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Pengaruh Home Care Apoteker terhadap Kepatuhan Pasien Hipertensi Utaminingrum, Wahyu; Pranitasari, Resita; Kusuma, Anjar M.
Indonesian Journal of Clinical Pharmacy Vol 6, No 4 (2017)
Publisher : Indonesian Journal of Clinical Pharmacy

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (173.61 KB) | DOI: 10.15416/ijcp.2017.6.4.240

Abstract

Berdasarkan data Riset Kesehatan Dasar tahun 2013, prevalensi hipertensi mencapai 25,8%. Hipertensi dapat dikontrol dengan meminum obat secara rutin dan gaya hidup sehat. Salah satu faktor yang dapat meningkatkan keberhasilan terapi hipertensi adalah kepatuhan pasien dalam meminum obat. Home care yang dilaksanakan oleh apoteker berupa pelayanan kefarmasian yang bersifat kunjungan rumah diharapkan dapat memberikan edukasi dan pemahaman pasien terhadap terapi hipertensi sekaligus memastikan bahwa pasien telah meminum obat dengan tepat, sehingga dengan home care dapat meningkatkan kepatuhan pasien dalam meminum obat. Tujuan penelitian ini adalah untuk menilai pengaruh home care yang dilakukan apoteker terhadap kepatuhan pasien hipertensi dalam meminum obat. Penelitian ini menggunakan desain eksperimental dan melibatkan 70 pasien hipertensi yang merupakan anggota Program Pengelolaan Penyakit Kronis dari 7 dokter keluarga di Kabupaten Banyumas, Propinsi Jawa Tengah. Pasien dibagi menjadi 2 kelompok, yaitu kelompok kontrol (35 pasien) dan kelompok home care (35 pasien) yang ditentukan secara acak. Seluruh pasien mendapatkan informasi standar mengenai penggunaan obat antihipertensi. Home care merupakan intervensi yang dilakukan dengan memberikan informasi tentang penyakit hipertensi, pengobatan hipertensi secara farmakologi dan non-farmakologi. Intervensi tersebut dilakukan satu kali pada hari ke-15 oleh apoteker dengan berkunjung ke rumah pasien selama 10 sampai 20 menit di rumah pasien. Pill count digunakan untuk mengukur kepatuhan pasien meminum obat dengan cara menghitung sisa obat pada hari ke-30. Hasil analisis Chi-Square test menunjukkan terdapat pengaruh intervensi terhadap kepatuhan minum obat p=0,000 (p<0,05). Dapat disimpulkan bahwa terdapat pengaruh home care terhadap kepatuhan pasien hipertensi.Kata kunci: Hipertensi, home care, kepatuhan Effect of Pharmacist Home Care on Adherence of Hypertensive PatientsBased on data from Basic Health Research on 2013, the prevalence of hypertension was up to 25.8%. Hypertension can be controlled by taking medication regularly and healthy lifestyle. Factor that can improve the success of the treatment of hypertension is patient adherence in taking medicines. Home pharmacy care by pharmacist was expected to provide education and understanding of therapy also ensure that patients can take the medicine properly, therefore it can improve patient adherence in taking medicine. The aim of this research was to determine the effect of pharmacist home care on antihypertensive patients adherence in taking medicine. Experimental research design was used in this research. There were 70 hypertensive patients involved who were members of Chronic Disease Management Program from 7 general practitioners in Banyumas, Central Java. The participants were divided into control group (35 patients) and home care group (35 patients). All of the participants received standard information about antihypertensive drugs usage. Pharmacist home care was an intervention which done at 15th day by giving information about hypertension, pharmacology and non-pharmacology treatment for 10-20 minutes at patient’s house. Pill count was used to measure patient adherence to antihypertensive drugs used at 30th day. According to statistical analysis by Chi-Square test, we obtained the value p= 0.000 (p<0.05). It can be concluded that there was pharmacist home care effect on antihypertensive patients adherence (p=0.000).Keywords: Hypertension, home care, adherence
Evaluasi Kuantitatif Penggunaan Antibiotik pada Pasien Caesarean Section di RSUD se-Kabupaten Banyumas Kusuma, Anjar Mahardian; Galistiani, Githa Fungie; Wijayanti, Dwi Nur; Umami, Muzayanatul; Nurdiyanti, .; Utaminingrum, Wahyu; Sudarso, .
JFIOnline | Print ISSN 1412-1107 | e-ISSN 2355-696X Vol 8, No 1 (2016)
Publisher : Indonesian Research Gateway

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

ABSTRACT : Antibiotics usage in woman having caesarean section is assumed 5-fold greater than woman having normal labor. The aim of the study is to count the antibiotics usage in patient having caesaren section in several hospitals in Banyumas, i.e. RSUD Prof. DR. Margono Soekarjo, RSUD Ajibarang, and RSUD Banyumas. This study use cross sectional study design, retrospective data collection of medical records and data were statistically analyzed with Mann- Whitney and Kruskal-Wallis. Results of the study showed that the greatest quantity of antibiotic use was in RSUD Ajibarang with 110.75 DDD/100 patient- days, followed by RSUD Prof. DR Margono Soekarjo and RSUD Banyumas respectively 76.20 DDD/100 patient-days and 46.07 DDD/100 patient-day. The comparison of DDD for each antibiotic in three hospitals showed a significant difference on antibiotic amoxicillin and cefotaxime usage. Keywords : antibiotics, DDD, caesarean section ABSTRAK : Penggunaan antibiotik pada pasien caesarean section diperkirakan 5 kali lipat lebih banyak dibandingkan pada persalinan normal. Penelitian ini bertujuan untuk menghitung kuantitas penggunaan antibiotik terapi pada pasien caesarean section di beberapa rumah sakit di kabupaten Banyumas, yaitu RSUD Prof. DR. Margono Soekarjo, RSUD Ajibarang, dan RSUD Banyumas. Penelitian ini menggunakan rancangan studi potong lintang (cross sectional), pengambilan data dilakukan secara retrospektif terhadap rekam medik dan data dianalisis dengan analisis statistik Man-Whitney and Kruskal-Wallis. Dari hasil penelitian ini diperoleh data bahwa kuantitas penggunaan antibiotik terbesar terjadi di RSUD Ajibarang yakni 110,75 DDD/100 pasien-hari kemudian diikuti RSUD Prof. DR. Margono Soekarjo dan RSUD Banyumas dengan masing-masing 76,20 DDD/100 pasien-hari dan 46,07 DDD/100 pasien-hari. Hasil perbandingan DDD tiap antibiotik di tiga rumah sakit menunjukkan adanya perbedaan bermakna nilai DDD antibiotik amoksisilin dan sefotaksim di tiga rumah sakit tersebut. Kata kunci: antibiotik, DDD, caesarean section
Evaluasi Kuantitatif Penggunaan Antibiotik pada Pasien Caesarean Section di RSUD se-Kabupaten Banyumas Kusuma, Anjar Mahardian; Galistiani, Githa Fungie; Wijayanti, Dwi Nur; Umami, Muzayanatul; Nurdiyanti, .; Utaminingrum, Wahyu; Sudarso, .
Jurnal Farmasi Indonesia Vol 8, No 1 (2016)
Publisher : Jurnal Farmasi Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (210.912 KB) | DOI: 10.35617/jfi.v8i1.245

Abstract

ABSTRACT : Antibiotics usage in woman having caesarean section is assumed 5-fold greater than woman having normal labor. The aim of the study is to count the antibiotics usage in patient having caesaren section in several hospitals in Banyumas, i.e. RSUD Prof. DR. Margono Soekarjo, RSUD Ajibarang, and RSUD Banyumas. This study use cross sectional study design, retrospective data collection of medical records and data were statistically analyzed with Mann- Whitney and Kruskal-Wallis. Results of the study showed that the greatest quantity of antibiotic use was in RSUD Ajibarang with 110.75 DDD/100 patient- days, followed by RSUD Prof. DR Margono Soekarjo and RSUD Banyumas respectively 76.20 DDD/100 patient-days and 46.07 DDD/100 patient-day. The comparison of DDD for each antibiotic in three hospitals showed a significant difference on antibiotic amoxicillin and cefotaxime usage. Keywords : antibiotics, DDD, caesarean section ABSTRAK : Penggunaan antibiotik pada pasien caesarean section diperkirakan 5 kali lipat lebih banyak dibandingkan pada persalinan normal. Penelitian ini bertujuan untuk menghitung kuantitas penggunaan antibiotik terapi pada pasien caesarean section di beberapa rumah sakit di kabupaten Banyumas, yaitu RSUD Prof. DR. Margono Soekarjo, RSUD Ajibarang, dan RSUD Banyumas. Penelitian ini menggunakan rancangan studi potong lintang (cross sectional), pengambilan data dilakukan secara retrospektif terhadap rekam medik dan data dianalisis dengan analisis statistik Man-Whitney and Kruskal-Wallis. Dari hasil penelitian ini diperoleh data bahwa kuantitas penggunaan antibiotik terbesar terjadi di RSUD Ajibarang yakni 110,75 DDD/100 pasien-hari kemudian diikuti RSUD Prof. DR. Margono Soekarjo dan RSUD Banyumas dengan masing-masing 76,20 DDD/100 pasien-hari dan 46,07 DDD/100 pasien-hari. Hasil perbandingan DDD tiap antibiotik di tiga rumah sakit menunjukkan adanya perbedaan bermakna nilai DDD antibiotik amoksisilin dan sefotaksim di tiga rumah sakit tersebut. Kata kunci: antibiotik, DDD, caesarean section
Pengaruh Home Care Apoteker terhadap Kepatuhan Pasien Hipertensi Wahyu Utaminingrum; Resita Pranitasari; Anjar M. Kusuma
Indonesian Journal of Clinical Pharmacy Vol 6, No 4 (2017)
Publisher : Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (1588.895 KB) | DOI: 10.15416/ijcp.2017.6.4.240

Abstract

Berdasarkan data Riset Kesehatan Dasar tahun 2013, prevalensi hipertensi mencapai 25,8%. Hipertensi dapat dikontrol dengan meminum obat secara rutin dan gaya hidup sehat. Salah satu faktor yang dapat meningkatkan keberhasilan terapi hipertensi adalah kepatuhan pasien dalam meminum obat. Home care yang dilaksanakan oleh apoteker berupa pelayanan kefarmasian yang bersifat kunjungan rumah diharapkan dapat memberikan edukasi dan pemahaman pasien terhadap terapi hipertensi sekaligus memastikan bahwa pasien telah meminum obat dengan tepat, sehingga dengan home care dapat meningkatkan kepatuhan pasien dalam meminum obat. Tujuan penelitian ini adalah untuk menilai pengaruh home care yang dilakukan apoteker terhadap kepatuhan pasien hipertensi dalam meminum obat. Penelitian ini menggunakan desain eksperimental dan melibatkan 70 pasien hipertensi yang merupakan anggota Program Pengelolaan Penyakit Kronis dari 7 dokter keluarga di Kabupaten Banyumas, Propinsi Jawa Tengah. Pasien dibagi menjadi 2 kelompok, yaitu kelompok kontrol (35 pasien) dan kelompok home care (35 pasien) yang ditentukan secara acak. Seluruh pasien mendapatkan informasi standar mengenai penggunaan obat antihipertensi. Home care merupakan intervensi yang dilakukan dengan memberikan informasi tentang penyakit hipertensi, pengobatan hipertensi secara farmakologi dan non-farmakologi. Intervensi tersebut dilakukan satu kali pada hari ke-15 oleh apoteker dengan berkunjung ke rumah pasien selama 10 sampai 20 menit di rumah pasien. Pill count digunakan untuk mengukur kepatuhan pasien meminum obat dengan cara menghitung sisa obat pada hari ke-30. Hasil analisis Chi-Square test menunjukkan terdapat pengaruh intervensi terhadap kepatuhan minum obat p=0,000 (p<0,05). Dapat disimpulkan bahwa terdapat pengaruh home care terhadap kepatuhan pasien hipertensi.Kata kunci: Hipertensi, home care, kepatuhan Effect of Pharmacist Home Care on Adherence of Hypertensive PatientsBased on data from Basic Health Research on 2013, the prevalence of hypertension was up to 25.8%. Hypertension can be controlled by taking medication regularly and healthy lifestyle. Factor that can improve the success of the treatment of hypertension is patient adherence in taking medicines. Home pharmacy care by pharmacist was expected to provide education and understanding of therapy also ensure that patients can take the medicine properly, therefore it can improve patient adherence in taking medicine. The aim of this research was to determine the effect of pharmacist home care on antihypertensive patient's adherence in taking medicine. Experimental research design was used in this research. There were 70 hypertensive patients involved who were members of Chronic Disease Management Program from 7 general practitioners in Banyumas, Central Java. The participants were divided into control group (35 patients) and home care group (35 patients). All of the participants received standard information about antihypertensive drugs usage. Pharmacist home care was an intervention which done at 15th day by giving information about hypertension, pharmacology and non-pharmacology treatment for 10-20 minutes at patient’s house. Pill count was used to measure patient adherence to antihypertensive drugs used at 30th day. According to statistical analysis by Chi-Square test, we obtained the value p= 0.000 (p<0.05). It can be concluded that there was pharmacist home care effect on antihypertensive patient's adherence (p=0.000).Keywords: Hypertension, home care, adherence
Traditional Use of Medicinal Plants in Baturraden, Central Java Nofrianti Nofrianti; Wahyu Utaminingrum; Dwi Hartanti
Jurnal Jamu Indonesia Vol. 6 No. 2 (2021): Jurnal Jamu Indonesia
Publisher : Tropical Biopharmaca Research Center, IPB University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29244/jji.v6i2.206

Abstract

An ethnopharmacological study is an initial step for the development of jamu, which has been simultaneously conducted throughout Indonesia. This study aimed to explore the utilization of medicinal plants in Baturraden, a region with relatively rich plant biodiversity in Java. Our research is a quantitative ethnobotanical study reporting the utilization of medicinal plants as a single plant botanical preparation in the studied area. The data were collected through semi-structured interviews with 36 informants on the local names, indications, parts used, method of preparation, and application of the plants. The species use-value (SUV), relative frequency citation (RFC), and the fidelity level (FL) of each species were calculated accordingly. The study recorded the utilization of 47 species of medicinal plants, which were employed to treat 32 ailments. Leaves, decoctions, and oral were recorded as the most commonly used plant part, herbal preparation, and application. There were 24 botanical preparations with the FL value of 100%, which were indicated for the treatment of fourteen diseases/symptoms. Curcuma longa, Zingiber officinale, Piper betle, Cymbopogon citratus, Andrographis paniculata, Syzygium polyanthum, Citrus aurantiaca, and Zingiber montanum were considered as the most important and valuable plants by the local community. Hence, those plants should be evaluated further for their pharmacological activity and developed into standardized botanical preparations.
EVALUASI MANAJEMEN PENGELOLAAN OBAT DI PUSKESMAS RAWAT INAP KABUPATEN PURBALINGGA BERDASARKAN TIGA BESAR ALOKASI DANA PENGADAAN OBAT R. Adi Soeprijanto; Indri Hapsari; Wahyu Utaminingrum
PHARMACY: Jurnal Farmasi Indonesia (Pharmaceutical Journal of Indonesia) Jurnal Pharmacy, Vol. 08 No. 03 Desember 2011
Publisher : Pharmacy Faculty, Universitas Muhammadiyah Purwokerto

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30595/pji.v8i03.1126

Abstract

ABSTRAK Telah dilakukan penelitian tentang Evaluasi Manajemen Pengelolaan Obat di Puskesmas Rawat Inap Kabupaten Purbalingga Berdasarkan Tiga Besar Alokasi Dana Pengadaan Obat. Tujuan dari penelitian ini adalah untuk mengevaluasi manajemen pengelolaan obat di Puskesmas Rawat Inap Kabupaten Purbalingga berdasarkan 3 besar alokasi dana pengadaan obat. Penelitian ini dilakukan menggunakan metode deskriptif dengan pendekatan kualitatif dan didukung dengan data kuantitatif. Sampel yang diambil adalah Puskesmas Kalimanah, Puskesmas Bobotsari dan Puskesmas Rembang. Hasil penelitian menunjukkan bahwa Puskesmas dalam melakukan perencanaan tergolong tidak baik. Stok optimum tidak tercatat pada kartu stok dan masih terdapat permintaan obat diluar DOEN untuk Puskesmas Kalimanah sebesar 84,51%, Puskesmas Bobotsari 79,64% dan Puskesmas Rembang 85,35%. Penerimaan obat sudah dilakukan dengan ketentuan yang berlaku. Penyimpanan Psikotropika belum sesuai ketentuan dan belum menjamin mutu obat. Distribusi obat, pengendalian penggunaan, pencatatan dan pelaporan sudah dilakukan sesuai dengan ketentuan. Kata kunci : Evaluasi, Pengelolaan Obat, Puskesmas Rawat Inap, Alokasi Dana Obat. ABSTRACT A research about Evaluation of Drug Management in Public Health Centre with Lodge Care of Purbalingga Based on Three Major of Public Sector Drug. The purpose of this study to evaluate management of drug in Public Health Centre with lodge care of Purbalingga based on three major of public sector drug. This research use descriptive method with approach qualitative which supported with quantitative data. The sample’s of this research are Public Health Centre of Kalimanah, Bobotsari and Rembang. The result of research show that Public Health Centre in planning was not good. Optimum stock is not be noted at stock card and there are still requested of drug outside DOEN for the Public Health Centre of Kalimanah 84,51%, Bobotsari 79,64% and Rembang 85,35%. Acceptance of drug have been done with procedure. Storing of Psikotropika drug is not according the rule and not guarantee the quality of drug. Drug distribution, operation of usage, reporting and record-keeping have been done with procedure. Key words : Evaluation, Drug Management, Public Health Centre with lodge care, Public Sector Drug.
TINGKAT KEPUASAN KONSUMEN APOTEK DI KABUPATEN BANJARNEGARA Tri Setianingrum; Sudarso Sudarso; Wahyu Utaminingrum
PHARMACY: Jurnal Farmasi Indonesia (Pharmaceutical Journal of Indonesia) Jurnal Pharmacy, Vol. 08 No. 03 Desember 2011
Publisher : Pharmacy Faculty, Universitas Muhammadiyah Purwokerto

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30595/pji.v8i03.1131

Abstract

ABSTRAK Telah dilakukan penelitian tentang tingkat kepuasan konsumen apotek di Kabupaten Banjarnegara. Tujuan penelitian ini adalah untuk mengetahui tingkat kepuasan konsumen di apotek Kabupaten Banjarnegara. Penelitian ini merupakan penelitian deskriptif analitik dengan model pendekatan secara observasional. Pengambilan sampel untuk penelitian ini menggunakan metode area random sampling dengan sampel berjumlah 400 orang konsumen. Metode pengumpulan data dilakukan dengan menggunakan kuesioner dan dianalisis dengan metode customer satisfaction index (CSI). Hasil analisis menunjukkan nilai customer satisfaction index (CSI) pada dimensi Responsiveness sebesar 0,8324 termasuk kategori sangat puas, pada dimensi assurance sebesar 0,8242 termasuk kategori sangat puas, pada dimensi reliability sebesar 0,7189 termasuk kategori puas, pada dimensi tangible sebesar 0,7704 termasuk kategori puas dan pada dimensi empathy sebesar 0,6194 termasuk kategori cukup puas. Nilai CSI secara keseluruhan sebesar 0,695 berada pada rentang nilai 0,66-0,80 yang termasuk kategori puas. Tingkat kepuasan konsumen apotek Kabupaten Banjarnegara adalah puas. Kata kunci : Tingkat kepuasan konsumen, pelayanan kefarmasian, apotek. ABSTRACT Has done research on the level of consumer satisfaction in the district of Banjarnegara pharmacies. The purpose of this study was to determine the level of consumer satisfaction in pharmacies Banjarnegara district. This research is descriptive analytical model with the observational approach. Sampling for this study using random sampling method with sample areas totaling 400 people of consumers. Methods of data collection is done by using a questionnaire and analyzed by the method of customer satisfaction index (CSI). The analysis showed the value of customer satisfaction index (CSI) on the dimensions of 0.8324 Responsiveness including categories very satisfied, on the assurance dimension of 0.8242 including the category of very satisfied, on the dimensions of reliability of 0.7189, including categories of content, on tangible dimension of 0 , 7704 including the categories of satisfaction and the dimensions of empathy for 0.6194 categorized quite satisfied. CSI overall value of 0.695 is in the range of values from 0.66 to 0.80 are categorized as satisfied. Levels of consumer satisfaction pharmacy Banjarnegara District is satisfied. Keywords: Level of customer satisfaction, pharmacy services, pharmacy.
EVALUASI PENGGUNAAN OBAT PADA PASIEN SKIZOPRENIA DI INSTALASI RAWAT INAP RUMAH SAKIT UMUM DAERAH BANYUMAS PERIODE JANUARI –APRIL 2009 Gayuh Kurniawan; Indri Hapsari; Wahyu Utaminingrum
PHARMACY: Jurnal Farmasi Indonesia (Pharmaceutical Journal of Indonesia) Jurnal Pharmacy, Vol. 08 No. 03 Desember 2011
Publisher : Pharmacy Faculty, Universitas Muhammadiyah Purwokerto

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30595/pji.v8i03.1136

Abstract

ABSTRAK Skizofrenia merupakan gangguan psikiatrik yang sangat kompleks yang dapat menimbulkan paling banyak masalah baik medik, psikologik maupun social. Penelitian ini dilakukan dengan menggunakan rancangan deskriptif non analitik yang bersifat retrospektif. Tujuan penelitian ini untuk mengetahui karakteristik pasien (jenis kelamin, usia, status pendidikan, durasi rawat inap dan keadaan pulang pasien), pola pengobatan dan kesesuaian terapi (jenis obat, dosis obat dan cara pemberian) dengan Standar Pelayanan Medis (SPM), dan mengetahui interaksi obat yang terjadi. Hasil dari penelitian ini, karakteristik pasien (jenis kelamin 63,49% pada wanita, usia 31,75% 20-29 tahun, status pendidikan SD 31,7%, durasi rawat inap 30,1% 7-14 hari, keadaan pulang pasien 88% membaik), pola pengobatan (jenis obat 80,16%, dosis obat 78,57%, cara pemberian 91,27%), kesesuaian terapi (jenis obat 73,01%, dosis obat 78,57%, cara pemberian 96,03%) dan interaksi yang terjadi adalah interaksi antar obat skizofrenia (100 kasus) dan interaksi obat skizofrenia dengan obat lain (34 kasus). Kata kunci : Skizofrenia, Retrospektif, Standar Pelayanan Medis (SPM), Karakteristik pasien, Pola Pengobatan, Kesesuaian Terapi ABSTRACT Schizophrenia represent the very complex trouble psychiatric which can generate at most good problem sis, psychology and also social. This research conducted by using descriptive device non-analytic having the character of retrospective. This research target to know the patient characteristic (gender, age, education status, time take care to lodge and circumstance come home the patient), medication pattern and according to therapy (drug type, dose medicines and way of gift) with the Medical Service Standard (SPM), and know the interaction medicines that happened. Result from this research, patient characteristic (gender 63,49% at woman, age 31,75% 20-29 year, status education SD 31,7%, time take care to lodge 30,1% 7-14 day, circumstance come home the patient 88% good), medication pattern (type medicines 80,16%, dose medicines 78,57%, way gift 91,27%), according to therapy (type medicines 73,01%, dose medicines 78,57%, way gift 96,03%) and interaction that happened interaction usher the drug schizophrenia (100 case) and interaction medicines the schizophrenia with the other drug (34 case). Keyword : Schizophrenia, Retrospective, Medical Service Standard (SPM), Patient Characteristic, Medication Pattern, According to Therapy, Drug Interaction.
EVALUASI POLA PERESEPAN BERDASARKAN BEERS CRITERIA PADA PASIEN GERIATRI RAWAT JALAN PADA POLI PENYAKIT DALAM DI RSUD Prof. Dr. MARGONO SOEKARJO PURWOKERTO PERIODE AGUSTUS 2010-MARET 2011 Dhian Rahayu Setyowati; Sudarso Sudarso; Wahyu Utaminingrum
PHARMACY: Jurnal Farmasi Indonesia (Pharmaceutical Journal of Indonesia) Jurnal Pharmacy, Vol. 08 No. 03 Desember 2011
Publisher : Pharmacy Faculty, Universitas Muhammadiyah Purwokerto

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30595/pji.v8i03.1127

Abstract

ABSTRAK Geriatri berasal dari kata geros yang berarti tua dan iatriea yang berarti to care atau merawat. WHO menetapkan populasi antara usia 65-75 tahun sebagai geriatri. Pada usia ini, terjadi penurunan fungsi-fungsi fisiologis tubuh sehingga diperlukan pertimbangan yang cermat dalam memilih obat. Beers Criteria merupakan suatu kriteria yang menjadi standar penggunaan obat khusus untuk geriatri, yang mengetengahkan dasar panduan untuk mengatasi masalah Drug Related Problem (DRP) pada geriatri. Penelitian ini adalah untuk mengevaluasi pola peresepan pada pasien geriatri rawat jalan pada poli penyakit dalam di RSUD Prof. Dr. Margono Soekarjo Purwokerto berdasarkan Beers Criteria 2003 dan melihat persentase ketidakrasionalan peresepan pada pasien geriatri rawat jalan penyakit dalam periode Agustus 2010 – Maret 2011. Metode yang digunkan adalah non eksperimental, dengan pengumpulan data secara retrospektif. Analisis dilakukan dengan metode diskriptif untuk memperoleh gambaran tentang pola peresepan pasien geriatri rawat jalan di poli penyakit dalam berdasarkan Beers Criteria 2003. Hasil yang diperoleh menunjukkan bahwa selama periode Agustus 2010 – Maret 2011, dari total 405 item obat terdapat 84 item obat (20,5%) yang tidak rasional yang sesuai Beers Criteria 2003. Obat yang paling banyak diresepkan sekaligus dihindarkan adalah diazepam yaitu 26 item obat (31,3 %), Chlordiazepoksid-clidinium 25 item obat (30,1%), Digoxin 24 item obat (27,7%), Alprazolam 6 item obat (7,1%), Ferrosi Sulfat 1 item obat (1,2%), Bisakodil 1 item obat (1,2%), Clonidine 1 item obat (1,2%). Kata kunci: geriatri rawat jalan poli penyakit dalam, beers criteria 2003 ABSTRACT Geriatric derived from the word geros is meaning oldest and iatriea is meaning to care. WHO set the population between the ages of 65-75 years as a geriatric ward. At this age, a decline of physiological functions of the body so that needed careful consideration in choosing a drug. Beers Criteria is a standard criteria to be specific to geriatric drug use. Beers Criteria specifically set forth basic guidelines for the surpass Drug Related Problem in geriatrics. Goal of the research is evaluating of prescription patterns in geriatric outpatient based on Beers Criteria in Geriatrics outpatient on internist division regional public hospital of Prof. Dr. Margono Soekarjo Purwokerto and all at once to see irrasionalist praescription patterns in geriatric outpatient in August 2010 to March 2011 period. The method`used was non experimental, with retrospective data collection. The analysis was done with descriptive method to get an idea of prescription patterns in geriatric outpatient on internist division based on Beers Criteria 2003. Results obtained show that during August 2010 to March 2011 period, of total 425 recipe there are 84 recipe (19,8%) that is not appropriate rational Beers Criteria 2003. The most widely prescribed drugs were diazepam 26 drug item (31,0 %), Chlordiazepoksid-clidinium 25 drug item (29,8%), Digoxin 24 drug item (28,6%), Alprazolam 6 drug item (7,1%), Ferrosi Sulfat 1 drug item (1,2%), Bisakodil 1 drug item (1,2%), Clonidine 1 drug item (1,2%) Keywords: geriatrics outpatient on internist division, beers criteria 2003
Uji Sensitisasi Dermal Masker Gel Kombinasi Ekstrak Ampas Daun Teh dan Air Cucian Beras Annisa, Andi Nurul; Utaminingrum, Wahyu; Genatrika, Erza
Jurnal Kefarmasian Indonesia VOLUME 9, NOMOR 1, FEBRUARI 2019
Publisher : Pusat Penelitian dan Pengembangan Biomedis dan Teknologi Dasar Kesehatan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22435/jki.v9i1.491

Abstract

The combination of tea leaf dregs extract and rice washing water as a peel-off gel mask was found to be stable up to 28 days of storage and had an IC50 value 20.4 ppm. This potential can provide an optimal effects as cosmetic ingredients.However, to meet the regulatory requirements of Badan Pengawas Obat Makanan (BPOM) RI and ISO 10993, a dermal sensitization test also need to be done. The aim of this study was to determine the dermal sensitization reaction from peel-off gel mask containing a combination of tea leaf dregsextract (Camellia sinensis L.) and rice washing water (Oryza sativa L.) in test animal. Thisstudy was designed based on experimental laboratory methods and sample selection by simple random sampling. The intervention was given based on posttest-only control group design. The test results for dermal sensitization were determined using the Guinea Pig Maximization Test (GPMT) method. The results showed erythema and edema reactions according to the Magnusson and Kligman scale after administration of peel-off gel masks as samples in the topical tests in test animals, appeared on the 11th day and in the challenge test appeared on the 24th day. This was due to incubation period for one week where the hypersensitivity state can develop, so that this reaction is also called the delayed hypersensitivity reaction