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All Journal BIOEDUKASI Jurnal Pascapanen dan Bioteknologi Kelautan dan Perikanan JURNAL FARMASIMED (JFM) Indonesia Natural Research Pharmaceutical Journal (INRPJ) Pharmacy Action Journal KAMI MENGABDI Indonesian Journal of Pharmaceutical Research
Panjaitan, Riong seulina
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Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemistry Education Electrical & Electronics Engineering Energy Engineering Environmental Science Health Professions Immunology & microbiology Library & Information Science Medicine & Pharmacology Public Health Social Sciences Transportation Other

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Journal : JURNAL FARMASIMED (JFM)

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Identification, Characterization and Antifungal Activity Test of Chemical Compounds from Methanol Extract of Macroalgae Padina australis Against Dandruff Fungus Malassezia globosa Djohansah, Violetta; Panjaitan, Riong Seulina; Zuraida Sagala
Jurnal FARMASIMED (JFM) Vol 8 No 1 (2025): Jurnal Farmasimed (JFM)
Publisher : Fakultas Farmasi Institut Kesehatan Medistra Lubuk Pakam

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35451/3mat6358

Abstract

Padina australis is a species of brown macroalgae with potential as a natural source of bioactive compounds, including antifungal agents. This study aimed to identify the functional groups present in the methanolic extract of Padina australis using Fourier Transform Infrared (FTIR) spectroscopy and to evaluate its antifungal activity against Malassezia globosa through the disk diffusion method. FTIR analysis revealed the presence of hydroxyl (3433.41 cm⁻¹), aliphatic C–H (2916.47 cm⁻¹), carbonyl (1735.99 and 1643.41 cm⁻¹), amine (1573.97 and 1242.20 cm⁻¹), C–O, and carboxylate (COO⁻) groups, indicating key secondary metabolites such as flavonoids, phenols, esters, amines, and polysaccharides. Antifungal testing showed that the extract at a concentration of 100 ppm produced the largest inhibition zone (16.58 ± 4.71 mm), while the minimum inhibitory concentration (MIC) was determined at 12.5 ppm with an inhibition zone diameter ≥12 mm. These findings suggest that Padina australis holds promising potential as a natural source for developing antifungal therapies against Malassezia globosa.
Co-Authors Afikah, Hana Tri Anastasya, Millenia Putri Andrian, Rahmat Ardian, Kristian Derius Aslawiyah, Siti Rabiaatul Asriyanti, Laila Safa Djohansah, Violetta Elawati, Nur Febriani, Ike Ghassani, Fatiha Azka Hafiz, Muhammad Ariqoh Langit, Vinsensia Asahi Sulan Lenoera, Agnes M. Yogi Riyantama Isjoni Meze, Maria Fortunata Nurwijayanti parma, syafriadi kurnia Pradipta, Oki Purwati Purwati Putranto, Haidar Dwi Putri, Hervita Reza, Fakhrur Sabrina, Rorina Sagala, Zuraida Salsabilla, Zuli Astuti Septiyani, Anisah Simanjuntak, Yulia Verawati Simatupang, Angel Maria Sinambela, Rio Pandi Siti Aisyah Suciati, Lily Sumantri Sumantri Suryo, Nabila Dwi Wijaya, Bagas Eva Yosepin, Elpina Yulius Evan Christian Zuraida Sagala