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Fauzia, Rizki Rahmah
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Humanities Biochemistry, Genetics & Molecular Biology Chemistry Decision Sciences, Operations Research & Management Economics, Econometrics & Finance Education Environmental Science Health Professions Immunology & microbiology Law, Crime, Criminology & Criminal Justice Materials Science & Nanotechnology Medicine & Pharmacology Nursing Public Health Social Sciences Transportation Other

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EFEKTIVITAS ANTI-KANKER PAYUDARA SUSPENSI EKSTRAK BIJI PEPAYA (Carica papaya L.) PADA TIKUS PUTIH BETINA YANG DIINDUKSI DENGAN LARUTAN BENZENA Fauzia, Rizki Rahmah; Yunita, Intan; Nafiah, Rahma
Praeparandi : Jurnal Farmasi dan Sains Vol 6 No 2 (2023): Praeparandi : Jurnal Farmasi dan Sains
Publisher : Praeparandi : Jurnal Farmasi dan Sains

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (450.83 KB) | DOI: 10.58365/ojs.v6i2.201

Abstract

Biji Pepaya (Carica papaya L) merupakan salah satu tanaman yang dapat digunakan sebagai melawan kanker, mengatasi virus, mengatasi peradangan, kontrasepsi alami, dan baik untuk hati. Kandungan flavanoid dan alkaloid mempunyai efektifitas sebagai alternatif antikanker. Tujuan dari penelitian ini adalah untuk mengetahui efektivitas suspensi ekstrak biji pepaya sebagai anti-kanker terhadap payudara tikus betina yang diinduksi larutan benzene dengan dilihat tiga parameter yaitu jumlah sel neutrofil, berat badan dan diameter payudara tikus betina dan untuk mengetahui pada dosis berapakah suspensi ekstrak biji papaya (Carica papaya L.) sebagai anti-kanker terhadap payudara tikus betina yang diinduksi larutan benzene. Penelitian ini bersifat eksperimental, ekstraksi dilakukan dengan metode maserasi menggunakan etanol 70%. Dosis yang digunakan adalah 1050 mg/KgBB, 1400 mg/KgBB, dan 1750 mg/KgBB. Penelitian dilakukan dengan menghitung berat badan tikus pre dan post, menghitung diameter payudara tikus pre dan post serta menghitung nilai neutrofil tikus pre dan post tikus putih betina. Dalam metode ini terdiri dari 6 kelompok, masing-masing kelompok terdiri dari 3 ekor tikus. Kelompok I,II dan III dengan pemberian suspensi ekstrak biji pepaya, kelompok IV dengan pemberian suspensi suspensi tablet xeloda, kelompok V dengan pemberian basis suspensi dan kelompok VI tidak diberi perlakuan. Untuk mengetahui perbedaan pada setiap perlakuan dilakukan analisis Kruskal-Wallis dan one way anava dan untuk mengetahui perbedaan antara dua kelompok perlakuan dilakukan uji Mann-Whiteney dan anova. Hasil uji statistik menunjukkan bahwa suspensi ekstrak biji pepaya memiliki efektifitas sebagai anti-kanker payudara pada tikus putih betina, dan suspensi ekstrak biji pepaya pada dosis 1050 mg/KgBB memiliki efektifitas anti-kanker payudara yang sebanding dengan kontrol positif (Xeloda).
Effect Of Attendance Applications mobile Online (Akku Mobile) On Official Discipline At The Indramayu District Inspectorate Setiadi, Ade; Firmasnyah, Farid Indra; Kusuma, Nurul Rahmah; Fauzia, Rizki Rahmah
Jurnal Manajemen Pelayanan Publik Vol 8, No 2 (2024): Jurnal Manajemen Pelayanan Publik
Publisher : Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24198/jmpp.v8i2.51998

Abstract

Employee attendance discipline is the main indicator for knowing an employee's responsibilities. Based on observations at the Indramayu Regency Inspectorate, employee discipline in terms of attendance is still not optimal. Therefore, a policy of using electronic presence, namely an online application (Akku Mobile) has been implemented by all ASN in the Indramayu Regency Government, which is directly recorded on the BKPSDM server. The purpose of this research is to determine the effect of the Online Attendance Application (Akku Mobile) on employee discipline at the Indramayu Regency Inspectorate. The research method used is an explanatory quantitative approach to see the influence of the Online Attendance Application (Akku Mobile) on employee discipline at the Indramayu Regency Inspectorate. The data source comes from primary sources through closed questionnaires. The results of this research show that there is a positive and significant influence between the use of the Akku Mobile application on employee discipline at the Indramayu Regency Inspectorate of 0.004, while the correlation level is weak at 0.326 or only 32.6%, and the application usage variable (Akku Mobile) can only explain This relationship is 10.6% towards increasing employee discipline, while the remaining 89.4% is explained by other factors outside this research.
Yellow Pumpkin Fruit Extract (Cucurbita moschata D) in Cream Preparation as a Facial Moisturizer Fauzia, Rizki Rahmah; Nafi'ah, Rahma; Widyaningsih, Hanum
Indonesian Journal of Pharmaceutical Education Vol 5, No 1 (2025): January–April 2025
Publisher : Jurusan Farmasi Universitas Negeri Gorontalo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37311/ijpe.v5i1.26842

Abstract

Indonesia is a tropical country that has a fairly high exposure to sunlight, but excessive sun exposure can cause skin damage such as dry skin with prevalence of 41,2% to 99,1% in the elderly adult population  . Therefore, it is necessary to make products that function to moisturize the skin. Yellow pumpkin is an alternative ingredient that can be used as a skin moisturizer because it contains flavonoid compounds, tannins, saponins, alkaloids, and triterpenoids. The novelty in this study is that no one has researched yellow pumpkin fruit extract cream as a facial moisturizer, different measurement methods, substitution of ingredients in the formula from VCO to MCT and the addition of preservatives and fragrances. This study aims to determine the effectiveness of facial moisturizers, yellow pumpkin fruit extract creams, and the physical quality of preparations. In this study, the researcher used an experimental method. The extraction process uses a maceration method with a solvent of 96%, then a cream formula is made with a concentration of yellow pumpkin fruit extract of 5%, 10%, and 15%. The evaluation of facial moisturizing cream preparations includes organoleptis tests, homogeneity tests, pH tests, dispersion tests, adhesion tests, viscosity tests, and irritation tests. The tool used to measure skin moisture is Skin Analyzer CR-302 by looking at the percentage of moisture. The results of the effectiveness test of yellow pumpkin extract facial moisturizing cream (Cucurbita moschata D) for 28 days of use had a moisture percentage of 44.00% at an extract concentration of 5%, 48.67% at an extract concentration of 10%, and 55.00% at an extract concentration of 15%. The higher the concentration of the extract, the better the moisture level. The results of the effectiveness test of yellow pumpkin fruit extract cream preparations (Cucurbita moschata D) have effectiveness as a skin moisturizer with a sig value (0.008 0.050). The conclusion showed that the preparation of the moisturizing cream of yellow pumpkin fruit extract (Cucurbita moschata D) with the best concentration at a concentration of 15%. The preparation of the moisturizing cream of yellow pumpkin fruit extract (Cucurbita moschata D) meets the requirements of the evaluation test.
Hedonic Test Of Lipstick Combination Of Red Dragon Fruit Peel Extract (Hylocereus Polyrhizus) And Beetroot Tuber Extract (Beta Vulgaris L.) As Natural Colorant Fauzia, Rizki Rahmah; Karsidin, Bambang; Tristianti, Deswita
Media Farmasi Indonesia Vol. 20 No. 1 (2025): Media Farmasi Indonesia
Publisher : SEKOLAH TINGGI ILMU FARMASI YAYASAN PHARMASI SEMARANG

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53359/mfi.v20i1.303

Abstract

Not all waste from natural materials produced can be utilized properly by humans to produce higher economic value. The waste in question is red dragon fruit skin which contains anthocyanin pigments and betasianin pigments. Pigments can be used as colorants in lipstick but the intensity of the resulting color is less attractive. This study aims to determine the lipstick combination of Red Dragon fruit peel extract (Hylocereus polyrhizus) and Beet tuber extract (Beta vulgaris L.) most preferred by panelists as a natural colorant. The method used in this study was experimental. Preparation of Red Dragon fruit peel extract and Beetroot tuber extract using maceration method with 70% ethanol solvent. Then the extract was made into 3 lipstick preparation formulas at a concentration of 30% with a ratio of 1: 2 (X1), 1,5 : 1.5 (X2) and 2: 1 (X3). Hedonic tests include texture, color, aroma and appearance of lipstick preparations using a Likert scale. The combination lipstick produces color and percentage of liking, namely purple and preferred by 43.75% (X1), pink with 51.25% hedonic percentage (X2), and the most preferred by 58.75% (X3) with a dark red color, while the negative control has a yellow color with the smallest liking value of 28.75%.
Co-Authors , stf1 Auliya, Muhammad Febri AYATULOH, AJI FAHMI Dewi, Herlina Putri Fauziah, Alvina Iza Firmasnyah, Farid Indra Karsidin, Bambang Kusuma, Nurul Rahmah Nafi'ah, Rahma Nafiah, Rahma Santoso, Aman Budi Setiadi, Ade Siti Pandanwangi TW Sundari, Retno Tresno Tristianti, Deswita Wati, Tiara Diyana Widyaningsih, Hanum Yunita, Intan Zaenal Arifin Zuniarto, Ahmad Azrul