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All Journal Jurnal Gizi dan Pangan Journal Of Vocational Health Studies Buletin Farmatera PengabdianMu: Jurnal Ilmiah Pengabdian kepada Masyarakat Majalah Kedokteran Andalas Jurnal Abdimas Madani dan Lestari (JAMALI) Jurnal Ilmiah Kesehatan Masyarakat : Media Komunikasi Komunitas Kesehatan Masyarakat
Hardini, Niniek
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Agriculture, Biological Sciences & Forestry Humanities Civil Engineering, Building, Construction & Architecture Computer Science & IT Economics, Econometrics & Finance Health Professions Law, Crime, Criminology & Criminal Justice Medicine & Pharmacology Public Health Social Sciences Other

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Potential of Flavonoids on Aortic Histopathological Improvement of ApoE-/- Mice With High-Fat Diet: A Systematic Literature Review Adyatma, Hilmi; Hardini, Niniek; Thadeus, Maria Selvester
Buletin Farmatera Vol 6, No 2 (2021)
Publisher : Universitas Muhammadiyah Sumatera Utara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30596/bf.v6i2.6358

Abstract

Non-communicable diseases account for more than 36 million deaths every year (63% of all deaths). Globally, non-communicable diseases (NCDs) that cause the most deaths each year are cardiovascular diseases. One of the cardiovascular diseases is coronary heart disease. The cause of coronary heart disease is acute coronary syndrome. More than 90% of acute coronary syndromes (ACS) are the result of atherosclerotic disorders. Therefore, research on the potential of flavonoids to improve histopathology of atherosclerosis needs to be carried out in order to provide information about alternative drugs that can be used by patients. The purpose of this research using a systematic literature review research methodology is to identify the potential of flavonoids to improve aortic histopathology in ApoE-/- mice with a high-fat diet. Systematic literature review by conducting a literature search using PubMed and Google Scholar. Literature that discusses flavonoids, ApoE-/- mice, high-fat diet, aorta, and atherosclerosis. There were 8 studies which concluded that flavonoids could inhibit or reduce the enlargement or further formation of aortic atherosclerotic plaques in ApoE-/- mice on a high-fat diet. Flavonoids have the potential to inhibit or reduce the enlargement or further formation of aortic atherosclerotic plaques in ApoE-/- mice on a high-fat diet.
FLIGHT HOURS AND BMI AGAINST TUC IN HYPOBARIC CHAMBER ALTITUDE 25.000 FEET Nuralfilail, Zakiah Nada; Savitri, Pritha Maya; Hardini, Niniek; Chairani, Aulia; Andriyanto; Budi Maryoto, Agus; A., Samsul; Kardiana, Yaya; Cakrahaya, Agus
Journal of Vocational Health Studies Vol. 8 No. 1 (2024): July 2024 | JOURNAL OF VOCATIONAL HEALTH STUDIES
Publisher : Faculty of Vocational Studies, Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/jvhs.V8.I1.2024.7-12

Abstract

Background: Time of Useful Consciousness (TUC) is the time interval a person can survive carrying out flight duties due to a decrease in oxygen pressure and the point at which there is a decrease in the level of consciousness. The TUC time interval is influenced by various factors including Body Mass Index (BMI) and flying hours which affect the increase in the duration of the body's exposure to hypoxic conditions in pilots. Purpose: This research was conducted to determine the relationship between total flight hours and BMI on TUC. Method: This research employed observational analytic research with a cross-sectional method. Sampling was taken by simple random sampling technique. The sample for this research included active flight crew members from Lakespra dr. Saryanto 202 who met the inclusion criteria. Result: There were 53 research subjects, with the results showing that 48 subjects (90.6%) had a TUC <4 minutes, and 5 subjects had a TUC >4 minutes. There were 47 subjects (88.7%) with total flight hours >1000 hours and 6 subjects (11.3%) with total flight hours <1000 hours. In BMI, 37 subjects (69.8%) had an overweight BMI, and 16 subjects (30.2%) had a normal BMI. Conclusion: After examining 53 subjects, it was found that there was no relationship between total flight hours and TUC (p-value = 1.000) or BMI and TUC( p-value = 0.307) in the hypobaric chamber at an altitude of 25.000 feet.
Masa Kerja dan Lama Kerja Berhubungan dengan Keluhan Nyeri Punggung Bawah Pada Pengemudi Ojek Online Sunarya, Putri Amelia; Chairani, Aulia; Hardini, Niniek; Bustaman, Nurfitri
Jurnal Ilmiah Kesehatan Masyarakat : Media Komunikasi Komunitas Kesehatan Masyarakat Vol 16 No 3 (2024): JIKM Vol. 16, Edisi 3, Agustus 2024
Publisher : Public Health Undergraduate Program, Faculty of Health Science, Universitas Pembangunan Nasional Veteran Jakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52022/jikm.v16i3.642

Abstract

Background: Low back pain in Indonesia is the second highest illness after influenza. About 63 million (37%) Indonesians experience complaints of low back pain (LBP). NBP is a common problem in workers, including online motorcycle taxi drivers. Working positions that require online motorcycle taxi drivers to sit and support their body weight with vertebrae muscles and bones can cause muscle stiffness and spasm of vertebrae muscles, especially the lumbar part. Methods: Analytical quantitative research design using a cross-sectional approach. The sample of this study is an online motorcycle taxi driver with male gender, age 20-35 years and working > 3 months as an online motorcycle taxi driver, collected by consecutive sampling method. Result: Univariate results were obtained as much as NPB (60.2%), working >8 hours (61.3%) and working >1 year (64.5%). Bivariate results obtained a relationship between length of work (p value = 0.000) and tenure (p value = 0.000). Multivariate results show that the variable that most influences back pain complaints is the length of work (OR = 14.10). Conclusion: It is suggested that puskesmas frequently monitor and give counseling related to TB and the society clean their houses regularly and keep the house clean Keywords: low back pain, online motorcycle drivers, length of work, length of service
Sosialisasi Deteksi Dini dan Pengenalan Gejala Stadium Awal dan Akhir Kanker Serviks di Kecamatan Cinere: Indonesia Hardini, Niniek; Rifkia, Via; Wahyuni, Yosha Putri; Sukrisno, Adi
Jurnal Abdimas Madani dan Lestari (JAMALI) Volume 07, Issue 01, Maret 2025
Publisher : UII

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20885/jamali.vol7.iss1.art14

Abstract

Cervical cancer is a common cancer in women with an estimated 570,000 new cases in 2018 and represents 6.6% of all cancers in women. About 90% of cervical cancer deaths occur in low- and middle-income countries. High mortality rates from cervical cancer globally can be reduced through a comprehensive approach that includes prevention, early diagnosis, effective screening and treatment programs. Cervical cancer can be prevented with primary prevention. Primary prevention is to prevent the occurrence of Human Papillomavirus (HPV) infection with the advantage of not causing side effects, easy and effective. This prevention can be done using screening methods that are easy and inexpensive to do, such as Visual Inspection of Acetic Acid (IVA), which is visual inspection with acetic acid. The purpose of this activity is to increase knowledge about early detection of cervical cancer, symptoms at an early and late stage in Cinere Depok District. The assessment of understanding can be seen from the results of the pre-test and post-test. The results of this activity show that people in Cinere Depok District have understood the socialization of early detection of cervical cancer and recognize the symptoms of early and late stages of cervical cancer with an increase in the average value of post-test, which is 90% of the pre-test score.
The Therapeutic Effects of West Indian Elm (Guazuma ulmifolia) Leaf Extract on Coronary Artery Atherosclerosis in Hypercholesterolemic Wistar Rats Ramadhansyah, Reza; Thadeus, Maria Selvester; Muktamiroh, Hikmah; Hardini, Niniek
Jurnal Gizi dan Pangan Vol. 18 No. 2 (2023)
Publisher : The Food and Nutrition Society of Indonesia in collaboration with the Department of Community Nutrition, IPB University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25182/jgp.2023.18.2.109-116

Abstract

This study aimed to determine the therapeutic effect of West Indian elm leaf extract on coronary artery atherosclerosis in hypercholesterolemia Wistar rats. Cholesterol, a key factor in the pathophysiology of coronary heart disease, is present in fat-containing diets. Orlistat is one of the medications that can reduce blood cholesterol levels, but since it has side effects, herbs are more preferable to it. One such herbal plant, West Indian elm (Guazuma ulmifolia), contains tannins, saponins, alkaloids, and flavonoids, secondary metabolites that carry the properties necessary to reduce blood cholesterol levels, in its leaves. In this experimental study, which focused on histopathological parameters to see the scale of progression of coronary artery atherosclerosis, 30 Wistar rats were induced with a high-fat diet and divided into 6 sample groups, consisting of three control groups (normal, negative, and positive) and three treatment groups (which received a West Indian elm leaf extract at 0.2, 0.4, and 0.8 g/kgBW). Significant results were obtained from both Kruskal-Wallis and Mann-Whitney tests (p<0.05) between the negative control group and the positive control group, between the negative control group and treatment group 2 (0.4 g/kgBW), and between the negative control group and treatment group 3 (0.8 g/kgBW). In conclusion, this study proved that West Indian elm (Guazuma ulmifolia) leaf extract reduces the development of coronary atherosclerosis and shares a similarity in therapeutic effect with orlistat.
Usia dan Indeks Massa Tubuh dalam Kaitannya dengan Grading Karsinoma Mammae Invasif NST Jannati, Husna Bunga; Hardini, Niniek; Nugrohowati, Nunuk; Thadeus, Maria Selvester; Rahadiati, Familia Bella
Majalah Kedokteran Andalas Vol. 46 No. 3 (2023): Supplementary July 2023
Publisher : Faculty of Medicine, Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/mka.v46.i5.p836-846.2023

Abstract

Tujuan: Tujuan dari penulisan artikel ini adalah untuk mencari adanya keterkaitan antara indeks massa tubuh dan usia terhadap grading histopatologi karsinoma mammae invasif NST di RSPAD Gatot Soebroto tahun 2021. Metode: Penelitian kuantitatif analitik observasional menggunakan cross sectional sebagai desain penelitian. Pasien karsinoma mammae invasif NST yang tercatat pada tahun 2021 dirawat di RSPAD Gatot Soebroto adalah populasi, sampel adalah pasien yang telah disesuaikan dengan kriteria inklusi. Teknik simple random sampling dipilih menjadi teknik pengambilan sampel yang berasal dari data sekunder berupa rekam medis pasien, sampel digunakan sampel sebanyak 84 pasien. Indeks massa tubuh dan usia adalah variabel bebas dan grading adalah variabel terikat. Analisis univariat dilakukan untuk mengetahui karakteristik pasien berdasarkan usia, IMT, dan grading. Analisis bivariat bertujuan untuk mencari adanya keterkaitan antara variabel independen dan variabel dependen. Hasil: Tidak adanya hubungan yang bermakna ditemukan pada penelitian ini antara variabel IMT dengan grading dengan nilai p=0,685 sementara pada analisis mengenai keterkaitan usia dengan grading juga ditemukan tidak adanya hubungan dengan p=1. Kesimpulan: hubungan antara IMT dan usia dengan grading tidak ditemukan, kemungkinan tidak adanya hubungan akibat terbatasnya sampel. Subtipe molekuler dan status menopause sebagai faktor pembias.
Pemberdayaan Masyarakat dalam Mengendalikan Tekanan Darah di Posbindu Delima, Sawangan Depok: Community Empowerment in Controlling Blood Pressure at Posbindu Delima, Sawangan Depok Bustamam, Nurfitri; Hardini, Niniek; Fauziah, Cut
PengabdianMu: Jurnal Ilmiah Pengabdian kepada Masyarakat Vol. 9 No. 12 (2024): PengabdianMu: Jurnal Ilmiah Pengabdian kepada Masyarakat
Publisher : Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33084/pengabdianmu.v9i12.8317

Abstract

In 2023, data from Posbindu Delima, Sawangan Depok, showed that 37 residents had blood pressure ≥140/90 mmHg (hypertension), and 5 residents had already experienced complications from hypertension, such as stroke and heart disease. In response to this issue, a community service was conducted to help control the blood pressure of residents with hypertension by adopting a healthy lifestyle. The community service consists of three stages: disseminating guidelines for filling out the healthy lifestyle logbook and socializing the community service program, providing direct education and education using WhatsApp, and evaluating. The knowledge level, medication adherence, and health of residents with hypertension were measured before and after community service. The evaluation of healthy lifestyle implementation was based on logbook data. The 5-week community service was attended by 12 residents, most of whom (66.7%) were female with an average age of 60.6 ± 8.6 years. The community service results showed the knowledge level of residents increased significantly, but there was no statistical difference in medication adherence. After adopting a healthy lifestyle, there were significant health improvements, including increased residents with controlled blood pressure, weight loss, and reduced waist circumference. It can be inferred that the community service successfully increased knowledge and encouraged residents with hypertension to adopt a healthy lifestyle, resulting in controlled blood pressure.
Co-Authors A., Samsul Adyatma, Hilmi Andriyanto Aulia Chairani, Aulia Budi Maryoto, Agus Cakrahaya, Agus Cut Fauziah Jannati, Husna Bunga Kardiana, Yaya Maria Selvester Thadeus Nuralfilail, Zakiah Nada Nurfitri Bustamam Pritha Maya Savitri Rahadiati, Familia Bella Ramadhansyah, Reza Rifkia, Via Sukrisno, Adi Sunarya, Putri Amelia Wahyuni, Yosha Putri