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All Journal Biogenesis: Jurnal Ilmiah Biologi Jurnal Pengabdian Kepada Masyarakat Sakai Sambayan Jurnal Kesehatan Medical Technology and Public Health Journal Jurnal Analis Farmasi Jurnal Inovasi Farmasi Indonesia JAF (Jurnal Analis Farmasi)
Yustin Nur Khoiriyah
Politeknik Kesehatan Kementerian Kesehatan Tanjungkarang
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Computer Science & IT Decision Sciences, Operations Research & Management Environmental Science Health Professions Immunology & microbiology Medicine & Pharmacology Nursing Public Health Other

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Karakter Genetik Populasi Bedeng 61B Desa Wonokarto Kabupaten Lampung Timur Pasca Program Kolonisasi Pemerintah Belanda Nur Khoiriyah, Yustin
Biogenesis Vol 2, No 2 (2014)
Publisher : Jurusan Biologi UIN Alauddin Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Gene and genotype frequencies are important in a population characterizing. Based on the frequency of these gene and genotype, distinctiveness of population can be determined (Arisuryanti et al., 2007). Gene frequencies of population can be changed if there are evolutionary forces (the factors that play a role in changing the allele and genotype frequencies), such as, mutation, migration, non-random mating, genetic drift and natural selection (Arisuryanti & Daryono, 2007). Migration and genetic drift were thought to be a factor that changed alleles and genotype frequencies in the population of Lampung. Witrianto (2010) showed migration programs that were triggered by the Dutch government, it was called colonization. Therefore, in the population of Lampung, indication of changes in allele and genotype frequencies were need to be evaluated. The results showed that frequency of alleles IA, IB and IO in the population were 0.17; 0.21 and 0.62, respectively. Frequency of genotype IAIA, IAIO, IBIB, IBIO, IAIB and IOIO were 0.290; 0.2108; 0.0441; 0.2604; 0.0650 and 0.3800, respectively. Chi Square test showed that the value of X2 were 0,07 (X2 < α critical value at 5% for dF = 3). It can be concluded that alleles and genotype distribution of ABO blood system in the population were in accordance with Hardy Weinberg equilibrium law, so that the equilibrium legal status were applied in this population. Genetic drift and gene flow were not affected alleles and genotype changes. The process of microevolution were not occur in the population of people from the 61 B plot of Wonokarto village.Keywords: character of genetic population, post-colonization of Dutch government, the 61 B plot ofWonokarto village
Karakter Genetik Populasi Bedeng 61B Desa Wonokarto Kabupaten Lampung Timur Pasca Program Kolonisasi Pemerintah Belanda Yustin Nur Khoiriyah
Biogenesis: Jurnal Ilmiah Biologi Vol 2 No 2 (2014)
Publisher : Department of Biology, Faculty of Sci and Tech, Universitas Islam Negeri Alauddin Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24252/bio.v2i2.480

Abstract

Gene and genotype frequencies are important in a population characterizing. Based on the frequency of these gene and genotype, distinctiveness of population can be determined (Arisuryanti et al., 2007). Gene frequencies of population can be changed if there are evolutionary forces (the factors that play a role in changing the allele and genotype frequencies), such as, mutation, migration, non-random mating, genetic drift and natural selection (Arisuryanti & Daryono, 2007). Migration and genetic drift were thought to be a factor that changed alleles and genotype frequencies in the population of Lampung. Witrianto (2010) showed migration programs that were triggered by the Dutch government, it was called colonization. Therefore, in the population of Lampung, indication of changes in allele and genotype frequencies were need to be evaluated. The results showed that frequency of alleles IA, IB and IO in the population were 0.17; 0.21 and 0.62, respectively. Frequency of genotype IAIA, IAIO, IBIB, IBIO, IAIB and IOIO were 0.290; 0.2108; 0.0441; 0.2604; 0.0650 and 0.3800, respectively. Chi Square test showed that the value of X2 were 0,07 (X2 < α critical value at 5% for dF = 3). It can be concluded that alleles and genotype distribution of ABO blood system in the population were in accordance with Hardy Weinberg equilibrium law, so that the equilibrium legal status were applied in this population. Genetic drift and gene flow were not affected alleles and genotype changes. The process of microevolution were not occur in the population of people from the 61 B plot of Wonokarto village.Keywords: character of genetic population, post-colonization of Dutch government, the 61 B plot ofWonokarto village
Kajian Ragam dan Periode Penyimpanan Kombinasi Air Rebusan Daun Sirih dan Kayu Siwak Terhadap Pertumbuhan Streptococcus mutans Yustin Nur Khoiriyah; Sri Murwaningsih
Biogenesis: Jurnal Ilmiah Biologi Vol 5 No 2 (2017)
Publisher : Department of Biology, Faculty of Sci and Tech, Universitas Islam Negeri Alauddin Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24252/bio.v5i2.3865

Abstract

The community for maintaining healthy teeth and mouth has used betel and siwak wood plants. However, the benefits of a combination of both plants have not been widely known. The main output of this research was to know the utilization of a combination of betel leaf water and siwak wood as a mouthwash candidate. Combination of boiled water of both plants is a processed product, which has a shelf life. As a mouthwash product that is stored for a long time allegedly decreased the level of usefulness. One parameter of usability level to be observed in this study was the inhibition of Streptococcus mutans, the bacteria that cause dental caries. This study was laboratory experimental research, and use post test only with control group design with Cross-Sectional approach. Data analyzed by T-test and ANOVA followed by LSD test. Inhibition zone of boiled water stored at room temperature was smaller than cold temperature. However, T-test results showed that the diameter of inhibition zone of boiled water stored at room temperature and the cold temperature was not significantly different (p-value = 0,586> 0,05). Significantly decreased drag zone diameters occurred in a combination of boiled water stored for 16 and 18 days. Then the storage variety did not have a real effect, while the storage period significantly affects the inhibition power of boiled water in the growth of Streptococcus mutans.
MUTU HEDONIK DAN TINGKAT KESUKAAN KOMBINASI AIR REBUSAN DAUN SIRIH DAN KAYU SIWAK SEBAGAI KANDIDAT OBAT KUMUR Yustin Nur Khoiriyah; Sri Wahyuni
Jurnal Analis Farmasi Vol 2, No 4 (2017): Volume 2 Nomor 4
Publisher : Program Studi Analisis Farmasi dan Makanan Universitas Malahayati

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (422.462 KB) | DOI: 10.33024/jaf.v2i4.2141

Abstract

ABSTRAKKombinasi air rebusan daun sirih dan kayu siwak memiliki konsentrasi daya hambat terkecil yaitu 30% terhadap bakteri penyebab karies gigi yaitu Streptococcus mutans [8]. Kemampuan tersebut menjadi dasar pengembangan formula obat kumur alami, dimana dalam pemanfaatannya perlu dilakukan uji kelayakan terhadap pengguna. Maka penelitian ini dilakukan penilaian mutu hedonik dan tingkat kesukaan dari kombinasi air rebusan daun sirih dan kayu siwak sebagai kandidat obat kumur. Jenis penelitian eksperimen dengan rancangan post test only. Jumlah sampel uji mutu hedonik dan tingkat kesukaan, berturut-turut yaitu 25 dan 100 orang dengan usia 16-17 tahun. Hasil penilaian mutu hedonik yaitu nilai mutu baik dengan rentang nilai rerata tanggapan yaitu 3,6 – 4,18 (skala 0-6). Tingkat kesukaan masih rendah, dimana nilai rerata tanggapan berada pada rentang 2,3 – 3,55 (skala 0-6). Keenam parameter yang telah dinilai, tiga diantaranya diberi tanggapan pada rentang agak baik dan baik serta agak disukai yaitu aroma, rasa dan sensasi di mulut. Parameter kejernihan dan warna, tekstur dan kekentalan serta penampilan umum diberi tanggapan baik dan disukai. Peningkatan mutu aroma, rasa dan sensasi di mulut perlu dilakukan dengan memberikan bahan tambahan seperti aroma dan perasa buah-buahan serta daun mint untuk sensasi segar di mulut.Kata kunci : Kombinasi, rebusan, sirih, kayu siwak, mutu hedonik, tingkat kesukaan, obat kumur
PENINGKATAN KUALITAS HIDUP SEHAT DAN PENCEGAHAN PENYAKIT BERBASIS LINGKUNGAN MELALUI PELATIHAN KADER DAN REMAJA SERTA PERBAIKAN SARANA SANITASI Mei Ahyanti; Sri Ujiani; yustin nur khoiriyah; ririn sri handayani; I Gusti Ayu Mirah Widhisastri; Tori Rihiantoro
Jurnal Pengabdian Kepada Masyarakat Sakai Sambayan Vol 4 No 1 (2020)
Publisher : Lembaga Penelitian dan Pengabdian Universitas Lampung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23960/jss.v4i1.180

Abstract

Permasalahan kesehatan di masyarakat semakin kompleks. Permasalahan penyakit menular belum terselesaikan, sudah makin marak penyakit tidak menular. Permekes RI No. 36 tahun 2016 pasal 1 menyebutkan bahwa Penyelenggaraan Program Indonesia Sehat dengan Pendekatan Keluarga. Desa II Sukasari Desa Sukadadi Kecamatan Gedong Tataan Kabupaten Pesawaran Provinsi Lampung merupakan salah satu daerah dengan permasalahan komplek. Dengan permasalahan kesehatan yang ada dimasyarakat dibutuhkan kesadaran dan keterampilan masyarakat dalam melakukan upaya-upaya pencegahan dan pengendalian terhadap kejadian penyakit agar tidak semakin berat. Dalam mencapai tujuan tersebut, memerlukan peranan dari berbagai tenaga kesehatan secara terintegrasi dari berbagai disiplin ilmu berbeda yang memiliki kompetensi dan bekerja secara team work. Pelaksanaan pengabdian masyarakat Masyarakat di Desa Sukadadi Kecamatan Gedong Tataan Kabupaten Pesawaran diawali dengan penyamaan persepsi, pelatihan kader dan pendampingan dalam pembuatan sarana sanitasi. Terjadi perbedaan hasil pengukuran pengetahuan dan sikap antara sebelum dan setelah kegiatan pelatihan menunjukkan keberhasilan kegiatan pelatihan dan terbangun satu buah jamban keluarga sederhana sehat sebagai percontohan.
MUTU HEDONIK DAN TINGKAT KESUKAAN KOMBINASI AIR REBUSAN DAUN SIRIH DAN KAYU SIWAK SEBAGAI KANDIDAT OBAT KUMUR Yustin Nur Khoiriyah; Sri Wahyuni
Jurnal Analis Farmasi Vol 2, No 4 (2017): Volume 2 Nomor 4
Publisher : Program Studi Analisis Farmasi dan Makanan Universitas Malahayati

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (422.462 KB) | DOI: 10.33024/jaf.v2i4.2141

Abstract

ABSTRAKKombinasi air rebusan daun sirih dan kayu siwak memiliki konsentrasi daya hambat terkecil yaitu 30% terhadap bakteri penyebab karies gigi yaitu Streptococcus mutans [8]. Kemampuan tersebut menjadi dasar pengembangan formula obat kumur alami, dimana dalam pemanfaatannya perlu dilakukan uji kelayakan terhadap pengguna. Maka penelitian ini dilakukan penilaian mutu hedonik dan tingkat kesukaan dari kombinasi air rebusan daun sirih dan kayu siwak sebagai kandidat obat kumur. Jenis penelitian eksperimen dengan rancangan post test only. Jumlah sampel uji mutu hedonik dan tingkat kesukaan, berturut-turut yaitu 25 dan 100 orang dengan usia 16-17 tahun. Hasil penilaian mutu hedonik yaitu nilai mutu baik dengan rentang nilai rerata tanggapan yaitu 3,6 – 4,18 (skala 0-6). Tingkat kesukaan masih rendah, dimana nilai rerata tanggapan berada pada rentang 2,3 – 3,55 (skala 0-6). Keenam parameter yang telah dinilai, tiga diantaranya diberi tanggapan pada rentang agak baik dan baik serta agak disukai yaitu aroma, rasa dan sensasi di mulut. Parameter kejernihan dan warna, tekstur dan kekentalan serta penampilan umum diberi tanggapan baik dan disukai. Peningkatan mutu aroma, rasa dan sensasi di mulut perlu dilakukan dengan memberikan bahan tambahan seperti aroma dan perasa buah-buahan serta daun mint untuk sensasi segar di mulut.Kata kunci : Kombinasi, rebusan, sirih, kayu siwak, mutu hedonik, tingkat kesukaan, obat kumur
The Profil Fitokimia Ekstrak Daun Salam (Eugenia polyantha Wight): Metode Infundasi, Dekoktasi, Maserasi dan Soxhletasi: Phytochemical Profile of Bay Leaf Extract (Eugenia polyantha Wight): Infundation, Decoccation, Maceration and Soxhletation Methods Yustin Nur Khoiriyah
Jurnal Inovasi Farmasi Indonesia (JAFI) Vol. 4 No. 2 (2023): Jurnal Inovasi Farmasi Indonesia (JAFI)
Publisher : Universitas Kadiri

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30737/jafi.v4i2.4612

Abstract

 Fitokimia memberikan informasi tentang cara mengisolasi hasil metabolisme sekunder sertamengidentifikasi golongan senyawa. Jenis dan jumlah senyawa yang berbeda dapat diperoleh dengan metode isolasi yang sesuai, kelompok senyawa yang diekstraksi dapat diisolasi dengan metode khusus dan metode isolasi yang berbeda. Hal perlu dikaji pada berbagai tumbuhan yang bermanfaat obat, sehingga berdasarkan hal tersebut dapat dipilih metode isolasi yang sesuai dengan tujuan dan kegunaannya. Oleh karena itu, penelitian ini dilakukan untuk mengetahui profil fitokimia daun salam berdasarkan distribusi Rf pada uji kromatografi lapis tipis. Bahan uji adalah daun salam, metode ekstraksi antara lain infundasi, dekoktasi, maserasi dan soxhletasi. Perbedaan kandungan golongan senyawa dari hasil ekstraksi diketahui dengan visualisasi noda/ bercak lempeng Kromatografi Lapis Tipis (KLT) pada UV 254, UV 366 dan pereaksi semprot AlCl3, Formaldehida, FeCl3, KOH, Lieberman-Burchard dan Dragendrooff. Hasil penelitian menunjukkan jumlah bercak yang terlihat dari maserat 3 (tiga) bercak dengan Rf 0,13; 0,94; 0,97, ekstrak  soxhlet 4 (empat) bercak dengan Rf 0,15; 0,86; 0,92; 0,94, infusa 3 (tiga) bercak dengan Rf 0,06; 0,14; 0,94, dan dekokta 3 (tiga) bercak dengan Rf 0,06; 0,13; 0,97. Senyawa yang terkandung dalam infusa, dekokta, maserasi dan soxhletasi daun salam terdiri dari flavonoid, terpenoid, triterpenoid, fenolik, kumarin dan antrakuinon. Senyawa yang selalu terlihat pada infusa, dekokta, maserasi dan soxhletasi daun salam adalah terpenoid/triterpenoid. Metode maserasi dan soxhletasi dari daun salam, menghasilkan golongan senyawa flavonoid, kumara, dan antrakuinon. Profil fitokimia daun salam berbeda tergantung pada metode ekstraksi infusa, dekokta, maserasi, dan soxhletasi.
Impact of Storage on Alteration in Biochemical and Hematological Characteristics in Locally Donated Blood from Lampung Province: Assessing Potential Risks for Recipients Yuniza, Filia; Nur Khoiriyah, Yustin; Danan Jaya, Bayu Putra
TEKNOLOGI MEDIS DAN JURNAL KESEHATAN UMUM Vol 8 No 1 (2024): Medical Technology and Public Health Journal March 2024
Publisher : Universitas Nahdlatul Ulama Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33086/mtphj.v8i1.5219

Abstract

The utilization of stored blood for transfusion purposes is a common practice in Blood Transfusion Units worldwide. However, the storage period can induce various cellular alterations, potentially comprising the quality and efficacy of blood transfusions. This study aims to investigate changes in biochemical and hematological parameters in blood donors during the storage period. This study was a prospective study involving the observation of 10 blood bags collected from local community donors in Lampung Province. The blood samples were stored in CPDA-1 anticoagulant bags at a controlled temperature of 2-6 ° C for 35 days. At regular intervals of 7 days, comprehensive assessments were performed, encompassing complete blood parameters, electrolyte concentration (Na+, K+, Cl-), and blood pH levels. After 35 days of storage, statistically significant alterations were observed. Notably, there was a significant increase in hematocrit levels (p=0.000), mean corpuscular volume (MCV) (p=0.019), lymphocyte counts (p=0.000), and potassium concentrations (p=0.000). Conversely, mean corpuscular hemoglobin concentration (MCHC) (p=0.025), leukocyte counts (p=0.000), neutrophil counts (p=0.000), platelet counts (p=0.000), sodium levels (p=0.000), chloride levels (p=0.000), and pH values (p=0.000) were significantly declines. In conclusion, blood storage leads to notable alterations in biochemical and blood cell characteristics. Therefore, it is advisable to prioritize using fresh whole blood or blood stored for no more than seven days in transfusion practices to minimize the risk of post-transfusion reactions, especially in vulnerable recipients.  Keywords: Blood transfusion, biochemical changes, cellular changes, storage.
Aplikasi Dekokta Daun Salam dalam Penghambatan Candidiasis Eritematosa pada Pengguna Gigi Tiruan Lepasan Akrilik Khoiriyah, Yustin Nur; Wahyuni, Sri
Jurnal Kesehatan Vol 13 No 3 (2022): Jurnal Kesehatan
Publisher : Poltekkes Kemenkes Tanjung Karang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26630/jk.v13i3.3536

Abstract

The use of acrylic removable dentures can cause problems if they are not paid attention to cleanliness and care. This can result in a buildup of food waste which predisposes to plaque formation, thereby increasing the prevalence of candida albicans microorganisms and causing candidiasis. The most commonly found candidiasis is erythematous candidiasis. Bay leaf because it contains essential oils, flavonoids, and tannins that can act as anti-bacterial in the mouth and are safe for health. The bay leaf ethanol extracts of 40% v/v (7mm), 80% v/v (9mm), and 100% v/v (11mm) were effective in inhibiting the growth of Candida ATCC 10231 in Sabouraud Dextrose Agar (SDA). Based on the antimicrobial activity of the bay leaf, the researchers wanted to conduct a study on the effectiveness of the bay leaf in inhibiting the occurrence of erythematous candidiasis in acrylic denture users. This type of research is experimental research and uses a pre-and post-test design with a control group. Data analysis using pair T-test. The results of the initial erythematous candidiasis examination showed that the frequency distribution of the type of erythematous candidiasis in respondents was 100% type I, simple inflammation was localized and the area of erythematous candidiasis was 100% type 1, pinpoints hyperemia. The application of bay leaf decoction in respondents caused 75% of respondents to experience a change in the type and extent of the lesion from type I to normal (no lesions). The paired samples t-test showed a significance of 0.008
Efektivitas Ecoenzyme dari Kulit Buah sebagai Disinfektan Lantai yang Ramah Lingkungan Sarlinda, Febrina; Khoiriyah, Yustin Nur
Jurnal Kesehatan Vol 14 No 3 (2023): Jurnal Kesehatan
Publisher : Poltekkes Kemenkes Tanjung Karang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26630/jk.v14i3.4254

Abstract

Lantai merupakan salah satu area yang rentan menjadi tempat berkumpulnya kuman dan bakteri. Bakteri patogen yang sering ditemui di lantai antara lain E.coli, Pseudomonas aeruginosa, Enterobacter cloacae, Salmonella sp, Staphylococcus aureus yang semuanya dapat menyebabkan terjadinya berbagai macam penyakit. Penelitian ini bertujuan untuk mengetahui efektifitas ecoenzyme dari sampah kulit buah sebagai pembersih lantai desinfektan. Penelitian eksperimen ini dirancang dengan variabel jenis ecoenzyme (dari kulit buah asam dan kulit buah manis) serta variabel konsentrasi ecoenzyme (5%, 10%, 15%, 20, 40%, 60%, 80%) dengan pembanding desinfektan pembersih lantai komersil yang mengandung bahan aktif pine oil. Hasil analisis menunjukkan bahwa ecoenzyme efektif menurunkan jumlah angka kuman pada lantai. Hasil uji two way anova menunjukkan adanya perbedaan signifikan antara kedua jenis ecoenzyme dan konsentrasi ecoenzyme dalam menurunkan angka kuman lantai. Ecoenzyme dari kulit buah manis lebih efektif menurunkan jumlah angka kuman lantai daripada ecoenzyme kulih buah asam. Semakin tinggi konsentrasi econzyme yang digunakan sebagai cairan disinfektan, semakin tinggi persentase pengurangan jumlah angka kuman lantai. Pada konsentrasi ecoenzyme 80%, ecoenzyme kulit buah manis mampu menurunkan angka kuman hingga 86,16% dan ecoenzyme kulit buah asam 78,29%. Dibandingkan dengan disinfektan dari pembersih lantai komersial konsentrasi 0,5%, persentase penurunan angka kuman lantai setara dengan ecoenzyme kulit buah asam pada konsentrasi 71,8% dan ecoenzyme kulit buah manis pada konsentrasi 32%.
Co-Authors Danan Jaya, Bayu Putra Filia Yuniza Mei Ahyanti Ririn Sri Handayani Sarlinda, Febrina Sastri, I Gusti Ayu Mirah Widhi Sri Murwaningsih SRI UJIANI Sri Wahyuni Sri Wahyuni Tori Rihiantoro