asiatica (L.) Urban) has been studied that has good wound healing activity in surgical wound with stimulating collagen synthesis, increasing collagen secretion, stimulating fibroblast proliferation, antibacterial activity and antioxidants. Objective: To determine the effectiveness of Pegagan herb extract (Centella asiatica (L.) Urban) in healing of surgical wound in male white rat and to determine the concentration of Pegagan herb extract (Centella asiatica (L.) Urban) which is most effective against wound healing surgery in male white rat. Method: The method used experimental study. The experimental animals were divided into 5 groups, which are group X1 was the test group with Pegagan herb extract concentration of 2,5%, group X2 was the test group with Pegagan herb extract concentration of 5%, group X3 was the test group with Pegagan herb extract concentration of 10%, group K (+) was the test group with positive control, and group K (-) was the test group with negative control. Results: The results showed that the ointment of Pegagan extract with concentrations of 5% and 10% could heal the wound better than the positive control. Oinment of Pegagan extract with concentration of 2,5% had not significant difference compared with positive control (povidone iodine). Conclusion: Administration of oinment of Pegagan herb extract (Centella asiatica (L.) Urban) with concentration of 2.5%, 5%, and 10% were effective in healing of surgical wound in male white rat.
UJI EFEKTIVITAS ANTIINFLAMASI SUSPENSI EKSTRAK DAUN BAYAM DURI (Amaranthus spinosus L.) TERHADAP TIKUS PUTIH (Rattus norvegicus) YANG DIINDUKSI KARAGENAN Fauzia, Rizki Rahmah; Zuniarto, Ahmad Azrul
Journal of Holistic and Health Sciences (Jurnal Ilmu Holistik dan Kesehatan) Vol. 1 No. 2 (2017): Journal of Holistic and Health Sciences (Jurnal Ilmu Holistik dan Kesehatan)
Publisher : Sekolah Tinggi Ilmu Kesehatan Holistik

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (1063.343 KB) | DOI: 10.51873/jhhs.v1i2.11

Abstract

Background: Leaves of Thorn Spinach are one of the plants that have pharmacological activity which are to relieve pain and as anti-inflammatory. Inflammation is a normal protective response to tissue injury caused by physical trauma, destructive chemicals, or microbiological agents. In this study, the cause of inflammation was carrageenan injected in white rat. Objective: This study aimed to determine whether extract and suspension of thorn spinach leaf extract (Amaranthus spinosus L.) was useful to decrease volume of edema and to determine concentration of extract and suspension of thorn spinach leaf extract (Amaranthus spinosus L.) decrease volume of edema in male white rat (Rattus norvegicus). Methode: Study subjects were 24 males white rat (Rattus norvegicus) with weight ± 200 grams. White rats were divided into 2 large groups with 12 rats for preliminary and 12 rats for treatment. The study was conducted for 6 hours. From the data of edema volume, were calculated AUC (Area Under the Curve) that is the area under the curve between the mean volume of edema against time and percent of anti-inflammatory power. Data were analyzed using ANOVA statistic test, and T-test. Result: The result showed that extract and suspension of thorn spinach leaf extract (Amaranthus spinosus L.) had effectiveness in decreasing the volume of edema in leg of white rat (Rattus norvegicus) and extract concentration of 50% and suspension of thorn spinach leaf extract concentration of 50% had the most effectiveness in decreasing volume of edema in leg of white rat (Rattus norvegicus) with inhibition percentage as much as 15,63% and 28,08%. Conclusion: extract and suspension of thorn spinach spinach leaf (Amaranthus spinosus L.) had effectiveness in decreasing the volume of edema in leg of white rat (Rattus norvegicus) and extract concentration of 50% and suspension of thorn spinach leaf extract concentration of 50% had the most effectiveness in decreasing volume of edema in leg of white rat (Rattus norvegicus).
Effect Of Attendance Applications mobile Online (Akku Mobile) On Official Discipline At The Indramayu District Inspectorate Setiadi, Ade; Firmasnyah, Farid Indra; Kusuma, Nurul Rahmah; Fauzia, Rizki Rahmah
Jurnal Manajemen Pelayanan Publik Vol 8, No 2 (2024): Jurnal Manajemen Pelayanan Publik
Publisher : Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24198/jmpp.v8i2.51998

Abstract

Employee attendance discipline is the main indicator for knowing an employee's responsibilities. Based on observations at the Indramayu Regency Inspectorate, employee discipline in terms of attendance is still not optimal. Therefore, a policy of using electronic presence, namely an online application (Akku Mobile) has been implemented by all ASN in the Indramayu Regency Government, which is directly recorded on the BKPSDM server. The purpose of this research is to determine the effect of the Online Attendance Application (Akku Mobile) on employee discipline at the Indramayu Regency Inspectorate. The research method used is an explanatory quantitative approach to see the influence of the Online Attendance Application (Akku Mobile) on employee discipline at the Indramayu Regency Inspectorate. The data source comes from primary sources through closed questionnaires. The results of this research show that there is a positive and significant influence between the use of the Akku Mobile application on employee discipline at the Indramayu Regency Inspectorate of 0.004, while the correlation level is weak at 0.326 or only 32.6%, and the application usage variable (Akku Mobile) can only explain This relationship is 10.6% towards increasing employee discipline, while the remaining 89.4% is explained by other factors outside this research.
Yellow Pumpkin Fruit Extract (Cucurbita moschata D) in Cream Preparation as a Facial Moisturizer Fauzia, Rizki Rahmah; Nafi'ah, Rahma; Widyaningsih, Hanum
Indonesian Journal of Pharmaceutical Education Vol 5, No 1 (2025): January–April 2025
Publisher : Jurusan Farmasi Universitas Negeri Gorontalo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37311/ijpe.v5i1.26842

Abstract

Indonesia is a tropical country that has a fairly high exposure to sunlight, but excessive sun exposure can cause skin damage such as dry skin with prevalence of 41,2% to 99,1% in the elderly adult population  . Therefore, it is necessary to make products that function to moisturize the skin. Yellow pumpkin is an alternative ingredient that can be used as a skin moisturizer because it contains flavonoid compounds, tannins, saponins, alkaloids, and triterpenoids. The novelty in this study is that no one has researched yellow pumpkin fruit extract cream as a facial moisturizer, different measurement methods, substitution of ingredients in the formula from VCO to MCT and the addition of preservatives and fragrances. This study aims to determine the effectiveness of facial moisturizers, yellow pumpkin fruit extract creams, and the physical quality of preparations. In this study, the researcher used an experimental method. The extraction process uses a maceration method with a solvent of 96%, then a cream formula is made with a concentration of yellow pumpkin fruit extract of 5%, 10%, and 15%. The evaluation of facial moisturizing cream preparations includes organoleptis tests, homogeneity tests, pH tests, dispersion tests, adhesion tests, viscosity tests, and irritation tests. The tool used to measure skin moisture is Skin Analyzer CR-302 by looking at the percentage of moisture. The results of the effectiveness test of yellow pumpkin extract facial moisturizing cream (Cucurbita moschata D) for 28 days of use had a moisture percentage of 44.00% at an extract concentration of 5%, 48.67% at an extract concentration of 10%, and 55.00% at an extract concentration of 15%. The higher the concentration of the extract, the better the moisture level. The results of the effectiveness test of yellow pumpkin fruit extract cream preparations (Cucurbita moschata D) have effectiveness as a skin moisturizer with a sig value (0.008 0.050). The conclusion showed that the preparation of the moisturizing cream of yellow pumpkin fruit extract (Cucurbita moschata D) with the best concentration at a concentration of 15%. The preparation of the moisturizing cream of yellow pumpkin fruit extract (Cucurbita moschata D) meets the requirements of the evaluation test.
Hedonic Test Of Lipstick Combination Of Red Dragon Fruit Peel Extract (Hylocereus Polyrhizus) And Beetroot Tuber Extract (Beta Vulgaris L.) As Natural Colorant Fauzia, Rizki Rahmah; Karsidin, Bambang; Tristianti, Deswita
Media Farmasi Indonesia Vol. 20 No. 1 (2025): Media Farmasi Indonesia
Publisher : SEKOLAH TINGGI ILMU FARMASI YAYASAN PHARMASI SEMARANG

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53359/mfi.v20i1.303

Abstract

Not all waste from natural materials produced can be utilized properly by humans to produce higher economic value. The waste in question is red dragon fruit skin which contains anthocyanin pigments and betasianin pigments. Pigments can be used as colorants in lipstick but the intensity of the resulting color is less attractive. This study aims to determine the lipstick combination of Red Dragon fruit peel extract (Hylocereus polyrhizus) and Beet tuber extract (Beta vulgaris L.) most preferred by panelists as a natural colorant. The method used in this study was experimental. Preparation of Red Dragon fruit peel extract and Beetroot tuber extract using maceration method with 70% ethanol solvent. Then the extract was made into 3 lipstick preparation formulas at a concentration of 30% with a ratio of 1: 2 (X1), 1,5 : 1.5 (X2) and 2: 1 (X3). Hedonic tests include texture, color, aroma and appearance of lipstick preparations using a Likert scale. The combination lipstick produces color and percentage of liking, namely purple and preferred by 43.75% (X1), pink with 51.25% hedonic percentage (X2), and the most preferred by 58.75% (X3) with a dark red color, while the negative control has a yellow color with the smallest liking value of 28.75%.