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All Journal e-CliniC Jurnal e-Biomedik Jurnal Bios Logos JURNAL BIOMEDIK Jurnal Kedokteran Klinik
Mambo, Christi D.
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Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Health Professions Immunology & microbiology Medicine & Pharmacology

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Phytochemical Compounds and Antibacterial Test of Theonella cylindrica against Staphylococcus aureus and Escherichia coli Mambo, Christi D.; Warouw, Finny; Nangoy, Edward; Rumengan, Inneke; Kepel, Billy; Bara, Robert
JURNAL BIOS LOGOS Vol. 15 No. 2 (2025): JURNAL BIOS LOGOS
Publisher : Universitas Sam Ratulangi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35799/jbl.v15i2.59230

Abstract

Infectious diseases are a health problem faced by developing countries like Indonesia. This disease is caused by bacteria that attack humans. Improper use of antibiotics can cause bacterial resistance to antimicrobials. Antimicrobial resistance is the most significant public health threat, resulting in greater demand for finding new effective antimicrobials from natural products such as sea sponges. This research aimed to test the antibacterial activity of Theonella extract against Staphylococcus aureus and Escherichia coli and determine the class of chemical compounds contained therein. Research stages include sampling, sample preparation and extraction, qualitative phytochemical screening, making solutions, media creation, and antibacterial testing. The research showed that sponges metabolite compounds consisted of alkaloids, flavonoids, tannins, saponins, and phenolics. The diameter of the inhibition zone at concentrations of 80% and 100% showed potential antibacterial activity but more strongly inhibited the growth of Staphylococcus aureus bacteria than Escherichia coli bacteria.
Co-Authors Angelina Stevany Regina Masengi Arikalang, Giza E. E. Bawonte, Trivianto G. Billy Kepel Diana S. Purwanto Edward Nangoy, Edward Inneke F. M Rumengan Jimmy Posangi Kaligis, Clayton J. Korompis, Tifany T. Onibala, Aurelia R. Polii, Erfand Robert A. Bara Rondonuwu, Yohanes Amazia Zet Rue, Puella Seran, Ester Tarigan, Paulus B. Umboh, Octavianus Warouw, Finny