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All Journal Jurnal Farmasi Galenika (Galenika Journal of Pharmacy) Jurnal Abdimas Madani dan Lestari (JAMALI) Jurnal Farmasi Indonesia SEGARA : Jurnal Pengabdian Kepada Masyarakat Journal of Research in Pharmacy and Pharmaceutical Sciences
Rifkia, Via
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Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Chemistry Civil Engineering, Building, Construction & Architecture Computer Science & IT Dentistry Education Health Professions Immunology & microbiology Medicine & Pharmacology Other

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Edukasi dan Pembuatan Hand Sanitizer dari Lemon Upaya Pencegahan Penularan Covid-19 Rifkia, Via; Dhigna Luthfiyani Citra Pradana; Rika Revina
Segara : Jurnal Pengabdian Kepada Masyarakat Vol 1 No 2 (2023): Vol. 1 No. 2 (2023): SEGARA : Jurnal Pengabdian Kepada Masyarakat
Publisher : Fakultas Kedokteran UPN "Veteran" Jakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33533/segara.v1i2.7289

Abstract

Kegagalan dalam menjaga kebersihan tangan adalah penyebab utama infeksi dan dapat mengakibatkan penyebaran mikroorganisme multi resisten di lingkungan sekitar. Menjaga kebersihan tangan dengan cara mencuci tangan adalah metode paling praktis dan efektif dalam pencegahan infeksi. Cara mencuci tangan yang paling tepat adalah dengan menggunakan sabun dan air bersih yang mengalir. Namun, penggunaan hand sanitizer dari bahan alam menjadi alternatif untuk membersihkan tangan di kala tidak ada air dan sabun.Tujuan kegiatan PkM ini adalah memberikan edukasi dan pembuatan hand sanitizer dengan menggunakan bahan alam upaya membantu pencegahan dari penularan infeksi virus, seperti COVID-19. Pada pembuatan hand sanitizer,memanfaatkan bahan alam yang ada disekitar mitra yaitu berupa jeruk lemon. jeruk lemon merupakan bahan alam yang memiliki aktivitas sebagai antiseptik, antibakteri, dan antivirus. Kegiatan PkM dilakukan dengan memberikan edukasi, pembuatan hand sanitaizer, serta pengisian pre test dan post test. Hasil PkM diperoleh peningkatan pengetahuan terkait wabah penyakit COVID-19 beserta proses penularannya, dan pemanfaatan bahan alam sebagai bahan pembuatan hand sanitizer dengan nilai rerata pre test 5,82%, sedangkan nilai rerata post test 8,95%.
EFFECTIVENESS OF GIVING MORINGA LEAF EXTRACT (MORINGA OLEIFERA) IN REDUCING BLOOD PRESSURE SYSTEMATIC REVIEW Rifkia, Via; Zahra, Rahmanita Kamila; Kolib, Abdul
Journal of Research in Pharmacy and Pharmaceutical Sciences Vol 2 No 2 (2023): Vol.2 No.2 DECEMBER (2023)
Publisher : Pharmacy Program, Faculty of Medicine, UPN Veteran Jakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33533/jrpps.v2i2.7229

Abstract

Hypertension, which is an increase in blood pressure, has a prevalence based on Riskesdas in 2018 at the age ≥18 years, which is around 34.1%. Various treatment methods have been developed because if hypertension is not treated it can cause symptoms and serious complications. Other than using chemical drugs such as beta-blockers or ACE inhibitors, people are starting to consider therapy with natural ingredients such as Moringa leaves (Moringa oleifera). It contains compounds that have an antihypertensive effect such as flavonoids and potassium. This study aims to determine the compound, effectiveness, and mechanism of Moringa leaf as an antihypertensive by using a systematic review method. This method is carried out by searching literature using certain keywords based on PRISMA-P, and then data from ten literatures is extracted to be discussed and concluded based on the objectives. The result, obtained various compounds in Moringa leaf extract have certain mechanisms in lowering blood pressure such as flavonoid compounds, such as kaempferol and quercetin, as well as other compounds such as several organic acids, potassium, and alkaloids. Moringa leaf extract also effectively lowers blood pressure in animals and humans with different doses. This study concludes that the administration of Moringa leaf extract can effectively reduce blood pressure due to the antihypertensive mechanism caused by the phytochemical content.
THE RELATIONSHIP OF COMPLIANCE WITH MEDICATION ON BLOOD PRESSURE STABILITY IN HYPERTENSION PATIENTS AT CINERE DISTRICT HEALTH CENTER 2023 Sumantri, Salsabila; rahmi, eldiza puji; Rifkia, Via; Pradana, Dhinga Luthfiyani
Journal of Research in Pharmacy and Pharmaceutical Sciences Vol 2 No 2 (2023): Vol.2 No.2 DECEMBER (2023)
Publisher : Pharmacy Program, Faculty of Medicine, UPN Veteran Jakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33533/jrpps.v2i2.7416

Abstract

Several reasons for hypertension sufferers who do not comply with taking medication will slow down healing time and worsen the patient's condition and can even cause death. This study aims to determine the characteristics of hypertensive patients at the Cinere Community Health Center, the results of antihypertensive therapy at the Cinere Community Health Center and to determine the relationship between adherence to medication use and the success of therapy at the Cinere Community Health Center. This research uses a correlational analytical research design. Based on the discussion above, it can be concluded that the characteristics of hypertensive patients at the Cinere Community Health Center are the majority aged 45-65 years, female with the highest education level being elementary school and having suffered for > 1 year. The majority of medication adherence among hypertensive patients at the Cinere Community Health Center is still relatively low. The success of therapy in hypertensive patients at the Cinere Community Health Center resulted in a reduction in blood pressure of 31 people and in patients who did not reduce blood pressure there were 71 people. There is a relationship between adherence to taking medication and blood pressure stability in hypertensive patients at the Cinere Community Health Center
Lipase Enzyme Inhibitory Activity of Jombang Leaves Extract (Taraxacum officinale F.H. Wigg): Aktivitas Penghambatan Enzim Lipase Ekstrak Daun Jombang (Taraxacum officinale F.H. Wigg) Secara In Vitro Muti, Annisa Farida; Adia, Risa; Rifkia, Via; Pradana, Dhigna Luthfiyani Citra
Jurnal Farmasi Galenika (Galenika Journal of Pharmacy) (e-Journal) Vol. 10 No. 1 (2024): (March 2024)
Publisher : Universitas Tadulako

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22487/j24428744.2024.v10.i1.16454

Abstract

Background: Obesity is a condition that occurs due to an imbalance between energy intake and expenditure. Lipase enzymes play an important role in the process of fat metabolism, making it a target in obesity treatment strategies. Jombang plant has been used for generations as an alternative treatment for various diseases. The main content of secondary metabolite compounds in jombang plants are phenolics, flavonoids, terpenoids, and alkaloids. Objective: This study was conducted to determine the activity and potential inhibition of jombang plant (Taraxacum officinale F.H. Wigg.) against lipase enzyme in vitro. Materials and Methods: The phytochemical screening was determined by a color change reaction with certain reagents, while total phenolic content was carried out using Folin-Ciocalteau reagent spectrophotometrically. The inhibitory activity of 96% ethanol extract of jombang leaves as well as orlistat as positive control was measured by titration method and using olive oil substrate. The extract concentrations used were 125 ppm, 250 ppm, and 500 ppm. Results: Jombang leaf extract contains alkaloid, phenolic, flavonoid and terpenoid compounds qualitatively. Determination of total phenolic content in 96% ethanol extract of jombang leaves was obtained at 12.69 ± 0.91 mgGAE/g. The highest percentage of inhibition was found at a concentration of 500 ppm which amounted to 103.85%. The difference in the percentage of inhibition in all groups showed no significant difference (Sig>0.05). Conclusion: This study shows that jombang leaf extract is able to inhibit lipase enzyme activity with the highest percentage of inhibition was 103,85%.
Sosialisasi Deteksi Dini dan Pengenalan Gejala Stadium Awal dan Akhir Kanker Serviks di Kecamatan Cinere: Indonesia Hardini, Niniek; Rifkia, Via; Wahyuni, Yosha Putri; Sukrisno, Adi
Jurnal Abdimas Madani dan Lestari (JAMALI) Volume 07, Issue 01, Maret 2025
Publisher : UII

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20885/jamali.vol7.iss1.art14

Abstract

Cervical cancer is a common cancer in women with an estimated 570,000 new cases in 2018 and represents 6.6% of all cancers in women. About 90% of cervical cancer deaths occur in low- and middle-income countries. High mortality rates from cervical cancer globally can be reduced through a comprehensive approach that includes prevention, early diagnosis, effective screening and treatment programs. Cervical cancer can be prevented with primary prevention. Primary prevention is to prevent the occurrence of Human Papillomavirus (HPV) infection with the advantage of not causing side effects, easy and effective. This prevention can be done using screening methods that are easy and inexpensive to do, such as Visual Inspection of Acetic Acid (IVA), which is visual inspection with acetic acid. The purpose of this activity is to increase knowledge about early detection of cervical cancer, symptoms at an early and late stage in Cinere Depok District. The assessment of understanding can be seen from the results of the pre-test and post-test. The results of this activity show that people in Cinere Depok District have understood the socialization of early detection of cervical cancer and recognize the symptoms of early and late stages of cervical cancer with an increase in the average value of post-test, which is 90% of the pre-test score.
Pengaruh Variasi Bahan: Pelarut dan Lama Ekstraksi Ultrasonik dari Ekstrak Daun Kelor terhadap Rendemen dan Kadar Total Fenol Rifkia, Via; Revina, Rika
JFIOnline | Print ISSN 1412-1107 | e-ISSN 2355-696X Vol. 15 No. 1 (2023): Jurnal Farmasi Indonesia
Publisher : Pengurus Pusat Ikatan Apoteker Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (428.215 KB) | DOI: 10.35617/jfionline.v15i1.126

Abstract

Abstract: Moringa (Moringa oleifera L.) is a plant that has a wide range of health benefits. The benefits of Moringa can be obtained from the leaf part. One of the compounds that are in Moringa leaves and have benefits is phenol compounds. Phenol compounds were tested from Moringa leaf extract obtained using the ultrasonic method. The ultrasonic method is an extraction method that can produce extracts effectively and efficiently. The purpose of this study was to determine the effect of variations in material concentration: solvent (1:10, 1:15, and 1:20) and extraction duration (10, 20, and 30 minutes) on the yield value and total phenol content of Moringa leaf extract. The extract obtained is then weighed and calculated the yield value. After that, Moringa leaf extract was tested for phytochemical screening and total phenol level test. Based on the results of the study, it showed that the highest amendment value of Moringa leaf extract was obtained from the ratio of ingredients: solvent 1:20 b / v with an extraction time of 30 minutes, which was 35.89%. Then the highest total phenol content results were obtained from moringa leaf ethanol extract at the ratio of ingredients: solvent 1:20 b / v with an extraction time of 30 minutes, which was 25,9 GAE/g.
Optimasi Perolehan dan Karakterisasi Serbuk Mucilago Hibiscus rosa-sinensis L. (MHR) sebagai Binder Tablet Prabowo, Imam; Putra, Iqbal Julian Rianda Pradana; Rifkia, Via
JFIOnline | Print ISSN 1412-1107 | e-ISSN 2355-696X Vol. 17 No. 1 (2025): Jurnal Farmasi Indonesia
Publisher : Pengurus Pusat Ikatan Apoteker Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35617/jfionline.v17i1.162

Abstract

This study aims to optimize the yield of MHR powder because the research conducted by Shah and Patel in 2010 was still very small, namely around 8%. Optimization was carried out by varying the soaking and heating times and then characterizing the MHR powder to test whether the MHR powder was a good candidate as a tablet binder. Characterization tests performed were organoleptic tests, particle size distribution, polysaccharide identification, swelling ratio, solubility, flow properties, viscosity, and water content. The most optimal MHR powder recovery was 1 hour of soaking time and 6 hours of heating time with a yield of 11.50 ± 1.40%. The results of the characterization of the MHR powder included: organoleptic test of the MHR powder was light brown, had a distinctive herbal odor and was tasteless, the particle size distribution test was in the range of 100-400 microns with the highest percentage of particles in the size of 186 μm, the swelling ratio was at 23 .47 ± 0.41, positive polysaccharide identification test, solubility was at 0.000426 ± 0.000034, viscosity was at 4520 ± 1224.42. Broadly speaking, MHR powder is a potential candidate as a tablet binder, that was proved from tablet formulation using MHR powder as binder resulted hardness, friability and disintegration time as well as formulation that using Avicel PH102 as binder.
Co-Authors Adia, Risa Annisa Farida Muti Hardini, Niniek Imam Prabowo, Imam Kolib, Abdul Pradana, Dhinga Luthfiyani Putra, Iqbal Julian Rianda Pradana Rahmi, Eldiza Puji Revina, Rika Rika Revina Sukrisno, Adi Sumantri, Salsabila Wahyuni, Yosha Putri Zahra, Rahmanita Kamila