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All Journal Jurnal Penelitian Pendidikan IPA (JPPIPA) JOPS (Journal Of Pharmacy and Science) Journal of Pharmaceutical Science and Herbal Technology Jurnal Novem Medika Farmasi
Auliah, Nielma
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Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Education Health Professions Immunology & microbiology Materials Science & Nanotechnology Medicine & Pharmacology Physics Public Health

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THE FORMULATION OF CREAM PREPARATIONS BLUSH ON OF ETANOL EXTRACT FROM MIANA PURPLE LEAVES (Coleus scutellarioides L.) AS BLUSHER Suryanita; Fitrahmia S, Nur; Auliah, Nielma; Bachri, Nurjannah
Journal of Pharmaceutical Science and Herbal Technology Vol. 9 No. 1 (2024): Journal of Pharmaceutical Science and Herbal Technology
Publisher : STIKES Nani Hasanuddin Makassar

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Abstract

Anthocyanin is a chemical compound found in purple miana leaves and plays an important role in providing color. Purple miana leaf extract can be used as a natural coloring in blush on cream preparations. The aim of this research is to determine whether purple miana leaf extract (Coleus scutellarioides L) can be formulated in the form of a blush cream dosage form that is physically and chemically stable. The research method used was experimental research by making blush on preparation formulations with concentrations of 7.5%, 10% and 12.5% ​​and evaluating the preparations using physicochemical, irritation tests and hedonic tests. The research results showed that blush on formulations with concentrations of 7.5%, 10% and 12.5% ​​were physically and chemically stable and in the hedonic/preference test the most preferred formulation was the formulation with a concentration of 12.5%. The conclusion of this research is that the ethanol extract of purple miana leaves (Coleus Scutellarioides L) can be formulated in the form of a blush cream dosage form that is physically and chemically stable.
Efektivitas Antidiare Ekstrak Buah Terong Takokak (Solanum torvum) Terhadap Hewan Uji Mencit (Mus musculus) Diinduksi Dengan Minyak Jarak (Oleum ricini) Najamuddin, Mirfaidah; Auliah, Nielma; Iriani, Nova; wahyuni; yustisi, Andi juella; Karim, Suhrah Febrina; Junita, Nurfitria; SG, Noviatri
Jurnal Novem Medika Farmasi Vol. 1 No. 2: volume 1 Issue 2
Publisher : Program Studi Farmasi, Universitas Islam Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59638/junomefar.v1i2.611

Abstract

Ekstrak etanol buah terong Takokak (Solanum torvum) mengandung tannin yang berfungsi sebagai anti diare. Penelitian ini bertujuan untuk melihat efektivitas antidiare ekstrak buah terong takokak (Solanum torvum) terhadap hewan uji mencit (Mus musculus). Buah terong Takokak melewati proses maserasi, kemudian dibuat menjadi tiga dosis yaitu 15, 20, dan 25 mg/kg BB, dengan menggunakan minyak jarak (Oleum ricini) diinduksikan kepada 5 kelompok perlakuan hewan uji, dan diamati konsistensi feses dan bobot feses yang dihasilkan pada 4 jam perlakuan dibandingkan dengan loperamide 2 mg sebagai kontrol positif. Hasil yang diperoleh menunjukkan pada masing-masing kelompok ekstrak 15 mg/kgBB, 20 mg/kgBB, dan 25 mg/kgBB dengan kontrol negatif Na.CMC diperoleh hasil p< 0.05 hanya pada dosis 25 mg/kgBB dan kontrol positif loperamid, artinya memiliki kemampuan sebagai antidiare yang baik daripada kontrol negatif. Disimpulkan bahwa dosis 25 mg/kgBB merupakan dosis yang paling efektif sebagai antidiare.
Formulasi dan Uji Efektivitas Sediaan Lip cream dari Ekstrak Etanol Biji Buah Merah (Pandanus conoideus L) sebagai Pewarna Alami dengan Menggunakan Metode DPPH (1,1-Difenil-2-Pikrihidrazil) Primadani, Nur Baetty; Alyidrus, Rugayyah; Farid, Nurfiddin; Auliah, Nielma
JURNAL FARMASI DAN MAKANAN Vol 7 No 1 (2023): Journal of Pharmacy and Science
Publisher : LPPM Universitas Abdurrab

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36341/jops.v7i1.4173

Abstract

Formulation and Effectiveness Test of Lip Cream Preparations from Ethanol Extract of Red Fruit Seeds (Pandanus conoideus L) as A Natural Dye Using The DPPH (1,1-Diphenyl-2-Pikrihidrazil) Method. Red fruit seeds are botanical specimens that possess keratenoid chemicals, specifically b-carotene and a-carotene, which exhibit antioxidant properties. The objective of this study is to develop a stable Lipcream formulation and measure the IC50 value of the lipcream prepared from the ethanol extract of red fruit seeds (Pandanus conoideus L), which has antioxidant properties. An experimental research approach utilizing a solvent maceration technique with a solvent concentration of 96%. The obtained concentrated extract was subjected to rotation, followed by the fabrication of solutions with concentrations of 2%, 4%, and 6%, utilizing beeswax as a thickening agent. Kaolin is used as a texturizer. The emollients used are castor oil, cetyl alcohol, and dimethicon. Methyl paraben and propyl paraben are utilized as preservatives. Titanium dioxide serves as a pigment. The scent of vanilla. The preparation was evaluated by a cycling test consisting of 6 cycles over a period of 12 days. Organoleptic observations revealed a semi-solid texture, cream-like form, and a vanilla scent. The homogeneity test yielded consistent results, with pH measurements exceeding 0.05p, spreadability test results surpassing 0.05p, and adhesiveness test results meeting the specified standards. In addition to doing antioxidant testing, the DPPH method is employed using a UV-Vis spectrophotometer. The research findings indicate that the ethanol extract derived from red fruit seeds (Pandanus conoideus L) can be effectively made into a stable lip cream formulation, both in terms of its physical and chemical properties. The IC50 values obtained from the lip cream formulation including the ethanol extract of red fruit seeds (Pandanus conoideus L) were 59,496 ppm, 52,817 ppm, and 5,581 ppm, respectively. Formula 3 contains the most potent antioxidant value among all lip cream preparations.
Test the Antioxidant Effectiveness of Oyster Mushroom (Pleurotus ostreatus) Ethyl Acetate Fraction Cream Formula using FRAP (Ferric Reducing Antioxidant Power) and ABTS (2,2'-azino-bis (3-3) ethylbenzothiazoline-6-sulphonic acid) Methods) Nadjamuddin, Mirfaidah; Auliah, Nielma; Mulyadin; Tajuddin, Zakiah; Andriawan, Riki
Jurnal Penelitian Pendidikan IPA Vol 9 No 12 (2023): December
Publisher : Postgraduate, University of Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jppipa.v9i12.6118

Abstract

Antioxidants are compounds that can fight the influence of free radical molecules due to chemical reactions and metabolic events in the body. Phenolic compounds work to reduce the reaction of increasing the oxidation number, and are able to reduce highly reactive free radicals, lipid peroxidation processes, and metal oxides that can be obtained from oyster mushrooms. This study aims to make an antioxidant cream preparation and measure the IC50 value by conducting an antioxidant test of the ethyl acetate fraction of oyster mushroom (Pleurotus ostreotus) cream using FRAP (ferric reducing antioxidant power) and ABTS (2.2'-azino-bis (3-3) ethylbenzothiazoline-6-sulphonic acid) methods. The methods used are FRAP and ABTS where oyster mushrooms go through a liquid-liquid partition process and are made into cream preparations with formula concentrations of 2%, 4% and 6%, then their antioxidant activity is seen. The results of measuring three cream formulas obtained an IC50 value using the FRAP method of 110.12 bpj, and an IC50 value using the ABTS method of 84.61 bpj. The conclusion was that the IC50 value using the FRAP method (110.12 bpj) had medium category activity and the IC50 value using the ABTS method (84.61 bpj) had strong category activity.
Co-Authors Alyidrus, Rugayyah Andriawan, Riki Farid, Nurfiddin Fitrahmia S, Nur Iriani, Nova Junita, Nurfitria Karim, Suhrah Febrina Mulyadin Nadjamuddin, Mirfaidah Najamuddin, Mirfaidah Nurjannah Bachri, Nurjannah Primadani, Nur Baetty SG, Noviatri Suryanita Tajuddin, Zakiah WAHYUNI yustisi, Andi juella