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All Journal Majalah Obat Tradisional Pharmascience Kesmas Indonesia: Jurnal Ilmiah Kesehatan Masyarakat Acta Pharmaciae Indonesia : Acta Pharm Indo Syntax Literate: Jurnal Ilmiah Indonesia PHARMACY: Jurnal Farmasi Indonesia (Pharmaceutical Journal of Indonesia) JURNAL FARMASI GALENIKA Jurnal Ilmiah Medicamento Jurnal Buana Farma Jurnal Pengabdian dan Pengembangan Masyarakat Indonesia Journal of Global Pharma Technology Medical Sains : Jurnal Ilmiah Kefarmasian Jurnal Kefarmasian Indonesia Journal of Pharmacopoeia
Genatrika, Erza
Fakultas Farmasi, Universitas Muhammadiyah Purwokerto
Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Chemistry Economics, Econometrics & Finance Education Environmental Science Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Materials Science & Nanotechnology Medicine & Pharmacology Nursing Public Health Social Sciences Other

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Uji Sensitisasi Dermal Masker Gel Kombinasi Ekstrak Ampas Daun Teh dan Air Cucian Beras Annisa, Andi Nurul; Utaminingrum, Wahyu; Genatrika, Erza
Jurnal Kefarmasian Indonesia VOLUME 9, NOMOR 1, FEBRUARI 2019
Publisher : Pusat Penelitian dan Pengembangan Biomedis dan Teknologi Dasar Kesehatan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22435/jki.v9i1.491

Abstract

The combination of tea leaf dregs extract and rice washing water as a peel-off gel mask was found to be stable up to 28 days of storage and had an IC50 value 20.4 ppm. This potential can provide an optimal effects as cosmetic ingredients.However, to meet the regulatory requirements of Badan Pengawas Obat Makanan (BPOM) RI and ISO 10993, a dermal sensitization test also need to be done. The aim of this study was to determine the dermal sensitization reaction from peel-off gel mask containing a combination of tea leaf dregsextract (Camellia sinensis L.) and rice washing water (Oryza sativa L.) in test animal. Thisstudy was designed based on experimental laboratory methods and sample selection by simple random sampling. The intervention was given based on posttest-only control group design. The test results for dermal sensitization were determined using the Guinea Pig Maximization Test (GPMT) method. The results showed erythema and edema reactions according to the Magnusson and Kligman scale after administration of peel-off gel masks as samples in the topical tests in test animals, appeared on the 11th day and in the challenge test appeared on the 24th day. This was due to incubation period for one week where the hypersensitivity state can develop, so that this reaction is also called the delayed hypersensitivity reaction
DEVELOPMENT OF SUNSCREEN PRODUCTS CONTAINING Stichopus hermanii Semper, 1868 Widyowati, Ulfi; Genatrika, Erza; Djalil, Asmiyenti Djaliasrin
Medical Sains : Jurnal Ilmiah Kefarmasian Vol 9 No 3 (2024)
Publisher : Sekolah Tinggi Farmasi Muhammadiyah Cirebon

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37874/ms.v9i3.1138

Abstract

Prolonged radiation from UV sunlight has been known to be responsible for skin damage. Sunscreen has been used to limit sun exposure. Sunscreen with natural ingredients has the potential to be developed along with the issue of side effects of synthetic ingredients. This study aimed to develop a zooceuticals sunscreen cream containing a Stichopus hermanii Semper, 1868 extracts. The sunscreen creams were formulated with various ingredients of extract include 0.05 (F1), 0.1 (F2), and 0.2 (F3) %, respectively. The in vitro sun protection factor, organoleptic properties, homogeneity, pH, viscosity, spreadability, and adhesion of the creams were evaluated. F3 met the requirements of physical properties. The extract show sun-protective efficacy with SPF value of 2.11 (F1), 3.09 (F2), and 3.46 (F3). Sunscreen containing 0.2% of Stichopus herrmanni extract is the most preferred formulation with minimal protection category.  Keywords: Sea Cucumber, Stichopus hermanii Semper, 1868, Sunscreen.
FORMULASI OBAT KUMUR EKSTRAK KULIT PISANG KEPOK KUNING (Musa paradisiaca L.) SEBAGAI ANTIBAKTERI Julyanti, Ai Rian; Genatrika, Erza; Annissya, Widia Primi; Setyaningrum, Nenden; Ferliati, Rosi Eka; Pratama, Okta Nurandi
Jurnal Buana Farma Vol. 4 No. 4 (2024): Jurnal Buana Farma : Jurnal Ilmiah Farmasi
Publisher : Fakultas Farmasi Universitas Buana Perjuangan Karawang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36805/jbf.v4i4.1151

Abstract

Yellow kepok banana peel (Musa paradisiaca L.) contains alkaloid, flavonoid, and tannin compounds that are known to have antibacterial activity. This study was conducted to determine the antibacterial activity of mouthwash from yellow kepok banana peel in inhibiting the growth of Streptococcus mutans. The yellow kepok banana peel used the maceration method with 96% ethanol solvent, then mouthwash preparation formulations with the extract concentrations of 2%, 4%, and 8%. The antibacterial activity of the mouthwash preparation was tested against Streptococcus mutans using the disc diffusion method. The results showed that the mouthwash formula of yellow kepok banana peel extract had inhibitory power on Streptococcus mutans bacteria with an inhibition zone of 9.52 mm in formula I, formula II 10.67 mm, and formula III 12.36 mm. Formulas I and II are classified as moderate antibacterial activity categories, while formula III is classified as having strong antibacterial activity. The results showed a p <0.05, meaning each test group has a significant difference. Formula III is the best formula because the resulting preparation is homogeneous, PH is 5, viscosity is 2.4 cP, the preparation is stable and formula III has the best antibacterial activity.
Antifungal activity of shampoo formulated with water spinach (Ipomoea aquatica) ethanolic extract against Pityrosporum ovale Aisali, Ledyta Asa; Genatrika, Erza; Budiman, Arif
Acta Pharmaciae Indonesia Vol 12 No 1 (2024): Acta Pharmaciae Indonesia: Acta Pharm Indo
Publisher : Pharmacy Department, Faculty of Health Sciences, Jenderal Soedirman University, Purwokerto, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20884/1.api.2024.12.1.12011

Abstract

Background: Dandruff, primarily caused by Pityrosporum ovale, is a common scalp disorder, especially in tropical regions. Natural alternatives, such as water spinach (Ipomoea aquatica), are increasingly being explored for their antimicrobial properties due to their minimal side effects. Objective: This study aimed to formulate an anti-dandruff shampoo using ethanol extract of water spinach and evaluate its physical properties and antifungal activity against P. ovale. Results: The phytochemical screening of the water spinach extract confirmed the presence of polyphenols, flavonoids, and quinones, known for their antimicrobial properties. The shampoo formulations met pH and foam height standards and remained organoleptically stable over 28 days. However, viscosity decreased below the standard (<400 cps) after 28 days. The 4% extract formulation (F3) showed the highest antifungal activity with an inhibition zone of 10.01 mm, significantly greater than the negative control (p<0.05). Conclusion: Water spinach ethanol extract can be successfully formulated into a shampoo that meets most physical requirements and exhibits antifungal activity against P. ovale. The 4% extract formulation demonstrated the highest effectiveness, though viscosity stability requires further optimization.
Pengaruh Konseling Apoteker pada Pasien Prolanis Hipertensi Terhadap Penurunan Tekanan Darah dan Kepatuhan Minum Obat Setyaningsih, Ike Budi; Hapsari, Indri; Genatrika, Erza
Syntax Literate Jurnal Ilmiah Indonesia
Publisher : Syntax Corporation

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36418/syntax-literate.v10i9.61490

Abstract

Penyakit hipertensi di provinsi Jawa Tengah menempati proporsi terbesar yaitu 76,5% kasus baru dan menjadi prioritas utama dalam pengendalian penyakit tidak menular, di tambah dengan ketidakpatuhan pasien terhadap modifikasi gaya hidup dan pengobatan menjadi hambatan yang menyebabkan tidak efektifnya pengelolaan hipertensi sehingga berrisiko pada kejadian kardiovaskular dan stroke. Penelitian ini bertujuan menganalisis pengaruh konseling apoteker terhadap penurunan tekanan darah dan peningkatan kepatuhan minum obat pasien Prolanis hipertensi di Puskesmas Kabupaten Pemalang. Metode penelitian ini dengan pendekatan kuatitatif jenis Quasi Experimental control group design with pretest and posttest dengan kuesioner (MARS-5). Sampel penelitian berjumlah 50 dari dua perlakuan. Analisis data uji univariat, bivariat, validitas dan reliabilitas, dengan software SPSS versi 25. Hasil penelitian menunjukkan bahwa konseling apoteker efektif menurunkan tekanan darah dan meningkatkan kepatuhan minum obat pada pasien Prolanis hipertensi di Puskesmas Kabupaten Pemalang. Edukasi dari apoteker berperan penting dalam mendorong perubahan perilaku pasien, sehingga mendukung pengendalian hipertensi dan keberhasilan terapi secara berkelanjutan. Penelitian ini mendukung teori edukasi kefarmasian dan menyarankan pelibatan aktif apoteker dalam konseling Prolanis secara berkelanjutan.
In-Use Stability Sediaan Injeksi Hidrokortison di Rumah Sakit Rujukan Daerah Jawa Tengah Genatrika, Erza; Sundhani, Elza; Fitri, Adriana Eka
Jurnal Ilmiah Medicamento Vol 11 No 2 (2025): Jurnal Ilmiah Medicamento
Publisher : Fakultas Farmasi Universitas Mahasaraswati Denpasar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36733/medicamento.v11i2.11538

Abstract

Hydrocortisone Sodium Succinate 50mg injection is widely used in perinatology wards. These wards cater to newborns (0-28 days), low birth weight (<2.5 kg), or premature babies (<37 weeks), requiring special handling. The use of this injection requires a very small dose, so one vial of hydrocortisone injection can be used for more than one patient. Therefore, the remainder of this hydrocortisone injection is often stored for 24 hours in the refrigerator which will later be reused on other patients. This study aims to determine the in-use stability of hydrocortisone injection stored for 24 hours at 4oC and 25oC. This is certainly to improve patient safety. The data collection technique uses an observational method on hydrocortisone injection samples with 3 replications. In-use stability is assessed from the results of organoleptic tests, pH tests, viscosity tests, determination of drug levels using UV-VIS spectrophotometry and sterility tests. Testing was conducted on days 0, 1, 2, 3, 7, 14 and 30. The results of the study showed that hydrocortisone injection preparations stored for 1 day at 4°C or 25°C in the perinatology ward were no longer physicochemically stable (concentration). Chemical degradation began on day 1, then microbial contamination occurred immediately after completion of compounding in the ward (day 0). This is because reconstitution was not carried out in a clean room in accordance with USP <797>. It can be concluded that hydrocortisone injection preparations prepared in this hospital are not recommended for administration to patients after 1 day of storage and must be compounded in a clean room.
Diversifikasi Produk Kopi melalui Pelatihan Pembuatan Permen Jeli Kopi-Jahe pada Kedai Kopi Kopirasi Sirampog: Diversification of Processed Coffee Products through Training on Making Ginger-Coffee Jelly Candy at Kopirasi Coffee Shop Sirampog Raharjo, Aditya Singgih; Biky, Muhammad Amir; Genatrika, Erza; Hasyyati, Uqie Shabrina
Jurnal Pengabdian dan Pengembangan Masyarakat Indonesia Vol. 4 No. 2 (2025)
Publisher : Media Publikasi Cendekia Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56303/jppmi.v4i2.995

Abstract

Kopi merupakan salah satu komoditas unggulan Indonesia dengan potensi lokal di Sirampog, Brebes, di mana UMKM seperti Kedai Kopi Kopirasi berperan penting dalam perekonomian. Namun, bisnis ini menghadapi keterbatasan produk olahan sehingga rentan terhadap fluktuasi pasar. Kegiatan pengabdian masyarakat ini bertujuan untuk mendiversifikasi produk olahan kopi di Kedai Kopi Kopirasi melalui introduksi permen jeli kopi-jahe. Metode pelaksanaan terdiri dari pelatihan secara langsung dan pendampingan mengenai pembuatan permen jeli kopi-jahe, serta pemberian hibah peralatan produksi. Hasil kegiatan menunjukkan bahwa mitra telah berhasil memproduksi permen jeli dengan tekstur, rasa, dan aroma yang baik, serta memahami seluruh tahapan proses pembuatannya secara mandiri. Produk baru ini berpotensi meningkatkan nilai jual, menciptakan daya tarik konsumen baru, dan membuka sumber pendapatan tambahan bagi kedai. Sebagai rekomendasi, mitra disarankan untuk melakukan uji pasar secara terbatas, mengembangkan kemasan yang menarik, serta mengeksplorasi varian rasa lain untuk meningkatkan daya saing produk dalam jangka panjang
Implementasi dan Efektivitas Sistem Unit Dose Dispensing Dalam Meningkatkan Keselamatan Pasien di Rumah Sakit Wijayanto, Yayat; Wahyono, Djoko; Genatrika, Erza
Syntax Literate Jurnal Ilmiah Indonesia
Publisher : Syntax Corporation

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36418/syntax-literate.v10i5.58259

Abstract

Sistem Unit Dose Dispensing (UDD) merupakan inovasi dalam distribusi obat yang terbukti mampu meningkatkan keselamatan pasien di rumah sakit dengan mengurangi kesalahan pemberian obat. Penelitian ini bertujuan mengeksplorasi implementasi dan efektivitas UDD di rumah sakit Indonesia serta mengidentifikasi tantangan dan solusi yang relevan. Metode yang digunakan adalah narrative review dengan menganalisis data dari jurnal ilmiah dan publikasi akademik lima tahun terakhir. Analisis dilakukan menggunakan pendekatan Miles dan Huberman melalui tiga tahap: reduksi data, penyajian data, dan penarikan kesimpulan. Hasil menunjukkan bahwa UDD secara signifikan menurunkan medication errors, meningkatkan efisiensi kerja tenaga kesehatan, serta memperbaiki kepatuhan terhadap protokol pengobatan. Selain itu, UDD berkontribusi dalam pengurangan pemborosan obat dan peningkatan pengelolaan stok farmasi. Namun, tantangan seperti keterbatasan teknologi, resistensi tenaga medis, dan biaya investasi masih menjadi hambatan utama. Penelitian ini menyoroti pentingnya integrasi UDD dengan sistem informasi manajemen farmasi, peningkatan pelatihan berkelanjutan, serta dukungan kebijakan yang adaptif terhadap konteks lokal. Studi ini memberikan kontribusi baru dengan menyajikan analisis menyeluruh dari sisi teknis, manajerial, dan budaya organisasi dalam penerapan UDD di Indonesia, yang selama ini belum banyak diteliti. Implikasi dari temuan ini dapat menjadi dasar dalam pengambilan keputusan strategis untuk meningkatkan keselamatan pasien dan efisiensi pelayanan rumah sakit secara berkelanjutan.
Pharmacist Counseling In Hypertensive Patients Setyaningsih, Ike Budi; Hapsari, Indri; Genatrika, Erza
Syntax Literate Jurnal Ilmiah Indonesia
Publisher : Syntax Corporation

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36418/syntax-literate.v10i7.61302

Abstract

Hypertension is a major public health concern, contributing significantly to morbidity and mortality worldwide. Poor adherence to antihypertensive medications and lack of patient knowledge remain critical challenges in hypertension management. Pharmacists play a vital role in addressing these issues through counseling and patient education. This study aims to analyze the impact of pharmacist counseling on medication adherence, patient knowledge, and blood pressure control among hypertensive patients. A literature review was conducted, utilizing peer-reviewed research articles published between 2019 and 2025 from databases such as PubMed, Scopus, ScienceDirect, and Google Scholar. Studies focusing on pharmacist counseling interventions in hypertension management were included, while duplicate or non-relevant studies were excluded. Data analysis followed a qualitative framework, including data reduction, data presentation, and conclusion drawing to identify significant patterns and trends. The results indicate that pharmacist-led counseling improves medication adherence, enhances patients' understanding of hypertension management, and contributes to better blood pressure control. Patients receiving pharmacist counseling demonstrate higher adherence rates, greater awareness of their condition, and a significant reduction in both systolic and diastolic blood pressure levels. Furthermore, pharmacist interventions promote lifestyle modifications, such as dietary adjustments, increased physical activity, and smoking cessation, further contributing to improved hypertension management. Despite these positive outcomes, challenges remain in implementing pharmacist counseling effectively due to healthcare system limitations, patient-related barriers, and resource constraints. This study highlights the need for stronger integration of pharmacists in hypertension care and further research into the long-term impact of pharmacist-led interventions.
Responsibility in Pharmaceutical Practice: Aplication of Beyond Use Date for Compounded Preparations Pratika Azzahra; Erza Genatrika
Journal of Pharmacopoeia Vol. 2 No. 1 (2025): MARCH-JP
Publisher : Pt. Anagata Sembagi Education

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62872/a7khyc44

Abstract

BUD (beyond use date) is very important to maintain the quality, safety, and effectiveness of the drug after the package is opened or blended. The purpose of this study is to evaluate the implementation of BUD (beyond use date) in various pharmaceutical facilities. This study uses the Systematic Literature Review (SLR) method. This study uses a database from scopus. There are three stages carried out in mapping evaluated the application of BUD (beyond use date) in various pharmaceutical facilities, namely : 1) harvesting data, 2) data screening, 3) data analysis and visualization. From the results of data harvesting, 8 articles were published. Based on research with the SLR method that has been carried out, it can be concluded that penerapan Beyond Use Date (BUD) In pharmaceutical preparations, it is a critical aspect that affects the stability, effectiveness, and safety of the drug for patients. Previous studies have shown that adherence to medical standards has a significant impact on the success of therapy. Therefore, this study emphasizes the need for better standardization, increased pharmacist compliance, as well as further research on the impact of the implementation of BUD in clinical pharmacy. The implications of this study are addressed to the researchers and the pharmaceutical practice.
Co-Authors Aditya Singgih Raharjo Adriana, Eka Fitri Aisali, Ledyta Asa Andi Nurul Annisa Anjar Mahardian Kusuma Annisa, Andi Nurul Annissya, Widia Primi Arif Budiman Asmiyenti Djaliasrin Djalil Bayu Satria Nugroho Putra Biky, Muhammad Amir Djoko Wahyono Dwi Hartanti Ferliati, Rosi Eka Fitri, Adriana Eka Hasyyati, Uqie Shabrina Ika Yuni Astuti Indri Hapsari Indri Hapsari Irma Nur Pahalawati Irmas Miranti Isna Nurkhikmah Ivani, Adhika Rifki Julyanti, Ai Rian Mayang Ika Oktaviana Ni Made Dharma Shantini Suena Nofita Fitri Kurniasih Pratama, Okta Nurandi Pratika Azzahra Puteri Khazizah Isnaini Rossy Faizah Nur Utami Setyaningrum, Nenden Setyaningsih, Ike Budi Siti Musyarofah Sundhani, Elza Susanti, Susanti Tika Ambarwati Trisna Rohmiyati Wahyu Utaminingrum Widyowati, Ulfi Wijayanto, Yayat Yola Anggraeni Zainur Rahman Hakim